Alternative Splicing of Neuronal Differentiation Factor TRF2 Regulated by HNRNPH1/H2 Fulltext Access 9 Pages 2016
The Strip-Hippo Pathway Regulates Synaptic Terminal Formation by Modulating Actin Organization at the Drosophila Neuromuscular Synapses Fulltext Access 9 Pages 2016
Differential Chromosomal Localization of Centromeric Histone CENP-A Contributes to Nematode Programmed DNA Elimination Fulltext Access 9 Pages 2016
NOTCH1 Inhibits Activation of ATM by Impairing the Formation of an ATM-FOXO3a-KAT5/Tip60 Complex Fulltext Access 9 Pages 2016
In Vivo Characterization of Linc-p21 Reveals Functional cis-Regulatory DNA Elements Fulltext Access 9 Pages 2016
C. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan Extension Fulltext Access 9 Pages 2016
Reciprocal Degradation of YME1L and OMA1 Adapts Mitochondrial Proteolytic Activity during Stress Fulltext Access 9 Pages 2016
Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates Fulltext Access 9 Pages 2016
Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin Signaling Fulltext Access 9 Pages 2016
A Positive Regulatory Loop between a Wnt-Regulated Non-coding RNA and ASCL2 Controls Intestinal Stem Cell Fate Fulltext Access 9 Pages 2016
PDK1 Is a Regulator of Epidermal Differentiation that Activates and Organizes Asymmetric Cell Division Fulltext Access 9 Pages 2016
Symmetry Breaking in an Edgeless Epithelium by Fat2-Regulated Microtubule Polarity Fulltext Access 9 Pages 2016
G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells Fulltext Access 9 Pages 2016
Pak4 Is Required during Epithelial Polarity Remodeling through Regulating AJ Stability and Bazooka Retention at the ZA Fulltext Access 9 Pages 2016
Unique Requirement for ESCRT Factors in Flavivirus Particle Formation on the Endoplasmic Reticulum Fulltext Access 9 Pages 2016
Alternative Splice Forms Influence Functions of Whirlin in Mechanosensory Hair Cell Stereocilia Fulltext Access 9 Pages 2016
Smurf1 Inhibits Osteoblast Differentiation, Bone Formation, and Glucose Homeostasis through Serine 148 Fulltext Access 9 Pages 2016
Evidence for an Age-Dependent Decline in Axon Regeneration in the Adult Mammalian Central Nervous System Fulltext Access 9 Pages 2016
Multiphasic and Dynamic Changes in Alternative Splicing during Induction of Pluripotency Are Coordinated by Numerous RNA-Binding Proteins Fulltext Access 9 Pages 2016
Cdc42-Dependent Forgetting Regulates Repetition Effect in Prolonging Memory Retention Fulltext Access 9 Pages 2016
Differences in Strength and Timing of the mtDNA Bottleneck between Zebrafish Germline and Non-germline Cells Fulltext Access 9 Pages 2016
Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity Fulltext Access 9 Pages 2016
The Transcriptional Repressor Polycomb Group Factor 6, PCGF6, Negatively Regulates Dendritic Cell Activation and Promotes Quiescence Fulltext Access 9 Pages 2016
Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth Fulltext Access 9 Pages 2016
Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion Fulltext Access 9 Pages 2016
T-Cell-Specific Deletion of Map3k1 Reveals the Critical Role for Mekk1 and Jnks in Cdkn1b-Dependent Proliferative Expansion Fulltext Access 9 Pages 2016
β-Arrestin-Dependent Dopaminergic Regulation of Calcium Channel Activity in the Axon Initial Segment Fulltext Access 9 Pages 2016
Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells Fulltext Access 9 Pages 2016
Striking Immune Phenotypes in Gene-Targeted Mice Are Driven by a Copy-Number Variant Originating from a Commercially Available C57BL/6 Strain Fulltext Access 9 Pages 2016
Neural Integration Underlying a Time-Compensated Sun Compass in the Migratory Monarch Butterfly Fulltext Access 9 Pages 2016
