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Daneshyari Molecular Medicine Journas Latest Articles

Molecular Medicine Research Articles

Synthesis and biological evaluation of 4,5-diphenyloxazolone derivatives on route towards selective COX-2 inhibitors
Fulltext Access 8 Pages 2009
Molecular structure and stability of perindopril erbumine and perindopril l-arginine complexes
Fulltext Access 8 Pages 2009
Synthesis and anti-inflammatory activity of newer quinazolin-4-one derivatives
Fulltext Access 8 Pages 2009
Preparation and in vitro evaluation of benzylsulfanyl benzoxazole derivatives as potential antituberculosis agents
Fulltext Access 8 Pages 2009
Antiamoebic coumarins from the root bark of Adina cordifolia and their new thiosemicarbazone derivatives
Fulltext Access 8 Pages 2009
Examination of growth inhibitory properties of synthetic chalcones for which antibacterial activity was predicted
Fulltext Access 8 Pages 2009
New insights into the antioxidant activity of hydroxycinnamic acids: Synthesis and physicochemical characterization of novel halogenated derivatives
Fulltext Access 8 Pages 2009
Synthesis and DNA-binding studies of two ruthenium(II) complexes of an intercalating ligand
Fulltext Access 8 Pages 2009
Mucoadjuvant properties of lipo- and glycoconjugated derivatives of oligochitosans
Fulltext Access 8 Pages 2009
Design and synthesis of new N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides as anti-inflammatory agents
Fulltext Access 8 Pages 2009
Design, synthesis, and biological evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14α-demethylase
Fulltext Access 8 Pages 2009
Gallium(III) complexes of 2-pyridineformamide thiosemicarbazones: Cytotoxic activity against malignant glioblastoma
Fulltext Access 8 Pages 2009
Novel 2-aryl-naphtho[1,2-d]oxazole derivatives as potential PTP-1B inhibitors showing antihyperglycemic activities
Fulltext Access 8 Pages 2009
RETRACTED: 2-Azetidinone derivatives: Design, synthesis, in vitro anti-microbial, cytotoxic activities and DNA cleavage study
Fulltext Access 8 Pages 2009
Spectrophotometric and HPLC determinations of anti-diabetic drugs, rosiglitazone maleate and metformin hydrochloride, in pure form and in pharmaceutical preparations
Fulltext Access 8 Pages 2009
Dialkylamino and nitrogen heterocyclic analogues of hexadecylphosphocholine and cetyltrimetylammonium bromide: Effect of phosphate group and environment of the ammonium cation on their biological activity
Fulltext Access 8 Pages 2009
Synthesis of 6-aminomethyl derivatives of benzopyran-4-one with dual biological properties: Anti-inflammatory-analgesic and antimicrobial
Fulltext Access 8 Pages 2009
Discovery of potential ZAP-70 kinase inhibitors: Pharmacophore design, database screening and docking studies
Fulltext Access 8 Pages 2009
Microwave assisted synthesis of unsaturated jasmone heterocyclic analogues as new fragrant substances
Fulltext Access 8 Pages 2009
Structure–activity relationships for dipeptide prodrugs of acyclovir: Implications for prodrug design
Fulltext Access 8 Pages 2009
Synthesis and preliminary screening of novel indole-3-methanamines as 5-HT4 receptor ligands
Fulltext Access 8 Pages 2009
To determine the cytotoxicity of chlorambucil and one of its nitro-derivatives, conjugated to prasterone and pregnenolone, towards eight human cancer cell-lines
Fulltext Access 8 Pages 2009
Synthesis and evaluation of antibacterial activities of andrographolide analogues
Fulltext Access 8 Pages 2009
Calcium and ATP handling in human NADH:Ubiquinone oxidoreductase deficiency
Fulltext Access 8 Pages 2009
Role of nitric oxide in obsessive-compulsive behavior and its involvement in the anti-compulsive effect of paroxetine in mice
Fulltext Access 8 Pages 2009
Nitrite reduction and superoxide-dependent nitric oxide degradation by Arabidopsis mitochondria: Influence of external NAD(P)H dehydrogenases and alternative oxidase in the control of nitric oxide levels
Fulltext Access 8 Pages 2009
The Drosophila Hindgut Lacks Constitutively Active Adult Stem Cells but Proliferates in Response to Tissue Damage
Fulltext Access 8 Pages 2009
DNA Methyltransferase 1 Is Essential for and Uniquely Regulates Hematopoietic Stem and Progenitor Cells
Fulltext Access 8 Pages 2009
Generation of Induced Pluripotent Stem Cells from Human Cord Blood
Fulltext Access 8 Pages 2009
The resistance of electron-transport chain Fe–S clusters to oxidative damage during the reaction of peroxynitrite with mitochondrial complex II and rat-heart pericardium
Fulltext Access 8 Pages 2009
Neuronal nitric oxide synthase: Structure, subcellular localization, regulation, and clinical implications
Fulltext Access 8 Pages 2009
