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Daneshyari Molecular Medicine Journas Latest Articles

Molecular Medicine Research Articles

Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor
Fulltext Access 13 Pages 2006
The glycoprotein hGC-1 binds to cadherin and lectins
Fulltext Access 13 Pages 2006
Reconstitution of recycling from the phagosomal compartment in streptolysin O-permeabilized macrophages: Role of Rab11
Fulltext Access 13 Pages 2006
Zasp/Cypher internal ZM-motif containing fragments are sufficient to co-localize with α-actinin—Analysis of patient mutations
Fulltext Access 13 Pages 2006
In situ SUMOylation analysis reveals a modulatory role of RanBP2 in the nuclear rim and PML bodies
Fulltext Access 13 Pages 2006
Dissociation of the complex between CD151 and laminin-binding integrins permits migration of epithelial cells
Fulltext Access 13 Pages 2006
TGF-β1-induced PAI-1 expression is E box/USF-dependent and requires EGFR signaling
Fulltext Access 13 Pages 2006
Rin1 regulates insulin receptor signal transduction pathways
Fulltext Access 13 Pages 2006
Involvement of Golgi-associated Lyn tyrosine kinase in the translocation of annexin II to the endoplasmic reticulum under oxidative stress
Fulltext Access 13 Pages 2006
Phenotypic characterization of telomerase-immortalized primary non-malignant and malignant tumor-derived human prostate epithelial cell lines
Fulltext Access 13 Pages 2006
Endothelial nitric oxide synthase is segregated from caveolin-1 and localizes to the leading edge of migrating cells
Fulltext Access 13 Pages 2006
Evidence for a differential functional regulation of the two β3-integrins αVβ3 and αIIbβ3
Fulltext Access 13 Pages 2006
Characterization of a novel Dp71 dystrophin-associated protein complex (DAPC) present in the nucleus of HeLa cells: Members of the nuclear DAPC associate with the nuclear matrix
Fulltext Access 13 Pages 2006
Structure of daunomycin complexed to d-TGATCA by two-dimensional nuclear magnetic resonance spectroscopy
Fulltext Access 13 Pages 2006
Identification and characterization of GSRP-56, a novel Golgi-localized spectrin repeat-containing protein
Fulltext Access 13 Pages 2006
Galectin-8 binds specific β1 integrins and induces polarized spreading highlighted by asymmetric lamellipodia in Jurkat T cells
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Role of lipids and actin in the formation of clathrin-coated pits
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Laminopathy-inducing lamin A mutants can induce redistribution of lamin binding proteins into nuclear aggregates
Fulltext Access 13 Pages 2006
ZNF198, a zinc finger protein rearranged in myeloproliferative disease, localizes to the PML nuclear bodies and interacts with SUMO-1 and PML
Fulltext Access 13 Pages 2006
PTH-related protein upregulates integrin α6β4 expression and activates Akt in breast cancer cells
Fulltext Access 13 Pages 2006
Cortactin affects cell migration by regulating intercellular adhesion and cell spreading
Fulltext Access 13 Pages 2006
The tight junction protein ZO-2 has several functional nuclear export signals
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p120 serine and threonine phosphorylation is controlled by multiple ligand–receptor pathways but not cadherin ligation
Fulltext Access 13 Pages 2006
Effect of the anti-receptor ligand-blocking 225 monoclonal antibody on EGF receptor endocytosis and sorting
Fulltext Access 13 Pages 2006
Hypoxia protects HepG2 cells against etoposide-induced apoptosis VIA a HIF-1-independent pathway
Fulltext Access 13 Pages 2006
Endothelial cell responses towards low-fouling surfaces bearing RGD in a three-dimensional environment
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Synthesis and antiproliferative activities of diversely substituted glycosyl-isoindigo derivatives
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Synthesis and biological evaluation of modified acridines: the effect of N- and O- substituent in the nitrogenated ring on antitumor activity
Fulltext Access 13 Pages 2006
Design of β-carboline derivatives as DNA-targeting antitumor agents
Fulltext Access 13 Pages 2006
Arylmethyl substituted derivatives of Fosmidomycin: Synthesis and antimalarial activity
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Recognition of pathogens and activation of immune responses in Drosophila and horseshoe crab innate immunity
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Differences in CXCR4-mediated signaling in B cells
