Synergistic activity of BET inhibitor BI 894999 with PLK inhibitor volasertib in AML in vitro and in vivo Fulltext Access 33 Pages 2018
Novel tumor necrosis factor-α induced protein eight (TNFAIP8/TIPE) family: Functions and downstream targets involved in cancer progression Fulltext Access 33 Pages 2018
Definitive treatment patterns and survival in stage II non-small cell lung cancer Fulltext Access 33 Pages 2018
KDM6 and KDM4 histone lysine demethylases emerge as molecular therapeutic targets in human acute myeloid leukemia Fulltext Access 33 Pages 2018
Comprehensive pharmacogenomic profiling of human papillomavirus-positive and -negative squamous cell carcinoma identifies sensitivity to aurora kinase inhibition in KMT2D mutants Fulltext Access 33 Pages 2018
Acquisition of tumorigenic potential and therapeutic resistance in CD133+ subpopulation of prostate cancer cells exhibiting stem-cell like characteristics Fulltext Access 33 Pages 2018
ASC-J9® suppresses prostate cancer cell invasion via altering the sumoylation-phosphorylation of STAT3 Fulltext Access 33 Pages 2018
Survivin-targeted drug screening platform identifies a matrine derivative WM-127 as a potential therapeutics against hepatocellular carcinoma Fulltext Access 33 Pages 2018
Elevated phospholipase D activity in androgen-insensitive prostate cancer cells promotes both survival and metastatic phenotypes Fulltext Access 33 Pages 2018
Sabutoclax, pan-active BCL-2 protein family antagonist, overcomes drug resistance and eliminates cancer stem cells in breast cancer Fulltext Access 33 Pages 2018
Alteration in microRNA-25 expression regulate cardiac function via renin secretion Fulltext Access 33 Pages 2018
Pyrazolo[1,5-a]pyrimidine TRPC6 antagonists for the treatment of gastric cancer Fulltext Access 33 Pages 2018
Oncogene-induced regulation of microRNA expression: Implications for cancer initiation, progression and therapy Fulltext Access 33 Pages 2018
Loss of TGF-β signaling in osteoblasts increases basic-FGF and promotes prostate cancer bone metastasis Fulltext Access 33 Pages 2018
RHBDF1 regulates APC-mediated stimulation of the epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells in part via the Wnt/β-catenin signalling pathway Fulltext Access 33 Pages 2018
The development of methods for primary mast cells in vitro and ex vivo: An historical review Fulltext Access 33 Pages 2018
Influence of HPV-status on survival of patients with tonsillar carcinomas (TSCC) treated by CO2-laser surgery plus risk adapted therapy - A 10 year retrospective single centre study Fulltext Access 33 Pages 2018
CXCR2 promotes breast cancer metastasis and chemoresistance via suppression of AKT1 and activation of COX2 Fulltext Access 33 Pages 2018
Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents Fulltext Access 33 Pages 2018
TGF-β1 targets a microRNA network that regulates cellular adhesion and migration in renal cancer Fulltext Access 33 Pages 2018
Apoptosis-Inducing Factor (AIF) in Physiology and Disease: The Tale of a Repented Natural Born Killer Fulltext Access 33 Pages 2018
MiR-192 and miR-662 enhance chemoresistance and invasiveness of squamous cell lung carcinoma Fulltext Access 33 Pages 2018
The suppression effect of dendritic cells maturation by adipose-derived stem cells through TGF-β1 related pathway Fulltext Access 33 Pages 2018
FTY720 enhances the anti-tumor activity of carboplatin and tamoxifen in a patient-derived xenograft model of ovarian cancer Fulltext Access 33 Pages 2018
Three new disease-progression modes in NSCLC patients after EGFR-TKI treatment by next-generation sequencing analysis Fulltext Access 33 Pages 2018
RNA interference to enhance radiation therapy: Targeting the DNA damage response Fulltext Access 33 Pages 2018
Layer-by-layer nanofiber-enabled engineering of biomimetic periosteum for bone repair and reconstruction Fulltext Access 34 Pages 2018
Collagen VI disorders: Insights on form and function in the extracellular matrix and beyond Fulltext Access 34 Pages 2018
Cathepsin D enhances breast cancer invasion and metastasis through promoting hepsin ubiquitin-proteasome degradation Fulltext Access 34 Pages 2018
Wnt11 alters integrin and cadherin expression by ovarian cancer spheroids and inhibits tumorigenesis and metastasis Fulltext Access 34 Pages 2018
Monitoring clinical outcomes in aggressive B-cell lymphoma: From imaging studies to circulating tumor DNA Fulltext Access 34 Pages 2018
