Novel immunotoxin: A fusion protein consisting of gelonin and an acetylcholine receptor fragment as a potential immunotherapeutic agent for the treatment of Myasthenia gravis Fulltext Access 12 Pages 2006
The Crystal Structure of the Rare-Cutting Restriction Enzyme SdaI Reveals Unexpected Domain Architecture Fulltext Access 12 Pages 2006
Crystal Structure of Ethylbenzene Dehydrogenase from Aromatoleum aromaticum Fulltext Access 12 Pages 2006
Lengsin Is a Survivor of an Ancient Family of Class I Glutamine Synthetases Re-engineered by Evolution for a Role in the Vertebrate Lens Fulltext Access 12 Pages 2006
Glucocorticoids stimulate the activity of large-conductance Ca2+-activated K+ channels in pituitary GH3 and AtT-20 cells via a non-genomic mechanism Fulltext Access 12 Pages 2006
Molecular docking simulations of steroid substrates into human cytosolic hydroxysteroid dehydrogenases (AKR1C1 and AKR1C2): Insights into positional and stereochemical preferences Fulltext Access 12 Pages 2006
The metabolism of cholesterol and certain hormonal steroids by Treponema denticola Fulltext Access 12 Pages 2006
Analysis of derivatised steroids by matrix-assisted laser desorption/ionisation and post-source decay mass spectrometry Fulltext Access 12 Pages 2006
Chemical synthesis of the 3-sulfooxy-7-N-acetylglucosaminyl-24-amidated conjugates of 3β,7β-dihydroxy-5-cholen-24-oic acid, and related compounds: Unusual, major metabolites of bile acid in a patient with Niemann-Pick disease type C1 Fulltext Access 12 Pages 2006
Three-dimensional models of non-steroidal ligands: A comparative molecular field analysis Fulltext Access 12 Pages 2006
Synthesis of putative metabolites of 1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (ED-71) Fulltext Access 12 Pages 2006
In vitro expression and characterization of native apomyoglobin under low molecular crowding conditions Fulltext Access 12 Pages 2006
Complete Reaction Cycle of a Cocaine Catalytic Antibody at Atomic Resolution Fulltext Access 12 Pages 2006
Expression of the human activin type I and II receptor extracellular domains in Pichia pastoris Fulltext Access 12 Pages 2006
Expression, purification, and characterization of Clostridium botulinum type B light chain Fulltext Access 12 Pages 2006
Alkaline phytase from Lilium longiflorum: Purification and structural characterization Fulltext Access 12 Pages 2006
High-throughput identification of refolding conditions for LXRβ without a functional assay Fulltext Access 12 Pages 2006
In vitro reconstitution and preparative purification of complexes between the chemokine receptor CXCR4 and its ligands SDF-1α, gp120–CD4 and AMD3100 Fulltext Access 12 Pages 2006
Nitric oxide production from rat adipocytes is modulated by β3-adrenergic receptor agonists and is involved in a cyclic AMP-dependent lipolysis in adipocytes Fulltext Access 12 Pages 2006
Specific amino acid residues in the β sliding clamp establish a DNA polymerase usage hierarchy in Escherichia coli Fulltext Access 12 Pages 2006
Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations Fulltext Access 12 Pages 2006
Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations Fulltext Access 12 Pages 2006
Transpositions and translocations induced by site-specific double-strand breaks in budding yeast Fulltext Access 12 Pages 2006
De Novo Tubular Nanostructure Design Based on Self-Assembly of β-Helical Protein Motifs Fulltext Access 12 Pages 2006
Molecular characterization of a new scorpion venom lipolysis activating peptide: Evidence for disulfide bridge-mediated functional switch of peptides Fulltext Access 12 Pages 2006
Dynamics of 23Na during completely balanced steady-state free precession Fulltext Access 12 Pages 2006
Faithful estimation of dynamics parameters from CPMG relaxation dispersion measurements Fulltext Access 12 Pages 2006
Optimum spin-state selection for all multiplicities in the acquisition dimension of the HSQC experiment Fulltext Access 12 Pages 2006
Steady-state free precession with hyperpolarized 3He: Experiments and theory Fulltext Access 12 Pages 2006
Relationship between susceptibility induced field inhomogeneities, restricted diffusion, and relaxation in sedimentary rocks Fulltext Access 12 Pages 2006
