A Spectrum of PCSK9 Alleles Contributes to Plasma Levels of Low-Density Lipoprotein Cholesterol Fulltext Access 13 Pages 2006
Isolation and characterization of Schistosoma mansoni constitutive androstane receptor Fulltext Access 13 Pages 2006
Divalent metal requirements for catalysis and stability of the RNA triphosphatase from Trypanosoma cruzi Fulltext Access 13 Pages 2006
Structural analysis of Mycoplasma pneumoniae by cryo-electron tomography Fulltext Access 13 Pages 2006
Electron energy filtering significantly improves amplitude contrast of frozen-hydrated protein at 300 kV Fulltext Access 13 Pages 2006
Study of the localization of iron, ferritin, and hemosiderin in Alzheimer’s disease hippocampus by analytical microscopy at the subcellular level Fulltext Access 13 Pages 2006
Towards high-resolution three-dimensional imaging of native mammalian tissue: Electron tomography of frozen-hydrated rat liver sections Fulltext Access 13 Pages 2006
The transthyretin-related protein: Structural investigation of a novel protein family Fulltext Access 13 Pages 2006
Crystal structure of infectious bursal disease virus VP2 subviral particle at 2.6 Å resolution: Implications in virion assembly and immunogenicity Fulltext Access 13 Pages 2006
Sequence and analysis of the 46.6-kb plasmid pA1 from Sphingomonas sp. A1 that corresponds to the typical IncP-1β plasmid backbone without any accessory gene Fulltext Access 13 Pages 2006
Cigarette Smoking Strongly Modifies the Association of LOC387715 and Age-Related Macular Degeneration Fulltext Access 13 Pages 2006
Mucolipidosis II (I-Cell Disease) and Mucolipidosis IIIA (Classical Pseudo-Hurler Polydystrophy) Are Caused by Mutations in the GlcNAc-Phosphotransferase α/β–Subunits Precursor Gene Fulltext Access 13 Pages 2006
Mutational Spectrum of d-Bifunctional Protein Deficiency and Structure-Based Genotype-Phenotype Analysis Fulltext Access 13 Pages 2006
A Testing Framework for Identifying Susceptibility Genes in the Presence of Epistasis Fulltext Access 13 Pages 2006
Contribution of a Common Single-Nucleotide Polymorphism to the Genetic Predisposition for Erythropoietic Protoporphyria Fulltext Access 13 Pages 2006
A Chromosomal Rearrangement Hotspot Can Be Identified from Population Genetic Variation and Is Coincident with a Hotspot for Allelic Recombination Fulltext Access 13 Pages 2006
Multipoint Linkage Analysis with Many Multiallelic or Dense Diallelic Markers: Markov Chain–Monte Carlo Provides Practical Approaches for Genome Scans on General Pedigrees Fulltext Access 13 Pages 2006
Mutations in TMEM76 * Cause Mucopolysaccharidosis IIIC (Sanfilippo C Syndrome) Fulltext Access 13 Pages 2006
The cytidine deaminases AID and APOBEC-1 exhibit distinct functional properties in a novel yeast selectable system Fulltext Access 13 Pages 2006
Differential transcription profiles in Trypanosoma cruzi associated with clinical forms of Chagas disease: Maxicircle NADH dehydrogenase subunit 7 gene truncation in asymptomatic patient isolates Fulltext Access 13 Pages 2006
The procyclin-associated genes of Trypanosoma brucei are not essential for cyclical transmission by tsetse Fulltext Access 13 Pages 2006
Electron spin relaxation of copper(II) complexes in glassy solution between 10 and 120Â K Fulltext Access 13 Pages 2006
Field-dependent nuclear relaxation of spins 1/2 induced by dipole-dipole couplings to quadrupole spins: LaF3 crystals as an example Fulltext Access 13 Pages 2006
T1Ï MRI contrast in the human brain: Modulation of the longitudinal rotating frame relaxation shutter-speed during an adiabatic RF pulse Fulltext Access 13 Pages 2006
Auxiliary probe design adaptable to existing probes for remote detection NMR, MRI, and time-of-flight tracing Fulltext Access 13 Pages 2006
Fast quantification of proton magnetic resonance spectroscopic imaging with artificial neural networks Fulltext Access 13 Pages 2006
On-line coupling of high temperature GPC and 1H NMR for the analysis of polymers Fulltext Access 13 Pages 2006
