In vitro systems toxicology-based assessment of the potential modified risk tobacco product CHTP 1.2 for vascular inflammation- and cytotoxicity-associated mechanisms promoting adhesion of monocytic cells to human coronary arterial endothelial cells

Article ID	Journal	Published Year	Pages	File Type
8546364	Food and Chemical Toxicology	2018	88 Pages	PDF

Keywords

IPN ICAM-1 GSH HCAEC BIF FDR VIP SRP NPA FCS 7-AAD 7-aminoactinomycin D HPHC biological impact factor MRTP CFA NF-κB MM6 CSt LC/ESI-MS/MS PCA ROS THs Atherosclerosis CPR Cell stress cardiovascular disease Principal component analysis tumor necrosis factor-alpha Cell proliferation Cigarette smoke CVD fetal calf serum Cell fate Human coronary artery endothelial cell Endothelial cell Tobacco heating system Cigarette DEG TNF-α Nuclear factor-kappa B Modified risk tobacco product Harmful and potentially harmful constituent principal component Intercellular adhesion molecule 1 Mono Mac 6 Monocyte tra false discovery rate Adhesion Differentially expressed gene Liquid chromatography electrospray ionization tandem mass spectrometry Vehicle control glutathion Reactive oxygen species

Related Topics

Life Sciences Agricultural and Biological Sciences Food Science

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In vitro systems toxicology-based assessment of the potential modified risk tobacco product CHTP 1.2 for vascular inflammation- and cytotoxicity-associated mechanisms promoting adhesion of monocytic cells to human coronary arterial endothelial cells

Authors

Carine Poussin, Alexandra Laurent, Athanasios Kondylis, Diego Marescotti, Marco van der Toorn, Emmanuel Guedj, Didier Goedertier, Stefano Acali, Claudius Pak, Rémi Dulize, Karine Baumer, Dariusz Peric, Elodie Maluenda, David Bornand,