Giantin is required for coordinated production of aggrecan, link protein and type XI collagen during chondrogenesis Fulltext Access 7 Pages 2018
Engineering of DNA polymerase I from Thermus thermophilus using compartmentalized self-replication Fulltext Access 7 Pages 2018
Regulator of G-protein signalling 5 deficiency impairs ventricular remodelling after myocardial infarction by promoting NF-κB and MAPK signalling in mice Fulltext Access 7 Pages 2018
Structural and biochemical characterization of the type-II LOG protein from Streptomyces coelicolor A3 Fulltext Access 7 Pages 2018
A novel TBX1 missense mutation in patients with syndromic congenital heart defects Fulltext Access 7 Pages 2018
Discovery and characterization of selective small molecule inhibitors of the mammalian mitochondrial division dynamin, DRP1 Fulltext Access 7 Pages 2018
TNF receptor associated factor 5 controls oncostatin M-mediated lung inflammation Fulltext Access 7 Pages 2018
AZD5153, a novel BRD4 inhibitor, suppresses human thyroid carcinoma cell growth in vitro and in vivo Fulltext Access 7 Pages 2018
CXCL8 is associated with the recurrence of patients with acute myeloid leukemia and cell proliferation in leukemia cell lines Fulltext Access 7 Pages 2018
Loss of nucleolar localization of NAT10 promotes cell migration and invasion in hepatocellular carcinoma Fulltext Access 7 Pages 2018
Liposome-encapsulated clodronate specifically depletes spinal microglia and reduces initial neuropathic pain Fulltext Access 7 Pages 2018
TICAM-1 is dispensable in STING-mediated innate immune responses in myeloid immune cells Fulltext Access 7 Pages 2018
Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH Fulltext Access 7 Pages 2018
A new vaccine targeting RANKL, prepared by incorporation of an unnatural Amino acid into RANKL, prevents OVX-induced bone loss in mice Fulltext Access 7 Pages 2018
Substance P preserves pancreatic β-cells in type 1 and type 2 diabetic mice Fulltext Access 7 Pages 2018
Variations in gut microbiota and fecal metabolic phenotype associated with Fenbendazole and Ivermectin Tablets by 16S rRNA gene sequencing and LC/MS-based metabolomics in Amur tiger Fulltext Access 7 Pages 2018
Nicotine induces aberrant hypermethylation of tumor suppressor genes in pancreatic epithelial ductal cells Fulltext Access 7 Pages 2018
PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization Fulltext Access 7 Pages 2018
Tyrosine kinase activity of EphA2 promotes its S897 phosphorylation and glioblastoma cell proliferation Fulltext Access 7 Pages 2018
Long non-coding RNA THOR promotes human osteosarcoma cell growth in vitro and in vivo Fulltext Access 7 Pages 2018
Enoyl coenzyme A hydratase 1 protects against high-fat-diet-induced hepatic steatosis and insulin resistance Fulltext Access 7 Pages 2018
Oncogenic MicroRNA-20a is downregulated by the HIF-1α/c-MYC pathway in IDH1 R132H-mutant glioma Fulltext Access 7 Pages 2018
LncRNA TP73-AS1 predicts the prognosis of bladder cancer patients and functions as a suppressor for bladder cancer by EMT pathway Fulltext Access 7 Pages 2018
Cephalosporin antibiotics are weak blockers of GABAa receptor-mediated synaptic transmission in rat brain slices Fulltext Access 7 Pages 2018
Anti-angiogenic effect of Interleukin-26 in oxygen-induced retinopathy mice via inhibiting NFATc1-VEGF pathway Fulltext Access 7 Pages 2018
Identification and analysis of microRNAs-mRNAs pairs associated with nutritional status in seasonal sheep Fulltext Access 7 Pages 2018
Alpha-helical domain from IL-8 of salmonids: Mechanism of action and identification of a novel antimicrobial function Fulltext Access 7 Pages 2018
Structure of a [NiFe] hydrogenase maturation protease HycI provides insights into its substrate selectivity Fulltext Access 7 Pages 2018
Programmed death ligand 1 expression and CD8+ tumor-infiltrating lymphocyte density differences between paired primary and brain metastatic lesions in non-small cell lung cancer Fulltext Access 7 Pages 2018
Self-organizing cortex generated from human iPSCs with combination of FGF2 and ambient oxygen Fulltext Access 7 Pages 2018
Engineered U7 snRNA mediates sustained splicing correction in erythroid cells from β-thalassemia/HbE patients Fulltext Access 7 Pages 2018
A novel lentiviral scFv display library for rapid optimization and selection of high affinity antibodies Fulltext Access 7 Pages 2018
