Topically applied vitamin E prevents massive cutaneous inflammatory and oxidative stress responses induced by double application of 12-O-tetradecanoylphorbol-13-acetate (TPA) in mice Fulltext Access 11 Pages 2008
Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation Fulltext Access 11 Pages 2008
A dietary supplement for female sexual dysfunction, Avlimil, stimulates the growth of estrogen-dependent breast tumors (MCF-7) implanted in ovariectomized athymic nude mice Fulltext Access 11 Pages 2008
Effects of dietary fats and proteins on rat testicular steroidogenic enzymes and serum testosterone levels Fulltext Access 11 Pages 2008
Protective effect of pine (Pinus morrisonicola Hay.) needle on LDL oxidation and its anti-inflammatory action by modulation of iNOS and COX-2 expression in LPS-stimulated RAW 264.7 macrophages Fulltext Access 11 Pages 2008
No enhancing effects of diacylglycerol oil on tumor development in a medium-term multi-organ carcinogenesis bioassay using male F344 rats Fulltext Access 11 Pages 2008
A 90-day subchronic toxicity study of nivalenol, a trichothecene mycotoxin, in F344 rats Fulltext Access 11 Pages 2008
Performing IgE serum testing due to bioinformatics matches in the allergenicity assessment of GM crops Fulltext Access 11 Pages 2008
Changes in the hepatic gene expression profile in a rat model of chronic ethanol treatment Fulltext Access 11 Pages 2008
Neurobehavioral assessment of rats exposed to low doses of PCB126 and methyl mercury during development Fulltext Access 11 Pages 2008
Aconitum and Delphinium alkaloids: “Drug-likeness” descriptors related to toxic mode of action Fulltext Access 11 Pages 2008
Chemopreventive and therapeutic modulation of green tea polyphenols on drug metabolizing enzymes in 4-Nitroquinoline 1-oxide induced oral cancer Fulltext Access 11 Pages 2008
The Inhalation toxicity of di- and triethanolamine upon repeated exposure Fulltext Access 11 Pages 2008
Hypolipidimic and antioxidant activities of oleuropein and its hydrolysis derivative-rich extracts from Chemlali olive leaves Fulltext Access 11 Pages 2008
Cu2+ is required for pyrrolidine dithiocarbamate to inhibit histone acetylation and induce human leukemia cell apoptosis Fulltext Access 11 Pages 2008
Oral administration of diphenyl diselenide protects against cadmium-induced liver damage in rats Fulltext Access 11 Pages 2008
Prevention of prostate cancer through custom tailoring of chemopreventive regimen Fulltext Access 11 Pages 2008
Salubrious effect of Kalpaamruthaa, a modified indigenous preparation in adjuvant-induced arthritis in rats-A biochemical approach Fulltext Access 11 Pages 2008
Hepatoprotective effects of Solanum nigrum Linn extract against CCl4-iduced oxidative damage in rats Fulltext Access 11 Pages 2008
The roles of amino acid residues at positions 216 and 219 in the structural stability and metabolic functions of rat cytochrome P450 2D1 and 2D2 Fulltext Access 11 Pages 2008
A review of critical factors in the conduct and interpretation of the human repeat insult patch test Fulltext Access 11 Pages 2008
Molecular targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) within the zebrafish ovary: Insights into TCDD-induced endocrine disruption and reproductive toxicity Fulltext Access 11 Pages 2008
The relationship of maternal and fetal toxicity in developmental toxicology bioassays with notes on the biological significance of the “no observed adverse effect level” Fulltext Access 11 Pages 2008
In vivo and in vitro effects of the organochlorine pesticides DDT, TCPM, methoxychlor, and lindane on the female reproductive tract of mammals: A review Fulltext Access 11 Pages 2008
Brown Norway rat asthma model of diphenylmethane-4,4′-diisocyanate (MDI): Impact of vehicle for topical induction Fulltext Access 11 Pages 2008
The utility of the K6/ODC transgenic mouse as an alternative short term dermal model for carcinogenicity testing of pharmaceuticals Fulltext Access 11 Pages 2008
Biomonitoring Equivalents (BE) dossier for acrylamide (AA) (CAS No. 79-06-1) Fulltext Access 11 Pages 2008
Guidelines for the communication of Biomonitoring Equivalents: Report from the Biomonitoring Equivalents Expert Workshop Fulltext Access 11 Pages 2008
Identification and enumeration of asbestos fibers in the mining environment: Mission and modification to the Federal Asbestos Standard Fulltext Access 11 Pages 2008
