An intrinsically disordered domain in Polaribacter irgensii KOPRI 22228 CspB confers extraordinary freeze-tolerance Fulltext Access 7 Pages 2018
Prohibitin-2 is a novel regulator of p21WAF1/CIP1 induced by depletion of γ-glutamylcyclotransferase Fulltext Access 7 Pages 2018
Septin4 as a novel binding partner of PARP1 contributes to oxidative stress induced human umbilical vein endothelial cells injure Fulltext Access 7 Pages 2018
LncRNA GAS5 regulates ischemic stroke as a competing endogenous RNA for miR-137 to regulate the Notch1 signaling pathway Fulltext Access 7 Pages 2018
Structural insights into the impact of two holoprosencephaly-related mutations on human TGIF1 homeodomain Fulltext Access 7 Pages 2018
Truncated CD200 stimulates tumor immunity leading to fewer lung metastases in a novel Wistar rat metastasis model Fulltext Access 7 Pages 2018
Analysis of the interactions between GMF and Arp2/3 complex in two binding sites by molecular dynamics simulation Fulltext Access 7 Pages 2018
Eupatilin, an activator of PPARα, inhibits the development of oxazolone-induced atopic dermatitis symptoms in Balb/c mice Fulltext Access 7 Pages 2018
BMI1 activates WNT signaling in colon cancer by negatively regulating the WNT antagonist IDAX Fulltext Access 7 Pages 2018
The Nem1-Spo7 protein phosphatase complex is required for efficient mitophagy in yeast Fulltext Access 7 Pages 2018
Characterization of the promoter region of bovine SIX4: Roles of E-box and MyoD in the regulation of basal transcription Fulltext Access 7 Pages 2018
Acidification induces OGR1/Ca2+/calpain signaling in gingival fibroblasts Fulltext Access 7 Pages 2018
B cell activation in the cecal patches during the development of an experimental colitis model Fulltext Access 7 Pages 2018
MicroRNA-425 facilitates pathogenic Th17 cell differentiation by targeting forkhead box O1 (Foxo1) and is associated with inflammatory bowel disease Fulltext Access 7 Pages 2018
Loss of zebrafish Smyd1a interferes with myofibrillar integrity without triggering the misfolded myosin response Fulltext Access 7 Pages 2018
Heterogeneity of autophagic status in pancreatic β cells under metabolic stress Fulltext Access 7 Pages 2018
Downregulation of exocyst Sec10 accelerates kidney tubule cell recovery through enhanced cell migration Fulltext Access 7 Pages 2018
Functional characterization of lethal P-loop mutations in Tetrahymena outer arm dynein (Dyh3p) Fulltext Access 7 Pages 2018
Isolation and characterization of the betalain biosynthesis gene involved in hypocotyl pigmentation of the allotetraploid Chenopodium quinoa Fulltext Access 7 Pages 2018
Role of the mRNA export factor Sus1 in oxidative stress tolerance in Candida albicans Fulltext Access 7 Pages 2018
The histone demethylase PHF8 promotes adult acute lymphoblastic leukemia through interaction with the MEK/ERK signaling pathway Fulltext Access 7 Pages 2018
IL-1R2 deficiency suppresses dextran sodium sulfate-induced colitis in mice via regulation of microbiota Fulltext Access 7 Pages 2018
Bromodomain-containing protein 7 deficiency augments atherosclerotic lesions in ApoEâ/â mice Fulltext Access 7 Pages 2018
A novel cold-regulated gene from Phlox subulata, PsCor413im1, enhances low temperature tolerance in Arabidopsis Fulltext Access 7 Pages 2018
MTD-like motif of a BH3-only protein, BNIP1, induces necrosis accompanied by an intracellular calcium spike Fulltext Access 7 Pages 2018
Structural insight into the substrate specificity of acyl-CoA oxidase1 from Yarrowia lipolytica for short-chain dicarboxylyl-CoAs Fulltext Access 7 Pages 2018
Long noncoding RNA SNHG15 promotes human breast cancer proliferation, migration and invasion by sponging miR-211-3p Fulltext Access 7 Pages 2018
Effects of the RNA-binding protein, KSRP, on innate immune response against Helicobacter pylori infection in mice Fulltext Access 7 Pages 2018
Hypoxia-induced activation of Twist/miR-214/E-cadherin axis promotes renal tubular epithelial cell mesenchymal transition and renal fibrosis Fulltext Access 7 Pages 2018
Genome-wide identification of chromatin-enriched RNA reveals that unspliced dentin matrix protein-1 mRNA regulates cell proliferation in squamous cell carcinoma Fulltext Access 7 Pages 2018
DANFIN functions as an inhibitor of transcription factor NF-κB and potentiates the antitumor effect of bortezomib in multiple myeloma Fulltext Access 7 Pages 2018
