Double-stranded RNA transcribed from vector-based oligodeoxynucleotide acts as transcription factor decoy Fulltext Access 6 Pages 2015
Peptide inhibitors of human HMG-CoA reductase as potential hypocholesterolemia agents Fulltext Access 6 Pages 2015
C-terminal domain of CagX is responsible for its interaction with CagT protein of Helicobacter pylori type IV secretion system Fulltext Access 6 Pages 2015
Secondhand smoke exposure-induced nucleocytoplasmic shuttling of HMGB1 in a rat premature skin aging model Fulltext Access 6 Pages 2015
Inhibition of MEK/ERK activation attenuates autophagy and potentiates pemetrexed-induced activity against HepG2 hepatocellular carcinoma cells Fulltext Access 6 Pages 2015
QCM-4, a 5-HT3 receptor antagonist ameliorates plasma HPA axis hyperactivity, leptin resistance and brain oxidative stress in depression and anxiety-like behavior in obese mice Fulltext Access 6 Pages 2015
HL-217, a new topical anti-angiogenic agent, inhibits retinal vascular leakage and pathogenic subretinal neovascularization in Vldlrâ/â mice Fulltext Access 6 Pages 2015
Five eIF4E isoforms from Arabidopsis thaliana are characterized by distinct features of cap analogs binding Fulltext Access 6 Pages 2015
Improvement of insulin signaling in myoblast cells by an addition of SKIP-binding peptide within Pak1 kinase domain Fulltext Access 6 Pages 2015
Crystal structure of 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase, an NAD+-dependent dismutase from Mesorhizobium loti Fulltext Access 6 Pages 2015
Impact of cadmium, cobalt and nickel on sequence-specific DNA binding of p63 and p73 in vitro and in cells Fulltext Access 6 Pages 2015
Mitochondrial division inhibitor 1 (mdivi-1) enhances death receptor-mediated apoptosis in human ovarian cancer cells Fulltext Access 6 Pages 2015
RNA polymerase III control elements are required for trans-activation by the murine retroviral long terminal repeat sequences Fulltext Access 6 Pages 2015
Evaluation of the reliability of the maximum entropy method for reconstructing 3D and 4D NOESY-type NMR spectra of proteins Fulltext Access 6 Pages 2015
Synthetic ceramide analogues increase amyloid-β 42 production by modulating γ-secretase activity Fulltext Access 6 Pages 2015
Proteome screening of pleural effusions identifies IL1A as a diagnostic biomarker for non-small cell lung cancer Fulltext Access 6 Pages 2015
MiRNA-125a-5p inhibits glioblastoma cell proliferation and promotes cell differentiation by targeting TAZ Fulltext Access 6 Pages 2015
Chronic effects of neuroendocrine regulatory peptide (NERP-1 and -2) on insulin secretion and gene expression in pancreatic β-cells Fulltext Access 6 Pages 2015
Involvement of the G-protein-coupled receptor 4 in RANKL expression by osteoblasts in an acidic environment Fulltext Access 6 Pages 2015
Crystal structure and function of an unusual dimeric Hsp20.1 provide insight into the thermal protection mechanism of small heat shock proteins Fulltext Access 6 Pages 2015
Steady-state and time-resolved Thioflavin-T fluorescence can report on morphological differences in amyloid fibrils formed by Aβ(1-40) and Aβ(1-42) Fulltext Access 6 Pages 2015
NPTX1 is a novel epigenetic regulation gene and associated with prognosis in lung cancer Fulltext Access 6 Pages 2015
PPARγ and MyoD are differentially regulated by myostatin in adipose-derived stem cells and muscle satellite cells Fulltext Access 6 Pages 2015
Crystal structure of dehydratase component HadAB complex of mycobacterial FAS-II pathway Fulltext Access 6 Pages 2015
Thermodynamic parameters for binding of some halogenated inhibitors of human protein kinase CK2 Fulltext Access 6 Pages 2015
The use of SMALPs as a novel membrane protein scaffold for structure study by negative stain electron microscopy Fulltext Access 6 Pages 2015
Phospholipases a2 from Viperidae snakes: Differences in membranotropic activity between enzymatically active toxin and its inactive isoforms Fulltext Access 6 Pages 2015
Isolation and characterization of 2â²-F-RNA aptamers against whole HIV-1 subtype C envelope pseudovirus Fulltext Access 6 Pages 2015
Autocrine pathways involving S100A8 and/or S100A9 that are postulated to regulate the immunological functions of macrophages in rats Fulltext Access 6 Pages 2015
Three-dimensional human arterial wall models for in vitro permeability assessment of drug and nanocarriers Fulltext Access 6 Pages 2015
