Environmental Temperature Differentially Modulates C. elegans Longevity through a Thermosensitive TRP Channel Fulltext Access 11 Pages 2015
AMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma Fulltext Access 11 Pages 2015
A CRISPR-Based Screen Identifies Genes Essential for West-Nile-Virus-Induced Cell Death Fulltext Access 11 Pages 2015
mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling Fulltext Access 11 Pages 2015
Meta-regulation of Arabidopsis Auxin Responses Depends on tRNA Maturation Fulltext Access 11 Pages 2015
Dependence of Brown Adipose Tissue Function on CD36-Mediated Coenzyme Q Uptake Fulltext Access 11 Pages 2015
A Vitamin D Receptor Selectively Activated by Gemini Analogs Reveals Ligand Dependent and Independent Effects Fulltext Access 11 Pages 2015
Cell-Cycle-Regulated Interaction between Mcm10 and Double Hexameric Mcm2-7 Is Required for Helicase Splitting and Activation during S Phase Fulltext Access 11 Pages 2015
Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy Fulltext Access 11 Pages 2015
Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology Fulltext Access 11 Pages 2015
Salmonella Disrupts Host Endocytic Trafficking by SopD2-Mediated Inhibition of Rab7 Fulltext Access 11 Pages 2015
Context-Specific Effects of TGF-β/SMAD3 in Cancer Are Modulated by the Epigenome Fulltext Access 11 Pages 2015
Respective Functions of Two Distinct Siwi Complexes Assembled during PIWI-Interacting RNA Biogenesis in Bombyx Germ Cells Fulltext Access 11 Pages 2015
Melanin is required for the formation of the multi-cellular conidia in the endophytic fungus Pestalotiopsis microspora Fulltext Access 11 Pages 2015
Characterization of the wzc gene from Pantoea sp. strain PPE7 and its influence on extracellular polysaccharide production and virulence on Pleurotus eryngii Fulltext Access 11 Pages 2015
Novel insight into antimicrobial resistance and sensitivity phenotypes associated to qac and norA genotypes in Staphylococcus aureus Fulltext Access 11 Pages 2015
Diversity and antifungal activity of the endophytic fungi associated with the native medicinal cactus Opuntia humifusa (Cactaceae) from the United States Fulltext Access 11 Pages 2015
The Adh1 gene of the fungus Metarhizium anisopliae is expressed during insect colonization and required for full virulence Fulltext Access 11 Pages 2015
Phenotypic characterization of multidrug-resistant Pseudomonas aeruginosa strains isolated from pediatric patients associated to biofilm formation Fulltext Access 11 Pages 2015
Paradox of plant growth promotion potential of rhizobacteria and their actual promotion effect on growth of barley (Hordeum vulgare L.) under salt stress Fulltext Access 11 Pages 2015
Moroccan study of HLA (-A, -B, -C, -DR, -DQ) polymorphism in 647 unrelated controls: Updating data Fulltext Access 11 Pages 2015
International expert opinion on the management of infection caused by azole-resistant Aspergillus fumigatus Fulltext Access 11 Pages 2015
RhoGTPases - A novel link between cytoskeleton organization and cisplatin resistance Fulltext Access 11 Pages 2015
A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing Fulltext Access 11 Pages 2015
Starvation-Dependent Regulation of Golgi Quality Control Links the TOR Signaling and Vacuolar Protein Sorting Pathways Fulltext Access 11 Pages 2015
Synthetic Quantitative Array Technology Identifies the Ubp3-Bre5 Deubiquitinase Complex as a Negative Regulator of Mitophagy Fulltext Access 11 Pages 2015
Cross-Talk between Carbon Metabolism and the DNA Damage Response in S. cerevisiae Fulltext Access 11 Pages 2015
Bruton’s Tyrosine Kinase Phosphorylates DDX41 and Activates Its Binding of dsDNA and STING to Initiate Type 1 Interferon Response Fulltext Access 11 Pages 2015
Off-Target V(D)J Recombination Drives Lymphomagenesis and Is Escalated by Loss of the Rag2 C Terminus Fulltext Access 11 Pages 2015
MoARG1, MoARG5,6 and MoARG7 involved in arginine biosynthesis are essential for growth, conidiogenesis, sexual reproduction, and pathogenicity in Magnaporthe oryzae Fulltext Access 12 Pages 2015
Methylome-wide Sequencing Detects DNA Hypermethylation Distinguishing Indolent from Aggressive Prostate Cancer Fulltext Access 12 Pages 2015
Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA Fulltext Access 12 Pages 2015
Structural Basis for Molecular Discrimination by a 3′,3′-cGAMP Sensing Riboswitch Fulltext Access 12 Pages 2015
The lncRNA DEANR1 Facilitates Human Endoderm Differentiation by Activating FOXA2 Expression Fulltext Access 12 Pages 2015
Somatic Primary piRNA Biogenesis Driven by cis-Acting RNA Elements and trans-Acting Yb Fulltext Access 12 Pages 2015
Signal loss due to oligomerization in ELISA analysis of amyloid-beta can be recovered by a novel sample pre-treatment method Fulltext Access 12 Pages 2015
Efficient Voronoi volume estimation for DEM simulations of granular materials under confined conditions Fulltext Access 12 Pages 2015
