Distinct Ubiquitin-Ligase Complexes Define Convergent Pathways for the Degradation of ER Proteins Fulltext Access 13 Pages 2006
CRIg: A Macrophage Complement Receptor Required for Phagocytosis of Circulating Pathogens Fulltext Access 13 Pages 2006
Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin Fulltext Access 13 Pages 2006
C. elegans SIR-2.1 Interacts with 14-3-3 Proteins to Activate DAF-16 and Extend Life Span Fulltext Access 13 Pages 2006
EphB Receptors Coordinate Migration and Proliferation in the Intestinal Stem Cell Niche Fulltext Access 13 Pages 2006
An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor Fulltext Access 13 Pages 2006
Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 Fulltext Access 13 Pages 2006
Blimp1 Defines a Progenitor Population that Governs Cellular Input to the Sebaceous Gland Fulltext Access 13 Pages 2006
Real-Time Observation of RecA Filament Dynamics with Single Monomer Resolution Fulltext Access 13 Pages 2006
FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT Fulltext Access 13 Pages 2006
Ligands for Clathrin-Mediated Endocytosis Are Differentially Sorted into Distinct Populations of Early Endosomes Fulltext Access 13 Pages 2006
Regulation of Body Pigmentation by the Abdominal-B Hox Protein and Its Gain and Loss in Drosophila Evolution Fulltext Access 13 Pages 2006
Comparative Oncogenomics Identifies NEDD9 as a Melanoma Metastasis Gene Fulltext Access 13 Pages 2006
Cotranslocational Degradation Protects the Stressed Endoplasmic Reticulum from Protein Overload Fulltext Access 13 Pages 2006
The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on mRNA Fulltext Access 13 Pages 2006
A C. elegans Model of Nicotine-Dependent Behavior: Regulation by TRP-Family Channels Fulltext Access 13 Pages 2006
A Dynamic Epicardial Injury Response Supports Progenitor Cell Activity during Zebrafish Heart Regeneration Fulltext Access 13 Pages 2006
Distinct Behavioral Responses to Ethanol Are Regulated by Alternate RhoGAP18B Isoforms Fulltext Access 13 Pages 2006
Methods to measure ubiquitin-dependent proteolysis mediated by the anaphase-promoting complex Fulltext Access 13 Pages 2006
Genome-wide Prediction of Mammalian Enhancers Based on Analysis of Transcription-Factor Binding Affinity Fulltext Access 13 Pages 2006
Innate Immunity Gone Awry: Linking Microbial Infections to Chronic Inflammation and Cancer Fulltext Access 13 Pages 2006
A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome Fulltext Access 13 Pages 2006
Ephrin-B2 Controls Cell Motility and Adhesion during Blood-Vessel-Wall Assembly Fulltext Access 13 Pages 2006
Embryonic Dorsal-Ventral Signaling: Secreted Frizzled-Related Proteins as Inhibitors of Tolloid Proteinases Fulltext Access 13 Pages 2006
Identification of a Bacterial Type III Effector Family with G Protein Mimicry Functions Fulltext Access 13 Pages 2006
Virus-Induced Abl and Fyn Kinase Signals Permit Coxsackievirus Entry through Epithelial Tight Junctions Fulltext Access 13 Pages 2006
Structure of DDB1 in Complex with a Paramyxovirus V Protein: Viral Hijack of a Propeller Cluster in Ubiquitin Ligase Fulltext Access 13 Pages 2006
The Crystal Structure of Yeast Protein Disulfide Isomerase Suggests Cooperativity between Its Active Sites Fulltext Access 13 Pages 2006
Presenilin-Dependent ErbB4 Nuclear Signaling Regulates the Timing of Astrogenesis in the Developing Brain Fulltext Access 13 Pages 2006
The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover Fulltext Access 13 Pages 2006
Endoplasmic Reticulum Stress Activates Cleavage of CREBH to Induce a Systemic Inflammatory Response Fulltext Access 13 Pages 2006
A Dynamically Localized Protease Complex and a Polar Specificity Factor Control a Cell Cycle Master Regulator Fulltext Access 13 Pages 2006
Bruno Acts as a Dual Repressor of oskar Translation, Promoting mRNA Oligomerization and Formation of Silencing Particles Fulltext Access 13 Pages 2006
Asymmetric Segregation of the Tumor Suppressor Brat Regulates Self-Renewal in Drosophila Neural Stem Cells Fulltext Access 13 Pages 2006
Crystal Structure of the Ubiquitin Binding Domains of Rabex-5 Reveals Two Modes of Interaction with Ubiquitin Fulltext Access 13 Pages 2006
A Genetic Screen Implicates miRNA-372 and miRNA-373 As Oncogenes in Testicular Germ Cell Tumors Fulltext Access 13 Pages 2006
Cyld Inhibits Tumor Cell Proliferation by Blocking Bcl-3-Dependent NF-κB Signaling Fulltext Access 13 Pages 2006
A Landmark Protein Essential for Establishing and Perpetuating the Polarity of a Bacterial Cell Fulltext Access 13 Pages 2006
Spatiotemporal Regulation of c-Fos by ERK5 and the E3 Ubiquitin Ligase UBR1, and Its Biological Role Fulltext Access 13 Pages 2006
Identification of Early Intermediates of Caspase Activation Using Selective Inhibitors and Activity-Based Probes Fulltext Access 13 Pages 2006
RNAi Screen in Mouse Astrocytes Identifies Phosphatases that Regulate NF-κB Signaling Fulltext Access 13 Pages 2006
