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Daneshyari Molecular Medicine Journas Latest Articles

Molecular Medicine Research Articles

Preparation and biological evaluation of cyclopentadienyl-based 99mTc-complexes [(Cp-R)99mTc(CO)3] mimicking benzamides for malignant melanoma targeting
Fulltext Access 10 Pages 2010
IGF-1, oxidative stress and atheroprotection
Fulltext Access 10 Pages 2010
The pathophysiology, diagnosis and prognosis of adrenocortical tumors revisited by transcriptome analyses
Fulltext Access 10 Pages 2010
FlipADAM: a potential new SPECT imaging agent for the serotonin transporter
Fulltext Access 10 Pages 2010
Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer
Fulltext Access 10 Pages 2010
Synthesis, radiofluorination and first evaluation of [18F]fluorophenylsulfonyl- and [18F]fluorophenylsulfinyl-piperidines as serotonin 5-HT2A receptor antagonists for PET
Fulltext Access 10 Pages 2010
Radiosynthesis and evaluation of [11C]YM-202074 as a PET ligand for imaging the metabotropic glutamate receptor type 1
Fulltext Access 10 Pages 2010
Interactions of the circadian CLOCK system and the HPA axis
Fulltext Access 10 Pages 2010
Insulin signaling meets mitochondria in metabolism
Fulltext Access 10 Pages 2010
Copper-64-diacetyl-bis (N4-methylthiosemicarbazone) accumulates in rich regions of CD133+ highly tumorigenic cells in mouse colon carcinoma
Fulltext Access 10 Pages 2010
Preclinical evaluation of an 18F-labelled β1-adrenoceptor selective radioligand based on ICI 89,406
Fulltext Access 10 Pages 2010
Sex hormone metabolism in lung development and maturation
Fulltext Access 10 Pages 2010
Synthesis of novel 68Ga-labeled amino acid derivatives for positron emission tomography of cancer cells
Fulltext Access 10 Pages 2010
Vitamin D: newly discovered actions require reconsideration of physiologic requirements
Fulltext Access 10 Pages 2010
Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity
Fulltext Access 10 Pages 2010
High-resolution imaging of brain 5-HT1B receptors in the rhesus monkey using [11C]P943
Fulltext Access 10 Pages 2010
SIRT1 Deacetylase in POMC Neurons Is Required for Homeostatic Defenses against Diet-Induced Obesity
Fulltext Access 10 Pages 2010
The feasibility of using a baculovirus vector to deliver the sodium-iodide symporter gene as a reporter
Fulltext Access 10 Pages 2010
Combination therapy in A549 cells
Fulltext Access 10 Pages 2010
Intestinal Ferritin H Is Required for an Accurate Control of Iron Absorption
Fulltext Access 10 Pages 2010
Autoradiography study and SPECT imaging of reporter gene HSV1-tk expression in heart
Fulltext Access 10 Pages 2010
Therapeutic efficacy and microSPECT/CT imaging of 188Re-DXR-liposome in a C26 murine colon carcinoma solid tumor model
Fulltext Access 10 Pages 2010
Insulin Controls the Spatial Distribution of GLUT4 on the Cell Surface through Regulation of Its Postfusion Dispersal
Fulltext Access 10 Pages 2010
miR-378∗ Mediates Metabolic Shift in Breast Cancer Cells via the PGC-1β/ERRγ Transcriptional Pathway
Fulltext Access 10 Pages 2010
Resistance to High-Fat Diet-Induced Obesity and Insulin Resistance in Mice with Very Long-Chain Acyl-CoA Dehydrogenase Deficiency
Fulltext Access 10 Pages 2010
Expression of folate transporters in human placenta and implications for homocysteine metabolism
Fulltext Access 10 Pages 2010
Stretch and inflammation-induced Pre-B cell colony-enhancing factor (PBEF/Visfatin) and Interleukin-8 in amniotic epithelial cells
Fulltext Access 10 Pages 2010
Fatty acids alter glycerolipid metabolism and induce lipid droplet formation, syncytialisation and cytokine production in human trophoblasts with minimal glucose effect or interaction
Fulltext Access 10 Pages 2010
Mesenchymal stem cells in human placental chorionic villi reside in a vascular Niche
Fulltext Access 10 Pages 2010
Enhanced proapoptotic gene expression of XAF1, CASP8 and TNFSF10 in the bovine endometrium during early pregnancy is not correlated with augmented apoptosis
Fulltext Access 10 Pages 2010
Current TopicCellular and Molecular Regulation of Spiral Artery Remodelling: Lessons from the Cardiovascular Field
Fulltext Access 10 Pages 2010
Increased SOD1 association with chromatin, DNA damage, p53 activation, and apoptosis in a cellular model of SOD1-linked ALS
Fulltext Access 10 Pages 2010
Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes
Fulltext Access 10 Pages 2010
A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia
Fulltext Access 10 Pages 2010
Mitochondria in Huntington's disease