R-spondin3-LGR4 signaling protects hepatocytes against DMOG-induced hypoxia/reoxygenation injury through activating β-catenin Fulltext Access 7 Pages 2018
MicroRNA-585 suppresses tumor proliferation and migration in gastric cancer by directly targeting MAPK1 Fulltext Access 7 Pages 2018
Genome-wide identification and expression analysis of the fatty acid desaturase genes in Medicago truncatula Fulltext Access 7 Pages 2018
Histone and RNA-binding protein interaction creates crosstalk network for regulation of alternative splicing Fulltext Access 7 Pages 2018
PDLIM5 identified by label-free quantitative proteomics as a potential novel biomarker of papillary thyroid carcinoma Fulltext Access 7 Pages 2018
Silencing LncRNA LOXL1-AS1 attenuates mesenchymal characteristics of glioblastoma via NF-κB pathway Fulltext Access 7 Pages 2018
miR-126-5p targets Malate Dehydrogenase 1 in non-small cell lung carcinomas Fulltext Access 7 Pages 2018
CsTFL1b may regulate the flowering time and inflorescence architecture in cucumber (Cucumis sativus L.) Fulltext Access 7 Pages 2018
Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-κB recruitment Fulltext Access 7 Pages 2018
Involvement of phosphatidylinositol-3 kinase/Akt/mammalian target of rapamycin/peroxisome proliferator-activated receptor γ pathway for induction and maintenance of neuropathic pain Fulltext Access 7 Pages 2018
Molecular association model of PPARα and its new specific and efficient ligand, pemafibrate: Structural basis for SPPARMα Fulltext Access 7 Pages 2018
Novel gadopentetic acid-doped silica nanoparticles conjugated with YPSMA-1 targeting prostate cancer for MR imaging: an in vitro study Fulltext Access 7 Pages 2018
TDP-43 NTD can be induced while CTD is significantly enhanced by ssDNA to undergo liquid-liquid phase separation Fulltext Access 7 Pages 2018
Resveratrol protects HaCaT cells from ultraviolet B-induced photoaging via upregulation of HSP27 and modulation of mitochondrial caspase-dependent apoptotic pathway Fulltext Access 7 Pages 2018
Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells Fulltext Access 7 Pages 2018
CSN5/Jab1 facilitates non-small cell lung cancer cell growth through stabilizing survivin Fulltext Access 7 Pages 2018
Down-regulation of TRAF4 targeting RSK4 inhibits proliferation, invasion and metastasis in breast cancer xenografts Fulltext Access 7 Pages 2018
ER stress attenuation by Aloe-derived polysaccharides in the protection of pancreatic β-cells from free fatty acid-induced lipotoxicity Fulltext Access 7 Pages 2018
Nrf2 activation protects against intratracheal LPS induced mouse/murine acute respiratory distress syndrome by regulating macrophage polarization Fulltext Access 7 Pages 2018
FGF8 and FGFR3 are up-regulated in hypertrophic chondrocytes: Association with chondrocyte death in deep zone of Kashin-Beck disease Fulltext Access 7 Pages 2018
Knockout of NCOA5 impairs proliferation and migration of hepatocellular carcinoma cells by suppressing epithelial-to-mesenchymal transition Fulltext Access 7 Pages 2018
Specificity and utility of SubB2M, a new N-glycolylneuraminic acid lectin Fulltext Access 7 Pages 2018
Exosomal miR-675 from metastatic osteosarcoma promotes cell migration and invasion by targeting CALN1 Fulltext Access 7 Pages 2018
HMGB1-containing nucleosome mediates chemotherapy-induced metastasis of human lung cancer Fulltext Access 7 Pages 2018
Generation of splice switching oligonucleotides targeting the Cockayne syndrome group B gene product in order to change the diseased cell state Fulltext Access 7 Pages 2018
Activation of TLR3 and its adaptor TICAM-1 increases miR-21 levels in extracellular vesicles released from human cells Fulltext Access 7 Pages 2018
Micro124-mediated AHR expression regulates the inflammatory response of chronic rhinosinusitis (CRS) with nasal polyps Fulltext Access 7 Pages 2018
ShRNA-mediated knock-down of CXCL8 inhibits tumor growth in colorectal liver metastasis Fulltext Access 7 Pages 2018
The chemorepellent draxin is involved in hippocampal mossy fiber projection Fulltext Access 7 Pages 2018
Metformin ameliorates TGF-β1-induced osteoblastic differentiation of human aortic valve interstitial cells by inhibiting β-catenin signaling Fulltext Access 7 Pages 2018
Chronic cold exposure results in subcutaneous adipose tissue browning and altered global metabolism in Qinghai-Tibetan plateau pika (Ochotona curzoniae) Fulltext Access 7 Pages 2018
Regional up-regulation of NOX2 contributes to the differential vulnerability of outer hair cells to neomycin Fulltext Access 7 Pages 2018
