GALC transduction leads to morphological improvement of the twitcher oligodendrocytes in vivo Fulltext Access 12 Pages 2005
Use of fish liver PLHC-1 cells and zebrafish embryos in cytotoxicity assays Fulltext Access 12 Pages 2005
Integrating gene and protein expression data: pattern analysis and profile mining Fulltext Access 12 Pages 2005
Intracellular galactose-1-phosphate accumulation leads to environmental stress response in yeast model Fulltext Access 12 Pages 2005
Structure-activity relationships for inhibition of human cholinesterases by alkyl amide phenothiazine derivatives Fulltext Access 12 Pages 2005
Natural and synthetic cage compounds incorporating the 2,9,10-trioxatricyclo[4.3.1.03,8]decane type moiety Fulltext Access 12 Pages 2005
Non-stochastic and stochastic linear indices of the 'molecular pseudograph's atom adjacency matrix': application to 'in silico' studies for the rational discovery of new antimalarial compounds Fulltext Access 12 Pages 2005
Synthesis and biological evaluation of nucleobase-modified analogs of the anticancer compounds 3â²-C-ethynyluridine (EUrd) and 3â²-C-ethynylcytidine (ECyd) Fulltext Access 12 Pages 2005
Modified mannose disaccharides as substrates and inhibitors of a polyprenol monophosphomannose-dependent α-(1â6)-mannosyltransferase involved in mycobacterial lipoarabinomannan biosynthesis Fulltext Access 12 Pages 2005
Recombinant PAS-heme domains of oxygen sensing proteins: High level production and physical characterization Fulltext Access 12 Pages 2005
Preparation of (25R)- and (25S)-26-functionalized steroids as tools for biosynthetic studies of cholic acids Fulltext Access 12 Pages 2005
Analytical strategies for the direct mass spectrometric analysis of steroid and corticosteroid phase II metabolites Fulltext Access 12 Pages 2005
In vitro aromatic bioactivation of the weak estrogen E2α and genesis of DNA adducts Fulltext Access 12 Pages 2005
Growth-plate chondrocytes respond to 17β-estradiol with sex-specific increases in IP3 and intracellular calcium ion signalling via a capacitative entry mechanism Fulltext Access 12 Pages 2005
Three-dimensional co-culture models to study prostate cancer growth, progression, and metastasis to bone Fulltext Access 12 Pages 2005
Fusion oncogenes and tumor type specificity-insights from salivary gland tumors Fulltext Access 12 Pages 2005
A custom-designed recombinant multiepitope protein as a dengue diagnostic reagent Fulltext Access 12 Pages 2005
General synthesis and biological evaluation of α-1-C-substituted derivatives of fagomine (2-deoxynojirimycin-α-C-glycosides) Fulltext Access 12 Pages 2005
The screening of expression and purification conditions for replicative DNA polymerase associated B-subunits, assignment of the exonuclease activity to the C-terminus of archaeal pol D DP1 subunit Fulltext Access 12 Pages 2005
Generation of a vector system facilitating cloning of DMBT1 variants and recombinant expression of functional full-length DMBT1 Fulltext Access 12 Pages 2005
Yersinia pestis outer membrane type III secretion protein YscC: expression, purification, characterization, and induction of specific antiserum Fulltext Access 12 Pages 2005
A direct nitric oxide gas delivery system for bacterial and mammalian cell cultures Fulltext Access 12 Pages 2005
Inducible nitric oxide synthase expression is inhibited by myeloperoxidase Fulltext Access 12 Pages 2005
Studying the S-nitrosylation of model peptides and eNOS protein by mass spectrometry Fulltext Access 12 Pages 2005
Residual cholesterol synthesis and simvastatin induction of cholesterol synthesis in Smith-Lemli-Opitz syndrome fibroblasts Fulltext Access 12 Pages 2005
Structure-based discovery of human l-xylulose reductase inhibitors from database screening and molecular docking Fulltext Access 12 Pages 2005
