Inducibility of UDP-glucuronosyltransferase 1As by β-naphthoflavone in HepG2 cells Fulltext Access 10 Pages 2006
Molecular pathological analysis for determining the possible mechanism of piperonyl butoxide-induced hepatocarcinogenesis in mice Fulltext Access 10 Pages 2006
Dietary intake estimations of organohalogen contaminants (dioxins, PCB, PBDE and chlorinated pesticides, e.g. DDT) based on Swedish market basket data Fulltext Access 10 Pages 2006
Dietary exposure of Brazilian consumers to dithiocarbamate pesticides—A probabilistic approach Fulltext Access 10 Pages 2006
Dietary sphingolipids suppress a subset of preneoplastic rat liver lesions exhibiting high PTEN, low phospho-Akt and high levels of ceramide species Fulltext Access 10 Pages 2006
Chalcone inhibits the proliferation of human breast cancer cell by blocking cell cycle progression and inducing apoptosis Fulltext Access 10 Pages 2006
Safety studies on epigallocatechin gallate (EGCG) preparations. Part 1: Genotoxicity Fulltext Access 10 Pages 2006
Metabolism-mediated Ochratoxin A genotoxicity in the single-cell gel electrophoresis (Comet) assay Fulltext Access 10 Pages 2006
Characterization of alkyl phenols in cashew (Anacardium occidentale) products and assay of their antioxidant capacity Fulltext Access 10 Pages 2006
Polysaccharide peptides from COV-1 strain of Coriolus versicolor inhibit tolbutamide 4-hydroxylation in the rat in vitro and in vivo Fulltext Access 10 Pages 2006
Dosage effects of curcumin on cell death types in a human osteoblast cell line Fulltext Access 10 Pages 2006
Protection from renal ischemia reperfusion injury by an endothelin-A receptor antagonist BQ-123 in relation to nitric oxide production Fulltext Access 10 Pages 2006
Safety evaluation of phytosterol-esters. Part 9: Results of a European post-launch monitoring programme Fulltext Access 10 Pages 2006
A broad-spectrum organophosphate pesticide O,O-dimethyl O-4-nitrophenyl phosphorothioate (methyl parathion) adversely affects the structure and function of male accessory reproductive organs in the rat Fulltext Access 10 Pages 2006
Effects of polychlorinated biphenyls, hexachlorocyclohexanes, and mercury on human neutrophil apoptosis, actin cytoskelton, and oxidative state Fulltext Access 10 Pages 2006
Comparison of immunnological and genotoxicological parameters in automobile emission inspectors exposed to polycyclic aromatic hydrocarbons Fulltext Access 10 Pages 2006
Combined and individual administration of diethyl phthalate and polychlorinated biphenyls and its toxicity in female Wistar rats Fulltext Access 10 Pages 2006
Pharmacological activity in growth inhibition and apoptosis of cultured human leiomyomal cells of tropical plant Scutellaria barbata D. Don (Lamiaceae) Fulltext Access 10 Pages 2006
DNA damage and apoptosis induction by the pesticide Mancozeb in rat cells: Involvement of the oxidative mechanism Fulltext Access 10 Pages 2006
A mode of action for induction of thyroid gland tumors by Pyrethrins in the rat Fulltext Access 10 Pages 2006
Mechanism of apoptosis induced by a polysaccharide, from the loach Misgurnus anguillicaudatus (MAP) in human hepatocellular carcinoma cells Fulltext Access 10 Pages 2006
Augmented hepatic injury followed by impaired regeneration in metallothionein-I/II knockout mice after treatment with thioacetamide Fulltext Access 10 Pages 2006
A comparative study of the sub-chronic toxic effects of three organic arsenical compounds on the urothelium in F344 rats; gender-based differences in response Fulltext Access 10 Pages 2006
Comparison of the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced CYP1A1 gene expression profile in lymphocytes from mice, rats, and humans: Most potent induction in humans Fulltext Access 10 Pages 2006
Dunkerque City air pollution particulate matter-induced cytotoxicity, oxidative stress and inflammation in human epithelial lung cells (L132) in culture Fulltext Access 10 Pages 2006
Assessment of the phototoxic hazard of some essential oils using modified 3T3 neutral red uptake assay Fulltext Access 10 Pages 2006
Slug species- and population-specific effects on the end points of the Slug Mucosal Irritation test Fulltext Access 10 Pages 2006
Primary rat alveolar epithelial cells for use in biotransformation and toxicity studies Fulltext Access 10 Pages 2006
Organotypic human vaginal-ectocervical tissue model for irritation studies of spermicides, microbicides, and feminine-care products Fulltext Access 10 Pages 2006
In vitro responses of rat alveolar macrophages to particle suspensions and water-soluble components of dust storm PM2.5 Fulltext Access 10 Pages 2006
Consequences of mitochondrial injury induced by pharmaceutical fatty acid oxidation inhibitors is characterized in human and rat liver slices Fulltext Access 10 Pages 2006
