Allosteric Communication Network in the Tetrameric Restriction Endonuclease Bse634I Fulltext Access 13 Pages 2006
PARP-1 Interaction with VP1 Capsid Protein Regulates Polyomavirus Early Gene Expression†† Fulltext Access 13 Pages 2006
HACA, the transcriptional activator of the unfolded protein response (UPR) in Aspergillus niger, binds to partly palindromic UPR elements of the consensus sequence 5′-CAN(G/A)NTGT/GCCT-3′ Fulltext Access 13 Pages 2006
Light regulation of asexual development in the rice blast fungus, Magnaporthe oryzae Fulltext Access 13 Pages 2006
A phosphoglucose isomerase mutant in Aspergillus nidulans is defective in hyphal polarity and conidiation Fulltext Access 13 Pages 2006
Mating type gene analysis in apparently asexual Cercospora species is suggestive of cryptic sex Fulltext Access 13 Pages 2006
Split marker transformation increases homologous integration frequency in Cryptococcus neoformans Fulltext Access 13 Pages 2006
A cDNA-AFLP based strategy to identify transcripts associated with avirulence in Phytophthora infestans Fulltext Access 13 Pages 2006
G-protein and cAMP-mediated signaling in aspergilli: A genomic perspective Fulltext Access 13 Pages 2006
Differential distribution of the endoplasmic reticulum network as visualized by the BipA–EGFP fusion protein in hyphal compartments across the septum of the filamentous fungus, Aspergillus oryzae Fulltext Access 13 Pages 2006
Global gene expression during nitrogen starvation in the rice blast fungus, Magnaporthe grisea Fulltext Access 13 Pages 2006
Iron Incorporation in Streptococcus suis Dps-like Peroxide Resistance Protein Dpr Requires Mobility in the Ferroxidase Center and Leads to the Formation of a Ferrihydrite-like Core Fulltext Access 13 Pages 2006
Children's exposure to environmental pollutants and biomarkers of genetic damage: I. Overview and critical issues Fulltext Access 13 Pages 2006
Evaluation of new 2,2â²-dimethyl-5,5â²-dipropoxybenzidine- and 3,3â²-dipropoxybenzidine-based direct dye analogs for mutagenic activity by use of the Salmonella/mammalian mutagenicity assay Fulltext Access 13 Pages 2006
Development of genotoxicity test procedures with Episkin®, a reconstructed human skin model: Towards new tools for in vitro risk assessment of dermally applied compounds? Fulltext Access 13 Pages 2006
Dacarbazine induces genotoxic and cytotoxic germ cell damage with concomitant decrease in testosterone and increase in lactate dehydrogenase concentration in the testis Fulltext Access 13 Pages 2006
Development of a method for assessing micronucleus induction in a 3D human skin model (EpiDerm™) Fulltext Access 13 Pages 2006
DNA intercalative potential of marketed drugs testing positive in in vitro cytogenetics assays Fulltext Access 13 Pages 2006
Oxidative stress and genotoxic effects in gill and kidney of Anguilla anguilla L. exposed to chromium with or without pre-exposure to β-naphthoflavone Fulltext Access 13 Pages 2006
Nutritional supplement chromium picolinate generates chromosomal aberrations and impedes progeny development in Drosophila melanogaster Fulltext Access 13 Pages 2006
Escherichia coli DNA polymerase II can efficiently bypass 3,N4-ethenocytosine lesions in vitro and in vivo Fulltext Access 13 Pages 2006
2- and 4-Aminobiphenyls induce oxidative DNA damage in human hepatoma (Hep G2) cells via different mechanisms Fulltext Access 13 Pages 2006
Fructose-1,6-bisphosphatase mediates cellular responses to DNA damage and aging in Saccharomyces cerevisiae Fulltext Access 13 Pages 2006
Ultra-high Resolution Crystal Structure of HIV-1 Protease Mutant Reveals Two Binding Sites for Clinical Inhibitor TMC114 Fulltext Access 13 Pages 2006
Crystal Structure and Nucleotide Binding of the Thermus thermophilus RNA Helicase Hera N-terminal Domain Fulltext Access 13 Pages 2006
Amino-terminal Domain Stability Mediates Apolipoprotein E Aggregation into Neurotoxic Fibrils Fulltext Access 13 Pages 2006
Discoidin Domain Receptor 2 Inhibits Fibrillogenesis of Collagen Type 1 Fulltext Access 13 Pages 2006
blm3-1 Is an Allele of UBP3, a Ubiquitin Protease that Appears to Act During Transcription of Damaged DNA Fulltext Access 13 Pages 2006
Suppression of HIV-1 Protease Inhibitor Resistance by Phosphonate-mediated Solvent Anchoring Fulltext Access 13 Pages 2006