The binding of novel two-color fluorescence probe FA to serum albumins of different species Fulltext Access 12 Pages 2005
Vitamin D receptor (VDR) ablation alters carcinogen-induced tumorigenesis in mammary gland, epidermis and lymphoid tissues Fulltext Access 12 Pages 2005
Structural and active site analysis of plasmepsins of Plasmodium falciparum: Potential anti-malarial targets Fulltext Access 12 Pages 2005
The adrenocortical tumor cell line NCI-H295R as an in vitro screening system for the evaluation of CYP11B2 (aldosterone synthase) and CYP11B1 (steroid-11β-hydroxylase) inhibitors Fulltext Access 12 Pages 2005
Upregulation of human mitochondrial NADH dehydrogenase subunit 5 in intestinal epithelial cells is modulated by Vibrio cholerae pathogenesis Fulltext Access 12 Pages 2005
Synthesis of free and sulphoconjugated 16-androstene steroids by the Leydig cells of the mature domestic boar Fulltext Access 12 Pages 2005
Transcriptional repression of fibroblast growth factor 8 by transforming growth factor-β in androgen-dependent SC-3 cells Fulltext Access 12 Pages 2005
Gene regulation by the glucocorticoid receptor: Structure:function relationship Fulltext Access 12 Pages 2005
A novel method of estimation of lipophilicity using distance-based topological indices: dominating role of equalized electronegativity Fulltext Access 12 Pages 2005
Functional characterization and purification of a Saccharomyces cerevisiae ADP/ATP carrier-iso 1 cytochrome c fusion protein Fulltext Access 12 Pages 2005
Protocols for production of selenomethionine-labeled proteins in 2-L polyethylene terephthalate bottles using auto-induction medium Fulltext Access 12 Pages 2005
Mutations and promoter SNPs in RUNX2, a transcriptional regulator of bone formation Fulltext Access 12 Pages 2005
Expression and characterization of a low molecular weight recombinant human gelatin: development of a substitute for animal-derived gelatin with superior features Fulltext Access 12 Pages 2005
Mitochondrial energy metabolism is markedly impaired by d-2-hydroxyglutaric acid in rat tissues Fulltext Access 12 Pages 2005
Prenatal diagnosis for methylmalonic acidemia and inborn errors of vitamin B12 metabolism and transport Fulltext Access 12 Pages 2005
Synthesis and anti-viral activity of a series of d- and l-2â²-deoxy-2â²-fluororibonucleosides in the subgenomic HCV replicon system Fulltext Access 12 Pages 2005
Design, synthesis, and evaluation of potent and selective benzoyleneurea-based inhibitors of protein geranylgeranyltransferase-I Fulltext Access 12 Pages 2005
Light induction of the carotenoid biosynthesis pathway in Blakeslea trispora Fulltext Access 13 Pages 2005
Inducible nitric oxide synthase (iNOS) in tumor biology: The two sides of the same coin Fulltext Access 13 Pages 2005
Microenvironmental control of premalignant disease: the role of intercellular adhesion in the progression of squamous cell carcinoma Fulltext Access 13 Pages 2005
Stromagenesis: The changing face of fibroblastic microenvironments during tumor progression Fulltext Access 13 Pages 2005
Expression of agsA, one of five 1,3-α-d-glucan synthase-encoding genes in Aspergillus niger, is induced in response to cell wall stress Fulltext Access 13 Pages 2005
The tetraspanin gene ClPLS1 is essential for appressorium-mediated penetration of the fungal pathogen Colletotrichum lindemuthianum Fulltext Access 13 Pages 2005
Characterisation and biosynthesis of d-erythroascorbic acid in Phycomyces blakesleeanus Fulltext Access 13 Pages 2005
Discovery, biosynthesis, and structure elucidation of new metabolites of norandrostenedione using in vitro systems Fulltext Access 13 Pages 2005
Characterisation of the mating-type locus in the genus Xanthoria (lichen-forming ascomycetes, Lecanoromycetes) Fulltext Access 13 Pages 2005