150 kDa glycoprotein isolated from Solanum nigrum Linne stimulates caspase-3 activation and reduces inducible nitric oxide production in HCT-116 cells Fulltext Access 10 Pages 2006
Diazene JK-279 induces apoptosis-like cell death in human cervical carcinoma cells Fulltext Access 10 Pages 2006
In vitro investigation of individual and combined cytotoxic effects of ochratoxin A and other selected mycotoxins on renal cells Fulltext Access 10 Pages 2006
S-Adenosylmethionine but not glutathione protects against galactosamine-induced cytotoxicity in rat hepatocyte cultures Fulltext Access 10 Pages 2006
The role of tumor necrosis factor α and the peroxisome proliferator-activated receptor α in modulating the effects of fumonisin in mouse liver Fulltext Access 10 Pages 2006
Effects of the differentiated keratinocyte phenotype on expression levels of CYP1–4 family genes in human skin cells Fulltext Access 10 Pages 2006
Resveratrol induces apoptotic cell death in rat H4IIE hepatoma cells but necrosis in C6 glioma cells Fulltext Access 10 Pages 2006
Anticoagulation and inhibition of nitric oxide synthase influence hepatic hypoxia after monocrotaline exposure Fulltext Access 10 Pages 2006
Catechin prevents tamoxifen-induced oxidative stress and biochemical perturbations in mice Fulltext Access 10 Pages 2006
Localization of cytochrome P450 1A1 in a specific region of hydronephrotic kidney of rat neonates lactationally exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin Fulltext Access 10 Pages 2006
Effects of styrene and styrene oxide on glutathione-related antioxidant enzymes Fulltext Access 10 Pages 2006
Pretreatment with pyridinium oximes improves antidotal therapy against tabun poisoning Fulltext Access 10 Pages 2006
Exposure of pregnant rats to uranium and restraint stress: Effects on postnatal development and behavior of the offspring Fulltext Access 10 Pages 2006
Preventive effect of naringin on lipid peroxides and antioxidants in isoproterenol-induced cardiotoxicity in Wistar rats: Biochemical and histopathological evidences Fulltext Access 10 Pages 2006
Influence of ferulic acid on γ-radiation induced DNA damage, lipid peroxidation and antioxidant status in primary culture of isolated rat hepatocytes Fulltext Access 10 Pages 2006
Effects of fluoroquinolones on HERG channels and on pancreatic β-cell ATP-sensitive K+ channels Fulltext Access 10 Pages 2006
Protection against nonylphenol-induced cell death by DJ-1 in cultured Japanese medaka (Oryzias latipes) cells Fulltext Access 10 Pages 2006
Differentiation of the roles of NO from airway epithelium and inflammatory cells in ozone-induced lung inflammation Fulltext Access 10 Pages 2006
Metabolic basis of ethanol-induced cytotoxicity in recombinant HepG2 cells: Role of nonoxidative metabolism Fulltext Access 10 Pages 2006
Methylmercury-induced toxicity is mediated by enhanced intracellular calcium through activation of phosphatidylcholine-specific phospholipase C Fulltext Access 10 Pages 2006
Altered expression of connexin43 in the inhibition of gap junctional intercellular communication by chlorohydroxyfuranones in WB-F344 rat liver epithelial cells Fulltext Access 10 Pages 2006
Malignant transformation of human colon epithelial cells by benzo[c]phenanthrene dihydrodiolepoxides as well as 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine Fulltext Access 10 Pages 2006
Molecular mechanisms underlying mancozeb-induced inhibition of TNF-alpha production Fulltext Access 10 Pages 2006
Up-regulation of cytosolic phospholipase A2α expression by N,N-diethyldithiocarbamate in PC12 cells; involvement of reactive oxygen species and nitric oxide Fulltext Access 10 Pages 2006
Control of cellular proliferation by modulation of oxidative phosphorylation in human and rodent fast-growing tumor cells Fulltext Access 10 Pages 2006
Activation of peroxisome proliferator-activated receptor-γ (PPARγ) induces cell death through MAPK-dependent mechanism in osteoblastic cells Fulltext Access 10 Pages 2006
CD28 in thymocyte development and peripheral T cell activation in mice exposed to suspended particulate matter Fulltext Access 10 Pages 2006
Bioactivation, protein haptenation, and toxicity of sulfamethoxazole and dapsone in normal human dermal fibroblasts Fulltext Access 10 Pages 2006
Estrogenic compounds inhibit gap junctional intercellular communication in mouse Leydig TM3 cells Fulltext Access 10 Pages 2006
Responses of well-differentiated nasal epithelial cells exposed to particles: Role of the epithelium in airway inflammation Fulltext Access 10 Pages 2006
Energy metabolism and biotransformation as endpoints to pre-screen hepatotoxicity using a liver spheroid model Fulltext Access 10 Pages 2006
Mutual augmentation of the induction of the histamine-forming enzyme, histidine decarboxylase, between alendronate and immuno-stimulants (IL-1, TNF, and LPS), and its prevention by clodronate Fulltext Access 10 Pages 2006
