The orphan G protein-coupled receptor 25 (GPR25) is activated by Apelin and Apela in non-mammalian vertebrates Fulltext Access 7 Pages 2018
3D culture system containing gellan gum restores oncogene dependence in ROS1 rearrangements non-small cell lung cancer Fulltext Access 7 Pages 2018
Apolipoprotein M promotes proliferation and invasion in non-small cell lung cancers via upregulating S1PR1 and activating the ERK1/2 and PI3K/AKT signaling pathways Fulltext Access 7 Pages 2018
miR-485-5p suppresses breast cancer progression and chemosensitivity by targeting survivin Fulltext Access 7 Pages 2018
MiR-141-3p is upregulated in esophageal squamous cell carcinoma and targets pleckstrin homology domain leucine-rich repeat protein phosphatase-2, a negative regulator of the PI3K/AKT pathway Fulltext Access 7 Pages 2018
Tracing the dynamic expression of the Nfκb2 gene during inflammatory processes by in vivo bioluminescence imaging in transgenic mice Fulltext Access 7 Pages 2018
MiR-26a-5p potentiates metastasis of human lung cancer cells by regulating ITGβ8- JAK2/STAT3 axis Fulltext Access 7 Pages 2018
GSK126 alleviates the obesity phenotype by promoting the differentiation of thermogenic beige adipocytes in diet-induced obese mice Fulltext Access 7 Pages 2018
Cystathionine gamma lyase-H2S contributes to osteoclastogenesis during bone remodeling induced by mechanical loading Fulltext Access 7 Pages 2018
The roles of two O-donor ligands in the Fe2+-binding and H2O2-sensing by the Fe2+-dependent H2O2 sensor PerR Fulltext Access 7 Pages 2018
Reduced adiposity by compensatory WAT browning upon iBAT removal in mice Fulltext Access 7 Pages 2018
Roles of 14-3-3β and γ in regulation of the glucocorticoid receptor transcriptional activation and hepatic gluconeogenesis Fulltext Access 7 Pages 2018
PIM1-catalyzed CBX8 phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast Fulltext Access 7 Pages 2018
Inhibition of mTOR ameliorates bleomycin-induced pulmonary fibrosis by regulating epithelial-mesenchymal transition Fulltext Access 7 Pages 2018
A miR-124/ITGA3 axis contributes to colorectal cancer metastasis by regulating anoikis susceptibility Fulltext Access 7 Pages 2018
Novel phosphorelay-dependent control of ZFP36L1 protein during the cell cycle Fulltext Access 7 Pages 2018
Low expression level of HMBOX1 in high-grade serous ovarian cancer accelerates cell proliferation by inhibiting cell apoptosis Fulltext Access 7 Pages 2018
JLP-JNK signaling protects cancer cells from reactive oxygen species-induced cell death Fulltext Access 7 Pages 2018
UCA1 confers paclitaxel resistance to ovarian cancer through miR-129/ABCB1 axis Fulltext Access 7 Pages 2018
Intravenous Vitamin C attenuates hemorrhagic shock-related renal injury through the induction of SIRT1 in rats Fulltext Access 7 Pages 2018
CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease Fulltext Access 7 Pages 2018
miRNA-152 targets GATA1 to regulate erythropoiesis in Chionodraco hamatus Fulltext Access 7 Pages 2018
NLRP1 deficiency attenuates diabetic retinopathy (DR) in mice through suppressing inflammation response Fulltext Access 7 Pages 2018
An optimal serum-free defined condition for in vitro culture of kidney organoids Fulltext Access 7 Pages 2018
MicroRNA-139-5p suppresses myosin heavy chain I and IIa expression via inhibition of the calcineurin/NFAT signaling pathway Fulltext Access 7 Pages 2018
Cdc42-dependent modulation of rigidity sensing and cell spreading in tumor repopulating cells Fulltext Access 7 Pages 2018
Apixaban attenuates ischemia-induced myocardial fibrosis by inhibition of Gq/PKC signaling Fulltext Access 7 Pages 2018
Ifi27 is indispensable for mitochondrial function and browning in adipocytes Fulltext Access 7 Pages 2018
Decreased serum estrogen improves fat graft retention by enhancing early macrophage infiltration and inducing adipocyte hypertrophy Fulltext Access 7 Pages 2018
RBM14 is indispensable for pluripotency maintenance and mesoderm development of mouse embryonic stem cells Fulltext Access 7 Pages 2018
AFP2 as the novel regulator breaks high-temperature-induced seeds secondary dormancy through ABI5 and SOM in Arabidopsis thaliana Fulltext Access 7 Pages 2018
Mm9_circ_009056 enhances osteogenesis by targeting BMP7 via CGRP-mediated miR-22-3p Fulltext Access 7 Pages 2018
Long non-coding RNA CASP5 promotes the malignant phenotypes of human glioblastoma multiforme Fulltext Access 7 Pages 2018