Identification of a ubiquitously active promoter of the murine activation-induced cytidine deaminase (AICDA) gene Fulltext Access 13 Pages 2006
Nucleotide-Resolution Mapping of Topoisomerase-Mediated and Apoptotic DNA Strand Scissions at or near an MLL Translocation Hotspot Fulltext Access 13 Pages 2006
Constitutive expression of tumor necrosis factor-alpha in cytotoxic cells of teleosts and its role in regulation of cell-mediated cytotoxicity Fulltext Access 13 Pages 2006
Recombinant CD36 inhibits oxLDL-induced ICAM-1-dependent monocyte adhesion Fulltext Access 13 Pages 2006
Evolutionary conservation of alternative activation of macrophages: Structural and functional characterization of arginase 1 and 2 in carp (Cyprinus carpio L.) Fulltext Access 13 Pages 2006
Characterization and expression sites of newly identified chicken collectins Fulltext Access 13 Pages 2006
Highly phagocytic, CD4hi, CD14hi and CD16hi antigen-presenting cells modulated by tumour-conditioned media retain the capacity to mature and induce TH1 T-cell proliferation Fulltext Access 13 Pages 2006
Biochemical and functional characterization of phosphoserine aminotransferase from Entamoeba histolytica, which possesses both phosphorylated and non-phosphorylated serine metabolic pathways Fulltext Access 13 Pages 2006
Cellular and molecular actions of dinitroaniline and phosphorothioamidate herbicides on Plasmodium falciparum: Tubulin as a specific antimalarial target Fulltext Access 13 Pages 2006
Kinetics and strain variation of phagosome proteins of Entamoeba histolytica by proteomic analysis Fulltext Access 13 Pages 2006
Evolution of non-LTR retrotransposons in the trypanosomatid genomes: Leishmania major has lost the active elements Fulltext Access 13 Pages 2006
Regulation of surface coat exchange by differentiating African trypanosomes Fulltext Access 13 Pages 2006
Anticoccidial kinase inhibitors: Identification of protein kinase targets secondary to cGMP-dependent protein kinase Fulltext Access 13 Pages 2006
Methenyltetrahydrofolate synthetase is a high-affinity catecholamine-binding protein Fulltext Access 13 Pages 2006
The photosynthetic deficiency due to puhC gene deletion in Rhodobacter capsulatus suggests a PuhC protein-dependent process of RC/LH1/PufX complex reorganization Fulltext Access 13 Pages 2006
Cysteine 98 in CYP3A4 contributes to conformational integrity required for P450 interaction with CYP reductase Fulltext Access 13 Pages 2006
Protective role of Cop in Rip2/Caspase-1/Caspase-4-mediated HeLa cell death Fulltext Access 13 Pages 2006
Estrogen receptor alpha regulates matrix metalloproteinase-13 promoter activity primarily through the AP-1 transcriptional regulatory site Fulltext Access 13 Pages 2006
VEGF at the neurovascular interface: Therapeutic implications for motor neuron disease Fulltext Access 13 Pages 2006
Structure, folding, and misfolding of Cu,Zn superoxide dismutase in amyotrophic lateral sclerosis Fulltext Access 13 Pages 2006
Glutaraldehyde and glyoxal cross-linked chitosan microspheres for controlled delivery of centchroman Fulltext Access 13 Pages 2006
Semi-synthetic heparin derivatives: chemical modifications of heparin beyond chain length, sulfate substitution pattern and N-sulfo/N-acetyl groups Fulltext Access 13 Pages 2006
Rosemary (Rosmarinus officinalis) diterpenes affect lipid polymorphism and fluidity in phospholipid membranes Fulltext Access 13 Pages 2006
Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist Fulltext Access 13 Pages 2006
Stochastic entropy QSAR for the in silico discovery of anticancer compounds: Prediction, synthesis, and in vitro assay of new purine carbanucleosides Fulltext Access 13 Pages 2006
Activity-guided isolation of cytotoxic constituents from the bark of Aglaia crassinervia collected in Indonesia Fulltext Access 13 Pages 2006
Ligand design and synthesis of new imidazo[5,1-b]quinazoline derivatives as α1-adrenoceptor agonists and antagonists Fulltext Access 13 Pages 2006