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The PCNA-associated factor KIAA0101/p15PAF binds the potential tumor suppressor product p33ING1b
Fulltext Access 13 Pages 2006
Characterization of a serine protease-mediated cell death program activated in human leukemia cells
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Neuronal differentiation of human mesenchymal stem cells: Changes in the expression of the Alzheimer's disease-related gene seladin-1
Fulltext Access 13 Pages 2006
Carboxypeptidase cathepsin X mediates β2-integrin-dependent adhesion of differentiated U-937 cells
Fulltext Access 13 Pages 2006
Okadaic acid overcomes the blocked cell cycle caused by depleting Cdc2-related kinases in Trypanosoma brucei
Fulltext Access 13 Pages 2006
Molecular basis for the redox control of nuclear transport of the structural chromatin protein Hmgb1
Fulltext Access 13 Pages 2006
Molecular interactions with obscurin are involved in the localization of muscle-specific small ankyrin1 isoforms to subcompartments of the sarcoplasmic reticulum
Fulltext Access 13 Pages 2006
Macroscopic and Microscopic Aspects of Collared Peccary and White-lipped Peccary Placenta
Fulltext Access 14 Pages 2006
Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis
Fulltext Access 14 Pages 2006
Analyses of pancreas development by generation of gfp transgenic zebrafish using an exocrine pancreas-specific elastaseA gene promoter
Fulltext Access 14 Pages 2006
Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing
Fulltext Access 14 Pages 2006
Actomyosin tension is required for correct recruitment of adherens junction components and zonula occludens formation
Fulltext Access 14 Pages 2006
Neutrophil elastase sorting involves plasma membrane trafficking requiring the C-terminal propeptide
Fulltext Access 14 Pages 2006
Antiangiogenesis in cancer therapy—endostatin and its mechanisms of action
Fulltext Access 14 Pages 2006
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
Fulltext Access 14 Pages 2006
Peroxisome division is impaired in a CHO cell mutant with an inactivating point-mutation in dynamin-like protein 1 gene
Fulltext Access 14 Pages 2006
IL4/PGE2 induction of an enlarged early endosomal compartment in mouse macrophages is Rab5-dependent
Fulltext Access 14 Pages 2006
A Bpag1 isoform involved in cytoskeletal organization surrounding the nucleus
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Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1α in Huntington's disease neurodegeneration
Fulltext Access 14 Pages 2006
The inhibitory effects of endostatin on endothelial cells are modulated by extracellular matrix
Fulltext Access 14 Pages 2006
Diverse Calcium Channel Types are Present in the Human Placental Syncytiotrophoblast Basal Membrane
Fulltext Access 14 Pages 2006
S100A8 and S100A9 activate MAP kinase and NF-κB signaling pathways and trigger translocation of RAGE in human prostate cancer cells
Fulltext Access 14 Pages 2006
Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling
Fulltext Access 14 Pages 2006
Rabbit embryonic stem cell lines derived from fertilized, parthenogenetic or somatic cell nuclear transfer embryos
Fulltext Access 14 Pages 2006
The effect of genetic diversity on angiogenesis
Fulltext Access 14 Pages 2006
Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP
Fulltext Access 14 Pages 2006
Dynamics of the actin-binding protein drebrin in motile cells and definition of a juxtanuclear drebrin-enriched zone
Fulltext Access 14 Pages 2006
The Drosophila orthologue of xPlkk1 is not essential for Polo activation and is necessary for proper contractile ring formation
Fulltext Access 14 Pages 2006
Myostatin regulation of muscle development: Molecular basis, natural mutations, physiopathological aspects
Fulltext Access 14 Pages 2006
The arginine methyltransferase PRMT2 binds RB and regulates E2F function
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Involvement of H- and N-Ras isoforms in transforming growth factor-β1-induced proliferation and in collagen and fibronectin synthesis
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Human progenitor cells isolated from the developing cortex undergo decreased neurogenesis and eventual senescence following expansion in vitro
Fulltext Access 14 Pages 2006
The ins and outs of peroxisomes: Co-ordination of membrane transport and peroxisomal metabolism
Fulltext Access 14 Pages 2006
Biosynthesis of heme in mammals
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Molecular aspects of Cu, Fe and Zn homeostasis in plants