Anosmin-1 is essential for neural crest and cranial placodes formation in Xenopus Fulltext Access 7 Pages 2018
S-adenosylmethionine reduces the inhibitory effect of Aβ on BDNF expression through decreasing methylation level of BDNF exon ⠣ in rats Fulltext Access 7 Pages 2018
FGFR1 is essential for N-acetyl-seryl-aspartyl-lysyl-proline regulation of mitochondrial dynamics by upregulating microRNA let-7b-5p Fulltext Access 7 Pages 2018
Trek2a regulates gnrh3 expression under control of melatonin receptor Mt1 and α2-adrenoceptor Fulltext Access 7 Pages 2018
Measurement of enzymatic and motile activities of Arabidopsis myosins by using Arabidopsis actins Fulltext Access 7 Pages 2018
Inhibition of Notch signaling pathway using γ-secretase inhibitor delivered by a low dose of Triton-X100 in cultured oral cancer cells Fulltext Access 7 Pages 2018
PARIS reprograms glucose metabolism by HIF-1α induction in dopaminergic neurodegeneration Fulltext Access 7 Pages 2018
LncRNA MALAT1 regulates oxLDL-induced CD36 expression via activating β-catenin Fulltext Access 7 Pages 2018
Hydrogen postconditioning promotes survival of rat retinal ganglion cells against ischemia/reperfusion injury through the PI3K/Akt pathway Fulltext Access 7 Pages 2018
Hepatocellular carcinoma-associated depletion of the netrin-1 receptor Uncoordinated Phenotype-5A (UNC5A) skews the hepatic unfolded protein response towards prosurvival outcomes Fulltext Access 7 Pages 2018
1α,25-dihydroxyvitamin D3 mitigates cancer cell mediated mitochondrial dysfunction in human skeletal muscle cells Fulltext Access 7 Pages 2018
An enhanced anti-tumor effect of apoptin-cecropin B on human hepatoma cells by using bacterial magnetic particle gene delivery system Fulltext Access 7 Pages 2018
Long noncoding RNA SNHG7 promotes the progression and growth of glioblastoma via inhibition of miR-5095 Fulltext Access 7 Pages 2018
Overexpression of Larp4B downregulates dMyc and reduces cell and organ sizes in Drosophila Fulltext Access 7 Pages 2018
Downregulated CDKN1C/p57kip2 drives tumorigenesis and associates with poor overall survival in breast cancer Fulltext Access 7 Pages 2018
Overexpression of germin-like protein GmGLP10 enhances resistance to Sclerotinia sclerotiorum in transgenic tobacco Fulltext Access 7 Pages 2018
RIP2 enhances cell survival by activation of NF-ĸB in triple negative breast cancer cells Fulltext Access 7 Pages 2018
High expression of microRNA-4295 contributes to cell proliferation and invasion of pancreatic ductal adenocarcinoma by the down-regulation of Glypican-5 Fulltext Access 7 Pages 2018
Caspase independent cleavages of TDP-43 generates 35kD fragment that cause apoptosis of breast cancer cells Fulltext Access 7 Pages 2018
Liver-specific deletion of TSHR inhibits hepatic lipid accumulation in mice Fulltext Access 7 Pages 2018
GPR182 is a novel marker for sinusoidal endothelial differentiation with distinct GPCR signaling activity in vitro Fulltext Access 7 Pages 2018
Comparison of two hyoscyamine 6β-hydroxylases in engineering scopolamine biosynthesis in root cultures of Scopolia lurida Fulltext Access 7 Pages 2018
Redox exchange of the disulfides of human two-domain CD4 regulates the conformational dynamics of each domain, providing insight into its mechanisms of control Fulltext Access 7 Pages 2018
Cytoplasmic p53 contributes to the removal of uracils misincorporated by HIV-1 reverse transcriptase Fulltext Access 7 Pages 2018
Transcriptional information revealed differentially expressed circular RNAs in facet joint osteoarthritis Fulltext Access 7 Pages 2018
Ribosome biogenesis protein Urb2 regulates hematopoietic stem cells development via P53 pathway in zebrafish Fulltext Access 7 Pages 2018
Combination effects of alogliptin and pioglitazone on steatosis and hepatic fibrosis formation in a mouse model of non-alcoholic steatohepatitis Fulltext Access 7 Pages 2018
N-terminus plus linker domain of Mg-chelatase D subunit is essential for Mg-chelatase activity in Oryza sativa Fulltext Access 7 Pages 2018
NEK3-mediated SNAP29 phosphorylation modulates its membrane association and SNARE fusion dependent processes Fulltext Access 7 Pages 2018
Construction of EMSC-islet co-localizing composites for xenogeneic porcine islet transplantation Fulltext Access 7 Pages 2018
