Nanoscale variation in surface charge of synthetic hydroxyapatite detected by chemically and spatially specific high-resolution force spectroscopy Fulltext Access 13 Pages 2005
The nature of target-unrelated peptides recovered in the screening of phage-displayed random peptide libraries with antibodies Fulltext Access 13 Pages 2005
Complex glycosaminoglycans: profiling substitution patterns by two-dimensional nuclear magnetic resonance spectroscopy Fulltext Access 13 Pages 2005
Analysis of connective tissues by laser capture microdissection and reverse transcriptase-polymerase chain reaction Fulltext Access 13 Pages 2005
Detection of small differences in actomyosin function using actin labeled with different phalloidin conjugates Fulltext Access 13 Pages 2005
The optimization of quantitative reverse transcription PCR for verification of cDNA microarray data Fulltext Access 13 Pages 2005
A surface plasmon resonance-based assay for small molecule inhibitors of human cyclophilin A Fulltext Access 13 Pages 2005
Determination of saccharide content in pneumococcal polysaccharides and conjugate vaccines by GC-MSD Fulltext Access 13 Pages 2005
Theoretical aspects of 13C metabolic flux analysis with sole quantification of carbon dioxide labeling Fulltext Access 13 Pages 2005
Genome-based identification of diagnostic molecular markers for human lung carcinomas by PLS-DA Fulltext Access 13 Pages 2005
The independent role of cyclic flexure in the early in vitro development of an engineered heart valve tissue Fulltext Access 13 Pages 2005
Probing the role of tightly bound phosphoenolpyruvate in Escherichia coli 3-deoxy-d-manno-octulosonate 8-phosphate synthase catalysis using quantitative time-resolved electrospray ionization mass spectrometry in the millisecond time range Fulltext Access 13 Pages 2005
Bacterial cellulose as a potential scaffold for tissue engineering of cartilage Fulltext Access 13 Pages 2005
Crosslinked hyaluronic acid hydrogels: a strategy to functionalize and pattern Fulltext Access 13 Pages 2005
Quantitative immunoassay of biotoxins on hydrogel-based protein microchips Fulltext Access 13 Pages 2005
A high-throughput fluorescence-anisotropy screen that identifies small molecule inhibitors of the DNA binding of B-ZIP transcription factors Fulltext Access 13 Pages 2005
On-line multi-analyzer monitoring of biomass, glucose and acetate for growth rate control of a Vibrio cholerae fed-batch cultivation Fulltext Access 13 Pages 2005
Enzymatic grafting of chitosan onto Bombyx mori silk fibroin: kinetic and IR vibrational studies Fulltext Access 13 Pages 2005
Enhanced production of cellobiohydrolases in Trichoderma reesei and evaluation of the new preparations in biofinishing of cotton Fulltext Access 13 Pages 2005
Diffusive and convective transport through hollow fiber membranes for liver cell culture Fulltext Access 13 Pages 2005
Dynamic optimization of bioprocesses: Efficient and robust numerical strategies Fulltext Access 13 Pages 2005
Influence of induction and operation mode on recombinant rhamnulose 1-phosphate aldolase production by Escherichia coli using the T5 promoter Fulltext Access 13 Pages 2005
Baculovirus-mediated production of HDV-like particles in BHK cells using a novel oscillating bioreactor Fulltext Access 13 Pages 2005
Structure-immunomodulating activity relationships of a pectic arabinogalactan from Vernonia kotschyana Sch. Bip. ex Walp. Fulltext Access 13 Pages 2005
Synthesis of deoxy and acylamino derivatives of lactose and use of these for probing the active site of Neisseria meningitidis N-acetylglucosaminyltransferase Fulltext Access 13 Pages 2005
Conformational features of cepacian: the exopolysaccharide produced by clinical strains of Burkholderia cepacia Fulltext Access 13 Pages 2005
Hyaluronan conformations on surfaces: effect of surface charge and hydrophobicity Fulltext Access 13 Pages 2005
Syntheses of TN building blocks Nα-(9-fluorenylmethoxycarbonyl)-O-(3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-d-galactopyranosyl)-l-serine/l-threonine pentafluorophenyl esters: comparison of protocols and elucidation of side reactions Fulltext Access 13 Pages 2005
Synthesis and receptor assay of aromatic-ethynyl-aromatic derivatives with potent mGluR5 antagonist activity Fulltext Access 13 Pages 2005
Exploring the active site of phenylethanolamine N-methyltransferase: 3-alkyl-7-substituted-1,2,3,4-tetrahydroisoquinoline inhibitors Fulltext Access 13 Pages 2005