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Rottlerin inhibits stimulated enzymatic secretion and several intracellular signaling transduction pathways in pancreatic acinar cells by a non-PKC-δ-dependent mechanism
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CRM 1-mediated degradation and agonist-induced down-regulation of β-adrenergic receptor mRNAs
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Recognition of the tumor suppressor protein p53 and other protein targets by the calcium-binding protein S100B
Fulltext Access 14 Pages 2006
Emerging perspectives in store-operated Ca2+ entry: Roles of Orai, Stim and TRP
Fulltext Access 14 Pages 2006
Peroxisomal disorders: The single peroxisomal enzyme deficiencies
Fulltext Access 14 Pages 2006
The ER-peroxisome connection in plants: Development of the “ER semi-autonomous peroxisome maturation and replication” model for plant peroxisome biogenesis
Fulltext Access 14 Pages 2006
Copper trafficking to the mitochondrion and assembly of copper metalloenzymes
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Peroxisomes and bile acid biosynthesis
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Peroxisomal β-oxidation—A metabolic pathway with multiple functions
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Reactive nitrogen species induce nuclear factor-κB-mediated protein degradation in skeletal muscle cells
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Oxidation of Macromolecules: DNA, Lipid, Protein, Carbohydrate
Fulltext Access 14 Pages 2006
Signal Transduction and Gene Expression
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Antioxidants, Nutrition & Health
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A novel SOD-mimetic permeability transition inhibitor agent protects ischemic heart by inhibiting both apoptotic and necrotic cell death
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Characterizing pathogenic processes in Batten disease: Use of small eukaryotic model systems
Fulltext Access 14 Pages 2006
Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility
Fulltext Access 14 Pages 2006
Endogenous spartin, mutated in hereditary spastic paraplegia, has a complex subcellular localization suggesting diverse roles in neurons
Fulltext Access 14 Pages 2006
Dissecting the sequence specific functions of alternative N-terminal isoforms of mouse bullous pemphigoid antigen 1
Fulltext Access 14 Pages 2006
Rho kinase regulates phagocytosis, surface expression of GlcNAc, and Golgi fragmentation of apoptotic PC12 cells
Fulltext Access 14 Pages 2006
The murine TRAIL receptor signals caspase-independent cell death through ceramide
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Unraveling androgen receptor interactomes by an array-based method: Discovery of proto-oncoprotein c-Rel as a negative regulator of androgen receptor
Fulltext Access 14 Pages 2006
Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages
Fulltext Access 14 Pages 2006
P-selectin activates integrin-mediated colon carcinoma cell adhesion to fibronectin
Fulltext Access 14 Pages 2006
Analysis of the influence of subcellular localization of the HIV Rev protein on Rev-dependent gene expression by multi-fluorescence live-cell imaging
Fulltext Access 14 Pages 2006
Integrin-dependent neuroblastoma cell adhesion and migration on laminin is regulated by expression levels of two enzymes in the O-mannosyl-linked glycosylation pathway, PomGnT1 and GnT-Vb
Fulltext Access 14 Pages 2006
Coxsackievirus and adenovirus receptor (CAR) is expressed in male germ cells and forms a complex with the differentiation factor JAM-C in mouse testis
Fulltext Access 14 Pages 2006
Nuclear localisation of endogenous SUMO-1-modified PDGF-C in human thyroid tissue and cell lines
Fulltext Access 14 Pages 2006
SNEV overexpression extends the life span of human endothelial cells
Fulltext Access 14 Pages 2006
MEK-ERK signaling plays diverse roles in the regulation of facial chondrogenesis
Fulltext Access 14 Pages 2006
78 kDa receptor for Man6P-independent lysosomal enzyme targeting: Biosynthetic transport from endoplasmic reticulum to “high-density vesicles”
Fulltext Access 14 Pages 2006
Co-localization of cortactin and phosphotyrosine identifies active invadopodia in human breast cancer cells
Fulltext Access 14 Pages 2006
NOV/CCN3 impairs muscle cell commitment and differentiation
Fulltext Access 14 Pages 2006
Cell surface 5T4 antigen is transiently upregulated during early human embryonic stem cell differentiation: Effect of 5T4 phenotype on neural lineage formation
Fulltext Access 14 Pages 2006
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