Long noncoding RNA BDNF-AS is a potential biomarker and regulates cancer development in human retinoblastoma Fulltext Access 7 Pages 2018
Notch1 regulates PTEN expression to exacerbate renal tubulointerstitial fibrosis in diabetic nephropathy by inhibiting autophagy via interactions with Hes1 Fulltext Access 7 Pages 2018
Adenosine receptors enhance the ATP-induced odontoblastic differentiation of human dental pulp cells Fulltext Access 7 Pages 2018
Adrenergic receptor-mediated activation of FGF-21-adiponectin axis exerts atheroprotective effects in brown adipose tissue-transplanted apoEâ/â mice Fulltext Access 7 Pages 2018
Effect of tamoxifen on the sphingolipid biosynthetic pathway in the different intraerythrocytic stages of the apicomplexa Plasmodium falciparum Fulltext Access 7 Pages 2018
Tumor-targeting Salmonella typhimurium A1-R is a highly effective general therapeutic for undifferentiated soft tissue sarcoma patient-derived orthotopic xenograft nude-mouse models Fulltext Access 7 Pages 2018
Regulation of Tak1 alternative splicing by splice-switching oligonucleotides Fulltext Access 7 Pages 2018
Apigetrin inhibits gastric cancer progression through inducing apoptosis and regulating ROS-modulated STAT3/JAK2 pathway Fulltext Access 7 Pages 2018
CBFA2T2 is required for BMP-2-induced osteogenic differentiation of mesenchymal stem cells Fulltext Access 7 Pages 2018
CaMKII-mediated phosphorylation of RyR2 plays a crucial role in aberrant Ca2+ release as an arrhythmogenic substrate in cardiac troponin T-related familial hypertrophic cardiomyopathy Fulltext Access 7 Pages 2018
Long non-coding RNA MEG3 silencing protects against light-induced retinal degeneration Fulltext Access 7 Pages 2018
Hepatitis C virus regulates proprotein convertase subtilisin/kexin type 9 promoter activity Fulltext Access 7 Pages 2018
MicroRNA-29a mitigation of toll-like receptor 2 and 4 signaling and alleviation of obstructive jaundice-induced fibrosis in mice Fulltext Access 7 Pages 2018
Re-engineering and evaluation of anti-DNA autoantibody 3E10 for therapeutic applications Fulltext Access 7 Pages 2018
Immunomodulatory effects of polysaccharide fraction isolated from Fagopyrum esculentum on innate immune system Fulltext Access 7 Pages 2018
Optimal route of diphtheria toxin administration to eliminate native nephron progenitor cells in vivo for kidney regeneration Fulltext Access 7 Pages 2018
Biophysical and biochemical characterization of Rv3405c, a tetracycline repressor protein from Mycobacterium tuberculosis Fulltext Access 7 Pages 2018
Autophagy activated by SIRT6 regulates Aβ induced inflammatory response in RPEs Fulltext Access 7 Pages 2018
Overexpression of histone methyltransferase NSD in Drosophila induces apoptotic cell death via the Jun-N-terminal kinase pathway Fulltext Access 7 Pages 2018
ZSCAN4 is negatively regulated by the ubiquitin-proteasome system and the E3 ubiquitin ligase RNF20 Fulltext Access 7 Pages 2018
Both the PH domain and N-terminal region of oxysterol-binding protein related protein 8S are required for localization to PM-ER contact sites Fulltext Access 7 Pages 2018
Increased circular RNA hsa_circ_0012673 acts as a sponge of miR-22 to promote lung adenocarcinoma proliferation Fulltext Access 7 Pages 2018
Epigallocatechin-3-gallate attenuates acute and chronic psoriatic itch in mice: Involvement of antioxidant, anti-inflammatory effects and suppression of ERK and Akt signaling pathways Fulltext Access 7 Pages 2018
Synergistic tumoricidal effect of combined hPD-L1 vaccine and HER2 gene vaccine Fulltext Access 7 Pages 2018
Decrease in the cytosolic NADP+-dependent isocitrate dehydrogenase activity through porcine sperm capacitation Fulltext Access 7 Pages 2018
Up-regulation of MSH6 is associated with temozolomide resistance in human glioblastoma Fulltext Access 7 Pages 2018
Cellular toxicity driven by high-dose vitamin C on normal and cancer stem cells Fulltext Access 7 Pages 2018
DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1P29S mutation Fulltext Access 7 Pages 2018
GAS5 silencing protects against hypoxia/ischemia-induced neonatal brain injury Fulltext Access 7 Pages 2018
Antibiotic ivermectin selectively induces apoptosis in chronic myeloid leukemia through inducing mitochondrial dysfunction and oxidative stress Fulltext Access 7 Pages 2018