Engineered Extrahelical Base Destabilization Enhances Sequence Discrimination of DNA Methyltransferase M.HhaI Fulltext Access 13 Pages 2006
Crystal Structure and Mechanism of Tripeptidyl Activity of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis Fulltext Access 13 Pages 2006
A Tandem of SH3-like Domains Participates in RNA Binding in KIN17, a Human Protein Activated in Response to Genotoxics Fulltext Access 13 Pages 2006
SOS Repair and DNA Supercoiling Influence the Genetic Stability of DNA Triplet Repeats in Escherichia coli Fulltext Access 13 Pages 2006
Selective Binding of Meiosis-specific Yeast Hop1 Protein to the Holliday Junctions Distorts the DNA Structure and Its Implications for Junction Migration and Resolution Fulltext Access 13 Pages 2006
Structure of Leishmania mexicana Phosphomannomutase Highlights Similarities with Human Isoforms Fulltext Access 13 Pages 2006
NMR-based Model Reveals the Structural Determinants of Mammalian Arylamine N-Acetyltransferase Substrate Specificity Fulltext Access 13 Pages 2006
Molecular genetic alterations of FHIT and p53 genes in benign and malignant thyroid gland lesions Fulltext Access 13 Pages 2006
PAS Domain Allostery and Light-induced Conformational Changes in Photoactive Yellow Protein upon I2 Intermediate Formation, Probed with Enhanced Hydrogen/Deuterium Exchange Mass Spectrometry Fulltext Access 13 Pages 2006
Xenobiotic Reductase A in the Degradation of Quinoline by Pseudomonas putida 86: Physiological Function, Structure and Mechanism of 8-Hydroxycoumarin Reduction Fulltext Access 13 Pages 2006
The Structure of Bovine Complement Component 3 Reveals the Basis for Thioester Function Fulltext Access 13 Pages 2006
Non-nucleoside Inhibitors Binding to Hepatitis C Virus NS5B Polymerase Reveal a Novel Mechanism of Inhibition Fulltext Access 13 Pages 2006
Translation Initiation Factor IF2 Interacts with the 30 S Ribosomal Subunit via Two Separate Binding Sites Fulltext Access 13 Pages 2006
Sequence Motifs and Antimotifs in β-Barrel Membrane Proteins from a Genome-Wide Analysis: The Ala-Tyr Dichotomy and Chaperone Binding Motifs Fulltext Access 13 Pages 2006
Engineering, Biophysical Characterisation and Binding Properties of a Soluble Mutant form of Annexin A2 Domain IV that Adopts a Partially Folded Conformation Fulltext Access 13 Pages 2006
Dcs2, a Novel Stress-induced Modulator of m7GpppX Pyrophosphatase Activity that Locates to P Bodies Fulltext Access 13 Pages 2006
Characterization of the Reactivity Determinants of a Novel Hairpin Substrate of Yeast RNase III Fulltext Access 13 Pages 2006
Natural Selection for Kinetic Stability Is a Likely Origin of Correlations between Mutational Effects on Protein Energetics and Frequencies of Amino Acid Occurrences in Sequence Alignments Fulltext Access 13 Pages 2006
CD40 mediated human cholangiocyte apoptosis requires JAK2 dependent activation of STAT3 in addition to activation of JNK1/2 and ERK1/2 Fulltext Access 13 Pages 2006
Two different stages of epidermal growth factor (EGF) receptor endocytosis are sensitive to free ubiquitin depletion produced by proteasome inhibitor MG132 Fulltext Access 13 Pages 2006
αII-Spectrin interacts with five groups of functionally important proteins in the nucleus Fulltext Access 13 Pages 2006
Modulation of the epithelial barrier by dexamethasone and prolactin in cultured Madin-Darby canine kidney (MDCK) cells Fulltext Access 13 Pages 2006
Visualization of the chromosome scaffold and intermediates of loop domain compaction in extracted mitotic cells Fulltext Access 13 Pages 2006
P2Y12 receptor signalling towards PKB proceeds through IGF-I receptor cross-talk and requires activation of Src, Pyk2 and Rap1 Fulltext Access 13 Pages 2006
PKCη is localized in the Golgi, ER and nuclear envelope and translocates to the nuclear envelope upon PMA activation and serum-starvation: Fulltext Access 13 Pages 2006
Functional mapping and identification of novel regulators for the Toll/Interleukin-1 signalling network by transcription expression cloning Fulltext Access 13 Pages 2006
Cytokine Gene Expression in Peripheral Blood Mononuclear Cells and Alloreactivity in Hematopoietic Cell Transplantation with Nonmyeloablative Conditioning Fulltext Access 13 Pages 2006