Tcf3 Governs Stem Cell Features and Represses Cell Fate Determination in Skin Fulltext Access 13 Pages 2006
Differential Recruitment of the Splicing Machinery during Transcription Predicts Genome-Wide Patterns of mRNA Splicing Fulltext Access 13 Pages 2006
Tip60-Dependent Acetylation of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis Fulltext Access 13 Pages 2006
Initiation and Beyond: Multiple Functions of the Human Mitochondrial Transcription Machinery Fulltext Access 13 Pages 2006
Multiple Mechanisms Control Chromosome Integrity after Replication Fork Uncoupling and Restart at Irreparable UV Lesions Fulltext Access 13 Pages 2006
Cdc7-Dbf4 Phosphorylates MCM Proteins via a Docking Site-Mediated Mechanism to Promote S Phase Progression Fulltext Access 13 Pages 2006
Phosphorylation-Dependent Control of Pc2 SUMO E3 Ligase Activity by Its Substrate Protein HIPK2 Fulltext Access 13 Pages 2006
A Genome-Wide Analysis Indicates that Yeast Pre-mRNA Splicing Is Predominantly Posttranscriptional Fulltext Access 13 Pages 2006
Identification of the TRiC/CCT Substrate Binding Sites Uncovers the Function of Subunit Diversity in Eukaryotic Chaperonins Fulltext Access 13 Pages 2006
Structural and Mechanistic Insights into Ras Association Domains of Phospholipase C Epsilon Fulltext Access 13 Pages 2006
A Short Mitochondrial Form of p19ARF Induces Autophagy and Caspase-Independent Cell Death Fulltext Access 13 Pages 2006
A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA Fulltext Access 13 Pages 2006
S6K1 Regulates GSK3 under Conditions of mTOR-Dependent Feedback Inhibition of Akt Fulltext Access 13 Pages 2006
Binding assays with artificial tethered membranes using surface plasmon resonance Fulltext Access 13 Pages 2006
The zebrafish as a model system for assessing the reinforcing properties of drugs of abuse Fulltext Access 13 Pages 2006
Using peptide arrays to define nuclear carrier binding sites on nucleoporins Fulltext Access 13 Pages 2006
Visualizing single molecules interacting with nuclear pore complexes by narrow-field epifluorescence microscopy Fulltext Access 13 Pages 2006
Cloning of Nt.CviQII nicking endonuclease and its cognate methyltransferase: M.CviQII methylates AG sequences Fulltext Access 13 Pages 2006
SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity Fulltext Access 13 Pages 2006
Deubiquitinating Enzyme Ubp6 Functions Noncatalytically to Delay Proteasomal Degradation Fulltext Access 13 Pages 2006
Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor Fulltext Access 13 Pages 2006
Current strategies for the use of affinity tags and tag removal for the purification of recombinant proteins Fulltext Access 13 Pages 2006
Definition, expression, and characterization of a protein domain in the N-terminus of pregnancy-associated plasma protein-A distantly related to the family of laminin G-like modules Fulltext Access 13 Pages 2006
Physico-chemical and biological characterizations of two human prolactin analogs exhibiting controversial bioactivity, synthesized in Chinese hamster ovary (CHO) cells Fulltext Access 13 Pages 2006
Capturing protein–protein complexes at equilibrium: The holdup comparative chromatographic retention assay Fulltext Access 13 Pages 2006
Nuclear Retention of the Tumor Suppressor cPML by the Homeodomain Protein TGIF Restricts TGF-β Signaling Fulltext Access 13 Pages 2006
Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: Structures and mechanisms of product formation Fulltext Access 13 Pages 2006
Role for CED-9 and Egl-1 as Regulators of Mitochondrial Fission and Fusion Dynamics Fulltext Access 13 Pages 2006
A Family of Diverse Cul4-Ddb1-Interacting Proteins Includes Cdt2, which Is Required for S Phase Destruction of the Replication Factor Cdt1 Fulltext Access 13 Pages 2006
Activation of IKK by TNFα Requires Site-Specific Ubiquitination of RIP1 and Polyubiquitin Binding by NEMO Fulltext Access 13 Pages 2006
Chromosomal Association of the Smc5/6 Complex Reveals that It Functions in Differently Regulated Pathways Fulltext Access 13 Pages 2006
Nuclear Pore Components Are Involved in the Transcriptional Regulation of Dosage Compensation in Drosophila Fulltext Access 13 Pages 2006
Structural and Functional Analysis of E6 Oncoprotein: Insights in the Molecular Pathways of Human Papillomavirus-Mediated Pathogenesis Fulltext Access 14 Pages 2006
Destruction or Potentiation of Different Prions Catalyzed by Similar Hsp104 Remodeling Activities Fulltext Access 14 Pages 2006
Molecular Basis for G Protein Control of the Prokaryotic ATP Sulfurylase Fulltext Access 14 Pages 2006
ING Tumor Suppressor Proteins Are Critical Regulators of Chromatin Acetylation Required for Genome Expression and Perpetuation Fulltext Access 14 Pages 2006
Lipidomic strategies to study structural and functional defects of ABC-transporters in cellular lipid trafficking Fulltext Access 14 Pages 2006
Constraining G1-Specific Transcription to Late G1 Phase: The MBF-Associated Corepressor Nrm1 Acts via Negative Feedback Fulltext Access 14 Pages 2006