A sea urchin lectin, SUL-1, from the Toxopneustid sea urchin induces DC maturation from human monocyte and drives Th1 polarization in vitro Fulltext Access 10 Pages 2006
Complicating factors in safety testing of drug metabolites: Kinetic differences between generated and preformed metabolites Fulltext Access 10 Pages 2006
p38 mitogen-activated protein kinase mediates IL-8 induction by the ribotoxin deoxynivalenol in human monocytes Fulltext Access 10 Pages 2006
Cystine alters the renal and hepatic disposition of inorganic mercury and plasma thiol status Fulltext Access 10 Pages 2006
Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: A case study with toluene Fulltext Access 10 Pages 2006
Regioselective 2-hydroxylation of 17β-estradiol by rat cytochrome P4501B1 Fulltext Access 10 Pages 2006
Methoxychlor causes mitochondrial dysfunction and oxidative damage in the mouse ovary Fulltext Access 10 Pages 2006
15-Deoxy-Δ12,14-prostaglandin J2 induces renal epithelial cell death through NF-κB-dependent and MAPK-independent mechanism Fulltext Access 10 Pages 2006
Hepatic expression of heme oxygenase-1 and antioxidant response element-mediated genes following administration of ethinyl estradiol to rats Fulltext Access 10 Pages 2006
Regional specificity in deltamethrin induced cytochrome P450 expression in rat brain Fulltext Access 10 Pages 2006
Pathophysiological role of the acute inflammatory response during acetaminophen hepatotoxicity Fulltext Access 10 Pages 2006
Trimethyltin-induced apoptosis is associated with upregulation of inducible nitric oxide synthase and Bax in a hippocampal cell line Fulltext Access 10 Pages 2006
The regulation of cytochrome P450 2E1 during LPS-induced inflammation in the rat Fulltext Access 10 Pages 2006
Co-cultivation of Streptomyces californicus and Stachybotrys chartarum stimulates the production of cytostatic compound(s) with immunotoxic properties Fulltext Access 10 Pages 2006
The coffee diterpene kahweol inhibits tumor necrosis factor-α-induced expression of cell adhesion molecules in human endothelial cells Fulltext Access 10 Pages 2006
Critical role of free cytosolic calcium, but not uncoupling, in mitochondrial permeability transition and cell death induced by diclofenac oxidative metabolites in immortalized human hepatocytes Fulltext Access 10 Pages 2006
Diquat induces renal proximal tubule injury in glutathione reductase-deficient mice Fulltext Access 10 Pages 2006
In vitro screening of 200 pesticides for agonistic activity via mouse peroxisome proliferator-activated receptor (PPAR)α and PPARγ and quantitative analysis of in vivo induction pathway Fulltext Access 10 Pages 2006
Alveolar macrophages have a dual role in a rat model for trimellitic anhydride-induced occupational asthma Fulltext Access 10 Pages 2006
Validation of in vitro cell models used in drug metabolism and transport studies; genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphisms in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS Fulltext Access 10 Pages 2006
T-2 toxin impairs murine immune response to respiratory reovirus and exacerbates viral bronchiolitis Fulltext Access 10 Pages 2006
Differential effects of pyrethroid insecticides on extracellular dopamine in the striatum of freely moving rats Fulltext Access 10 Pages 2006
Triphenyltin impairs a protein kinase A (PKA)-dependent increase of cytosolic Na+ and Ca2+ and PKA-independent increase of cytosolic Ca2+ associated with insulin secretion in hamster pancreatic β-cells Fulltext Access 10 Pages 2006
Pyrethroid pesticide-induced alterations in dopamine transporter function Fulltext Access 10 Pages 2006
Cardiotoxicity of copper-based antineoplastic drugs casiopeinas is related to inhibition of energy metabolism Fulltext Access 10 Pages 2006
Isolation and characterization of two disintegrins inhibiting ADP-induced human platelet aggregation from the venom of Crotalus scutulatus scutulatus (Mohave Rattlesnake) Fulltext Access 10 Pages 2006
Metabonomic evaluation of idiosyncrasy-like liver injury in rats cotreated with ranitidine and lipopolysaccharide Fulltext Access 10 Pages 2006
The cytokine-dependent MUTZ-3 cell line as an in vitro model for the screening of contact sensitizers Fulltext Access 10 Pages 2006
3α-6α-Dihydroxy-7α-fluoro-5β-cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17α-ethynyl-estradiol-induced cholestasis in rats Fulltext Access 10 Pages 2006
The effect of fenbuconazole on cell proliferation and enzyme induction in the liver of female CD1 mice Fulltext Access 10 Pages 2006
Benzo[a]pyrene and glycine N-methyltransferse Interactions: Gene expression profiles of the liver detoxification pathway Fulltext Access 10 Pages 2006
Porphyrinuria in childhood autistic disorder: Implications for environmental toxicity Fulltext Access 10 Pages 2006
4-Hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells Fulltext Access 10 Pages 2006