Part 3: Synthesis and biological evaluation of some analogs of the antitumor agents, 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid, and 2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid Fulltext Access 13 Pages 2005
Studies of non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: Synthesis and structure-activity relationships of 2-cyano and 2-hydroxy thiazolidenebenzenesulfonamide derivatives Fulltext Access 13 Pages 2005
Synthesis, structure-activity relationship, and p210bcr-abl protein tyrosine kinase activity of novel AG 957 analogs Fulltext Access 13 Pages 2005
Synthesis and biological evaluation of lipophilic Ca1a2L analogues as potential bisubstrate inhibitors of protein:geranylgeranyl transferase-1 Fulltext Access 13 Pages 2005
Morphological studies of oligodeoxyribonucleotides probes covalently immobilized at polystyrene modified surfaces Fulltext Access 13 Pages 2005
Synthesis and biological activity of sulphostin analogues, novel dipeptidyl peptidase IV inhibitors Fulltext Access 13 Pages 2005
Asymmetric transesterification of secondary alcohols catalyzed by feruloyl esterase from Humicola insolens Fulltext Access 13 Pages 2005
Bisubstrate analog probes for the insulin receptor protein tyrosine kinase: Molecular yardsticks for analyzing catalytic mechanism and inhibitor design Fulltext Access 13 Pages 2005
Oxidative cascades: A facile biosynthetic strategy for the assembly of complex molecules Fulltext Access 13 Pages 2005
Yellow pigments used in rapid identification of aflatoxin-producing Aspergillus strains are anthraquinones associated with the aflatoxin biosynthetic pathway Fulltext Access 13 Pages 2005
A transcriptional regulatory element screening system reveals a novel E2F1/pRb transcription regulation pathway Fulltext Access 13 Pages 2005
Analysis of slow-binding enzyme inhibitors at elevated enzyme concentrations Fulltext Access 13 Pages 2005
Achiral-chiral LC/LC-MS/MS coupling for determination of chiral discrimination effects in phenprocoumon metabolism Fulltext Access 13 Pages 2005
Fabrication of DNA microarrays onto poly(methyl methacrylate) with ultraviolet patterning and microfluidics for the detection of low-abundant point mutations Fulltext Access 13 Pages 2005
Calculating the probability of detection for inhibitors in enzymatic or binding reactions in high-throughput screening Fulltext Access 13 Pages 2005
Repair of articular cartilage defects treated by microfracture and a three-dimensional collagen matrix Fulltext Access 13 Pages 2005
Design and synthesis of complementing ligands for mutant thyroid hormone receptor TRβ(R320H): a tailor-made approach toward the treatment of resistance to thyroid hormone Fulltext Access 13 Pages 2005
4-Alkyliden-β-lactams conjugated to polyphenols: Synthesis and inhibitory activity Fulltext Access 13 Pages 2005
Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic α,β-unsaturated esters Fulltext Access 13 Pages 2005
DFT-based ranking of zinc-binding groups in histone deacetylase inhibitors Fulltext Access 13 Pages 2005
Core-modified porphyrins. Part 5: Electronic effects on photophysical and biological properties in vitro Fulltext Access 13 Pages 2005
The synthesis and evaluation of 10- and 12-membered ring benzofused enediyne amino acids Fulltext Access 13 Pages 2005
Indolyl esters and amides related to indomethacin are selective COX-2 inhibitors Fulltext Access 13 Pages 2005
Esters and amides of 2,3-dimethoxy-8,9-methylenedioxy-benzo[i]phenanthridine-12-carboxylic acid: Potent cytotoxic and topoisomerase I-targeting agents Fulltext Access 13 Pages 2005
Nitroarylmethylcarbamate prodrugs of doxorubicin for use with nitroreductase gene-directed enzyme prodrug therapy Fulltext Access 13 Pages 2005
A-ring hydroxymethyl 19-nor analogs of the natural hormone 1α,25-dihydroxyvitamin D3: synthesis and preliminary biological evaluation Fulltext Access 13 Pages 2005
New 3- and 4-hydroxyfuranones as anti-oxidants and anti-inflammatory agents Fulltext Access 13 Pages 2005
Quantitative analysis of macrophage apoptosis vs. necrosis induced by cobalt and chromium ions in vitro Fulltext Access 13 Pages 2005
Antimycobacterial activity of new 3-substituted 5-(pyridin-4-yl)-3H-1,3,4-oxadiazol-2-one and 2-thione derivatives. Preliminary molecular modeling investigations Fulltext Access 13 Pages 2005
In vitro cartilage tissue engineering with 3D porous aqueous-derived silk scaffolds and mesenchymal stem cells Fulltext Access 13 Pages 2005