Quercus infectoria galls possess antioxidant activity and abrogates oxidative stress-induced functional alterations in murine macrophages Fulltext Access 11 Pages 2008
Replacement of in vivo acute oral toxicity studies by in vitro cytotoxicity methods: Opportunities, limits and regulatory status Fulltext Access 11 Pages 2008
A study of airborne chrysotile concentrations associated with handling, unpacking, and repacking boxes of automobile clutch discs Fulltext Access 11 Pages 2008
A randomized, controlled exposure study in adult smokers of full flavor Marlboro cigarettes switching to Marlboro Lights or Marlboro Ultra Lights cigarettes Fulltext Access 11 Pages 2008
Pre-bled-young-rats in genotoxicity testing: A model for peripheral blood micronucleus assay Fulltext Access 11 Pages 2008
Behavioral responses during the initial exposures to a low dose of cocaine in late preweanling and adult rats Fulltext Access 11 Pages 2008
Risk of learning and behavioral disorders following prenatal and early postnatal exposure to tetrachloroethylene (PCE)-contaminated drinking water Fulltext Access 11 Pages 2008
Synergistic effects of ferritin and propolis in modulation of beryllium induced toxicogenic alterations Fulltext Access 11 Pages 2008
Involvement of cyclin D1/CDK4 and pRb mediated by PI3K/AKT pathway activation in Pb2+-induced neuronal death in cultured hippocampal neurons Fulltext Access 11 Pages 2008
Aromatase inhibiting and combined estrogenic effects of parabens and estrogenic effects of other additives in cosmetics Fulltext Access 11 Pages 2008
Biomarkers of oxidative stress and DNA damage in agricultural workers: A pilot study Fulltext Access 11 Pages 2008
Polymeric black tea polyphenols inhibit 1,2-dimethylhydrazine induced colorectal carcinogenesis by inhibiting cell proliferation via Wnt/β-catenin pathway Fulltext Access 11 Pages 2008
Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation Fulltext Access 11 Pages 2008
Nonalcoholic steatohepatitic (NASH) mice are protected from higher hepatotoxicity of acetaminophen upon induction of PPARα with clofibrate Fulltext Access 11 Pages 2008
Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte injury: Multiple protective roles of cyclosporin A Fulltext Access 11 Pages 2008
Signaling at G-protein-coupled serotonin receptors: recent advances and future research directions Fulltext Access 11 Pages 2008
A role for the 5-HT1A, 5-HT4 and 5-HT6 receptors in learning and memory Fulltext Access 11 Pages 2008
Distinct MAPK signaling pathways, p21 up-regulation and caspase-mediated p21 cleavage establishes the fate of U937 cells exposed to 3-hydrogenkwadaphnin: Differentiation versus apoptosis Fulltext Access 11 Pages 2008
Suppression of autophagy enhances the cytotoxicity of the DNA-damaging aromatic amine p-anilinoaniline Fulltext Access 11 Pages 2008
A human intervention study with foods containing natural Ah-receptor agonists does not significantly show AhR-mediated effects as measured in blood cells and urine Fulltext Access 11 Pages 2008
Cinnamaldehyde inhibits the tumor necrosis factor-α-induced expression of cell adhesion molecules in endothelial cells by suppressing NF-κB activation: Effects upon IκB and Nrf2 Fulltext Access 11 Pages 2008
Alternate AChE-R variants facilitate cellular metabolic activity and resistance to genotoxic stress through enolase and RACK1 interactions Fulltext Access 11 Pages 2008
Reduction of myeloid suppressor cell derived nitric oxide provides a mechanistic basis of lead enhancement of alloreactive CD4+ T cell proliferation Fulltext Access 11 Pages 2008
Subhepatotoxic exposure to arsenic enhances lipopolysaccharide-induced liver injury in mice Fulltext Access 12 Pages 2008
Proteomic assessment of sulfur mustard-induced protein adducts and other protein modifications in human epidermal keratinocytes Fulltext Access 12 Pages 2008
17α-Estradiol arrests cell cycle progression at G2/M and induces apoptotic cell death in human acute leukemia Jurkat T cells Fulltext Access 12 Pages 2008
Dietary turmeric modulates DMBA-induced p21ras, MAP kinases and AP-1/NF-κB pathway to alter cellular responses during hamster buccal pouch carcinogenesis Fulltext Access 12 Pages 2008
Promoter analysis of TCDD-inducible genes in a thymic epithelial cell line indicates the potential for cell-specific transcription factor crosstalk in the AhR response Fulltext Access 12 Pages 2008
