MIWI2 and MILI Have Differential Effects on piRNA Biogenesis and DNA Methylation Fulltext Access 10 Pages 2015
MicroRNA-22 Gates Long-Term Heterosynaptic Plasticity in Aplysia through Presynaptic Regulation of CPEB and Downstream Targets Fulltext Access 10 Pages 2015
Crystal Structure and Activity of the Endoribonuclease Domain of the piRNA Pathway Factor Maelstrom Fulltext Access 10 Pages 2015
Assembly of the Ebola Virus Nucleoprotein from a Chaperoned VP35 Complex Fulltext Access 10 Pages 2015
The SLC7A7 Transporter Identifies Microglial Precursors prior to Entry into the Brain Fulltext Access 10 Pages 2015
Increased Expression of the PI3K Enhancer PIKE Mediates Deficits in Synaptic Plasticity and Behavior in Fragile X Syndrome Fulltext Access 10 Pages 2015
Dissection of Axial-Pore Loop Function during Unfolding and Translocation by a AAA+ Proteolytic Machine Fulltext Access 10 Pages 2015
Hox5 Genes Regulate the Wnt2/2b-Bmp4-Signaling Axis during Lung Development Fulltext Access 10 Pages 2015
Astrocytes Control Food Intake by Inhibiting AGRP Neuron Activity via Adenosine A1 Receptors Fulltext Access 10 Pages 2015
The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity Fulltext Access 10 Pages 2015
Spontaneous Neurotransmitter Release Shapes Dendritic Arbors via Long-Range Activation of NMDA Receptors Fulltext Access 10 Pages 2015
Tiger Swallowtail Genome Reveals Mechanisms for Speciation and Caterpillar Chemical Defense Fulltext Access 10 Pages 2015
Mode of Bioenergetic Metabolism during B Cell Differentiation in the Intestine Determines the Distinct Requirement for Vitamin B1 Fulltext Access 10 Pages 2015
Elongation-Competent Pauses Govern the Fidelity of a Viral RNA-Dependent RNA Polymerase Fulltext Access 10 Pages 2015
An Autoregulatory Mechanism Imposes Allosteric Control on the V(D)J Recombinase by Histone H3 Methylation Fulltext Access 10 Pages 2015
Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer Fulltext Access 10 Pages 2015
H. pylori-Induced DNA Strand Breaks Are Introduced by Nucleotide Excision Repair Endonucleases and Promote NF-κB Target Gene Expression Fulltext Access 10 Pages 2015
Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism Fulltext Access 11 Pages 2015
PIWI Slicing and RNA Elements in Precursors Instruct Directional Primary piRNA Biogenesis Fulltext Access 11 Pages 2015
Targeting LSCs through membrane antigens selectively or preferentially expressed on these cells Fulltext Access 11 Pages 2015
ZwiÄ zek miÄdzy infekcjami wirusowymi we wczesnym okresie życia a późniejszym rozwojem astmy jest niezależny od rodzaju wirusa Fulltext Access 11 Pages 2015
Depression of Serotonin Synaptic Transmission by the Dopamine Precursor L-DOPA Fulltext Access 11 Pages 2015
Efficacy of polymyxins in the treatment of carbapenem-resistant Enterobacteriaceae infections: a systematic review and meta-analysis Fulltext Access 11 Pages 2015
Nationwide and regional incidence of microbiologically confirmed pulmonary tuberculosis in South Africa, 2004–12: a time series analysis Fulltext Access 11 Pages 2015
Intestinal Monocyte-Derived Macrophages Control Commensal-Specific Th17 Responses Fulltext Access 11 Pages 2015
Genome-wide Reconstruction of OxyR and SoxRS Transcriptional Regulatory Networks under Oxidative Stress in Escherichia coli K-12 MG1655 Fulltext Access 11 Pages 2015
Reduction of amyloid-beta levels in mouse eye tissues by intra-vitreally delivered neprilysin Fulltext Access 11 Pages 2015
Direct In Vivo Manipulation and Imaging of Calcium Transients in Neutrophils Identify a Critical Role for Leading-Edge Calcium Flux Fulltext Access 11 Pages 2015
Doublecortin is widely expressed in the developing and adult retina of sharks Fulltext Access 11 Pages 2015
