Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins: Their reactivities in solid-phase and cell assays and conformational analysis by molecular dynamics simulations Fulltext Access 13 Pages 2006
Identification of 4-amino-2-cyclohexylaminoquinazolines as metabolically stable melanin-concentrating hormone receptor 1 antagonists Fulltext Access 13 Pages 2006
Dose-dependent antithrombotic activity of an orally active tissue factor/factor VIIa inhibitor without concomitant enhancement of bleeding propensity Fulltext Access 13 Pages 2006
A new structural theme in C2-symmetric HIV-1 protease inhibitors: ortho-Substituted P1/P1′ side chains Fulltext Access 13 Pages 2006
Synthesis and cytotoxic activities of β-carboline amino acid ester conjugates Fulltext Access 13 Pages 2006
Arylamine based cathepsin K inhibitors: Investigating P3 heterocyclic substituents Fulltext Access 13 Pages 2006
Synthesis, X-ray crystal structural study, antiviral and cytostatic evaluations of the novel unsaturated acyclic and epoxide nucleoside analogues Fulltext Access 13 Pages 2006
Novel diphenyl ethers: Design, docking studies, synthesis and inhibition of enoyl ACP reductase of Plasmodium falciparum and Escherichia coli Fulltext Access 13 Pages 2006
Synthesis and evaluation of α-hydroxymethylated conjugated nitroalkenes for their anticancer activity: Inhibition of cell proliferation by targeting microtubules Fulltext Access 13 Pages 2006
Synthesis and evaluation of novel 8,5-fused bicyclic peptidomimetic compounds as interleukin-1β converting enzyme (ICE) inhibitors Fulltext Access 13 Pages 2006
Delivery of 2-5A cargo into living cells using the Tat cell penetrating peptide: 2-5A-tat Fulltext Access 13 Pages 2006
Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: Structure–activity relationships of the 4-anilino group Fulltext Access 13 Pages 2006
3D-QSAR analysis of antimalarial farnesyltransferase inhibitors based on a 2,5-diaminobenzophenone scaffold Fulltext Access 13 Pages 2006
Parallel synthesis of 5-cyano-6-aryl-2-thiouracil derivatives as inhibitors for hepatitis C viral NS5B RNA-dependent RNA polymerase Fulltext Access 13 Pages 2006
A semiempirical study of acetylcholine hydrolysis catalyzed by Drosophila melanogaster acetylcholinesterase Fulltext Access 13 Pages 2006
Artificial ribonucleases: From combinatorial libraries to efficient catalysts of RNA cleavage Fulltext Access 13 Pages 2006
Binding mitochondria to cryogel monoliths allows detection of proteins specifically released following permeability transition Fulltext Access 13 Pages 2006
Obtaining high sequence coverage in matrix-assisted laser desorption time-of-flight mass spectrometry for studies of protein modification: Analysis of human serum albumin as a model Fulltext Access 13 Pages 2006
Formation of fluorescent proteins by the attachment of phycoerythrobilin to R-phycoerythrin alpha and beta apo-subunits Fulltext Access 13 Pages 2006
High-throughput affinity ranking of antibodies using surface plasmon resonance microarrays Fulltext Access 13 Pages 2006
Determination of atrazine and its metabolites in mouse urine and plasma by LC–MS analysis Fulltext Access 13 Pages 2006
Magnetic bead-based solid phase for selective extraction of genomic DNA Fulltext Access 13 Pages 2006
Glycosidation of lupane-type triterpenoids as potent in vitro cytotoxic agents Fulltext Access 13 Pages 2006
Sustained augmentation of cardiac α1A-adrenergic drive results in pathological remodeling with contractile dysfunction, progressive fibrosis and reactivation of matricellular protein genes Fulltext Access 13 Pages 2006
A fibrillin-1-fragment containing the elastin-binding-protein GxxPG consensus sequence upregulates matrix metalloproteinase-1: biochemical and computational analysis Fulltext Access 13 Pages 2006
Pd(II)-catalysed and Hg(II)-co-catalysed oxidation of d-glucose and d-fructose by N-bromoacetamide in the presence of perchloric acid: a kinetic and mechanistic study Fulltext Access 13 Pages 2006
Complete assignment of hyaluronan oligosaccharides up to hexasaccharides Fulltext Access 13 Pages 2006