1H-13C INEPT MAS NMR correlation experiments with 1H-1H mediated magnetization exchange to probe organization in lipid biomembranes Fulltext Access 12 Pages 2006
Combined passive and active shimming for in vivo MR spectroscopy at high magnetic fields Fulltext Access 12 Pages 2006
Dynamic analysis of a genomic island in Magnetospirillum sp. strain AMB-1 reveals how magnetosome synthesis developed Fulltext Access 12 Pages 2006
Flexible Fitting in 3D-EM Guided by the Structural Variability of Protein Superfamilies Fulltext Access 12 Pages 2006
Molecular Mechanism for the Regulation of Rho-Kinase by Dimerization and Its Inhibition by Fasudil Fulltext Access 12 Pages 2006
Solution Structure of the SWIRM Domain of Human Histone Demethylase LSD1 Fulltext Access 12 Pages 2006
Conformational Diversity in the TPR Domain-Mediated Interaction of Protein Phosphatase 5 with Hsp90 Fulltext Access 12 Pages 2006
The Structure of a Ketoreductase Determines the Organization of the β-Carbon Processing Enzymes of Modular Polyketide Synthases Fulltext Access 12 Pages 2006
The Structure of I-CeuI Homing Endonuclease: Evolving Asymmetric DNA Recognition from a Symmetric Protein Scaffold Fulltext Access 12 Pages 2006
Assessing Computational Amino Acid β-Turn Propensities with a Phage-Displayed Combinatorial Library and Directed Evolution Fulltext Access 12 Pages 2006
An Expanded Conformation of Single-Ring GroEL-GroES Complex Encapsulates an 86 kDa Substrate Fulltext Access 12 Pages 2006
Structure and Interactions at the Viral Surface of the Envelope Protein E1 of Semliki Forest Virus Fulltext Access 12 Pages 2006
Crystal Structure of the Human Retinitis Pigmentosa 2 Protein and Its Interaction with Arl3 Fulltext Access 12 Pages 2006
A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain α-Ketoacid Dehydrogenase Fulltext Access 12 Pages 2006
Cooperative unfolding of Escherichia coli ribosome recycling factor originating from its domain–domain interaction and its implication for function Fulltext Access 12 Pages 2006
HESR1/CHF2 suppresses VEGFR2 transcription independent of binding to E-boxes Fulltext Access 12 Pages 2006
Internalization of CD40 regulates its signal transduction in vascular endothelial cells Fulltext Access 12 Pages 2006
Comprehensive comparisons of the current human, mouse, and rat RefSeq, Ensembl, EST, and FANTOM3 datasets: Identification of new human genes with specific tissue expression profile Fulltext Access 12 Pages 2006
Crystal structure of rubredoxin from Desulfovibrio gigas to ultra-high 0.68 Å resolution Fulltext Access 12 Pages 2006
The rat Tspy is preferentially expressed in elongated spermatids and interacts with the core histones Fulltext Access 12 Pages 2006
Bcl-2 but not clusterin/apolipoprotein J protected human diploid fibroblasts and immortalized keratinocytes from ceramide-induced apoptosis: Role of p53 in the ceramide response Fulltext Access 12 Pages 2006
Homocysteine transport by human aortic endothelial cells: Identification and properties of import systems Fulltext Access 12 Pages 2006
The LTR promoter of the rat oncomodulin gene is regulated by cell-line specific accessibility in the LTR U3 region Fulltext Access 12 Pages 2006
Conformational lability of two molecular chaperones Hsc70 and gp96: Effects of pH and temperature Fulltext Access 12 Pages 2006
Effect of experimental and cold exposure induced hyperthyroidism on H2O2 production and susceptibility to oxidative stress of rat liver mitochondria Fulltext Access 12 Pages 2006
Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1 Fulltext Access 12 Pages 2006
Thrombin induces neurodegeneration and microglial activation in the cortex in vivo and in vitro: Proteolytic and non-proteolytic actions Fulltext Access 12 Pages 2006
Intracellular pathways of folded and misfolded amyloid precursor protein degradation Fulltext Access 12 Pages 2006
Cloning, expression, purification and characterization of recombinant (+)-germacrene D synthase from Zingiber officinale Fulltext Access 12 Pages 2006
Limited sensitivity of pigment photo-oxidation in isolated thylakoids to singlet excited state quenching in photosystem II antenna Fulltext Access 12 Pages 2006
The effects of the flavonoid baicalein and osmolytes on the Mg 2+ accelerated aggregation/fibrillation of carboxymethylated bovine 1SS-α-lactalbumin Fulltext Access 12 Pages 2006
