The hypoxic tumor microenvironment in vivo selects tumor cells with increased survival against genotoxic stresses Fulltext Access 35 Pages 2018
The developmental transcription factor IRF6 attenuates ABCG2 gene expression and distinctively reverses stemness phenotype in nasopharyngeal carcinoma Fulltext Access 35 Pages 2018
C/EBPβ contributes to transcriptional activation of long non-coding RNA NEAT1 during APL cell differentiation Fulltext Access 35 Pages 2018
Dacomitinib antagonizes multidrug resistance (MDR) in cancer cells by inhibiting the efflux activity of ABCB1 and ABCG2 transporters Fulltext Access 35 Pages 2018
Long non-coding RNA XIST promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-367/141-ZEB2 axis in non-small-cell lung cancer Fulltext Access 35 Pages 2018
Mutant cartilage oligomeric matrix protein (COMP) compromises bone integrity, joint function and the balance between adipogenesis and osteogenesis Fulltext Access 35 Pages 2018
Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer Fulltext Access 35 Pages 2018
Extraction of radiomic values from lung adenocarcinoma with near-pure subtypes in the International Association for the Study of Lung Cancer/the American Thoracic Society/the European Respiratory Society (IASLC/ATS/ERS) classification Fulltext Access 35 Pages 2018
A fluorescent chemical probe CDy9 selectively stains and enables the isolation of live naïve mouse embryonic stem cells Fulltext Access 35 Pages 2018
CAPACITY: A physical activity self-management program for patients undergoing surgery for lung cancer, a phase I feasibility study Fulltext Access 35 Pages 2018
A prodrug of green tea polyphenol (-)-epigallocatechin-3-gallate (Pro-EGCG) serves as a novel angiogenesis inhibitor in endometrial cancer Fulltext Access 35 Pages 2018
IGFBP2 promotes salivary adenoid cystic carcinoma metastasis by activating the NF-κB/ZEB1 signaling pathway Fulltext Access 35 Pages 2018
Integrin α5 down-regulation by miR-205 suppresses triple negative breast cancer stemness and metastasis by inhibiting the Src/Vav2/Rac1 pathway Fulltext Access 35 Pages 2018
Transcriptome analysis identifies genes involved in sex determination and development of Xenopus laevis gonads Fulltext Access 35 Pages 2018
HDAC1-induced epigenetic silencing of ASPP2 promotes cell motility, tumour growth and drug resistance in renal cell carcinoma Fulltext Access 35 Pages 2018
Biomimetic elastomeric, conductive and biodegradable polycitrate-based nanocomposites for guiding myogenic differentiation and skeletal muscle regeneration Fulltext Access 35 Pages 2018
The effect of surface poly(ethylene glycol) length on in vivo drug delivery behaviors of polymeric nanoparticles Fulltext Access 35 Pages 2018
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis Fulltext Access 35 Pages 2018
Photo-excitable hybrid nanocomposites for image-guided photo/TRAIL synergistic cancer therapy Fulltext Access 35 Pages 2018
miRNA 146a promotes chemotherapy resistance in lung cancer cells by targeting DNA damage inducible transcript 3 (CHOP) Fulltext Access 35 Pages 2018
Anti-CD73 and anti-OX40 immunotherapy coupled with a novel biocompatible enzyme prodrug system for the treatment of recurrent, metastatic ovarian cancer Fulltext Access 35 Pages 2018
Fucoidan/VEGF-based surface modification of decellularized pulmonary heart valve improves the antithrombotic and re-endothelialization potential of bioprostheses Fulltext Access 35 Pages 2018
FAK- and YAP/TAZ dependent mechanotransduction pathways are required for enhanced immunomodulatory properties of adipose-derived mesenchymal stem cells induced by aligned fibrous scaffolds Fulltext Access 35 Pages 2018
“Stepwise Extraction” strategy-based injectable bioresponsive composite implant for cancer theranostics Fulltext Access 35 Pages 2018
Injectable and detachable heparin-based hydrogel micropatches for hepatic differentiation of hADSCs and their liver targeted delivery Fulltext Access 35 Pages 2018
Tim-4 promotes the growth of colorectal cancer by activating angiogenesis and recruiting tumor-associated macrophages via the PI3K/AKT/mTOR signaling pathway Fulltext Access 35 Pages 2018
A novel strategy of integrated microarray analysis identifies CENPA, CDK1 and CDC20 as a cluster of diagnostic biomarkers in lung adenocarcinoma Fulltext Access 36 Pages 2018
Osteoblast-secreted WISP-1 promotes adherence of prostate cancer cells to bone via the VCAM-1/integrin α4β1 system Fulltext Access 36 Pages 2018
Metabolic profiling associated with autophagy of human placenta-derived mesenchymal stem cells by chemical isotope labeling LCâMS Fulltext Access 36 Pages 2018