Comparison of nitric oxide-induced oxidation of recombinant oxyhemoglobin subunits using a competition experiment
Fulltext Access 8 Pages 2009
The effect of nitric oxide on vaccinia virus-encoded ribonucleotide reductase
Fulltext Access 8 Pages 2009
Cardiac nitric oxide synthase-1 localization within the cardiomyocyte is accompanied by the adaptor protein, CAPON
Fulltext Access 8 Pages 2009
Prominent role of NF-κB in the induction of endothelial activation by endogenous nitric oxide inhibition
Fulltext Access 8 Pages 2009
Synthesis and antitumor activity of some new xanthotoxin derivatives
Fulltext Access 8 Pages 2009
Mitochondrial proteome evolution and genetic disease
Fulltext Access 8 Pages 2009
Synthesis and affinity to DNA of phenylbenzoimidazoles and benzoimidazo[1,2-c]quinazolines
Fulltext Access 8 Pages 2009
Synthesis and anti-HSV-1 evaluation of some pyrazoles and fused pyrazolopyrimidines
Fulltext Access 8 Pages 2009
Synthesis and in vivo antidiabetic activity of novel dispiropyrrolidines through [3 + 2] cycloaddition reactions with thiazolidinedione and rhodanine derivatives
Fulltext Access 8 Pages 2009
Mechanism of unusual formation of 3-(5-phenyl-3H-[1,2,4]dithiazol-3-yl)chromen-4-ones and 4-oxo-4H-chromene-3-carbothioic acid N-phenylamides and their antimicrobial evaluation
Fulltext Access 8 Pages 2009
Synthesis and antimicrobial properties of polymerizable quaternary ammoniums
Fulltext Access 8 Pages 2009
Evaluation of in vivo wound-healing potential of 2-[4-(2,4-dimethoxy-benzoyl)-phenoxy]-1-[4-(3-piperidin-4-yl-propyl)-piperidin-1-yl]-ethanone derivatives
Fulltext Access 8 Pages 2009
Design, synthesis and biological evaluation of novel nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents
Fulltext Access 8 Pages 2009
Promising carboranylquinazolines for boron neutron capture therapy: Synthesis, characterization, and in vitro toxicity evaluation
Fulltext Access 8 Pages 2009
Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds
Fulltext Access 8 Pages 2009
Non-imidazole histamine H3 ligands, Part IV: SAR of 1-[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propylpiperazine derivatives
Fulltext Access 8 Pages 2009
QSAR analysis of salicylamide isosteres with the use of quantum chemical molecular descriptors
Fulltext Access 8 Pages 2009
The metabolism of CYP2C9 and CYP2C19 for gliclazide by homology modeling and docking study
Fulltext Access 8 Pages 2009
Novel 8-deaza-5,6,7,8-tetrahydroaminopterin derivatives as dihydrofolate inhibitor: Design, synthesis and antifolate activity
Fulltext Access 8 Pages 2009
Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities
Fulltext Access 8 Pages 2009
Oligonucleotide–polyamine conjugates: Influence of length and position of 2′-attached polyamines on duplex stability and antisense effect
Fulltext Access 8 Pages 2009
Synthesis of some N-substituted nitroimidazole derivatives as potential antioxidant and antifungal agents
Fulltext Access 8 Pages 2009
Synthesis and in vitro cytotoxic evaluation of novel 3,4,5-trimethoxyphenyl substituted β-carboline derivatives
Fulltext Access 8 Pages 2009
Synthesis and biological evaluation of a new family of anti-benzylanilinosulfonamides as CA IX inhibitors
Fulltext Access 8 Pages 2009
Synthesis and antibacterial evaluation of novel 4-alkyl substituted phenyl β-aldehyde ketone derivatives
Fulltext Access 8 Pages 2009
Synthesis and pharmacological evaluation of 2-substituted benzo[b]thiophenes as anti-inflammatory and analgesic agents
Fulltext Access 8 Pages 2009
Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity, Part 1
Fulltext Access 8 Pages 2009
Preparation and antimicrobial behaviour of quaternary ammonium thiol derivatives able to be grafted on metal surfaces
Fulltext Access 8 Pages 2009
Hydroxychalcones induce apoptosis in B16-F10 melanoma cells via GSH and ATP depletion
Fulltext Access 8 Pages 2009
Enhanced activity of fluorinated quaternary ammonium surfactants against Pseudomonas aeruginosa
Fulltext Access 8 Pages 2009
Synthesis, structure and biological activity of copper(II) complexes of 4-(2-pyridylmethyl)-1,7-dimethyl-1,4,7-triazonane-2,6-dione and 4-(2-pyridylethyl)-1,7-dimethyl-1,4,7-triazonane-2,6-dione
Fulltext Access 8 Pages 2009
Photodynamic inactivation of Candida albicans sensitized by tri- and tetra-cationic porphyrin derivatives
Fulltext Access 8 Pages 2009
Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine
Fulltext Access 8 Pages 2009
Quantitative structure–activity relationship study of serotonin (5-HT7) receptor inhibitors using modified ant colony algorithm and adaptive neuro-fuzzy interference system (ANFIS)
Fulltext Access 8 Pages 2009
Circular dichroism studies of type III collagen mimetic peptides with anti- or pro-aggregant activities on human platelets