DFT study of α- and β-d-galactopyranose at the B3LYP/6-311++G** level of theory Fulltext Access 13 Pages 2006
Monoglycosyl, diglycosyl, and dinucleoside methylenediphosphonates: direct synthesis and antiviral activity Fulltext Access 13 Pages 2006
Docking studies on glycoside hydrolase Family 47 endoplasmic reticulum α-(1→2)-mannosidase I to elucidate the pathway to the substrate transition state Fulltext Access 13 Pages 2006
Efficient synthesis, structure, and antimicrobial activity of some novel N- and S-β-d-glucosides of 5-pyridin-3-yl-1,2,4-triazoles Fulltext Access 13 Pages 2006
Dynamics of water in supercooled aqueous solutions of glucose and poly(ethylene glycol)s as studied by dielectric spectroscopy Fulltext Access 13 Pages 2006
Enzyme occupancy measurement of intracellular protein tyrosine phosphatase 1B using photoaffinity probes Fulltext Access 13 Pages 2006
Synthesis and biological evaluation of benzopyran analogues bearing class III antiarrhythmic pharmacophores Fulltext Access 13 Pages 2006
MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 6: Exploration of aromatic substituents Fulltext Access 13 Pages 2006
Discovery of diphenyl amine based sodium channel blockers, effective against hNav1.2 Fulltext Access 13 Pages 2006
Quantitative proteome analysis using D-labeled N-ethylmaleimide and 13C-labeled iodoacetanilide by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Fulltext Access 13 Pages 2006
Novel platinum(II) and palladium(II) complexes with cyclin-dependent kinase inhibitors: Synthesis, characterization and antitumour activity Fulltext Access 13 Pages 2006
Synthesis and comparative molecular field analysis (CoMFA) of argentatin B derivatives as growth inhibitors of human cancer cell lines Fulltext Access 13 Pages 2006
Novel vitamin D3 antipsoriatic antedrugs: 16-En-22-oxa-1α,25-(OH)2D3 analogs Fulltext Access 13 Pages 2006
Identification of a buried pocket for potent and selective inhibition of Chk1: Prediction and verification Fulltext Access 13 Pages 2006
Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling Fulltext Access 13 Pages 2006
Synthesis and pharmacology of pyrido[2,3-d]pyrimidinediones bearing polar substituents as adenosine receptor antagonists Fulltext Access 13 Pages 2006
Synthesis and study of the cancer cell growth inhibitory properties of α-, γ-tocopheryl and γ-tocotrienyl 2-phenylselenyl succinates Fulltext Access 13 Pages 2006
Surface-induced changes in protein adsorption and implications for cellular phenotypic responses to surface interaction Fulltext Access 13 Pages 2006
RGD motifs on the surface of baculovirus enhance transduction of human lung carcinoma cells Fulltext Access 13 Pages 2006
Effect of silicon level on rate, quality and progression of bone healing within silicate-substituted porous hydroxyapatite scaffolds Fulltext Access 13 Pages 2006
Poly (d,l-lactic acid) macroporous guidance scaffolds seeded with Schwann cells genetically modified to secrete a bi-functional neurotrophin implanted in the completely transected adult rat thoracic spinal cord Fulltext Access 13 Pages 2006
Temperature-responsive hydroxybutyl chitosan for the culture of mesenchymal stem cells and intervertebral disk cells Fulltext Access 13 Pages 2006
A new in vivo screening model for posterior spinal bone formation: Comparison of ten calcium phosphate ceramic material treatments Fulltext Access 13 Pages 2006
Porous Ti6Al4V scaffold directly fabricating by rapid prototyping: Preparation and in vitro experiment Fulltext Access 13 Pages 2006
Effect of surface-adsorbed proteins and phosphorylation inhibitor AG18 on intracellular protein expression in adherent macrophages Fulltext Access 13 Pages 2006
Biomimetic modification of titanium dental implant model surfaces using the RGDSP-peptide sequence: A cell morphology study Fulltext Access 13 Pages 2006
The use of poly(ethylene glycol) hydrogels to investigate the impact of ECM chemistry and mechanics on smooth muscle cells Fulltext Access 13 Pages 2006
Finalizing the properties of porous scaffolds of aliphatic polyesters through radiation sterilization Fulltext Access 13 Pages 2006