Implantation of preadipocyte-loaded hyaluronic acid-based scaffolds into nude mice to evaluate potential for soft tissue engineering Fulltext Access 13 Pages 2005
Tissue engineering of human cartilage and osteochondral composites using recirculation bioreactors Fulltext Access 13 Pages 2005
Aspects of in vitro fatigue in human cortical bone: time and cycle dependent crack growth Fulltext Access 13 Pages 2005
In vitro characterization of vascular endothelial growth factor and dexamethasone releasing hydrogels for implantable probe coatings Fulltext Access 13 Pages 2005
In vitro and in vivo evaluation of differentially demineralized cancellous bone scaffolds combined with human bone marrow stromal cells for tissue engineering Fulltext Access 13 Pages 2005
Gene expression clustering using self-organizing maps: analysis of the macrophage response to particulate biomaterials Fulltext Access 13 Pages 2005
Chitosan/β-lactoglobulin core–shell nanoparticles as nutraceutical carriers Fulltext Access 13 Pages 2005
Size-controlled hydroxyapatite nanoparticles as self-organized organic–inorganic composite materials Fulltext Access 13 Pages 2005
Oxathiolene oxide synthesis via chelation-controlled addition of organometallic reagents to alkynols followed by addition of sulfur electrophiles and evaluation of oxathiolene oxides as anticarcinogenic enzyme inducers Fulltext Access 13 Pages 2005
Capture of bacterial endotoxins using a supermacroporous monolithic matrix with immobilized polyethyleneimine, lysozyme or polymyxin B Fulltext Access 13 Pages 2005
Oral administration of a cholera toxin B subunit-insulin fusion protein produced in silkworm protects against autoimmune diabetes Fulltext Access 13 Pages 2005
Integration of mechanical cell disruption and fluidised bed recovery of G3PDH from unclarified disrupted yeast: A comparative study of the performance of unshielded and polymer shielded dye-ligand chromatography systems Fulltext Access 13 Pages 2005
A platform for high-throughput expression of recombinant human enzymes secreted by insect cells Fulltext Access 13 Pages 2005
Heterologous production of five Hepatitis C virus-derived antigens in three Saccharomyces cerevisiae host strains Fulltext Access 13 Pages 2005
Libraries of synthetic stationary-phase and stress promoters as a tool for fine-tuning of expression of recombinant proteins in Escherichia coli Fulltext Access 13 Pages 2005
Cell-free xenogenic vascular grafts fixed with glutaraldehyde or genipin: In vitro and in vivo studies Fulltext Access 13 Pages 2005
Conformational folding of xyloglucan side chains in aqueous solution from molecular dynamics simulation Fulltext Access 13 Pages 2005
Thermoelectroelastic solutions for surface bone remodeling under axial and transverse loads Fulltext Access 13 Pages 2005
5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family Fulltext Access 13 Pages 2005
Protein linear indices of the ‘macromolecular pseudograph α-carbon atom adjacency matrix’ in bioinformatics. Part 1: Prediction of protein stability effects of a complete set of alanine substitutions in Arc repressor Fulltext Access 13 Pages 2005
Systematic synthesis of galloyl-substituted procyanidin B1 and B2, and their ability of DPPH radical scavenging activity and inhibitory activity of DNA polymerases Fulltext Access 13 Pages 2005
Design, synthesis and evaluation of 2,4-diaminoquinazolines as inhibitors of trypanosomal and leishmanial dihydrofolate reductase Fulltext Access 13 Pages 2005
QSAR study for a novel series of ortho monosubstituted phenoxy analogues of α1-adrenoceptor antagonist WB4101 Fulltext Access 13 Pages 2005
Design, synthesis and anti-plasmodial evaluation in vitro of new 4-aminoquinoline isatin derivatives Fulltext Access 13 Pages 2005
Indolizine 1-sulfonates as potent inhibitors of 15-lipoxygenase from soybeans Fulltext Access 13 Pages 2005
Connecting traditional QSAR and molecular simulations of papain hydrolysis—importance of charge transfer Fulltext Access 13 Pages 2005
Design and synthesis of subtype-selective cyclooxygenase (COX) inhibitors derived from thalidomide Fulltext Access 13 Pages 2005
Protonated structures of naturally occurring deoxyribonucleic acids and their interaction with berberine Fulltext Access 13 Pages 2005
Stereochemical determination and bioactivity assessment of (S)-(+)-curcuphenol dimers isolated from the marine sponge Didiscus aceratus and synthesized through laccase biocatalysis Fulltext Access 13 Pages 2005