Fulltext Access 10 Pages 2010
Activation of fibroblasts in cancer stroma
Fulltext Access 10 Pages 2010
Retention of prolyl hydroxylase PHD2 in the cytoplasm prevents PHD2-induced anchorage-independent carcinoma cell growth
Fulltext Access 10 Pages 2010
D4S234E, a novel p53-responsive gene, induces apoptosis in response to DNA damage
Fulltext Access 10 Pages 2010
Liprin-α4 is a new hypoxia-inducible target gene required for maintenance of cell–cell contacts
Fulltext Access 10 Pages 2010
Down-regulation of UDP-glucose dehydrogenase affects glycosaminoglycans synthesis and motility in HCT-8 colorectal carcinoma cells
Fulltext Access 10 Pages 2010
Lumican inhibits cell migration through α2β1 integrin
Fulltext Access 10 Pages 2010
Micropatterned matrix directs differentiation of human mesenchymal stem cells towards myocardial lineage
Fulltext Access 10 Pages 2010
Upregulation of the GRIM-19 gene suppresses invasion and metastasis of human gastric cancer SGC-7901 cell line
Fulltext Access 10 Pages 2010
TRAM1 is involved in disposal of ER membrane degradation substrates
Fulltext Access 10 Pages 2010
Compound C sensitizes Caki renal cancer cells to TRAIL-induced apoptosis through reactive oxygen species-mediated down-regulation of c-FLIPL and Mcl-1
Fulltext Access 10 Pages 2010
Distinct Patterns of Gene-Specific Methylation in Mammalian Placentas: Implications for Placental Evolution and Function
Fulltext Access 10 Pages 2010
Vav1 and PU.1 are recruited to the CD11b promoter in APL-derived promyelocytes: Role of Vav1 in modulating PU.1-containing complexes during ATRA-induced differentiation
Fulltext Access 10 Pages 2010
Regulation of MYPT1 stability by the E3 ubiquitin ligase SIAH2
Fulltext Access 10 Pages 2010
Expression of thyroid hormone transporters in the human placenta and changes associated with intrauterine growth restriction
Fulltext Access 10 Pages 2010
Nemo-like kinase (NLK) expression in osteoblastic cells and suppression of osteoblastic differentiation
Fulltext Access 10 Pages 2010
Erythropoietin suppresses epithelial to mesenchymal transition and intercepts Smad signal transduction through a MEK-dependent mechanism in pig kidney (LLC-PK1) cell lines
Fulltext Access 10 Pages 2010
Current TopicEndothelial Progenitor Cells: Their Potential in the Placental Vasculature and Related Complications
Fulltext Access 10 Pages 2010
Anti-EGFRvIII monoclonal antibody armed with 177Lu: in vivo comparison of macrocyclic and acyclic ligands
Fulltext Access 10 Pages 2010
Characterisation of Hofbauer Cells in First and Second Trimester Placenta: Incidence, Phenotype, Survival in vitro and Motility
Fulltext Access 10 Pages 2010
Evaluation of anti-podoplanin rat monoclonal antibody NZ-1 for targeting malignant gliomas
Fulltext Access 10 Pages 2010
An electro-amalgamation approach to isolate no-carrier-added 177Lu from neutron irradiated Yb for biomedical applications
Fulltext Access 10 Pages 2010
B-1 cell participation in T-cell-mediated alloimmune response
Fulltext Access 11 Pages 2010
Induction of IP-10/CXCL10 secretion as an immunomodulatory effect of low-dose adjuvant interferon-alpha during treatment of melanoma
Fulltext Access 11 Pages 2010
Transferred T cells preferentially adhere in the BALT of CD26-deficient recipient lungs during asthma
Fulltext Access 11 Pages 2010
Mesenchymal stem cell-conditioned medium accelerates skin wound healing: An in vitro study of fibroblast and keratinocyte scratch assays
Fulltext Access 11 Pages 2010
α-Actinin 1 and α-actinin 4: Contrasting roles in the survival, motility, and RhoA signaling of astrocytoma cells
Fulltext Access 11 Pages 2010
Long-term culture and differentiation of CNS precursors derived from anterior human neural rosettes following exposure to ventralizing factors
Fulltext Access 11 Pages 2010
High glucose concentrations attenuate hypoxia-inducible factor-1α expression and signaling in non-tumor cells
Fulltext Access 11 Pages 2010
Identification of a fibronectin interaction site in the extracellular matrix protein ameloblastin
Fulltext Access 11 Pages 2010
Chemistry around imidazopyrazine and ibuprofen: Discovery of novel fatty acid amide hydrolase (FAAH) inhibitors
Fulltext Access 11 Pages 2010
Neutrophil granulocytes promote the migratory activity of MDA-MB-468 human breast carcinoma cells via ICAM-1
Fulltext Access 11 Pages 2010
PET imaging of fatty acid amide hydrolase in the brain: synthesis and biological evaluation of an 11C-labelled URB597 analogue
Fulltext Access 11 Pages 2010
