PcrA Helicase Dismantles RecA Filaments by Reeling in DNA in Uniform Steps Fulltext Access 12 Pages 2010
A Region of the Human HOXD Cluster that Confers Polycomb-Group Responsiveness Fulltext Access 12 Pages 2010
Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content Fulltext Access 12 Pages 2010
The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments Fulltext Access 12 Pages 2010
H2A.Z-Containing Nucleosomes Mediate the Thermosensory Response in Arabidopsis Fulltext Access 12 Pages 2010
Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF Receptor Fulltext Access 12 Pages 2010
PlGF Blockade Does Not Inhibit Angiogenesis during Primary Tumor Growth Fulltext Access 12 Pages 2010
Molecular and Cellular Approaches for Diversifying and Extending Optogenetics Fulltext Access 12 Pages 2010
A Global In Vivo Drosophila RNAi Screen Identifies NOT3 as a Conserved Regulator of Heart Function Fulltext Access 12 Pages 2010
Identification of MOAG-4/SERF as a Regulator of Age-Related Proteotoxicity Fulltext Access 12 Pages 2010
Dynamic and Static Interactions between p120 Catenin and E-Cadherin Regulate the Stability of Cell-Cell Adhesion Fulltext Access 12 Pages 2010
Endophilin Functions as a Membrane-Bending Molecule and Is Delivered to Endocytic Zones by Exocytosis Fulltext Access 12 Pages 2010
Stepwise Histone Replacement by SWR1 Requires Dual Activation with Histone H2A.Z and Canonical Nucleosome Fulltext Access 12 Pages 2010
Autophosphorylated CaMKIIα Acts as a Scaffold to Recruit Proteasomes to Dendritic Spines Fulltext Access 12 Pages 2010
Inactivation of Peroxiredoxin I by Phosphorylation Allows Localized H2O2 Accumulation for Cell Signaling Fulltext Access 12 Pages 2010
Comprehensive Polyadenylation Site Maps in Yeast and Human Reveal Pervasive Alternative Polyadenylation Fulltext Access 12 Pages 2010
ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner Fulltext Access 12 Pages 2010
Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids Fulltext Access 12 Pages 2010
Insights into Egg Coat Assembly and Egg-Sperm Interaction from the X-Ray Structure of Full-Length ZP3 Fulltext Access 12 Pages 2010
Immunoproteasomes Preserve Protein Homeostasis upon Interferon-Induced Oxidative Stress Fulltext Access 12 Pages 2010
Influenza Virus M2 Protein Mediates ESCRT-Independent Membrane Scission Fulltext Access 12 Pages 2010
Extensive In Vivo Metabolite-Protein Interactions Revealed by Large-Scale Systematic Analyses Fulltext Access 12 Pages 2010
Peptidoglycan Crosslinking Relaxation Promotes Helicobacter pylori's Helical Shape and Stomach Colonization Fulltext Access 12 Pages 2010
RNA Polymerase II Subunits Link Transcription and mRNA Decay to Translation Fulltext Access 12 Pages 2010
Pausing of RNA Polymerase II Disrupts DNA-Specified Nucleosome Organization to Enable Precise Gene Regulation Fulltext Access 12 Pages 2010
Derivation of Pre-X Inactivation Human Embryonic Stem Cells under Physiological Oxygen Concentrations Fulltext Access 12 Pages 2010
Cellular Strategies for Regulating DNA Supercoiling: A Single-Molecule Perspective Fulltext Access 12 Pages 2010
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations Fulltext Access 12 Pages 2010
Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E Fulltext Access 12 Pages 2010
Periodic Cyclin-Cdk Activity Entrains an Autonomous Cdc14 Release Oscillator Fulltext Access 12 Pages 2010
Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors Fulltext Access 12 Pages 2010
Activation-Induced Cytidine Deaminase Targets DNA at Sites of RNA Polymerase II Stalling by Interaction with Spt5 Fulltext Access 12 Pages 2010
Cell Surface- and Rho GTPase-Based Auxin Signaling Controls Cellular Interdigitation in Arabidopsis Fulltext Access 12 Pages 2010
Nucleoporins Directly Stimulate Expression of Developmental and Cell-Cycle Genes Inside the Nucleoplasm Fulltext Access 12 Pages 2010
Chromatin-Bound Nuclear Pore Components Regulate Gene Expression in Higher Eukaryotes Fulltext Access 12 Pages 2010
A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs Fulltext Access 12 Pages 2010
RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection Fulltext Access 12 Pages 2010
Patronin Regulates the Microtubule Network by Protecting Microtubule Minus Ends Fulltext Access 12 Pages 2010
The Exon Junction Complex Controls the Splicing of mapk and Other Long Intron-Containing Transcripts in Drosophila Fulltext Access 12 Pages 2010
Distinct Protein Domains and Expression Patterns Confer Divergent Axon Guidance Functions for Drosophila Robo Receptors Fulltext Access 12 Pages 2010
Topical and intravenous pilocarpine stimulated accommodation in anesthetized rhesus monkeys Fulltext Access 12 Pages 2010
