Oxidative stress induced by destruxin from Metarhizium anisopliae (Metch.) involves changes in glutathione and ascorbate metabolism and instigates ultrastructural changes in the salivary glands of Spodoptera litura (Fab.) larvae Fulltext Access 11 Pages 2008
Modulation of voltage-gated Na+ and K+ channels by pumiliotoxin 251D: A “joint venture” alkaloid from arthropods and amphibians Fulltext Access 11 Pages 2008
Taiwan cobra cardiotoxins induce apoptotic death of human neuroblastoma SK-N-SH cells mediated by reactive oxygen species generation and mitochondrial depolarization Fulltext Access 11 Pages 2008
Isolation and structural characterization of a new fibrin(ogen)olytic metalloproteinase from Bothrops moojeni snake venom Fulltext Access 11 Pages 2008
Immunological responses of the Manila clam (Ruditapes philippinarum) with varying parasite (Perkinsus olseni) burden, during a long-term exposure to the harmful alga, Karenia selliformis, and possible interactions Fulltext Access 11 Pages 2008
Expression of mRNAs coding for VAP1/crotastatin-like metalloproteases in the venom glands of three South American pit vipers assessed by quantitative real-time PCR Fulltext Access 11 Pages 2008
Characterization of a novel pro-coagulant metalloprotease (RVBCMP) possessing α-fibrinogenase and tissue haemorrhagic activity from venom of Daboia russelli russelli (Russell's viper): Evidence of distinct coagulant and haemorrhagic sites in RVBCMP Fulltext Access 11 Pages 2008
Partial purification of cytolytic venom proteins from the box jellyfish, Chironex fleckeri Fulltext Access 11 Pages 2008
Generation of ammodytoxin-anti-cathepsin B immuno-conjugate as a model for delivery of secretory phospholipase A2 into cancer cells Fulltext Access 11 Pages 2008
Ultrastructural damage to heart tissue from repeated oral exposure to yessotoxin resolves in 3 months Fulltext Access 11 Pages 2008
Multivalent binding of ricin to bovine serum albumin-based neoglycoconjugates Fulltext Access 11 Pages 2008
Inhibition of lung tumor colonization and cell migration with the disintegrin crotatroxin 2 isolated from the venom of Crotalus atrox Fulltext Access 11 Pages 2008
Intersexual variations in Northern (Missulena pruinosa) and Eastern (M. bradleyi) mouse spider venom Fulltext Access 11 Pages 2008
Hepatic recovery after damage produced by sub-chronic intoxication with the cyanotoxin microcystin LR Fulltext Access 11 Pages 2008
DNA double-strand break and chromosomal rejoining defects with misrejoining in Nijmegen breakage syndrome cells Fulltext Access 11 Pages 2008
Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA Fulltext Access 11 Pages 2008
Rad52 sumoylation and its involvement in the efficient induction of homologous recombination Fulltext Access 11 Pages 2008
The NER protein Rad33 shows functional homology to human Centrin2 and is involved in modification of Rad4 Fulltext Access 11 Pages 2008
Characterization of CHO XPF mutant UV41: Influence of XPF heterozygosity on double-strand break-induced intrachromosomal recombination Fulltext Access 11 Pages 2008
The histone methylase Set2p and the histone deacetylase Rpd3p repress meiotic recombination at the HIS4 meiotic recombination hotspot in Saccharomyces cerevisiae Fulltext Access 11 Pages 2008
Both replication bypass fidelity and repair efficiency influence the yield of mutations per target dose in intact mammalian cells induced by benzo[a]pyrene-diol-epoxide and dibenzo[a,l]pyrene-diol-epoxide Fulltext Access 11 Pages 2008
Biochemical studies with DNA polymerase β and DNA polymerase β-PAK of Trypanosoma cruzi suggest the involvement of these proteins in mitochondrial DNA maintenance Fulltext Access 11 Pages 2008
Suppressed expression of non-DSB repair genes inhibits gamma-radiation-induced cytogenetic repair and cell cycle arrest Fulltext Access 11 Pages 2008
Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: Current and developing technologies Fulltext Access 11 Pages 2008
Influence of method of systemic administration of adenovirus on virus-mediated toxicity: Focus on mortality, virus distribution, and drug metabolism Fulltext Access 11 Pages 2008
Safety and secondary pharmacology: Successes, threats, challenges and opportunities Fulltext Access 11 Pages 2008
Creation of a digital slide and tissue microarray resource from a multi-institutional predictive toxicology study in the rat: An initial report from the PredTox group Fulltext Access 11 Pages 2008