Fulltext Access 8 Pages 2009
QSPR modeling bioconcentration factor (BCF) by balance of correlations
Fulltext Access 8 Pages 2009
Development of CoMFA and CoMSIA models of cytotoxicity data of anti-HIV-1-phenylamino-1H-imidazole derivatives
Fulltext Access 8 Pages 2009
An investigation into the role of surfactants in controlling particle size of polymeric nanocapsules containing penicillin-G in double emulsion
Fulltext Access 8 Pages 2009
Design, synthesis and antimycobacterial activity of some novel imidazo[1,2-c]pyrimidines
Fulltext Access 8 Pages 2009
3D-QSAR studies on the inhibitors of AP-1 and NF-κB mediated transcriptional activation
Fulltext Access 8 Pages 2009
DNA-targeting pyrroloquinoline-linked butenone and chalcones: Synthesis and biological evaluation
Fulltext Access 8 Pages 2009
Synthesis, characterisation and in vitro cytotoxicity studies of a series of chiral platinum(II) complexes based on the 2-aminomethylpyrrolidine ligand: X-ray crystal structure of [PtCl2(R-dimepyrr)] (R-dimepyrr = N-dimethyl-2(R)-aminomethylpyrrolidine)
Fulltext Access 8 Pages 2009
Synthesis and antiviral activity of new pyrazole and thiazole derivatives
Fulltext Access 8 Pages 2009
Synthesis and immunosuppressive activity of cyclolinopeptide A analogues containing homophenylalanine
Fulltext Access 8 Pages 2009
Synthesis and anticonvulsant activity of some new bishydrazones derived from 3,4-dipropyloxythiophene
Fulltext Access 8 Pages 2009
Convenient synthesis and antimicrobial evaluation of some novel 2-substituted-3-methylbenzofuran derivatives
Fulltext Access 8 Pages 2009
Synthesis, spectral characterization, in-vitro microbiological evaluation and cytotoxic activities of novel macrocyclic bis hydrazone
Fulltext Access 8 Pages 2009
An in vitro characterization study of new near infrared dyes for molecular imaging
Fulltext Access 8 Pages 2009
Important pharmacophoric features of pan PPAR agonists: Common chemical feature analysis and virtual screening
Fulltext Access 8 Pages 2009
Synthesis of novel pyrazole derivatives and evaluation of their antidepressant and anticonvulsant activities
Fulltext Access 8 Pages 2009
Synthesis, spectroscopic characterization, X-ray structure and evaluation of binding parameters of new triorganotin(IV) dithiocarboxylates with DNA
Fulltext Access 8 Pages 2009
A novel QSAR model for predicting the inhibition of CXCR3 receptor by 4-N-aryl-[1,4] diazepane ureas
Fulltext Access 8 Pages 2009
Synthesis and antitumoral activity of novel thiazolobenzotriazole, thiazoloindolo[3,2-c]quinoline and quinolinoquinoline derivatives
Fulltext Access 8 Pages 2009
Perspectives in designing anti aggregation agents as Alzheimer disease drugs
Fulltext Access 8 Pages 2009
Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrugs of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease
Fulltext Access 8 Pages 2009
Design, synthesis and hypolipidemic activity of novel 2-(naphthalen-2-yloxy)propionic acid derivatives as desmethyl fibrate analogs
Fulltext Access 8 Pages 2009
2D- and 3D-QSAR studies on 54 anti-tumor Rubiaceae-type cyclopeptides
Fulltext Access 8 Pages 2009
QSAR study of Akt/protein kinase B (PKB) inhibitors using support vector machine
Fulltext Access 8 Pages 2009
Quantitative structure activity relationship (QSAR) of piperine analogsfor bacterial NorA efflux pump inhibitors
Fulltext Access 8 Pages 2009
Contact-active microbicidal gold surfaces using immobilization of quaternary ammonium thiol derivatives
Fulltext Access 8 Pages 2009
Synthesis and biochemical evaluation of a cyclic RGD oxorhenium complex as new ligand of αVβ3 integrin
Fulltext Access 8 Pages 2009
OXPHOS gene expression and control in mitochondrial disorders
Fulltext Access 9 Pages 2009
Functional analysis of the posttranslational modifications of the death receptor 6
Fulltext Access 9 Pages 2009
Efficient repair of protein radicals by ascorbate
Fulltext Access 9 Pages 2009
Mitochondrial superoxide plays a crucial role in the development of mitochondrial dysfunction during high glucose exposure in rat renal proximal tubular cells
Fulltext Access 9 Pages 2009
Skin cells and tissue are capable of using l-ergothioneine as an integral component of their antioxidant defense system
Fulltext Access 9 Pages 2009
The use of ebselen for radioprotection in cultured cells and mice
Fulltext Access 9 Pages 2009
Reversible and irreversible modifications of skeletal muscle proteins in a rat model of acute oxidative stress
Fulltext Access 9 Pages 2009
A critical approach to the therapy of mitochondrial respiratory chain and oxidative phosphorylation diseases
Fulltext Access 9 Pages 2009
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