GPS, the slope of laurdan generalized polarization spectra, in the study of phospholipid lateral organization and Escherichia coli lipid phases Fulltext Access 12 Pages 2006
Identification of a pre-mRNA splicing factor, arginine/serine-rich 3 (Sfrs3), and its co-expression with fibronectin in fetal and postnatal rabbit airway mucosal and skin wounds ★ Fulltext Access 12 Pages 2006
The importance and identification of regulatory polymorphisms and their mechanisms of action Fulltext Access 12 Pages 2006
Anti-amyloidogenic effects of antioxidants: Implications for the prevention and therapeutics of Alzheimer's disease Fulltext Access 12 Pages 2006
Adhesion contact kinetics of HepG2 cells during Hepatitis B virus replication: Involvement of SH3-binding motif in HBX Fulltext Access 12 Pages 2006
Molecular characterization and localization of Plasmodium falciparum choline kinase Fulltext Access 12 Pages 2006
Identification and distribution of heparan sulfate proteoglycans in the white muscle of Atlantic cod (Gadus morhua) and spotted wolffish (Anarhichas minor) Fulltext Access 12 Pages 2006
Characterization of cDNAs encoding cholesterol side chain cleavage and 3β-hydroxysteroid dehydrogenase in the freshwater stingray Potamotrygon motoro Fulltext Access 12 Pages 2006
Identification of low molecular weight molecules as new components of the nacre organic matrix Fulltext Access 12 Pages 2006
The effects of chronic immune stimulation on muscle growth in rainbow trout Fulltext Access 12 Pages 2006
Stress protein response in two sibling species of Marenzelleria (Polychaeta: Spionidae): Is there an influence of acclimation salinity? Fulltext Access 12 Pages 2006
Astacin family metallopeptidases and serine peptidase inhibitors in spider digestive fluid Fulltext Access 12 Pages 2006
FABP3 and FABP10 in Atlantic salmon (Salmo salar L.)- General effects of dietary fatty acid composition and life cycle variations Fulltext Access 12 Pages 2006
Diversity of digestive proteinases in Tenebrio molitor (Coleoptera: Tenebrionidae) larvae Fulltext Access 12 Pages 2006
Morphometry, ultrastructure, myosin isoforms, and metabolic capacities of the “mini muscles” favoured by selection for high activity in house mice Fulltext Access 12 Pages 2006
Solubilization, purification and reconstitution of Ca2+-ATPase from bovine pulmonary artery smooth muscle microsomes by different detergents: Preservation of native structure and function of the enzyme by DHPC Fulltext Access 12 Pages 2006
Structural differences between TSEs strains investigated by FT-IR spectroscopy Fulltext Access 12 Pages 2006
Biophysical characteristics of neurotensin polyplex for in vitro and in vivo gene transfection Fulltext Access 12 Pages 2006
Biochemical characterization of a low molecular weight aspartic protease inhibitor from thermo-tolerant Bacillus licheniformis: Kinetic interactions with Pepsin Fulltext Access 12 Pages 2006
Effects of molecular size and chemical structure on renal and hepatic removal of exogenously administered chondroitin sulfate in rats Fulltext Access 12 Pages 2006
Bioelectrocatalytic properties of lignin peroxidase from Phanerochaete chrysosporium in reactions with phenols, catechols and lignin-model compounds Fulltext Access 12 Pages 2006
Localization of Rheb to the endomembrane is critical for its signaling function Fulltext Access 12 Pages 2006
Identification of FUSE-binding proteins as interacting partners of TIA proteins Fulltext Access 12 Pages 2006
Nuclear localization of coactivator RAC3 is mediated by a bipartite NLS and importin α3 Fulltext Access 12 Pages 2006
Molecular characterization and evidencing of the porcine CRH gene as a functional-positional candidate for growth and body composition Fulltext Access 12 Pages 2006
Inhibition of calmodulin-dependent cyclic AMP phosphodiesterase by phenoxazines Fulltext Access 12 Pages 2006
Alteration of familial ALS-linked mutant SOD1 solubility with disease progression: Its modulation by the proteasome and Hsp70 Fulltext Access 12 Pages 2006
Selective cleavage of heparin using aqueous 2-hydroxypyridine: Production of an aldose-terminating fragment with high anticoagulant activity Fulltext Access 12 Pages 2006