Imaging of I2-imidazoline receptors by small-animal PET using 2-(3-fluoro-[4-11C]tolyl)-4,5-dihydro-1H-imidazole ([11C]FTIMD)
Fulltext Access 11 Pages 2010
Validation of two fluoro-analogues of N,N-dimethyl-2-(2′-amino-4′-hydroxymethyl-phenylthio)benzylamine as serotonin transporter imaging agents using microPET
Fulltext Access 11 Pages 2010
Pre-clinical evaluation of a 3-nitro-1,2,4-triazole analogue of [18F]FMISO as hypoxia-selective tracer for PET
Fulltext Access 11 Pages 2010
In vitro structure–activity relationship of Re-cyclized octreotide analogues
Fulltext Access 11 Pages 2010
111In- or 99mTc-labeled recombinant VEGF bioconjugates: in vitro evaluation of their cytotoxicity on porcine aortic endothelial cells overexpressing Flt-1 receptors
Fulltext Access 11 Pages 2010
Optimization, biological evaluation and microPET imaging of copper-64-labeled bombesin agonists, [64Cu-NO2A-(X)-BBN(7–14)NH2], in a prostate tumor xenografted mouse model
Fulltext Access 11 Pages 2010
Hair follicle-specific keratins and their diseases
Fulltext Access 11 Pages 2010
Technetium-99m-labeled Arg-Gly-Asp-conjugated alpha-melanocyte stimulating hormone hybrid peptides for human melanoma imaging
Fulltext Access 11 Pages 2010
Up-regulation of calcium-dependent proteolysis in human myoblasts under acute oxidative stress
Fulltext Access 11 Pages 2010
The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway
Fulltext Access 11 Pages 2010
Osteopontin induces β-catenin signaling through activation of Akt in prostate cancer cells
Fulltext Access 11 Pages 2010
Thymus cell antigen 1 (Thy1, CD90) is expressed by lymphatic vessels and mediates cell adhesion to lymphatic endothelium
Fulltext Access 11 Pages 2010
Enlarged lateral ventricles and aberrant behavior in mice overexpressing PDGF-B in embryonic neural stem cells
Fulltext Access 11 Pages 2010
Photodynamic effects of isosteric water-soluble phthalocyanines on human nasopharynx KB carcinoma cells
Fulltext Access 11 Pages 2010
QSAR study of carboxylic acid derivatives as HIV-1 Integrase inhibitors
Fulltext Access 11 Pages 2010
Novel 99mTc ‘4 + 1’ peptide conjugates: Tuning the biodistribution by variation of coligands
Fulltext Access 11 Pages 2010
Cytokine treatment of macrophage suppression of T cell activation
Fulltext Access 11 Pages 2010
Specific inhibition of the classical complement pathway with an engineered single-chain Fv to C1q globular heads decreases complement activation by apoptotic cells
Fulltext Access 11 Pages 2010
Galectin-3 plays a modulatory role in the life span and activation of murine neutrophils during early Toxoplasma gondii infection
Fulltext Access 11 Pages 2010
Cannabinoids and experimental models of multiple sclerosis
Fulltext Access 11 Pages 2010
Importance of CCL2-CCR2A/2B signaling for monocyte migration into spheroids of breast cancer-derived fibroblasts
Fulltext Access 11 Pages 2010
Dissecting TLR3 signalling in dendritic cells
Fulltext Access 11 Pages 2010
Neuromediators in inflammation—a macrophage/nerve connection
Fulltext Access 11 Pages 2010
MBL-associated serine protease-3 circulates in high serum concentrations predominantly in complex with Ficolin-3 and regulates Ficolin-3 mediated complement activation
Fulltext Access 11 Pages 2010
Butyrate in vitro immune-modulatory effects might be mediated through a proliferation-related induction of apoptosis
Fulltext Access 11 Pages 2010
Alternating 2′-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist
Fulltext Access 11 Pages 2010
Paths reunited: Initiation of the classical and lectin pathways of complement activation
Fulltext Access 11 Pages 2010
TNFRSF6B neutralization antibody inhibits proliferation and induces apoptosis in hepatocellular carcinoma cell
Fulltext Access 11 Pages 2010
Importance of DNA damage checkpoints in the pathogenesis of human cancers
Fulltext Access 11 Pages 2010
Effects of ketoconazole on the biodistribution and metabolism of [11C]loperamide and [11C]N-desmethyl-loperamide in wild-type and P-gp knockout mice
Fulltext Access 11 Pages 2010
In vivo binding of [68Ga]-DOTATOC to somatostatin receptors in neuroendocrine tumours — impact of peptide mass
Fulltext Access 11 Pages 2010
Treatment of transplanted tumor of lung adenocarcinoma A549 transfected by human somatostatin receptor subtype 2 (hsstr2) gene with 188Re-RC-160
Fulltext Access 11 Pages 2010
In vitro and in vivo evaluation of [99mTc]-labeled tricarbonyl His-annexin A5 as an imaging agent for the detection of phosphatidylserine-expressing cells
Fulltext Access 11 Pages 2010
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