Microsporidian polar tube proteins: Highly divergent but closely linked genes encode PTP1 and PTP2 in members of the evolutionarily distant Antonospora and Encephalitozoon groups Fulltext Access 13 Pages 2005
Molecular cloning of developmentally specific genes by representational difference analysis during the fruiting body formation in the basidiomycete Lentinula edodes Fulltext Access 13 Pages 2005
Aflatoxin conducive and non-conducive growth conditions reveal new gene associations with aflatoxin production Fulltext Access 13 Pages 2005
Candida albicans CHT3 encodes the functional homolog of the Cts1 chitinase of Saccharomyces cerevisiae Fulltext Access 13 Pages 2005
Contrasting phenotypes in three patients with novel mutations in mitochondrial tRNA genes Fulltext Access 13 Pages 2005
The steroid-binding subunit of the Na/K-ATPase as a progesterone receptor on the amphibian oocyte plasma membrane Fulltext Access 13 Pages 2005
Niemann-Pick C disease: Use of denaturing high performance liquid chromatography for the detection of NPC1 and NPC2 genetic variations and impact on management of patients and families Fulltext Access 13 Pages 2005
True and false discovery in DNA microarray experiments: Transcriptome changes in the hippocampus of presenilin 1 mutant mice Fulltext Access 13 Pages 2005
Effect of nomegestrol acetate on estrogen biosynthesis and transformation in MCF-7 and T47-D breast cancer cells Fulltext Access 13 Pages 2005
Cytotoxic effects induced by oxidative stress in cultured mammalian cells and protection provided by Hsp27 expression Fulltext Access 13 Pages 2005
Rush hour at the promoter: How the ubiquitin-proteasome pathway polices the traffic flow of nuclear receptor-dependent transcription Fulltext Access 13 Pages 2005
Anti-cancer activities of novel D-ring modified 2-substituted estrogen-3-O-sulfamates Fulltext Access 13 Pages 2005
Role of the proteasome in the regulation of estrogen receptor α turnover and function in MCF-7 breast carcinoma cells Fulltext Access 13 Pages 2005
Comparative study of oestrogenic properties of eight phytoestrogens in MCF7 human breast cancer cells Fulltext Access 13 Pages 2005
Translation modulation of acid β-glucosidase in HepG2 cells: participation of the PKC pathway Fulltext Access 13 Pages 2005
Placental defects are associated with male lethality in bare patches and striated embryos deficient in the NAD(P)H Steroid Dehydrogenase-like (NSDHL) Enzyme Fulltext Access 13 Pages 2005
Partial nicotinic receptor blockade unmasks a modulatory role of nitric oxide on urethral striated neuromuscular transmission Fulltext Access 13 Pages 2005
Requirements for reliable determination of binding affinity constants by kinetic approach Fulltext Access 13 Pages 2005
Production, purification, and characterization of human scFv antibodies expressed in Saccharomyces cerevisiae, Pichia pastoris, and Escherichia coli Fulltext Access 13 Pages 2005
5α-Reductase activity in Lycopersicon esculentum: Cloning and functional characterization of LeDET2 and evidence of the presence of two isoenzymes Fulltext Access 13 Pages 2005
Functional expression of bitistatin, a disintegrin with potential use in molecular imaging of thromboembolic disease Fulltext Access 13 Pages 2005
Improved yields for baculovirus-mediated expression of human His6-PDK1 and His6-PKBβ/Akt2 and characterization of phospho-specific isoforms for design of inhibitors that stabilize inactive conformations Fulltext Access 13 Pages 2005
Regulation of osteoblastic phenotype and gene expression by hop-derived phytoestrogens Fulltext Access 13 Pages 2005
Refolding, purification, and crystallization of apical membrane antigen 1 from Plasmodium falciparum Fulltext Access 13 Pages 2005