Replication-Coupled Nucleosome Assembly and Positioning by ATP-Dependent Chromatin-Remodeling Enzymes Fulltext Access 9 Pages 2016
The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division Fulltext Access 9 Pages 2016
Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum Fulltext Access 9 Pages 2016
Reciprocal Regulation between SIRT6 and miR-122 Controls Liver Metabolism and Predicts Hepatocarcinoma Prognosis Fulltext Access 9 Pages 2016
Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G Fulltext Access 9 Pages 2016
Duplication of a Single Neuron in C. elegans Reveals a Pathway for Dendrite Tiling by Mutual Repulsion Fulltext Access 9 Pages 2016
Promotion of RAD51-Mediated Homologous DNA Pairing by the RAD51AP1-UAF1 Complex Fulltext Access 9 Pages 2016
Differential Binding Partners of the Mis18α/β YIPPEE Domains Regulate Mis18 Complex Recruitment to Centromeres Fulltext Access 9 Pages 2016
A Long Non-coding RNA, lncLGR, Regulates Hepatic Glucokinase Expression and Glycogen Storage during Fasting Fulltext Access 9 Pages 2016
NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming Fulltext Access 9 Pages 2016
Ligand-Induced Receptor-like Kinase Complex Regulates Floral Organ Abscission in Arabidopsis Fulltext Access 9 Pages 2016
Human Cytotoxic T Lymphocytes Form Dysfunctional Immune Synapses with B Cells Characterized by Non-Polarized Lytic Granule Release Fulltext Access 10 Pages 2016
Plesiomonas shigelloides exports a lethal cytotoxic-enterotoxin (LCE) by membrane vesicles Fulltext Access 10 Pages 2016
Negative impact of AQP-4 channel inhibition on survival of retinal ganglion cells and glutamate metabolism after crushing optic nerve Fulltext Access 10 Pages 2016
RbAp46/48LIN-53 Is Required for Holocentromere Assembly in Caenorhabditis elegans Fulltext Access 10 Pages 2016
Treatment of alkali-injured cornea by cyclosporine A-loaded electrospun nanofibers - An alternative mode of therapy Fulltext Access 10 Pages 2016
Spinal Microgliosis Due to Resident Microglial Proliferation Is Required for Pain Hypersensitivity after Peripheral Nerve Injury Fulltext Access 10 Pages 2016
The effects of light sources with different spectral structures on ocular axial length in rainbow trout (Oncorhynchus mykiss) Fulltext Access 10 Pages 2016
Metabolic Responses to Dietary Protein Restriction Require an Increase in FGF21 that Is Delayed by the Absence of GCN2 Fulltext Access 10 Pages 2016
Life under pressure: The role of ocular cribriform cells in preventing glaucoma Fulltext Access 10 Pages 2016
Cellular senescence and autophagy in the pathogenesis of chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) Fulltext Access 10 Pages 2016
A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation Fulltext Access 10 Pages 2016
Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases Fulltext Access 10 Pages 2016
Hyperoxia causes diffuse alveolar damage through mechanisms involving upregulation of c-Myc/Bax and enhanced production of reactive oxygen species Fulltext Access 10 Pages 2016
Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1 Fulltext Access 10 Pages 2016
Safety and immunogenicity of a chimpanzee adenovirus-vectored Ebola vaccine in healthy adults: a randomised, double-blind, placebo-controlled, dose-finding, phase 1/2a study Fulltext Access 10 Pages 2016
Infecciones pulmonares en pacientes con VIH 20 años después de la terapia antirretroviral combinada. ¿Qué ha cambiado? Fulltext Access 10 Pages 2016
mTORC1 Inhibition Corrects Neurodevelopmental and Synaptic Alterations in a Human Stem Cell Model of Tuberous Sclerosis Fulltext Access 10 Pages 2016
Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression Fulltext Access 10 Pages 2016