Differential inflammatory macrophage response to rutile and titanium particles Fulltext Access 13 Pages 2006
In vivo behavior of calcium phosphate scaffolds with four different pore sizes Fulltext Access 13 Pages 2006
Cyclic flexure and laminar flow synergistically accelerate mesenchymal stem cell-mediated engineered tissue formation: Implications for engineered heart valve tissues Fulltext Access 13 Pages 2006
Tissue engineering-based cartilage repair with allogenous chondrocytes and gelatin–chondroitin–hyaluronan tri-copolymer scaffold: A porcine model assessed at 18, 24, and 36 weeks Fulltext Access 13 Pages 2006
The uptake of titanium ions by hydroxyapatite particles—structural changes and possible mechanisms Fulltext Access 13 Pages 2006
Chemically surface modified gel (CSMG): An excellent enzyme-immobilization matrix for industrial processes Fulltext Access 13 Pages 2006
Single-step enantioselective amino acid flux analysis by capillary electrophoresis using on-line sample preconcentration with chemical derivatization Fulltext Access 13 Pages 2006
Overproduction of Pichia pastoris or Plasmodium falciparum protein disulfide isomerase affects expression, folding and O-linked glycosylation of a malaria vaccine candidate expressed in P. pastoris Fulltext Access 13 Pages 2006
Identification of StiR, the first regulator of secondary metabolite formation in the myxobacterium Cystobacter fuscus Cb f17.1 Fulltext Access 13 Pages 2006
Effect of lpdA gene knockout on the metabolism in Escherichia coli based on enzyme activities, intracellular metabolite concentrations and metabolic flux analysis by 13C-labeling experiments Fulltext Access 13 Pages 2006
Synthesis of polyhydroxyalkanoates from different short-chain fatty acids by mixed cultures submitted to aerobic dynamic feeding Fulltext Access 13 Pages 2006
Use of adapted Aspergillus niger in the bioleaching of spent refinery processing catalyst Fulltext Access 13 Pages 2006
Adaptations in bacterial catabolic enzyme activity and community structure in membrane-coupled bioreactors fed simple synthetic wastewater Fulltext Access 13 Pages 2006
Protective efficiency of dendrosomes as novel nano-sized adjuvants for DNA vaccination against birch pollen allergy Fulltext Access 13 Pages 2006
Effects of recombinant precursor pathway variations on poly[(R)-3-hydroxybutyrate] synthesis in Saccharomyces cerevisiae Fulltext Access 13 Pages 2006
Phototrophic growth of a Rubisco-deficient mesophilic purple nonsulfur bacterium harboring a Type III Rubisco from a hyperthermophilic archaeon Fulltext Access 13 Pages 2006
Enhancement of pyruvate productivity in Torulopsis glabrata: Increase of NAD+ availability Fulltext Access 13 Pages 2006
Engineering increased thermostability in the thermostable GH-11 xylanase from Thermobacillus xylanilyticus Fulltext Access 13 Pages 2006
Direct capture of plasmid DNA from non-clarified bacterial lysate using polycation-grafted monoliths Fulltext Access 13 Pages 2006
Regulated readthrough: A new method for the alternative tagging and targeting of recombinant proteins Fulltext Access 13 Pages 2006
Recovery of recombinant β-glucosidase by expanded bed adsorption from Pichia pastoris high-cell-density culture broth Fulltext Access 13 Pages 2006
Fractionation of follicle stimulating hormone charge isoforms in their native form by preparative electrophoresis technology Fulltext Access 13 Pages 2006
Under the influence of the active deodorant ingredient 4-hydroxy-3-methoxybenzyl alcohol, the skin bacterium Corynebacterium jeikeium moderately responds with differential gene expression Fulltext Access 13 Pages 2006
Enhancement of l-lysine production in methylotroph Methylophilus methylotrophus by introducing a mutant LysE exporter Fulltext Access 13 Pages 2006
Use of ionic liquids as media for the biocatalytic preparation of flavonoid derivatives with antioxidant potency Fulltext Access 13 Pages 2006
Substrate and inhibitor specificity of class 1 and class 2 histone deacetylases Fulltext Access 13 Pages 2006