At the pulse of time: protein interactions determine the pace of circadian clocks Fulltext Access 7 Pages 2005
Protonation state of Asp30 exerts crucial influence over surface loop rearrangements responsible for NO release in nitrophorin 4 Fulltext Access 7 Pages 2005
Structural basis for recognition of ubiquitinated cargo by Tom1-GAT domain Fulltext Access 7 Pages 2005
Phosphorylation of cold shock domain/Y-box proteins by ERK2 and GSK3β and repression of the human VEGF promoter Fulltext Access 7 Pages 2005
The Drosophila homologue of the dystrophin gene – Introns containing promoters are the major contributors to the large size of the gene Fulltext Access 7 Pages 2005
Glucose deprivation mediates interaction between CTDK-I and Snf1 in Saccharomyces cerevisiae Fulltext Access 7 Pages 2005
The verprolin family of proteins: Regulators of cell morphogenesis and endocytosis Fulltext Access 7 Pages 2005
Understanding the enzymology of fibrinolysis and improving thrombolytic therapy Fulltext Access 7 Pages 2005
Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract Fulltext Access 7 Pages 2005
Role of sodium in mitochondrial membrane depolarization induced by P2X7 receptor activation in submandibular glands Fulltext Access 7 Pages 2005
The regulation of proteasome degradation by multi-ubiquitin chain binding proteins Fulltext Access 7 Pages 2005
A crevice adjoining the ribosome tunnel: Hints for cotranslational folding Fulltext Access 7 Pages 2005
cda1+, encoding chitin deacetylase is required for proper spore formation in Schizosaccharomyces pombe Fulltext Access 7 Pages 2005
Purkinje-cell degeneration in prion protein-deficient mice is associated with a cerebellum-specific Doppel protein species signature Fulltext Access 7 Pages 2005
Long CGG-repeat tracts are toxic to human cells: Implications for carriers of Fragile X premutation alleles Fulltext Access 7 Pages 2005
Oligomerization and assembly of the matrix protein of Borna disease virus Fulltext Access 7 Pages 2005
Molecular basis of the allosteric mechanism of cAMP in the regulatory PKA subunit Fulltext Access 7 Pages 2005
Distribution profile of inositol 1,4,5-trisphosphate receptor isoforms in adrenal chromaffin cells Fulltext Access 7 Pages 2005
Transcriptional regulation of connective tissue growth factor by sphingosine 1-phosphate in rat cultured mesangial cells Fulltext Access 7 Pages 2005
Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium Fulltext Access 7 Pages 2005
Specific inhibition of HIV-1 replication by short hairpin RNAs targeting human cyclin T1 without inducing apoptosis Fulltext Access 7 Pages 2005
PTEN expression in ovine granulosa cells increases during terminal follicular growth Fulltext Access 7 Pages 2005
Involvement of matrix metalloproteinase-9 in platelet-activating factor-induced angiogenesis Fulltext Access 7 Pages 2005
Human mitochondrial peroxiredoxin 5 protects from mitochondrial DNA damages induced by hydrogen peroxide Fulltext Access 7 Pages 2005
The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs Fulltext Access 7 Pages 2005
Effect of EPS1 gene deletion in Saccharomyces cerevisiae on the secretion of foreign proteins which have disulfide bridges Fulltext Access 7 Pages 2005
Water and molecular chaperones act as weak links of protein folding networks: Energy landscape and punctuated equilibrium changes point towards a game theory of proteins Fulltext Access 7 Pages 2005
Adiponectin is synthesized and secreted by human and murine cardiomyocytes Fulltext Access 7 Pages 2005
Subcellular distribution of chromogranins A and B in bovine adrenal chromaffin cells Fulltext Access 7 Pages 2005
Microsomal triglyceride transfer protein expression in adipocytes: A new component in fat metabolism Fulltext Access 7 Pages 2005
Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in growth hormone treated animals Fulltext Access 7 Pages 2005
Peroxynitrite-mediated matrix metalloproteinase-2 activation in human hepatic stellate cells Fulltext Access 7 Pages 2005
CysMap and CysJoin: Database and tools for protein disulphides localisation Fulltext Access 7 Pages 2005
Nitric oxide mediates anti-inflammatory action of extracorporeal shock waves Fulltext Access 7 Pages 2005
Identification of the novel evolutionary conserved obstructor multigene family in invertebrates Fulltext Access 7 Pages 2005
A genome-wide expression profile and system-level integration of nuclear factor kappa B regulated genes reveals fundamental metabolic adaptations during cell growth and survival Fulltext Access 7 Pages 2005
ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes Fulltext Access 7 Pages 2005
The binding of mycolic acids to galectin-3: A novel interaction between a host soluble lectin and trafficking mycobacterial lipids? Fulltext Access 7 Pages 2005
Identification of multiple allosteric sites on the M1 muscarinic acetylcholine receptor Fulltext Access 7 Pages 2005
Epac1 regulates integrity of endothelial cell junctions through VE-cadherin Fulltext Access 7 Pages 2005
Hypertonic sodium chloride induction of cyclooxygenase-2 occurs independently of NF-κB and is inhibited by the glucocorticoid receptor in A549 cells Fulltext Access 7 Pages 2005
PACAP protects neuronal differentiated PC12 cells against the neurotoxicity induced by a mitochondrial complex I inhibitor, rotenone Fulltext Access 7 Pages 2005
Nitrite as the major source of nitric oxide production by Arabidopsis thaliana in response to Pseudomonas syringae Fulltext Access 7 Pages 2005