Myofibroblasts in proliferative diabetic retinopathy can originate from infiltrating fibrocytes and through endothelial-to-mesenchymal transition (EndoMT) Fulltext Access 11 Pages 2015
Relationship between rat retinal degeneration and potassium channel KCNQ5 expression Fulltext Access 11 Pages 2015
Iron accumulation in Bruch's membrane and melanosomes of donor eyes with age-related macular degeneration Fulltext Access 11 Pages 2015
A novel imidazopyridine derivative, X22, prevents the retinal ischemia-reperfusion injury via inhibition of MAPKs Fulltext Access 11 Pages 2015
Cloning and the mRNA expression of a C-type lectin with one carbohydrate recognition domain from Fenneropenaeus merguiensis in response to pathogenic inoculation Fulltext Access 11 Pages 2015
Development of a DNA-based microarray for the detection of zoonotic pathogens in rodent species Fulltext Access 11 Pages 2015
Microfluidic droplet-based PCR instrumentation for high-throughput gene expression profiling and biomarker discovery Fulltext Access 11 Pages 2015
Antioxidants, anti-proliferative, anti-inflammatory, anti-diabetic and anti-microbial effects of isolated compounds from Swertia corymbosa (Grieb.) Wight ex C.B. Clark – An in vitro approach Fulltext Access 11 Pages 2015
Testing the Effect of Internal Genes Derived from a Wild-Bird-Origin H9N2 Influenza A Virus on the Pathogenicity of an A/H7N9 Virus Fulltext Access 11 Pages 2015
Manipulation of the Quorum Sensing Signal AI-2 Affects the Antibiotic-Treated Gut Microbiota Fulltext Access 11 Pages 2015
Structure Guided Design of Potent and Selective Ponatinib-Based Hybrid Inhibitors for RIPK1 Fulltext Access 11 Pages 2015
PKA Phosphorylation of NCLX Reverses Mitochondrial Calcium Overload and Depolarization, Promoting Survival of PINK1-Deficient Dopaminergic Neurons Fulltext Access 11 Pages 2015
GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution Fulltext Access 11 Pages 2015
A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells Fulltext Access 11 Pages 2015
An Aminopeptidase in the Drosophila Testicular Niche Acts in Germline Stem Cell Maintenance and Spermatogonial Dedifferentiation Fulltext Access 11 Pages 2015
Amblyomma americanum tick calreticulin binds C1q but does not inhibit activation of the classical complement cascade Fulltext Access 11 Pages 2015
What next-generation sequencing (NGS) technology has enabled us to learn about primary autosomal recessive microcephaly (MCPH) Fulltext Access 11 Pages 2015
Cloning of interleukin-15 gene of Tibetan pig and adjuvant effect of its recombinant plasmids packed with PEG and PEI modified chitosan nanoparticles on immunity of mice to FMD vaccination Fulltext Access 11 Pages 2015
p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen Fulltext Access 11 Pages 2015
Purification, characterization and kinetics of protease inhibitor from fruits of Solanum aculeatissimum Jacq Fulltext Access 11 Pages 2015
Dynamic Recruitment of Functionally Distinct Swi/Snf Chromatin Remodeling Complexes Modulates Pdx1 Activity in Islet β Cells Fulltext Access 11 Pages 2015
Exosome Secretion by the Parasitic Protozoan Leishmania within the Sand Fly Midgut Fulltext Access 11 Pages 2015
Characterization of hematopoietic GATA transcription factor expression in mouse and human dendritic cells Fulltext Access 11 Pages 2015
Genetic Investigation of Tricarboxylic Acid Metabolism during the Plasmodium falciparum Life Cycle Fulltext Access 11 Pages 2015
Adenoviral Vector Vaccination Induces a Conserved Program of CD8+ T Cell Memory Differentiation in Mouse and Man Fulltext Access 11 Pages 2015
Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence Fulltext Access 11 Pages 2015
Engineered Mammalian RNAi Can Elicit Antiviral Protection that Negates the Requirement for the Interferon Response Fulltext Access 11 Pages 2015