Death or survival: Membrane ceramide controls the fate and activation of antigen-specific T-cells depending on signal strength and duration Fulltext Access 13 Pages 2006
EGFR signaling leads to downregulation of PTP-LAR via TACE-mediated proteolytic processing Fulltext Access 13 Pages 2006
TGF-β regulates differentially the proliferation of fetal and adult human skin fibroblasts via the activation of PKA and the autocrine action of FGF-2 Fulltext Access 13 Pages 2006
Role of c-KIT expression level and phosphatidylinositol 3-kinase activation in survival and proliferative responses of early myeloid cells Fulltext Access 13 Pages 2006
RGS proteins have a signalling complex: Interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins Fulltext Access 13 Pages 2006
Activation of Gab1 in pancreatic acinar cells: Effects of gastrointestinal growth factors/hormones on stimulation, phosphospecific phosphorylation, translocation and interaction with downstream signaling molecules Fulltext Access 13 Pages 2006
Phosphoproteomic profiling of human SH-SY5Y neuroblastoma cells during response to 6-hydroxydopamine-induced oxidative stress Fulltext Access 13 Pages 2006
S100A1-deficient male mice exhibit increased exploratory activity and reduced anxiety-related responses Fulltext Access 13 Pages 2006
Species-specific cell–matrix interactions are essential for differentiation of alveoli like structures and milk gene expression in primary mammary cells of the Cape fur seal (Arctocephalus pusillus pusillus) Fulltext Access 13 Pages 2006
Heparan sulfate proteoglycans including syndecan-3 modulate BMP activity during limb cartilage differentiation Fulltext Access 13 Pages 2006
Sequences and domain structures of mammalian, avian, amphibian and teleost tropoelastins: Clues to the evolutionary history of elastins Fulltext Access 13 Pages 2006
Regulation of serine protease inhibitor-E2 and plasminogen activator expression and secretion by follicle stimulating hormone and growth factors in non-luteinizing bovine granulosa cells in vitro Fulltext Access 13 Pages 2006
The role of Rac1 in maintaining malignant phenotype of mouse skin tumor cells Fulltext Access 13 Pages 2006
Growth inhibition and induction of apoptosis in MCF-7 breast cancer cells by Antrodia camphorata Fulltext Access 13 Pages 2006
Histone deacetylase inhibitors require caspase activity to induce apoptosis in lung and prostate carcinoma cells Fulltext Access 13 Pages 2006
Organ-specific susceptibility of p53 knockout mice to N-bis(2-hydroxypropyl)nitrosamine carcinogenesis Fulltext Access 13 Pages 2006
A cDNA-microarray analysis of camptothecin resistance in glioblastoma cell lines Fulltext Access 13 Pages 2006
Correction of malignant behavior of tumor cells by traditional Chinese herb medicine through a restoration of p53 Fulltext Access 13 Pages 2006
Methionine-stress: A pleiotropic approach in enhancing the efficacy of chemotherapy Fulltext Access 13 Pages 2006
Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis Fulltext Access 13 Pages 2006
New perspectives on the role of SERCA2's Ca2+ affinity in cardiac function Fulltext Access 13 Pages 2006
Differential effects of Stat3 inhibition in sparse vs confluent normal and breast cancer cells Fulltext Access 13 Pages 2006
The expression and functional characterization of sigma (σ) 1 receptors in breast cancer cell lines Fulltext Access 13 Pages 2006
Distribution of breakpoints on chromosome 18 in breast, colorectal, and pancreatic carcinoma cell lines Fulltext Access 13 Pages 2006
Molecular cytogenetic profiling of complex karyotypes in primary myelodysplastic syndromes and acute myeloid leukemia Fulltext Access 13 Pages 2006
Cytogenetic studies of a series of 43 consecutive secondary myelodysplastic syndromes/acute myeloid leukemias: conventional cytogenetics, FISH, and multiplex FISH Fulltext Access 13 Pages 2006
Pretransplantation Consolidation Chemotherapy Decreases Leukemia Relapse after Autologous Blood and Bone Marrow Transplants for Acute Myelogenous Leukemia in First Remission Fulltext Access 13 Pages 2006
RNA Loading of Leukemic Antigens into Cord Blood–Derived Dendritic Cells for Immunotherapy Fulltext Access 13 Pages 2006
Role of Allogeneic Stem Cell Transplantation for Adult Chronic Myeloid Leukemia in the Imatinib Era Fulltext Access 13 Pages 2006