Bafilomycin A1 increases the sensitivity of tongue squamous cell carcinoma cells to cisplatin by inhibiting the lysosomal uptake of platinum ions but not autophagy Fulltext Access 36 Pages 2018
Time-course analysis of microRNA-induced mesenchymal-to-epithelial transition underscores the complexity of the underlying molecular processes Fulltext Access 36 Pages 2018
Sodium Butyrate Inhibits Inflammation and Maintains Epithelium Barrier Integrity in a TNBS-induced Inflammatory Bowel Disease Mice Model Fulltext Access 36 Pages 2018
Bone Marrow Transplantation after Nonmyeloablative Treosulfan Conditioning Is Curative in a Murine Model of Sickle Cell Disease Fulltext Access 36 Pages 2018
TRAIL-secreting human mesenchymal stem cells engineered by a non-viral vector and photochemical internalization for pancreatic cancer gene therapy Fulltext Access 36 Pages 2018
Upregulation of long non-coding RNA RAB1A-2 induces FGF1 expression worsening lung cancer prognosis Fulltext Access 36 Pages 2018
IFN-γ synergism with poly I:C reduces growth of murine and human cancer cells with simultaneous changes in cell cycle and immune checkpoint proteins Fulltext Access 36 Pages 2018
Smoothened stabilizes and protects TRAF6 from degradation: A novel non-canonical role of smoothened with implications in lymphoma biology Fulltext Access 36 Pages 2018
Prognostication of diffuse large B-cell lymphoma in the molecular era: moving beyond the IPI Fulltext Access 36 Pages 2018
SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling Fulltext Access 36 Pages 2018
Myosin Id localizes in dendritic spines through the tail homology 1 domain Fulltext Access 36 Pages 2018
TGF-β-induced STAT3 overexpression promotes human head and neck squamous cell carcinoma invasion and metastasis through malat1/miR-30a interactions Fulltext Access 36 Pages 2018
Eukaryotic DNA replication: Orchestrated action of multi-subunit protein complexes Fulltext Access 36 Pages 2018
Phase Ib/II study of the pan-cyclin-dependent kinase inhibitor roniciclib in combination with chemotherapy in patients with extensive-disease small-cell lung cancer Fulltext Access 36 Pages 2018
High fat diet-induced obesity exacerbates hematopoiesis deficiency and cytopenia caused by 5-fluorouracil via peroxisome proliferator-activated receptor γ Fulltext Access 36 Pages 2018
Synergistic action of dual IGF1/R and MEK inhibition sensitizes childhood acute lymphoblastic leukemia (ALL) cells to cytotoxic agents and involves downregulation of STAT6 and PDAP1 Fulltext Access 36 Pages 2018
Exosomes derived from imatinib-resistant chronic myeloid leukemia cells mediate a horizontal transfer of drug-resistant trait by delivering miR-365 Fulltext Access 36 Pages 2018
Inhibition of TGF-β pathway reverts extracellular matrix remodeling in T. cruzi-infected cardiac spheroids Fulltext Access 36 Pages 2018
Mitochondria-associated membranes (MAMs): An emerging platform connecting energy and immune sensing to metabolic flexibility Fulltext Access 36 Pages 2018
cAMP/PKA-induced filamin A (FLNA) phosphorylation inhibits SST2 signal transduction in GH-secreting pituitary tumor cells Fulltext Access 36 Pages 2018
Cell therapies for hematological malignancies: don't forget non-gene-modified t cells! Fulltext Access 36 Pages 2018
Impact of Toxicity on Survival for Older Adult Patients after CD34+ Selected Allogeneic Hematopoietic Stem Cell Transplantation Fulltext Access 36 Pages 2018
Haploidentical Stem Cell Transplantation for Refractory/Relapsed Neuroblastoma Fulltext Access 36 Pages 2018
Increased Coexpression of PD-1, TIGIT, and KLRG-1 on Tumor-Reactive CD8+ T Cells During Relapse after Allogeneic Stem Cell Transplantation Fulltext Access 36 Pages 2018
The Hematopoietic Cell Transplant Pharmacist: Roles, Responsibilities, and Recommendations from the ASBMT Pharmacy Special Interest Group Fulltext Access 36 Pages 2018
iPSC-derived neurons of CREBBP- and EP300-mutated Rubinstein-Taybi syndrome patients show morphological alterations and hypoexcitability Fulltext Access 36 Pages 2018
DNA damage in blood cells in relation to chemotherapy and nutritional status in colorectal cancer patients-A pilot study Fulltext Access 36 Pages 2018
Multiple myeloma cells adapted to long-exposure of hypoxia exhibit stem cell characters with TGF-β/Smad pathway activation Fulltext Access 36 Pages 2018
Tannins from Syzygium guineense suppress Wnt signaling and proliferation of Wnt-dependent tumors through a direct effect on secreted Wnts Fulltext Access 36 Pages 2018
The depressed central carbon and energy metabolisms is associated to the acquisition of levofloxacin resistance in Vibrio alginolyticus Fulltext Access 36 Pages 2018