Elucidating MicroRNA Regulatory Networks Using Transcriptional, Post-transcriptional, and Histone Modification Measurements Fulltext Access 10 Pages 2016
SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes Fulltext Access 10 Pages 2016
NIPBL Controls RNA Biogenesis to Prevent Activation of the Stress Kinase PKR Fulltext Access 10 Pages 2016
Uncovering the Number and Clonal Dynamics of Mesp1 Progenitors during Heart Morphogenesis Fulltext Access 10 Pages 2016
5-Hydroxymethylcytosine Marks Sites of DNA Damage and Promotes Genome Stability Fulltext Access 10 Pages 2016
APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication Fulltext Access 10 Pages 2016
Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4 Fulltext Access 10 Pages 2016
Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells Fulltext Access 10 Pages 2016
mGluR-LTD at Excitatory and Inhibitory Synapses in the Lateral Habenula Tunes Neuronal Output Fulltext Access 10 Pages 2016
USP7 Enforces Heterochromatinization of p53 Target Promoters by Protecting SUV39H1 from MDM2-Mediated Degradation Fulltext Access 10 Pages 2016
Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development Fulltext Access 10 Pages 2016
Identification of a Paralog-Specific Notch1 Intracellular Domain Degron Fulltext Access 10 Pages 2016
Atg5 Is Essential for the Development and Survival of Innate Lymphocytes Fulltext Access 10 Pages 2016
Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease Fulltext Access 10 Pages 2016
The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches Fulltext Access 10 Pages 2016
STING Pathway Activation Stimulates Potent Immunity against Acute Myeloid Leukemia Fulltext Access 10 Pages 2016
OVOL2 Maintains the Transcriptional Program of Human Corneal Epithelium by Suppressing Epithelial-to-Mesenchymal Transition Fulltext Access 10 Pages 2016
A Genome-wide RNAi Screen for Microtubule Bundle Formation and Lysosome Motility Regulation in Drosophila S2 Cells Fulltext Access 10 Pages 2016
NAMPT-Mediated NAD+ Biosynthesis in Adipocytes Regulates Adipose Tissue Function and Multi-organ Insulin Sensitivity in Mice Fulltext Access 10 Pages 2016
MAPK-Mediated YAP Activation Controls Mechanical-Tension-Induced Pulmonary Alveolar Regeneration Fulltext Access 10 Pages 2016
A Distinct Lung-Interstitium-Resident Memory CD8+ T Cell Subset Confers Enhanced Protection to Lower Respiratory Tract Infection Fulltext Access 10 Pages 2016
Nascent DNA Proteomics Reveals a Chromatin Remodeler Required for Topoisomerase I Loading at Replication Forks Fulltext Access 10 Pages 2016
Manipulating TLR Signaling Increases the Anti-tumor T Cell Response Induced by Viral Cancer Therapies Fulltext Access 10 Pages 2016
The Kinesin KIF21B Regulates Microtubule Dynamics and Is Essential for Neuronal Morphology, Synapse Function, and Learning and Memory Fulltext Access 10 Pages 2016
Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1 Fulltext Access 10 Pages 2016
Resistance to Antiangiogenic Therapies by Metabolic Symbiosis in Renal Cell Carcinoma PDX Models and Patients Fulltext Access 10 Pages 2016
Centromeric Transcription Regulates Aurora-B Localization and Activation Fulltext Access 10 Pages 2016
Sperm Affects Head Sensory Neuron in Temperature Tolerance of Caenorhabditis elegans Fulltext Access 10 Pages 2016
Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation Fulltext Access 10 Pages 2016
Archaerhodopsin Selectively and Reversibly Silences Synaptic Transmission through Altered pH Fulltext Access 10 Pages 2016
Kinetics of Spontaneous and EF-G-Accelerated Rotation of Ribosomal Subunits Fulltext Access 10 Pages 2016
Structure of Gremlin-2 in Complex with GDF5 Gives Insight into DAN-Family-Mediated BMP Antagonism Fulltext Access 10 Pages 2016