Involvement of MAPKs, NF-κB and p300 co-activator in IL-1β-induced cytosolic phospholipase A2 expression in canine tracheal smooth muscle cells Fulltext Access 12 Pages 2008
Profiling of benzophenone derivatives using fish and human estrogen receptor-specific in vitro bioassays Fulltext Access 12 Pages 2008
Propofol pretreatment attenuates LPS-induced granulocyte–macrophage colony-stimulating factor production in cultured hepatocytes by suppressing MAPK/ERK activity and NF-κB translocation Fulltext Access 12 Pages 2008
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin administration and high-fat diet on the body weight and hepatic estrogen metabolism in female C3H/HeN mice Fulltext Access 12 Pages 2008
Induction of CYP1A1 and CYP1B1 by benzo(k)fluoranthene and benzo(a)pyrene in T-47D human breast cancer cells: Roles of PAH interactions and PAH metabolites Fulltext Access 12 Pages 2008
Activation of estrogen receptor signaling by the dioxin-like aryl hydrocarbon receptor agonist, 3,3â²,4,4â²,5-Pentachlorobiphenyl (PCB126) in salmon in vitro system Fulltext Access 12 Pages 2008
Development and characterization of P-glycoprotein 1 (Pgp1, ABCB1)-mediated doxorubicin-resistant PLHC-1 hepatoma fish cell line Fulltext Access 12 Pages 2008
Inhibition of the adenine nucleotide translocator by N-acetyl perfluorooctane sulfonamides in vitro Fulltext Access 12 Pages 2008
Biological interactions of quantum dot nanoparticles in skin and in human epidermal keratinocytes Fulltext Access 12 Pages 2008
SNPs of GSTM1, T1, P1, epoxide hydrolase and DNA repair enzyme XRCC1 and risk of urinary transitional cell carcinoma in southwestern Taiwan Fulltext Access 12 Pages 2008
Arsenite-induced mitotic death involves stress response and is independent of tubulin polymerization Fulltext Access 12 Pages 2008
1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells Fulltext Access 12 Pages 2008
Application of drug metabolising mutants of cytochrome P450 BM3 (CYP102A1) as biocatalysts for the generation of reactive metabolites Fulltext Access 12 Pages 2008
Changing ratios of omega-6 to omega-3 fatty acids can differentially modulate polychlorinated biphenyl toxicity in endothelial cells Fulltext Access 12 Pages 2008
Dithiocarbamates and viral IL-10 collaborate in the immortalization and evasion of immune response in EBV-infected human B lymphocytes Fulltext Access 12 Pages 2008
A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat Fulltext Access 12 Pages 2008
Mitochondrial toxicity and antioxidant activity of a prenylated flavonoid isolated from Dalea elegans Fulltext Access 12 Pages 2008
Cyclin-dependent kinase 9: a key transcriptional regulator and potential drug target in oncology, virology and cardiology Fulltext Access 12 Pages 2008
Laboratory diet profoundly alters gene expression and confounds genomic analysis in mouse liver and lung Fulltext Access 12 Pages 2008
Computer-aided drug discovery and development (CADDD): In silico-chemico-biological approach Fulltext Access 12 Pages 2008
In vitro cytotoxic potential of Polyalthia longifolia on human cancer cell lines and induction of apoptosis through mitochondrial-dependent pathway in HL-60 cells Fulltext Access 12 Pages 2008
Intracellular GSH levels rather than ROS levels are tightly related to AMA-induced HeLa cell death Fulltext Access 12 Pages 2008
The crucial protective role of glutathione against tienilic acid hepatotoxicity in rats Fulltext Access 12 Pages 2008
The contribution of c-Jun N-terminal kinase activation and subsequent Bcl-2 phosphorylation to apoptosis induction in human B-cells is dependent on the mode of action of specific stresses Fulltext Access 12 Pages 2008
Inorganic arsenic exposure affects pain behavior and inflammatory response in rat Fulltext Access 12 Pages 2008
Role of mitogen-activated protein kinases in aryl hydrocarbon receptor signaling Fulltext Access 12 Pages 2008
Receptor-independent, vacuolar ATPase-mediated cellular uptake of histamine receptor-1 ligands: Possible origin of pharmacological distortions and side effects Fulltext Access 12 Pages 2008
Involvement of reactive oxygen species/c-Jun NH2-terminal kinase pathway in kotomolide A induces apoptosis in human breast cancer cells Fulltext Access 12 Pages 2008