53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks Fulltext Access 12 Pages 2010
A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth Fulltext Access 12 Pages 2010
Trans-Synaptic Interaction of GluRδ2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum Fulltext Access 12 Pages 2010
Sequential Arrival and Graded Secretion of Sema3F by Olfactory Neuron Axons Specify Map Topography at the Bulb Fulltext Access 12 Pages 2010
Cell Cycle-Dependent Differences in Nuclear Pore Complex Assembly in Metazoa Fulltext Access 12 Pages 2010
A Mammalian Siderophore Synthesized by an Enzyme with a Bacterial Homolog Involved in Enterobactin Production Fulltext Access 12 Pages 2010
Lineage-Specific Transcriptional Regulation of DICER by MITF in Melanocytes Fulltext Access 12 Pages 2010
Helix Unwinding and Base Flipping Enable Human MTERF1 to Terminate Mitochondrial Transcription Fulltext Access 12 Pages 2010
ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks Fulltext Access 12 Pages 2010
Structural Basis for Assembly and Activation of the Heterotetrameric SAGA Histone H2B Deubiquitinase Module Fulltext Access 12 Pages 2010
Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation Fulltext Access 12 Pages 2010
The Vomeronasal Organ Mediates Interspecies Defensive Behaviors through Detection of Protein Pheromone Homologs Fulltext Access 12 Pages 2010
External Lipid PI3P Mediates Entry of Eukaryotic Pathogen Effectors into Plant and Animal Host Cells Fulltext Access 12 Pages 2010
Inhibition of Retrograde Transport Protects Mice from Lethal Ricin Challenge Fulltext Access 12 Pages 2010
NF1 Is a Tumor Suppressor in Neuroblastoma that Determines Retinoic Acid Response and Disease Outcome Fulltext Access 12 Pages 2010
Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue Fulltext Access 13 Pages 2010
Sequence-Dependent Sorting of Recycling Proteins by Actin-Stabilized Endosomal Microdomains Fulltext Access 13 Pages 2010
Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP Fulltext Access 13 Pages 2010
The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove Fulltext Access 13 Pages 2010
Exon Junction Complex Subunits Are Required to Splice Drosophila MAP Kinase, a Large Heterochromatic Gene Fulltext Access 13 Pages 2010
Structural Basis for Actin Assembly, Activation of ATP Hydrolysis, and Delayed Phosphate Release Fulltext Access 13 Pages 2010
A Minimal Midzone Protein Module Controls Formation and Length of Antiparallel Microtubule Overlaps Fulltext Access 13 Pages 2010
TRF2 and Apollo Cooperate with Topoisomerase 2α to Protect Human Telomeres from Replicative Damage Fulltext Access 13 Pages 2010
Crossover Invariance Determined by Partner Choice for Meiotic DNA Break Repair Fulltext Access 13 Pages 2010
Insulin Signaling in Osteoblasts Integrates Bone Remodeling and Energy Metabolism Fulltext Access 13 Pages 2010
RETRACTED: SIRT1 Suppresses β-Amyloid Production by Activating the α-Secretase Gene ADAM10 Fulltext Access 13 Pages 2010
Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming Fulltext Access 13 Pages 2010
Recombination Proteins Mediate Meiotic Spatial Chromosome Organization and Pairing Fulltext Access 13 Pages 2010
Nfix Regulates Fetal-Specific Transcription in Developing Skeletal Muscle Fulltext Access 13 Pages 2010
Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease Fulltext Access 13 Pages 2010
Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis Fulltext Access 13 Pages 2010
Systematic Protein Location Mapping Reveals Five Principal Chromatin Types in Drosophila Cells Fulltext Access 13 Pages 2010
Drosophila Genome-wide Obesity Screen Reveals Hedgehog as a Determinant of Brown versus White Adipose Cell Fate Fulltext Access 13 Pages 2010
A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells Fulltext Access 13 Pages 2010
Retrotranslocation of a Misfolded Luminal ER Protein by the Ubiquitin-Ligase Hrd1p Fulltext Access 13 Pages 2010
Loss of Anion Transport without Increased Sodium Absorption Characterizes Newborn Porcine Cystic Fibrosis Airway Epithelia Fulltext Access 13 Pages 2010
Upf1 ATPase-Dependent mRNP Disassembly Is Required for Completion of Nonsense- Mediated mRNA Decay Fulltext Access 13 Pages 2010
The Fused/Smurf Complex Controls the Fate of Drosophila Germline Stem Cells by Generating a Gradient BMP Response Fulltext Access 13 Pages 2010
The Human PAF1 Complex Acts in Chromatin Transcription Elongation Both Independently and Cooperatively with SII/TFIIS Fulltext Access 13 Pages 2010
Dicer-Independent Primal RNAs Trigger RNAi and Heterochromatin Formation Fulltext Access 13 Pages 2010