Prevalidation of in vitro continuous flow exposure systems as alternatives to in vivo inhalation safety evaluation experimentations: Outcome from MAAPHRI-PCRD5 research program Fulltext Access 11 Pages 2008
The antiulcer effect of Croton cajucara Benth in normoproteic and malnourished rats Fulltext Access 11 Pages 2008
Phytotherapy and psychiatry: Bibliometric study of the scientific literature from the last 20 years Fulltext Access 11 Pages 2008
Sclerocarya birrea [(A. Rich.) Hochst.] [Anacardiaceae] stem-bark ethanolic extract (SBE) modulates blood glucose, glomerular filtration rate (GFR) and mean arterial blood pressure (MAP) of STZ-induced diabetic rats Fulltext Access 11 Pages 2008
Anti-inflammatory and analgesic effects and molecular mechanisms of JCICM-6, a purified extract derived from an anti-arthritic Chinese herbal formula Fulltext Access 11 Pages 2008
The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction – an evaluation using primates, rabbit and rat Fulltext Access 11 Pages 2008
Genetic susceptibility to malignant pleural mesothelioma and other asbestos-associated diseases Fulltext Access 11 Pages 2008
Mechanism of oxidative DNA damage repair and relevance to human pathology Fulltext Access 11 Pages 2008
Multiple roles of nicotine on cell proliferation and inhibition of apoptosis: Implications on lung carcinogenesis Fulltext Access 11 Pages 2008
Assessment of the genotoxic potential of benzo(a)pyrene and pp′-dichlorodiphenyldichloroethylene in Zebra mussel (Dreissena polymorpha) Fulltext Access 11 Pages 2008
Study on potential effects of “902-MHz GSM-type Wireless Communication Signals” on DMBA-induced mammary tumours in Sprague–Dawley rats Fulltext Access 11 Pages 2008
DNA-damaging activity and mutagenicity of 16 newly synthesized thiazolo[5,4-a]acridine derivatives with high photo-inducible cytotoxicity Fulltext Access 11 Pages 2008
Cigarette smoking and KRAS oncogene mutations in sporadic colorectal cancer: Results from the Netherlands Cohort Study Fulltext Access 11 Pages 2008
Profiles and levels of fatty acid esters of okadaic acid group toxins and pectenotoxins during toxin depuration, Part I: Brown crab (Cancer pagurus) Fulltext Access 11 Pages 2008
Properties and cDNA cloning of antihemorrhagic factors in sera of Chinese and Japanese mamushi (Gloydius blomhoffi) Fulltext Access 11 Pages 2008
Koninginins, phospholipase A2 inhibitors from endophytic fungus Trichoderma koningii Fulltext Access 11 Pages 2008
Meta-analysis of depression and substance use and impairment among cocaine users Fulltext Access 11 Pages 2008
A Phase 3 placebo-controlled, double-blind, multi-site trial of the alpha-2-adrenergic agonist, lofexidine, for opioid withdrawal Fulltext Access 11 Pages 2008
Past 12-month and lifetime comorbidity and poly-drug use of ecstasy users among young adults in the United States: Results from the National Epidemiologic Survey on Alcohol and Related Conditions Fulltext Access 11 Pages 2008
The prognostic implications of DSM-IV abuse criteria in drinking adolescents Fulltext Access 11 Pages 2008
Role of individual, peer and family factors in the use of cannabis and other illicit drugs: A longitudinal analysis among Finnish adolescent twins Fulltext Access 11 Pages 2008
Improving linkage with substance abuse treatment using brief case management and motivational interviewing Fulltext Access 11 Pages 2008
Transition to injection drug use among street youth—A qualitative analysis Fulltext Access 11 Pages 2008
Non-prescribed use of pain relievers among adolescents in the United States Fulltext Access 11 Pages 2008
Gender identity and substance use among students in two high schools in Monterrey, Mexico Fulltext Access 11 Pages 2008
Further evidence of an association between adolescent bipolar disorder with smoking and substance use disorders: A controlled study Fulltext Access 11 Pages 2008
Developmental trajectories of criteria of nicotine dependence in adolescence Fulltext Access 11 Pages 2008
Present and lifetime comorbidity of tobacco, alcohol and drug use in eating disorders: A European multicenter study Fulltext Access 11 Pages 2008
Randomized, placebo-controlled trial of bupropion for the treatment of methamphetamine dependence Fulltext Access 11 Pages 2008
Social reward-conditioned place preference: A model revealing an interaction between cocaine and social context rewards in rats Fulltext Access 11 Pages 2008
