Photo-chemically induced DNA effects in the comet assay with epidermal cells of SKH-1 mice after a single oral administration of different fluoroquinolones and 8-methoxypsoralen in combination with exposure to UVA Fulltext Access 10 Pages 2006
STW 5 (Iberogast®) and its individual herbal components modulate intestinal electrophysiology of mice Fulltext Access 10 Pages 2006
Antidepressant-like activity of a Kampo (Japanese herbal) medicine, Koso-san (Xiang-Su-San), and its mode of action via the hypothalamic–pituitary–adrenal axis Fulltext Access 10 Pages 2006
Improvement of accessory symptoms of hypertension by TSUMURA Orengedokuto Extract, a four herbal drugs containing Kampo-Medicine Granules for ethical use: A double-blind, placebo-controlled study Fulltext Access 10 Pages 2006
Genotoxic potential of quinolone antimicrobials in the in vitro comet assay and micronucleus test Fulltext Access 10 Pages 2006
Assessment of genotoxicity of 14 chemical agents used in dental practice: Ability to induce chromosome aberrations in Syrian hamster embryo cells Fulltext Access 10 Pages 2006
Clastogenicity, photo-clastogenicity or pseudo-photo-clastogenicity: Genotoxic effects of zinc oxide in the dark, in pre-irradiated or simultaneously irradiated Chinese hamster ovary cells Fulltext Access 10 Pages 2006
The fast halo assay: An improved method to quantify genomic DNA strand breakage at the single-cell level Fulltext Access 10 Pages 2006
Simultaneous measurement of gene expression for hepatotoxicity in thioacetamide-administered rats by DNA microarrays Fulltext Access 10 Pages 2006
Pentachlorophenol treatment in vivo elevates point mutation rate in zebrafish p53 gene Fulltext Access 10 Pages 2006
Region-specific effects of STW 5 (Iberogast®) and its components in gastric fundus, corpus and antrum Fulltext Access 10 Pages 2006
Reliable Comet assay measurements for detecting DNA damage induced by ionising radiation and chemicals Fulltext Access 10 Pages 2006
Molecular analysis of hprt mutations induced by chromium picolinate in CHO AA8 cells Fulltext Access 10 Pages 2006
Biphasic kinetics in the reaction between amino acids or glutathione and the chromium acetate cluster, [Cr3O(OAc)6]+ Fulltext Access 10 Pages 2006
Oral chromium(VI) does not affect the frequency of micronuclei in hematopoietic cells of adult mice and of transplacentally exposed fetuses Fulltext Access 10 Pages 2006
FANCD2 monoubiquitination and activation by hexavalent chromium [Cr(VI)] exposure: Activation is not required for repair of Cr(VI)-induced DSBs Fulltext Access 10 Pages 2006
Determinants of anti-benzo[a]pyrene diol epoxide–DNA adduct formation in lymphomonocytes of the general population Fulltext Access 10 Pages 2006
Characterization of ERCC3 mutations in the Chinese hamster ovary 27-1, UV24 and MMC-2 cell lines Fulltext Access 10 Pages 2006
Seasonal variations of DNA damage in human lymphocytes: Correlation with different environmental variables Fulltext Access 10 Pages 2006
Genetic polymorphisms and possible gene–gene interactions in metabolic and DNA repair genes: Effects on DNA damage Fulltext Access 10 Pages 2006
Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells Fulltext Access 10 Pages 2006
Toxicity assessment of metabolites of fungal biocontrol agents using two different (Artemia salina and Daphnia magna) invertebrate bioassays Fulltext Access 10 Pages 2006
The inhibition of CHO-K1-BH4 cell proliferation and induction of chromosomal aberrations by brevetoxins in vitro Fulltext Access 10 Pages 2006
Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava Fulltext Access 10 Pages 2006
Punica granatum (pomegranate) flower extract possesses potent antioxidant activity and abrogates Fe-NTA induced hepatotoxicity in mice Fulltext Access 10 Pages 2006
Physalis angulata induced G2/M phase arrest in human breast cancer cells Fulltext Access 10 Pages 2006
Sub-chronic (13-week) oral toxicity study in rats with recombinant human lactoferrin produced in the milk of transgenic cows Fulltext Access 10 Pages 2006