Adiponectin signals through Adiponectin Receptor 1 to reverse imatinib resistance in K562 human chronic myeloid leukemia cells Fulltext Access 6 Pages 2015
miR-203 inhibits melanoma invasive and proliferative abilities by targeting the polycomb group gene BMI1 Fulltext Access 6 Pages 2015
Prostaglandin D2 synthase related to estrogen in the female reproductive tract Fulltext Access 6 Pages 2015
DEAD-box RNA helicase DDX3X inhibits DENV replication via regulating type one interferon pathway Fulltext Access 6 Pages 2015
Disrupted cell cycle arrest and reduced proliferation in corneal fibroblasts from GCD2 patients: A potential role for altered autophagy flux Fulltext Access 6 Pages 2015
Adipocyte membrane glycerol permeability is involved in the anti-adipogenic effect of conjugated linoleic acid Fulltext Access 6 Pages 2015
FOXD1 promotes breast cancer proliferation and chemotherapeutic drug resistance by targeting p27 Fulltext Access 6 Pages 2015
Visualization of the human CD4+ T-cell response in humanized HLA-DR4-expressing NOD/Shi-scid/γcnull (NOG) mice by retrogenic expression of the human TCR gene Fulltext Access 6 Pages 2015
Characterization of the minimal length of functional SecA in Escherichia coli Fulltext Access 6 Pages 2015
The pH-sensitive structure of the C-terminal domain of voltage-gated proton channel and the thermodynamic characteristics of Zn2+ binding to this domain Fulltext Access 6 Pages 2015
Metformin enhances the anti-adipogenic effects of atorvastatin via modulation of STAT3 and TGF-β/Smad3 signaling Fulltext Access 6 Pages 2015
Prostaglandin potentiates 5-HT responses in stomach and ileum innervating visceral afferent sensory neurons Fulltext Access 6 Pages 2015
PXD101 significantly improves nuclear reprogramming and the in vitro developmental competence of porcine SCNT embryos Fulltext Access 6 Pages 2015
Inhibition of protein kinase C affects on mode of synaptic vesicle exocytosis due to cholesterol depletion Fulltext Access 6 Pages 2015
DPP IV inhibitor suppresses STZ-induced islets injury dependent on activation of the IGFR/Akt/mTOR signaling pathways by GLP-1 in monkeys Fulltext Access 6 Pages 2015
Co-expression of human agouti-related protein enhances expression and stability of human melanocortin-4 receptor Fulltext Access 6 Pages 2015
TBX5 loss-of-function mutation contributes to familial dilated cardiomyopathy Fulltext Access 6 Pages 2015
Multiple lysines combined in HIV-1 Vif determines the responsiveness to CBF-β Fulltext Access 6 Pages 2015
EpCAM is up-regulated by EGF via ERK1/2 signaling and suppresses human epithelial ovarian cancer cell migration Fulltext Access 6 Pages 2015
The glucosylceramide synthase inhibitor PDMP sensitizes pancreatic cancer cells to MEK/ERK inhibitor AZD-6244 Fulltext Access 6 Pages 2015
Triptolide inhibits proliferation of Epstein-Barr virus-positive B lymphocytes by down-regulating expression of a viral protein LMP1 Fulltext Access 6 Pages 2015
microRNA-218 inhibits prostate cancer cell growth and promotes apoptosis by repressing TPD52 expression Fulltext Access 6 Pages 2015
A cyclic peptide accelerates the loading of peptide antigens in major histocompatibility complex class II molecules Fulltext Access 6 Pages 2015
Effective internalization of U251-MG-secreted exosomes into cancer cells and characterization of their lipid components Fulltext Access 6 Pages 2015
The MUC1 oncomucin regulates pancreatic cancer cell biological properties and chemoresistance. Implication of p42-44 MAPK, Akt, Bcl-2 and MMP13 pathways Fulltext Access 6 Pages 2015
Glucagon directly interacts with vagal afferent nodose ganglion neurons to induce Ca2+ signaling via glucagon receptors Fulltext Access 6 Pages 2015
Trps1 deficiency inhibits the morphogenesis of secondary hair follicles via decreased Noggin expression Fulltext Access 6 Pages 2015
Structural and biochemical characterization of MCAT from photosynthetic microorganism Synechocystis sp. PCC 6803 reveal its stepwise catalytic mechanism Fulltext Access 6 Pages 2015
Characterization of a novel domain 'GATE' in the ABC protein DrrA and its role in drug efflux by the DrrAB complex Fulltext Access 6 Pages 2015
1α,25 dihydroxi-vitamin D3 modulates CDK4 and CDK6 expression and localization Fulltext Access 6 Pages 2015