Molecular genetics of the POMT1-related muscular dystrophy-dystroglycanopathies Fulltext Access 34 Pages 2018
Induction chemoradiotherapy versus chemotherapy alone for superior sulcus lung cancer Fulltext Access 34 Pages 2018
Complement 5a stimulates macrophage polarization and contributes to tumor metastases of colon cancer Fulltext Access 34 Pages 2018
A double-negative feedback loop between DEAD-box protein DDX21 and Snail regulates epithelial-mesenchymal transition and metastasis in breast cancer Fulltext Access 34 Pages 2018
Activation of human aortic valve interstitial cells by local stiffness involves YAP-dependent transcriptional signaling Fulltext Access 34 Pages 2018
The role of oligodendrocytes and their progenitors on neural interface technology: A novel perspective on tissue regeneration and repair Fulltext Access 34 Pages 2018
Diagnostic utility of glycosyltransferase mRNA expression in gastric cancer Fulltext Access 34 Pages 2018
Fucosyltransferase 2 induced epithelial-mesenchymal transition via TGF-β/Smad signaling pathway in lung adenocarcinaoma Fulltext Access 34 Pages 2018
PLGA nanoparticles with multiple modes are a biologically safe nanocarrier for mammalian development and their offspring Fulltext Access 34 Pages 2018
Time-dependent transcriptional response of GOT1 human small intestine neuroendocrine tumor after 177Lu[Lu]-octreotate therapy Fulltext Access 34 Pages 2018
Crucial role of HO-1/IRF4-dependent apoptosis induced by panobinostat and lenalidomide in multiple myeloma Fulltext Access 34 Pages 2018
Impact of structural alterations on the radiopharmacological profile of 18F-labeled pyrimidines as cyclooxygenase-2 (COX-2) imaging agents Fulltext Access 34 Pages 2018
PDGF-mediated PI3K/AKT/β-catenin signaling regulates gap junctions in corpus cavernosum smooth muscle cells Fulltext Access 34 Pages 2018
NLRP3 inflammasome inhibition attenuates silica-induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells Fulltext Access 34 Pages 2018
Establishment of a method for in-vivo SPECT/CT imaging analysis of 111In-labeled exendin-4 pancreatic uptake in mice without the need for nephrectomy or a secondary probe Fulltext Access 34 Pages 2018
Non-Glycanated Biglycan and LTBP4: Leveraging the extracellular matrix for Duchenne Muscular Dystrophy therapeutics Fulltext Access 34 Pages 2018
3D printed biofunctionalized scaffolds for microfracture repair of cartilage defects Fulltext Access 34 Pages 2018
Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model Fulltext Access 34 Pages 2018
A PTX/nitinol stent combination with temperature-responsive phase-change 1-hexadecanol for magnetocaloric drug delivery: Magnetocaloric drug release and esophagus tissue penetration Fulltext Access 34 Pages 2018
Telomerase reverse transcriptase regulates DNMT3B expression/aberrant DNA methylation phenotype and AKT activation in hepatocellular carcinoma Fulltext Access 34 Pages 2018
Allogeneic Stem Cell Transplantation versus Tyrosine Kinase Inhibitors Combined with Chemotherapy in Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Fulltext Access 34 Pages 2018
The C-terminal tail of the NEIL1 DNA glycosylase interacts with the human mitochondrial single-stranded DNA binding protein Fulltext Access 34 Pages 2018
Multiple roles of the splicing complex SF3B in DNA end resection and homologous recombination Fulltext Access 34 Pages 2018
ILK-induced epithelial-mesenchymal transition promotes the invasive phenotype in adenomyosis Fulltext Access 34 Pages 2018
Hv1 proton channel facilitates production of ROS and pro-inflammatory cytokines in microglia and enhances oligodendrocyte progenitor cells damage from oxygen-glucose deprivation in vitro Fulltext Access 34 Pages 2018
Ultrasensitive MRI detection of spontaneous pancreatic tumors with nanocage-based targeted contrast agent Fulltext Access 34 Pages 2018
MicroRNA-30a suppresses autophagy-mediated anoikis resistance and metastasis in hepatocellular carcinoma Fulltext Access 34 Pages 2018
Semiconducting polymer-based nanoparticles with strong absorbance in NIR-II window for in vivo photothermal therapy and photoacoustic imaging Fulltext Access 34 Pages 2018
Comparing ex vivo and in vitro translocation of silver nanoparticles and ions through human nasal epithelium Fulltext Access 34 Pages 2018