The relationship among microsomal enzyme induction, liver weight, and histological change in cynomolgus monkey toxicology studies Fulltext Access 10 Pages 2006
Cytotoxicity of bioactive polymeric fractions from grape cell culture on human hepatocellular carcinoma, murine leukemia and non-cancerous PK15 kidney cells Fulltext Access 10 Pages 2006
Genotoxicity associated to exposure to Prestige oil during autopsies and cleaning of oil-contaminated birds Fulltext Access 10 Pages 2006
Subchronic (13-week) oral toxicity study, preceded by an in utero exposure phase, with arachidonate-enriched triglyceride oil (SUNTGA40S) in rats Fulltext Access 10 Pages 2006
Modulation of immune response following dietary genistein exposure in F0 and F1 generations of C57BL/6 mice: Evidence of thymic regulation Fulltext Access 10 Pages 2006
Induced endoplasmic reticulum (ER) stress and binding of over-expressed ER specific chaperone GRP78/BiP with dimerized epidermal growth factor receptor in mammalian cells exposed to low concentration of N-methyl-N′-nitro-N-nitrosoguanidine Fulltext Access 10 Pages 2006
Isolated perfused and paced guinea pig heart to test for drug-induced changes of the QT interval Fulltext Access 10 Pages 2006
Can optical recordings of membrane potential be used to screen for drug-induced action potential prolongation in single cardiac myocytes? Fulltext Access 10 Pages 2006
A model of orthostatic hypotension in the conscious monkey using lower body negative pressure Fulltext Access 10 Pages 2006
Adaptation of the Folts and electrolytic methods of arterial thrombosis for the study of anti-thrombotic molecules in small animals Fulltext Access 10 Pages 2006
A novel predictive pharmacokinetic/pharmacodynamic model of repolarization prolongation derived from the effects of terfenadine, cisapride and E-4031 in the conscious chronic av node—ablated, His bundle-paced dog Fulltext Access 10 Pages 2006
Current methods used to investigate G protein coupled receptor oligomerisation Fulltext Access 10 Pages 2006
Pharmacokinetic-pharmacodynamic modeling of drug-induced effect on the QT interval in conscious telemetered dogs Fulltext Access 10 Pages 2006
Chronic bile duct obstruction induces changes in plasma and hepatic levels of cytokines and nitric oxide in the rat Fulltext Access 10 Pages 2006
Sanguinarine overcomes P-glycoprotein-mediated multidrug-resistance via induction of apoptosis and oncosis in CEM-VLB 1000 cells Fulltext Access 10 Pages 2006
Herbal melanin modulates tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6) and vascular endothelial growth factor (VEGF) production Fulltext Access 10 Pages 2006
The involvement of non-B DNA structures in gross chromosomal rearrangements Fulltext Access 10 Pages 2006
γH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes Fulltext Access 10 Pages 2006
Caffeine delays replication fork progression and enhances UV-induced homologous recombination in Chinese hamster cell lines Fulltext Access 10 Pages 2006
NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells Fulltext Access 10 Pages 2006
Involvement of DNA mismatch repair in stationary-phase mutagenesis during prolonged starvation of Pseudomonas putida Fulltext Access 10 Pages 2006
Atmnd1-Δ1 is sensitive to gamma-irradiation and defective in meiotic DNA repair Fulltext Access 10 Pages 2006
Targeted gene repair activates Chk1 and Chk2 and stalls replication in corrected cells Fulltext Access 10 Pages 2006
Impaired elimination of DNA double-strand break-containing lymphocytes in ataxia telangiectasia and Nijmegen breakage syndrome Fulltext Access 10 Pages 2006
A distinct TthMutY bifunctional glycosylase that hydrolyzes not only adenine but also thymine opposite 8-oxoguanine in the hyperthermophilic bacterium, Thermus thermophilus Fulltext Access 10 Pages 2006
Rad33, a new factor involved in nucleotide excision repair in Saccharomyces cerevisae Fulltext Access 10 Pages 2006