Severity of drug dependence, economic pressure and HIV-related risk behaviors among non-institutionalized female injecting drug users who are also sex workers in China Fulltext Access 11 Pages 2008
Test of measurement invariance of the FTND across demographic groups: Assessment, effect size, and prediction of cessation Fulltext Access 11 Pages 2008
Brief alcohol intervention for general hospital inpatients: A randomized controlled trial Fulltext Access 11 Pages 2008
Ethanol drinking in rodents: is free-choice drinking related to the reinforcing effects of ethanol? Fulltext Access 11 Pages 2008
Diet, alcohol consumption, and serum lipid levels of the middle-aged and elderly in the Guangxi Bai Ku Yao and Han populations Fulltext Access 11 Pages 2008
The relationships of sociodemographic factors, medical, psychiatric, and substance-misuse co-morbidities to neurocognition in short-term abstinent alcohol-dependent individuals Fulltext Access 11 Pages 2008
Effect of naltrexone during extinction of alcohol-reinforced responding and during repeated cue-conditioned reinstatement sessions in a cue exposure style treatment Fulltext Access 11 Pages 2008
Neuropeptide Y suppresses ethanol drinking in ethanol-abstinent, but not non-ethanol-abstinent, Wistar rats Fulltext Access 11 Pages 2008
Cell-type-specific consequences of nucleotide excision repair deficiencies: Embryonic stem cells versus fibroblasts Fulltext Access 11 Pages 2008
The human set and transposase domain protein Metnase interacts with DNA Ligase IV and enhances the efficiency and accuracy of non-homologous end-joining Fulltext Access 11 Pages 2008
APLF (C2orf13) facilitates nonhomologous end-joining and undergoes ATM-dependent hyperphosphorylation following ionizing radiation Fulltext Access 11 Pages 2008
Accumulation of nuclear DNA damage or neuron loss: Molecular basis for a new approach to understanding selective neuronal vulnerability in neurodegenerative diseases Fulltext Access 11 Pages 2008
The neurological phenotype of ataxia-telangiectasia: Solving a persistent puzzle Fulltext Access 11 Pages 2008
Direct involvement of the tumor suppressor p53 in nucleotide excision repair Fulltext Access 11 Pages 2008
Widespread distribution of DNA glycosylases removing oxidative DNA lesions in human and rodent brains Fulltext Access 11 Pages 2008
Pol3 is involved in nonhomologous end-joining in Saccharomyces cerevisiae Fulltext Access 11 Pages 2008
Smc5–Smc6 complex suppresses gross chromosomal rearrangements mediated by break-induced replications Fulltext Access 11 Pages 2008
PI3K-Akt signaling regulates basal, but MAP-kinase signaling regulates radiation-induced XRCC1 expression in human tumor cells in vitro Fulltext Access 11 Pages 2008
Reduced efficiency and increased mutagenicity of translesion DNA synthesis across a TT cyclobutane pyrimidine dimer, but not a TT 6-4 photoproduct, in human cells lacking DNA polymerase η Fulltext Access 11 Pages 2008
Replication fork arrest, recombination and the maintenance of ribosomal DNA stability Fulltext Access 11 Pages 2008
A novel silicon complex is as effective as sodium metasilicate in enhancing the collagen-induced inflammatory response of silicon-deprived rats Fulltext Access 11 Pages 2008
Gastrointestinal uptake of trace elements are changed during the course of a common human viral (Coxsackievirus B3) infection in mice Fulltext Access 11 Pages 2008
Development of highly sensitive extractive spectrophotometric determination of nickel(II) in medicinal leaves, soil, industrial effluents and standard alloy samples using pyridoxal-4-phenyl-3-thiosemicarbazone Fulltext Access 11 Pages 2008
Treating paternal drug abuse using Learning Sobriety Together: Effects on adolescents versus children Fulltext Access 11 Pages 2008
Ketamine exposure in adult mice leads to increased cell death in C3H, DBA2 and FVB inbred mouse strains Fulltext Access 11 Pages 2008
Initial reliability and validity studies of the revised Treatment Services Review (TSR-6) Fulltext Access 11 Pages 2008
Inter-informant agreement and prevalence estimates for substance use disorders: Direct interview versus family history method Fulltext Access 11 Pages 2008
Individual differences in adoption of treatment for smoking cessation: Demographic and smoking history characteristics Fulltext Access 11 Pages 2008
The 14-year course of alcoholism in a community sample: Do men and women differ? Fulltext Access 11 Pages 2008