TNIP1 alleviates hepatic ischemia/reperfusion injury via the TLR2-Myd88 pathway Fulltext Access 7 Pages 2018
Spindle pole body component 25 homolog expressed by ECM stiffening is required for lung cancer cell proliferation Fulltext Access 7 Pages 2018
Modulation of Angiopoietin 2 release from endothelial cells and angiogenesis by the synaptic protein Neuroligin 2 Fulltext Access 7 Pages 2018
Traditional Chinese medication Tongxinluo attenuates apoptosis in ox-LDL-stimulated macrophages by enhancing Beclin-1-induced autophagy Fulltext Access 7 Pages 2018
Aβ1-40 mediated aggregation of proteins and metabolites unveils the relevance of amyloid cross-seeding in amyloidogenesis Fulltext Access 7 Pages 2018
PKC delta activation increases neonatal rat retinal cells survival in vitro: Involvement of neurotrophins and M1 muscarinic receptors Fulltext Access 7 Pages 2018
Transplantation of periaortic adipose tissue inhibits atherosclerosis in apoEâ/â mice by evoking TGF-β1-mediated anti-inflammatory response in transplanted graft Fulltext Access 7 Pages 2018
Identification and expression pattern analysis of BoMYB51 involved in indolic glucosinolate biosynthesis from broccoli (Brassica oleracea var. italica) Fulltext Access 7 Pages 2018
Spatial localisation of Discoidin Domain Receptor 2 (DDR2) signalling is dependent on its collagen binding and kinase activity Fulltext Access 7 Pages 2018
STAT1 activation represses IL-22 gene expression and psoriasis pathogenesis Fulltext Access 7 Pages 2018
Resveratrol alleviates LPS-induced injury in human keratinocyte cell line HaCaT by up-regulation of miR-17 Fulltext Access 7 Pages 2018
Isoprenylcysteine carboxylmethyltransferase regulates ovarian cancer cell response to chemotherapy and Ras activation Fulltext Access 7 Pages 2018
Glycine confers neuroprotection through PTEN/AKT signal pathway in experimental intracerebral hemorrhage Fulltext Access 7 Pages 2018
Induction of inactive TGF-β1 monomer formation by hydrogen sulfide contributes to its suppressive effects on Ang II- and TGF-β1-induced EMT in renal tubular epithelial cells Fulltext Access 7 Pages 2018
Sirt1 S-nitrosylation induces acetylation of HMGB1 in LPS-activated RAW264.7 cells and endotoxemic mice Fulltext Access 7 Pages 2018
Mechanical stress to Drosophila larvae stimulates a cellular immune response through the JAK/STAT signaling pathway Fulltext Access 7 Pages 2018
MicroRNA 148a-3p promotes Thrombospondin-4 expression and enhances angiogenesis during tendinopathy development by inhibiting Krüppel-like factor 6 Fulltext Access 7 Pages 2018
Neuregulin-4 is an angiogenic factor that is critically involved in the maintenance of adipose tissue vasculature Fulltext Access 7 Pages 2018
YY1 promotes IL-6 expression in LPS-stimulated BV2 microglial cells by interacting with p65 to promote transcriptional activation of IL-6 Fulltext Access 7 Pages 2018
Loss of virulence in NAD(P)H cytochrome b5 oxidoreductase deficient Leishmania major Fulltext Access 7 Pages 2018
Crucial role of Reg I from acinar-like cell cluster touching with islets (ATLANTIS) on mitogenesis of beta cells in EMC virus-induced diabetic mice Fulltext Access 7 Pages 2018
The long non-coding RNA PCSEAT exhibits an oncogenic property in prostate cancer and functions as a competing endogenous RNA that associates with EZH2 Fulltext Access 7 Pages 2018
A preliminary study of photoacoustic/ultrasound dual-mode imaging in melanoma using MAGE-targeted gold nanoparticles Fulltext Access 7 Pages 2018
Amide-linked local anesthetics preferentially target leukemia stem cell through inhibition of Wnt/β-catenin Fulltext Access 7 Pages 2018
Expression of ZO1, vimentin, pan-cadherin and AGTR1 in tanycyte-like cells of the sulcus medianus organum Fulltext Access 7 Pages 2018
Enhancement of neuronal differentiation by using small molecules modulating Nodal/Smad, Wnt/β-catenin, and FGF signaling Fulltext Access 7 Pages 2018
Readthrough of ACTN3 577X nonsense mutation produces full-length α-actinin-3 protein Fulltext Access 7 Pages 2018
MiR-455-3p suppresses renal fibrosis through repression of ROCK2 expression in diabetic nephropathy Fulltext Access 7 Pages 2018
miRNA-mediated apoptosis activation through TMEM 48 inhibition in A549 cell line Fulltext Access 7 Pages 2018
Allethrin and prallethrin stimulates MUC5AC expression through oxidative stress in human airway epithelial cells Fulltext Access 7 Pages 2018