Membrane glycerolipid equilibrium under endoplasmic reticulum stress in Arabidopsis thaliana Fulltext Access 7 Pages 2018
CBX3 promotes proliferation and regulates glycolysis via suppressing FBP1 in pancreatic cancer Fulltext Access 7 Pages 2018
Long non-protein coding RNA DANCR functions as a competing endogenous RNA to regulate osteoarthritis progression via miR-577/SphK2 axis Fulltext Access 7 Pages 2018
Genome-wide profiles of metastasis-associated mRNAs and microRNAs in salivary adenoid cystic carcinoma Fulltext Access 7 Pages 2018
LincRNA-RoR/miR-145 promote invasion and metastasis in triple-negative breast cancer via targeting MUC1 Fulltext Access 7 Pages 2018
Neutrophils infiltrating pancreatic ductal adenocarcinoma indicate higher malignancy and worse prognosis Fulltext Access 7 Pages 2018
Altered expression of PGC-1α and PDX1 and their methylation status are associated with fetal glucose metabolism in gestational diabetes mellitus Fulltext Access 7 Pages 2018
PF-06409577 activates AMPK signaling to protect retinal pigment epithelium cells from UV radiation Fulltext Access 7 Pages 2018
Downregulation of circ_008018 protects against cerebral ischemia-reperfusion injury by targeting miR-99a Fulltext Access 7 Pages 2018
Circular RNA circNASP modulates the malignant behaviors in osteosarcoma via miR-1253/FOXF1 pathway Fulltext Access 7 Pages 2018
Osh6p, a homologue of the oxysterol-binding protein, is involved in production of functional cytochrome P450 belonging to CYP52 family in n-alkane-assimilating yeast Yarrowia lipolytica Fulltext Access 7 Pages 2018
Sildenafil protects neuronal cells from mitochondrial toxicity induced by β-amyloid peptide via ATP-sensitive K+ channels Fulltext Access 7 Pages 2018
Glycolytic inhibitor 2-Deoxy-d-Glucose activates migration and invasion in glioblastoma cells through modulation of the miR-7-5p/TFF3 signaling pathway Fulltext Access 7 Pages 2018
Augmented neutrophil extracellular traps formation promotes atherosclerosis development in socially defeated apoEâ/â mice Fulltext Access 7 Pages 2018
Caspase-2 associates with FAN through direct interaction and overlapping functionality Fulltext Access 7 Pages 2018
Krüppel-like factor 9 suppressed tumorigenicity of the pancreatic ductal adenocarcinoma by negatively regulating frizzled-5 Fulltext Access 7 Pages 2018
DNA damage response signaling does not trigger redistribution of SAMHD1 to nuclear foci Fulltext Access 7 Pages 2018
Loss of RapC causes defects in cytokinesis, cell migration, and multicellular development of Dictyostelium Fulltext Access 7 Pages 2018
Transcription of blunt snout bream (Megalobrama amblycephala) HIF3α and its localization in the nucleus under both normoxic and hypoxic conditions Fulltext Access 7 Pages 2018
Hsa_circ_0007534/miR-761/ZIC5 regulatory loop modulates the proliferation and migration of glioma cells Fulltext Access 7 Pages 2018
Designing an effective drug combination for ER stress loading in cancer therapy using a real-time monitoring system Fulltext Access 7 Pages 2018
Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2 Fulltext Access 7 Pages 2018
Methylation-induced silencing of SPG20 facilitates gastric cancer cell proliferation by activating the EGFR/MAPK pathway Fulltext Access 7 Pages 2018
Interleukin-enhanced binding factor 2 interacts with NLRP3 to inhibit the NLRP3 inflammasome activation Fulltext Access 7 Pages 2018
PPM1B depletion in U2OS cells supresses cell growth through RB1-E2F1 pathway and stimulates bleomycin-induced cell death Fulltext Access 7 Pages 2018
Orai1 downregulation impairs lymphocyte function in type 2 diabetes mellitus Fulltext Access 7 Pages 2018
Visceral adipose tissue-derived serine protease inhibitor accelerates cholesterol efflux by up-regulating ABCA1 expression via the NF-κB/miR-33a pathway in THP-1 macropahge-derived foam cells Fulltext Access 7 Pages 2018
Role of IκB kinase β in regulating the remodeling of the CARMA1-Bcl10-MALT1 complex Fulltext Access 7 Pages 2018
ST6GAL1 negatively regulates monocyte transendothelial migration and atherosclerosis development Fulltext Access 7 Pages 2018
Down-regulation of FOXR2 inhibits non-small cell lung cancer cell proliferation and invasion through the Wnt/β-catenin signaling pathway Fulltext Access 7 Pages 2018
Recovery of active recombinant EGFP from the excrement of transgenic mice: A possible source of recombinant protein Fulltext Access 7 Pages 2018