NIR-controlled morphology transformation and pulsatile drug delivery based on multifunctional phototheranostic nanoparticles for photoacoustic imaging-guided photothermal-chemotherapy Fulltext Access 34 Pages 2018
Decellularized peripheral nerve supports Schwann cell transplants and axon growth following spinal cord injury Fulltext Access 34 Pages 2018
Anti-inflammatory polymersomes of redox-responsive polyprodrug amphiphiles with inflammation-triggered indomethacin release characteristics Fulltext Access 34 Pages 2018
Mechanically cartilage-mimicking poly(PCL-PTHF urethane)/collagen nanofibers induce chondrogenesis by blocking NF-kappa B signaling pathway Fulltext Access 34 Pages 2018
Long-term monitoring of tumor-related autophagy in vivo by Fe3O4NO· nanoparticles Fulltext Access 34 Pages 2018
Thermosensitive biomimetic polyisocyanopeptide hydrogels may facilitate wound repair Fulltext Access 34 Pages 2018
Transcriptional repressor Kaiso promotes epithelial to mesenchymal transition and metastasis in prostate cancer through direct regulation of miR-200c Fulltext Access 34 Pages 2018
Correlates of Protection Against SIVmac251 Infection in Rhesus Macaques Immunized With Chimpanzee-Derived Adenovirus Vectors Fulltext Access 34 Pages 2018
LB-100, a novel Protein Phosphatase 2A (PP2A) inhibitor, sensitizes malignant meningioma cells to the therapeutic effects of radiation Fulltext Access 34 Pages 2018
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness Fulltext Access 34 Pages 2018
NFYB-induced high expression of E2F1 contributes to oxaliplatin resistance in colorectal cancer via the enhancement of CHK1 signaling Fulltext Access 34 Pages 2018
Pan-HDAC inhibition by panobinostat mediates chemosensitization to carboplatin in non-small cell lung cancer via attenuation of EGFR signaling Fulltext Access 34 Pages 2018
Synthetic artificial "long non-coding RNAs" targeting oncogenic microRNAs and transcriptional factors inhibit malignant phenotypes of bladder cancer cells Fulltext Access 34 Pages 2018
DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer Fulltext Access 34 Pages 2018
CISD2 inhibition overcomes resistance to sulfasalazine-induced ferroptotic cell death in head and neck cancer Fulltext Access 34 Pages 2018
Decrease in phosphorylated ERK indicates the therapeutic efficacy of a clinical PI3Kα-selective inhibitor CYH33 in breast cancer Fulltext Access 34 Pages 2018
IL6/STAT3 axis mediates resistance to BRAF inhibitors in thyroid carcinoma cells Fulltext Access 34 Pages 2018
Indoleamine 2,3-dioxygenase 1 inhibition targets anti-PD1-resistant lung tumors by blocking myeloid-derived suppressor cells Fulltext Access 34 Pages 2018
RUNX1 promotes cell growth in human T-cell acute lymphoblastic leukemia by transcriptional regulation of key target genes Fulltext Access 35 Pages 2018
Comprehensive BRCA mutation analysis in the Greek population. Experience from a single clinical diagnostic center Fulltext Access 35 Pages 2018
Hematopoietic insults damage bone marrow niche by activating p53 in vascular endothelial cells Fulltext Access 35 Pages 2018
Involvement of LPA signaling via LPA receptor-2 in the promotion of malignant properties in osteosarcoma cells Fulltext Access 35 Pages 2018
Hypoxia-induced autophagy activation through NF-κB pathway regulates cell proliferation and migration to induce pulmonary vascular remodeling Fulltext Access 35 Pages 2018
VEGFR-3 signaling is regulated by a G-protein activator, activator of G-protein signaling 8, in lymphatic endothelial cells Fulltext Access 35 Pages 2018
Reversal of T Cell Exhaustion by the First Donor Lymphocyte Infusion Is Associated with the Persistently Effective Antileukemic Responses in Patients with Relapsed AML after Allo-HSCT Fulltext Access 35 Pages 2018
PRMT1 negatively regulates activation-induced cell death in macrophages by arginine methylation of GAPDH Fulltext Access 35 Pages 2018
Vangl2 is essential for myocardial remodeling activated by Wnt/JNK signaling Fulltext Access 35 Pages 2018
[18F]Diphenyl sulfide derivatives for imaging serotonin transporter (SERT) in the brain Fulltext Access 35 Pages 2018
Influence of transport line material on the molar activity of cyclotron produced [18F]fluoride Fulltext Access 35 Pages 2018
Monitoring autophagic flux using p62/SQSTM1 based luciferase reporters in glioma cells Fulltext Access 35 Pages 2018
Myosin-IIA heavy chain phosphorylation on S1943 regulates tumor metastasis Fulltext Access 35 Pages 2018