Anti-melanogenic activity of schaftoside in Rhizoma Arisaematis by increasing autophagy in B16F1 cells Fulltext Access 7 Pages 2018
PTP1B promotes the malignancy of ovarian cancer cells in a JNK-dependent mechanism Fulltext Access 7 Pages 2018
Delavatine A, an unusual isoquinoline alkaloid exerts anti-inflammation on LPS-induced proinflammatory cytokines production by suppressing NF-κB activation in BV-2 microglia Fulltext Access 7 Pages 2018
Histone methyltransferase SETD2 regulates osteosarcoma cell growth and chemosensitivity by suppressing Wnt/β-catenin signaling Fulltext Access 7 Pages 2018
Lactic acid induces lactate transport and glycolysis/OXPHOS interconversion in glioblastoma Fulltext Access 7 Pages 2018
Aspirin restores ABT-737-mediated apoptosis in human renal carcinoma cells Fulltext Access 7 Pages 2018
Mechanisms involved in epigenetic down-regulation of Gfap under maternal hypothyroidism Fulltext Access 7 Pages 2018
Octanoic acid potentiates glucose-stimulated insulin secretion and expression of glucokinase through the olfactory receptor in pancreatic β-cells Fulltext Access 7 Pages 2018
Circular RNA HIPK3 promotes gallbladder cancer cell growth by sponging microRNA-124 Fulltext Access 7 Pages 2018
ATP6V1H regulates the growth and differentiation of bone marrow stromal cells Fulltext Access 7 Pages 2018
PAFAH1B2 is a HIF1a target gene and promotes metastasis in pancreatic cancer Fulltext Access 7 Pages 2018
Proteasome-mediated protein degradation is enhanced by fusion ubiquitin with unstructured degron Fulltext Access 7 Pages 2018
Autophagy mediates enhancement of proangiogenic activity by hypoxia in mesenchymal stromal/stem cells Fulltext Access 7 Pages 2018
Neuroligin-3 protects retinal cells from H2O2-induced cell death via activation of Nrf2 signaling Fulltext Access 7 Pages 2018
Identification and characterization of the zinc finger protein SjZF in Schistosoma japonicum Fulltext Access 7 Pages 2018
ELK1-induced upregulation of lncRNA HOXA10-AS promotes lung adenocarcinoma progression by increasing Wnt/β-catenin signaling Fulltext Access 7 Pages 2018
TGF-β1 induced fascin1 expression facilitates the migration and invasion of kidney carcinoma cells through ERK and JNK signaling pathways Fulltext Access 7 Pages 2018
Erybraedin A is a potential Src inhibitor that blocks the adhesion and viability of non-small-cell lung cancer cells Fulltext Access 7 Pages 2018
Crystal structure of WA352 provides insight into cytoplasmic male sterility in rice Fulltext Access 7 Pages 2018
In vivo gene correction with targeted sequence substitution through microhomology-mediated end joining Fulltext Access 7 Pages 2018
Different players generate positive responses in two in vitro cytokine assay formats with aqueous and immobilized TGN1412 analog Fulltext Access 7 Pages 2018
SIRT1 promotes proliferation, migration, and invasion of breast cancer cell line MCF-7 by upregulating DNA polymerase delta1 (POLD1) Fulltext Access 7 Pages 2018
Cholesterol promotes the migration and invasion of renal carcinoma cells by regulating the KLF5/miR-27a/FBXW7 pathway Fulltext Access 7 Pages 2018
Resveratrol prolongs lifespan and improves 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced oxidative damage and behavioural deficits in Drosophila melanogaster Fulltext Access 7 Pages 2018
Naringenin exhibits the protective effect on cardiac hypertrophy via EETs-PPARs activation in streptozocin-induced diabetic mice Fulltext Access 7 Pages 2018
Inhibition of microRNA-16 facilitates the paclitaxel resistance by targeting IKBKB via NF-κB signaling pathway in hepatocellular carcinoma Fulltext Access 7 Pages 2018
Cleavage of molybdopterin synthase MoaD-MoaE linear fusion by JAMM/MPN+ domain containing metalloprotease DR0402 from Deinococcus radiodurans Fulltext Access 7 Pages 2018
Overexpression of TUSC7 inhibits the inflammation caused by microglia activation via regulating miR-449a/PPAR-γ Fulltext Access 7 Pages 2018
RNA interference in vivo in Schistosoma japonicum: Establishing and optimization of RNAi mediated suppression of gene expression by long dsRNA in the intra-mammalian life stages of worms Fulltext Access 7 Pages 2018
Amelioration of myocardial ischemia-reperfusion injury by SIRT4 involves mitochondrial protection and reduced apoptosis Fulltext Access 7 Pages 2018
The E3 ubiquitin ligase RNF146 promotes colorectal cancer by activating the Wnt/β-catenin pathway via ubiquitination of Axin1 Fulltext Access 7 Pages 2018