Identification of a villin-related tobacco protein as a novel cross-reactive plant allergen Fulltext Access 7 Pages 2005
Mutations in the NDUFS4 gene of mitochondrial complex I alter stability of the splice variants Fulltext Access 7 Pages 2005
Ceramide-1-phosphate promotes cell survival through activation of the phosphatidylinositol 3-kinase/protein kinase B pathway Fulltext Access 7 Pages 2005
Sp1 elements in SULT2B1b promoter and 5′-untranslated region of mRNA: Sp1/Sp2 induction and augmentation by histone deacetylase inhibition Fulltext Access 7 Pages 2005
Role of the PDK1–PKB–GSK3 pathway in regulating glycogen synthase and glucose uptake in the heart Fulltext Access 7 Pages 2005
Disulfide-bond formation in the H+-pyrophosphatase of Streptomyces coelicolor and its implications for redox control and enzyme structure Fulltext Access 7 Pages 2005
Purification and functional reconstitution of the human Wilson copper ATPase, ATP7B Fulltext Access 7 Pages 2005
Cry11Aa toxin from Bacillus thuringiensis binds its receptor in Aedes aegypti mosquito larvae through loop α-8 of domain II Fulltext Access 7 Pages 2005
ALK5 and Smad4 are involved in TGF-β1-induced pulmonary endothelial permeability Fulltext Access 7 Pages 2005
Alternative splicing regulates the transcriptional activity of Drosophila heat shock transcription factor in response to heat/cold stress Fulltext Access 7 Pages 2005
The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment Fulltext Access 7 Pages 2005
Interleukin-4 downregulates TNFα-induced IL-8 production in keratinocytes Fulltext Access 7 Pages 2005
Suppressors of RNA silencing encoded by plant viruses and their role in viral infections Fulltext Access 7 Pages 2005
Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1 Fulltext Access 7 Pages 2005
Transgenic tobacco plants overexpressing glyoxalase enzymes resist an increase in methylglyoxal and maintain higher reduced glutathione levels under salinity stress Fulltext Access 7 Pages 2005
Nitric oxide induces tau hyperphosphorylation via glycogen synthase kinase-3β activation Fulltext Access 7 Pages 2005
Synthesis of (di)nucleoside polyphosphates by the ubiquitin activating enzyme E1 Fulltext Access 7 Pages 2005
Identification and analysis of Hic-5/ARA55 isoforms: Implications for integrin signaling and steroid hormone action Fulltext Access 7 Pages 2005
Nucleotide binding to the homodimeric MJ0796 protein: A computational study of a prokaryotic ABC transporter NBD dimer Fulltext Access 7 Pages 2005
ASF/SF2 and SC35 regulate the glutamate receptor subunit 2 alternative flip/flop splicing Fulltext Access 7 Pages 2005
Functional replacement of Drosophila Btk29A with human Btk in male genital development and survival Fulltext Access 7 Pages 2005
Regulation of lipopolysaccharide-induced inflammatory response by glutathione S-transferase P1 in RAW264.7 cells Fulltext Access 7 Pages 2005
ZD1839 (Gefitinib, ‘Iressa’), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma Fulltext Access 7 Pages 2005
Grifolin, a potential antitumor natural product from the mushroom Albatrellus confluens, inhibits tumor cell growth by inducing apoptosis in vitro Fulltext Access 7 Pages 2005
Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase Fulltext Access 7 Pages 2005
A genome-wide analysis of sumoylation-related biological processes and functions in human nucleus Fulltext Access 7 Pages 2005
Novel type aquaporin SIPs are mainly localized to the ER membrane and show cell-specific expression in Arabidopsis thaliana Fulltext Access 7 Pages 2005
Identification and characterization of rDJL, a novel member of the DnaJ protein family, in rat testis Fulltext Access 7 Pages 2005
The Saccharomyces cerevisiae Ca2+ channel Cch1pMid1p is essential for tolerance to cold stress and iron toxicity Fulltext Access 7 Pages 2005
The “resurrection method” for modification of specific proteins in higher plants Fulltext Access 7 Pages 2005
Single chain antibody against the common epitope of mutant p53 restores wild-type activity to mutant p53 protein Fulltext Access 7 Pages 2005
The effects of partial thiamin deficiency and oxidative stress (i.e., glyoxal and methylglyoxal) on the levels of α-oxoaldehyde plasma protein adducts in Fischer 344 rats Fulltext Access 7 Pages 2005
ADAM12-mediated focal adhesion formation is differently regulated by β1 and β3 integrins Fulltext Access 7 Pages 2005
The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase Fulltext Access 7 Pages 2005
Validating the use of database potentials in protein structure determination by NMR Fulltext Access 7 Pages 2005
Progesterone inhibits human breast cancer cell growth through transcriptional upregulation of the cyclin-dependent kinase inhibitor p27Kip1 gene Fulltext Access 7 Pages 2005
Selective activation of adrenergic β1 receptors induces heme oxygenase 1 production in RAW264.7 cells Fulltext Access 7 Pages 2005
Inhibition of matrix metalloproteinase-9 by interferons and TGF-β1 through distinct signalings accounts for reduced monocyte invasiveness Fulltext Access 7 Pages 2005
Analysis of glycoside hydrolase family 98: Catalytic machinery, mechanism and a novel putative carbohydrate binding module Fulltext Access 7 Pages 2005
Characterization of the DNA-binding site in the ferric uptake regulator protein from Escherichia coli by UV crosslinking and mass spectrometry Fulltext Access 7 Pages 2005
An archaeal SET domain protein exhibits distinct lysine methyltransferase activity towards DNA-associated protein MC1-α Fulltext Access 7 Pages 2005