Bioengineering an electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells Fulltext Access 36 Pages 2018
Lanthanide-doped nanoparticles conjugated with an anti-CD33 antibody and a p53-activating peptide for acute myeloid leukemia therapy Fulltext Access 36 Pages 2018
Ultrasound assisted gene and photodynamic synergistic therapy with multifunctional FOXA1-siRNA loaded porphyrin microbubbles for enhancing therapeutic efficacy for breast cancer Fulltext Access 36 Pages 2018
Targeted reversal and phosphorescence lifetime imaging of cancer cell metabolism via a theranostic rhenium(I)-DCA conjugate Fulltext Access 36 Pages 2018
Transfection of gene regulation nanoparticles complexed with pDNA and shRNA controls multilineage differentiation of hMSCs Fulltext Access 36 Pages 2018
A novel Lipidoid-MicroRNA formulation promotes calvarial bone regeneration Fulltext Access 36 Pages 2018
Cyclic peptide-poly(HPMA) nanotubes as drug delivery vectors: In vitro assessment, pharmacokinetics and biodistribution Fulltext Access 36 Pages 2018
pH-sensitive radiolabeled and superfluorinated ultra-small palladium nanosheet as a high-performance multimodal platform for tumor theranostics Fulltext Access 36 Pages 2018
Studying biomineralization pathways in a 3D culture model of breast cancer microcalcifications Fulltext Access 36 Pages 2018
Jade family PHD finger 3 (JADE3) increases cancer stem cell-like properties and tumorigenicity in colon cancer Fulltext Access 36 Pages 2018
Acetyl-l-carnitine is an anti-angiogenic agent targeting the VEGFR2 and CXCR4 pathways Fulltext Access 36 Pages 2018
Oral recombinant methioninase (o-rMETase) is superior to injectable rMETase and overcomes acquired gemcitabine resistance in pancreatic cancer Fulltext Access 36 Pages 2018
Targeting autophagy enhances apatinib-induced apoptosis via endoplasmic reticulum stress for human colorectal cancer Fulltext Access 36 Pages 2018
Piribedil disrupts the MLL1-WDR5 interaction and sensitizes MLL-rearranged acute myeloid leukemia (AML) to doxorubicin-induced apoptosis Fulltext Access 37 Pages 2018
BBI608 inhibits cancer stemness and reverses cisplatin resistance in NSCLC Fulltext Access 37 Pages 2018
Human papilloma virus (HPV) 18 proteins E6 and E7 up-regulate ABC transporters in oropharyngeal carcinoma. Involvement of the nonsense-mediated decay (NMD) pathway Fulltext Access 37 Pages 2018
Tetrandrine inhibits deregulated cell cycle in pancreatic cancer cells: Differential regulation of p21Cip1/Waf1, p27Kip1 and cyclin D1 Fulltext Access 37 Pages 2018
EGFR-TKI-induced HSP70 degradation and BER suppression facilitate the occurrence of the EGFR T790â¯M resistant mutation in lung cancer cells Fulltext Access 37 Pages 2018
Inhibition of MAPKAPK2/MK2 facilitates DNA replication upon cancer cell treatment with gemcitabine but not cisplatin Fulltext Access 37 Pages 2018
Enhanced anti-tumor efficacy of temozolomide-loaded carboxylated poly(amido-amine) combined with photothermal/photodynamic therapy for melanoma treatment Fulltext Access 37 Pages 2018
Extracellular ATP drives breast cancer cell migration and metastasis via S100A4 production by cancer cells and fibroblasts Fulltext Access 37 Pages 2018
The interplay between critical transcription factors and microRNAs in the control of normal and malignant myelopoiesis Fulltext Access 37 Pages 2018
The long noncoding RNA LUCAT1 promotes tumorigenesis by controlling ubiquitination and stability of DNA methyltransferase 1 in esophageal squamous cell carcinoma Fulltext Access 37 Pages 2018
Deferoxamine suppresses esophageal squamous cell carcinoma cell growth via ERK1/2 mediated mitochondrial dysfunction Fulltext Access 37 Pages 2018
Overexpression of MIST1 reverses the epithelial-mesenchymal transition and reduces the tumorigenicity of pancreatic cancer cells via the Snail/E-cadherin pathway Fulltext Access 37 Pages 2018
MT-ND5 Mutation Exhibits Highly Variable Neurological Manifestations at Low Mutant Load Fulltext Access 37 Pages 2018
Sulforaphane-N-Acetyl-Cysteine inhibited autophagy leading to apoptosis via Hsp70-mediated microtubule disruption Fulltext Access 37 Pages 2018
Fucoidan upregulates TLR4/CHOP-mediated caspase-3 and PARP activation to enhance cisplatin-induced cytotoxicity in human lung cancer cells Fulltext Access 37 Pages 2018
Suppression of ribosomal protein RPS6KB1 by Nexrutine increases sensitivity of prostate tumors to radiation Fulltext Access 37 Pages 2018
Methylation-mediated miR-155-FAM133A axis contributes to the attenuated invasion and migration of IDH mutant gliomas Fulltext Access 37 Pages 2018
Experimental and integrative analyses identify an ETS1 network downstream of BCR-ABL in chronic myeloid leukemia (CML) Fulltext Access 37 Pages 2018