Perspectives on the formation of radiation-induced exchange aberrations Fulltext Access 10 Pages 2006
The nuclear accumulation of the Fanconi anemia protein FANCE depends on FANCC Fulltext Access 10 Pages 2006
Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: New insights and new questions Fulltext Access 10 Pages 2006
Modeling oncogenic translocations: Distinct roles for double-strand break repair pathways in translocation formation in mammalian cells Fulltext Access 10 Pages 2006
Iron chelators reduce chromosomal breaks in ataxia-telangiectasia cells Fulltext Access 10 Pages 2006
A novel Rad18 function involved in protection of the vertebrate genome after exposure to camptothecin Fulltext Access 10 Pages 2006
Trace element status in Saudi patients with established atherosclerosis Fulltext Access 10 Pages 2006
Biomonitoring of 37 trace elements in blood samples from inhabitants of northern Germany by ICP–MS Fulltext Access 10 Pages 2006
Adaptive mutations in Salmonella typhimurium phenotypic of purR super-repression Fulltext Access 10 Pages 2006
Identification of somatic and germline mitochondrial DNA sequence variants in prostate cancer patients Fulltext Access 10 Pages 2006
High frequency induction of mitotic recombination by ionizing radiation in Mlh1 null mouse cells Fulltext Access 10 Pages 2006
Hemoglobin and hemin induce DNA damage in human colon tumor cells HT29 clone 19A and in primary human colonocytes Fulltext Access 10 Pages 2006
Inducibility of nuclear Rad51 foci after DNA damage distinguishes all Fanconi anemia complementation groups from D1/BRCA2 Fulltext Access 10 Pages 2006
The effects of exposure to different clastogens on the pattern of chromosomal aberrations detected by FISH whole chromosome painting in occupationally exposed individuals Fulltext Access 10 Pages 2006
2-Dodecylcyclobutanone, a radiolytic product of palmitic acid, is genotoxic in primary human colon cells and in cells from preneoplastic lesions Fulltext Access 10 Pages 2006
Immunofluorescent detection of 8-oxoguanine DNA lesions in liver cells from aging OXYS rats, a strain prone to overproduction of free radicals Fulltext Access 10 Pages 2006
Genetic damage in cultured human keratinocytes stressed by long-term exposure to areca nut extracts Fulltext Access 10 Pages 2006
Molecular analysis of the RET and NTRK1 gene rearrangements in papillary thyroid carcinoma in the Polish population Fulltext Access 10 Pages 2006
Origins of human mitochondrial point mutations as DNA polymerase γ-mediated errors Fulltext Access 10 Pages 2006
Sulforaphane increases the efficacy of doxorubicin in mouse fibroblasts characterized by p53 mutations Fulltext Access 10 Pages 2006
Aberrant and multiaberrant (rogue) cells in peripheral lymphocytes of Hodgkin's lymphoma patients after chemotherapy Fulltext Access 10 Pages 2006
Analysis of UV-induced mutation spectra in Escherichia coli by DNA polymerase η from Arabidopsis thaliana Fulltext Access 10 Pages 2006
Chinese hamster cell mutant, V-C8, a model for analysis of Brca2 function Fulltext Access 10 Pages 2006
Does loss of heterozygosity in critical genome regions predict a local relapse in patients after laryngectomy? Fulltext Access 10 Pages 2006
Acute exposure to UVB has a more profound effect on plant genome stability than chronic exposure Fulltext Access 10 Pages 2006
p21 controls patterning but not homologous recombination in RPE development Fulltext Access 10 Pages 2006
Telomerase-immortalized human fibroblasts retain UV-induced mutagenesis and p53-mediated DNA damage responses Fulltext Access 10 Pages 2006
Host cell reactivation of plasmids containing oxidative DNA lesions is defective in Cockayne syndrome but normal in UV-sensitive syndrome fibroblasts Fulltext Access 10 Pages 2006
Contribution of Msh2 and Msh6 subunits to the asymmetric ATPase and DNA mismatch binding activities of Saccharomyces cerevisiae Msh2–Msh6 mismatch repair protein Fulltext Access 10 Pages 2006