RACK1 Promotes Autophagy by Enhancing the Atg14L-Beclin 1-Vps34-Vps15 Complex Formation upon Phosphorylation by AMPK Fulltext Access 11 Pages 2015
Lamin A Is an Endogenous SIRT6 Activator and Promotes SIRT6-Mediated DNA Repair Fulltext Access 11 Pages 2015
CTCF Recruits Centromeric Protein CENP-E to the Pericentromeric/Centromeric Regions of Chromosomes through Unusual CTCF-Binding Sites Fulltext Access 11 Pages 2015
SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase Fulltext Access 11 Pages 2015
Age-Associated Methylation Suppresses SPRY1, Leading to a Failure of Re-quiescence and Loss of the Reserve Stem Cell Pool in Elderly Muscle Fulltext Access 11 Pages 2015
Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling Fulltext Access 11 Pages 2015
SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing Fulltext Access 11 Pages 2015
The Regulatory Machinery of Neurodegeneration in In Vitro Models of Amyotrophic Lateral Sclerosis Fulltext Access 11 Pages 2015
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model Fulltext Access 11 Pages 2015
CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function Fulltext Access 11 Pages 2015
Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins Fulltext Access 11 Pages 2015
Plasmodium Infection Promotes Genomic Instability and AID-Dependent B Cell Lymphoma Fulltext Access 11 Pages 2015
RNAi Interrogation of Dietary Modulation of Development, Metabolism, Behavior, and Aging in C. elegans Fulltext Access 11 Pages 2015
Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration Fulltext Access 11 Pages 2015
The Mitochondrial Metallochaperone SCO1 Is Required to Sustain Expression of the High-Affinity Copper Transporter CTR1 and Preserve Copper Homeostasis Fulltext Access 11 Pages 2015
The Human Mitochondrial DEAD-Box Protein DDX28 Resides in RNA Granules and Functions in Mitoribosome Assembly Fulltext Access 11 Pages 2015
An Inducible Lentiviral Guide RNA Platform Enables the Identification of Tumor-Essential Genes and Tumor-Promoting Mutations In Vivo Fulltext Access 11 Pages 2015
The Mitochondrial Calcium Uniporter Controls Skeletal Muscle Trophism In Vivo Fulltext Access 11 Pages 2015
Hsp70 Forms Antiparallel Dimers Stabilized by Post-translational Modifications to Position Clients for Transfer to Hsp90 Fulltext Access 11 Pages 2015
The Selective Autophagy Receptor p62 Forms a Flexible Filamentous Helical Scaffold Fulltext Access 11 Pages 2015
Neddylation Promotes Ubiquitylation and Release of Ku from DNA-Damage Sites Fulltext Access 11 Pages 2015
Pathways Responsible for Human Autoantibody and Therapeutic Intravenous IgG Activity in Humanized Mice Fulltext Access 11 Pages 2015
Apoptosis Triggers Specific, Rapid, and Global mRNA Decay with 3′ Uridylated Intermediates Degraded by DIS3L2 Fulltext Access 11 Pages 2015
GABA-A Inhibition Shapes the Spatial and Temporal Response Properties of Purkinje Cells in the Macaque Cerebellum Fulltext Access 11 Pages 2015
Production of Extrachromosomal MicroDNAs Is Linked to Mismatch Repair Pathways and Transcriptional Activity Fulltext Access 11 Pages 2015
Helicobacter pylori Infection Causes Characteristic DNA Damage Patterns in Human Cells Fulltext Access 11 Pages 2015
Microtubule-Associated Protein EB3 Regulates IP3 Receptor Clustering and Ca2+ Signaling in Endothelial Cells Fulltext Access 11 Pages 2015
Disabling of the erbB Pathway Followed by IFN-γ Modifies Phenotype and Enhances Genotoxic Eradication of Breast Tumors Fulltext Access 11 Pages 2015
T-type Calcium Channel Regulation of Neural Tube Closure and EphrinA/EPHA Expression Fulltext Access 11 Pages 2015
Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan Anemia and Promotes Lymphomagenesis Fulltext Access 11 Pages 2015