6-Substituted 6H-dibenzo[c,h][2,6]naphthyridin-5-ones: Reversed lactam analogues of ARC-111 with potent topoisomerase I-targeting activity and cytotoxicity Fulltext Access 13 Pages 2006
Synthesis and TNF-α inducing activities of mycoloyl-arabinan motif of mycobacterial cell wall components Fulltext Access 13 Pages 2006
Design, synthesis, and biological activity of N6-substituted-4′-thioadenosines at the human A3 adenosine receptor Fulltext Access 13 Pages 2006
Time-dependent inhibitors of trypanothione reductase: Analogues of the spermidine alkaloid lunarine and related natural products Fulltext Access 13 Pages 2006
Chemotactic peptides: fMLF-OMe analogues incorporating proline–methionine chimeras as N-terminal residue Fulltext Access 13 Pages 2006
An unusual functional group interaction and its potential to reproduce steric and electrostatic features of the transition states of peptidolysis Fulltext Access 13 Pages 2006
Photoaffinity labeling of P450Cam by an imidazole-tethered benzophenone probe Fulltext Access 13 Pages 2006
Regulation of interleukin IL-4, IL-13, IL-10, and their downstream components in lipopolysaccharide-exposed rat lungs. Comparison of the constitutive expression between rats and humans Fulltext Access 13 Pages 2006
Deficient innervation characterizes intestinal strictures in a rat model of colitis Fulltext Access 13 Pages 2006
Mallory body (cytokeratin aggresomes) formation is prevented in vitro by p38 inhibitor Fulltext Access 13 Pages 2006
Pharmacological strategies for the regulation of inducible nitric oxide synthase: Neurodegenerative versus neuroprotective mechanisms Fulltext Access 13 Pages 2006
Apotransferrin decreases the response of oligodendrocyte progenitors to PDGF and inhibits the progression of the cell cycle Fulltext Access 13 Pages 2006
l-deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats Fulltext Access 13 Pages 2006
Blocking of G1/S transition and cell death in the regenerating liver of Hepatitis B virus X protein transgenic mice Fulltext Access 13 Pages 2006
In vivo proteomic analysis of the intracellular bacterial pathogen, Francisella tularensis, isolated from mouse spleen Fulltext Access 13 Pages 2006
5-Alkylated thiazolidinones as follicle-stimulating hormone (FSH) receptor agonists Fulltext Access 13 Pages 2006
Microarray expression profiling and functional characterization of AtTPS genes: Duplicated Arabidopsis thaliana sesquiterpene synthase genes At4g13280 and At4g13300 encode root-specific and wound-inducible (Z)-γ-bisabolene synthases Fulltext Access 13 Pages 2006
Cloning and characterization of a lupeol synthase involved in the synthesis of epicuticular wax crystals on stem and hypocotyl surfaces of Ricinus communis Fulltext Access 13 Pages 2006
Allosteric modulation of the human P-glycoprotein involves conformational changes mimicking catalytic transition intermediates Fulltext Access 13 Pages 2006
Alternatively spliced FGFR-1 isoforms differentially modulate endothelial cell activation of c-YES Fulltext Access 13 Pages 2006
Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: Cloning, tissue distribution, gene structure, and enzymatic activity Fulltext Access 13 Pages 2006
β-Carotene and apocarotenals promote retinoid signaling in BEAS-2B human bronchioepithelial cells Fulltext Access 13 Pages 2006
23-Carboxy-24,25,26,27-tetranorvitamin D3 (calcioic acid) and 24-carboxy-25,26,27-trinorvitamin D3 (cholacalcioic acid): End products of 25-hydroxyvitamin D3 metabolism in rat kidney through C-24 oxidation pathway Fulltext Access 13 Pages 2006
Molecular organization of peroxisomal enzymes: Protein–protein interactions in the membrane and in the matrix Fulltext Access 13 Pages 2006
S-Adenosylmethionine decarboxylase partially regulates cell growth of HL-60 cells by controlling the intracellular ROS level: Early senescence and sensitization to γ-radiation Fulltext Access 13 Pages 2006