Toxoplasma gondii: Biochemical and biophysical characterization of recombinant soluble dense granule proteins GRA2 and GRA6 Fulltext Access 6 Pages 2015
Quadruplex forming promoter region of c-myc oncogene as a potential target for a telomerase inhibitory plant alkaloid, chelerythrine Fulltext Access 6 Pages 2015
Transcriptome sequencing and differential gene expression analysis in Viola yedoensis Makino (Fam. Violaceae) responsive to cadmium (Cd) pollution Fulltext Access 6 Pages 2015
Cardiomyocyte lipotoxicity is mediated by Il-6 and causes down-regulation of PPARs Fulltext Access 6 Pages 2015
Computational analysis of the extracellular domain of the Ca2+-sensing receptor: An alternate model for the Ca2+ sensing region Fulltext Access 6 Pages 2015
Probing the gel to liquid-crystalline phase transition and relevant conformation changes in liposomes by 13C magic-angle spinning NMR spectroscopy Fulltext Access 6 Pages 2015
An efficient and cost-effective approach to kahalalide F N-terminal modifications using a nuisance algal bloom of Bryopsis pennata Fulltext Access 6 Pages 2015
The repressor Rgt1 and the cAMP-dependent protein kinases control the expression of the SUC2 gene in Saccharomyces cerevisiae Fulltext Access 6 Pages 2015
Transgene-derived overexpression of miR-17-92 in CD8+ T-cells confers enhanced cytotoxic activity Fulltext Access 6 Pages 2015
Gemcitabine-induced CXCL8 expression counteracts its actions by inducing tumor neovascularization Fulltext Access 6 Pages 2015
PSMB4 promotes multiple myeloma cell growth by activating NF-κB-miR-21 signaling Fulltext Access 6 Pages 2015
MicroRNAs let-7b/i suppress human glioma cell invasion and migration by targeting IKBKE directly Fulltext Access 6 Pages 2015
Disrupted light-dark cycle abolishes circadian expression of peripheral clock genes without inducing behavioral arrhythmicity in mice Fulltext Access 6 Pages 2015
Low expression level of glnA1 accounts for absence of cell wall associated poly-l-glutamate/glutamine in Mycobacterium smegmatis Fulltext Access 6 Pages 2015
Downregulation of FOXP3 inhibits invasion and immune escape in cholangiocarcinoma Fulltext Access 6 Pages 2015
miR-1271 promotes non-small-cell lung cancer cell proliferation and invasion via targeting HOXA5 Fulltext Access 6 Pages 2015
Structure analysis of Bacillus cereus MepR-like transcription regulator, BC0657, in complex with pseudo-ligand molecules Fulltext Access 6 Pages 2015
Isoaspartate, carbamoyl phosphate synthase-1, and carbonic anhydrase-III as biomarkers of liver injury Fulltext Access 6 Pages 2015
Effects of culturing media on hepatocytes differentiation using Volvox sphere as co-culturing vehicle Fulltext Access 6 Pages 2015
Flavone inhibits nitric oxide synthase (NOS) activity, nitric oxide production and protein S-nitrosylation in breast cancer cells Fulltext Access 6 Pages 2015
Involvement of the histamine H1 receptor in the regulation of sympathetic nerve activity Fulltext Access 6 Pages 2015
13C NMR based profiling unveils different α-ketoglutarate pools involved into glutamate and lysine synthesis in the milk yeast Kluyveromyces lactis Fulltext Access 6 Pages 2015
A cooled CCD camera-based protocol provides an effective solution for in vitro monitoring of luciferase Fulltext Access 6 Pages 2015
Retinoic acid inhibits histone methyltransferase Whsc1 during palatogenesis Fulltext Access 6 Pages 2015
Physical interaction between MPP8 and PRC1 complex and its implication for regulation of spermatogenesis Fulltext Access 6 Pages 2015
Differential apoptotic effect and metabolism of N-acetylsphingosine and N-hexanoylsphingosine in CHP-100 human neurotumor cells Fulltext Access 6 Pages 2015
Rac1 modulates cardiomyocyte adhesion during mouse embryonic development Fulltext Access 6 Pages 2015
The perivascular phenotype and behaviors of dedifferentiated cells derived from human mature adipocytes Fulltext Access 6 Pages 2015
General order parameter based correlation analysis of protein backbone motions between experimental NMR relaxation measurements and molecular dynamics simulations Fulltext Access 6 Pages 2015
Inhibition of Mer and Axl receptor tyrosine kinases leads to increased apoptosis and improved chemosensitivity in human neuroblastoma Fulltext Access 6 Pages 2015
Pam2 lipopeptides systemically increase myeloid-derived suppressor cells through TLR2 signaling Fulltext Access 6 Pages 2015