Nucleosome Contact Triggers Conformational Changes of Rpd3S Driving High-Affinity H3K36me Nucleosome Engagement Fulltext Access 12 Pages 2015
NFIL3 Orchestrates the Emergence of Common Helper Innate Lymphoid Cell Precursors Fulltext Access 12 Pages 2015
Systemic treatment with a 5HT1a agonist induces anti-oxidant protection and preserves the retina from mitochondrial oxidative stress Fulltext Access 12 Pages 2015
Ribosome Excursions during mRNA Translocation Mediate Broad Branching of Frameshift Pathways Fulltext Access 12 Pages 2015
Atomic Structure of T6SS Reveals Interlaced Array Essential to Function Fulltext Access 12 Pages 2015
Neuroprotective effect of memantine on the retinal ganglion cells of APPswe/PS1ÎE9 mice and its immunomodulatory mechanisms Fulltext Access 12 Pages 2015
The dynamic sclera: Extracellular matrix remodeling in normal ocular growth and myopia development Fulltext Access 12 Pages 2015
Spatial distributions of AQP5 and AQP0 in embryonic and postnatal mouse lens development Fulltext Access 12 Pages 2015
PEDF counteracts DL-α-aminoadipate toxicity and rescues gliotoxic damages in RPE-free chicken retinal explants Fulltext Access 12 Pages 2015
Stress-Induced CDK5 Activation Disrupts Axonal Transport via Lis1/Ndel1/Dynein Fulltext Access 12 Pages 2015
CTLA4-Ig suppresses development of experimental autoimmune uveitis in the induction and effector phases: Comparison with blockade of interleukin-6 Fulltext Access 12 Pages 2015
TIMP-1 affects the spatial distribution of dendritic processes of second-order neurons in a rat model of Retinitis Pigmentosa Fulltext Access 12 Pages 2015
Rat optic nerve head anatomy within 3D histomorphometric reconstructions of normal control eyes Fulltext Access 12 Pages 2015
Cigarette smoke augments MUC5AC production via the TLR3-EGFR pathway in airway epithelial cells Fulltext Access 12 Pages 2015
A novel outbreak enterovirus D68 strain associated with acute flaccid myelitis cases in the USA (2012–14): a retrospective cohort study Fulltext Access 12 Pages 2015
The eIF4E-Binding Protein 4E-T Is a Component of the mRNA Decay Machinery that Bridges the 5′ and 3′ Termini of Target mRNAs Fulltext Access 12 Pages 2015
Unifying bacteria from decaying wood with various ubiquitous Gibbsiella species as G. acetica sp. nov. based on nucleotide sequence similarities and their acetic acid secretion Fulltext Access 12 Pages 2015
A Mitochondria-Specific Isoform of FASTK Is Present In Mitochondrial RNA Granules and Regulates Gene Expression and Function Fulltext Access 12 Pages 2015
Intratumoral LIGHT Restores Pericyte Contractile Properties and Vessel Integrity Fulltext Access 12 Pages 2015
Cross-Differentiation from the CD8 Lineage to CD4 T Cells in the Gut-Associated Microenvironment with a Nonessential Role of Microbiota Fulltext Access 12 Pages 2015
Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR Fulltext Access 12 Pages 2015
Cleavage-Independent HIV-1 Env Trimers Engineered as Soluble Native Spike Mimetics for Vaccine Design Fulltext Access 12 Pages 2015
Guidance of Drosophila Mushroom Body Axons Depends upon DRL-Wnt Receptor Cleavage in the Brain Dorsomedial Lineage Precursors Fulltext Access 12 Pages 2015
T Cells Integrate Local and Global Cues to Discriminate between Structurally Similar Antigens Fulltext Access 12 Pages 2015
Aurora Kinase B Regulates Telomerase Activity via a Centromeric RNA in Stem Cells Fulltext Access 12 Pages 2015
Post-transcriptional Stabilization of Ucp1 mRNA Protects Mice from Diet-Induced Obesity Fulltext Access 12 Pages 2015
Rapid and Efficient Direct Conversion of Human Adult Somatic Cells into Neural Stem Cells by HMGA2/let-7b Fulltext Access 12 Pages 2015
SART3-Dependent Accumulation of Incomplete Spliceosomal snRNPs in Cajal Bodies Fulltext Access 12 Pages 2015
Genome-wide Analysis of Host-Plasmodium yoelii Interactions Reveals Regulators of the Type I Interferon Response Fulltext Access 12 Pages 2015
Systemic Akt1 Deletion after Tumor Onset in p53−/− Mice Increases Lifespan and Regresses Thymic Lymphoma Emulating p53 Restoration Fulltext Access 12 Pages 2015
The SENP7 SUMO-Protease Presents a Module of Two HP1 Interaction Motifs that Locks HP1 Protein at Pericentric Heterochromatin Fulltext Access 12 Pages 2015
The Crystal Structure of the Drosophila Germline Inducer Oskar Identifies Two Domains with Distinct Vasa Helicase- and RNA-Binding Activities Fulltext Access 12 Pages 2015
Mammary Stem Cell Self-Renewal Is Regulated by Slit2/Robo1 Signaling through SNAI1 and mINSC Fulltext Access 12 Pages 2015
Disrupted PI3K p110δ Signaling Dysregulates Maternal Immune Cells and Increases Fetal Mortality In Mice Fulltext Access 12 Pages 2015
A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins Fulltext Access 12 Pages 2015
Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1 Fulltext Access 12 Pages 2015
Disruption of O-linked N-Acetylglucosamine Signaling Induces ER Stress and β Cell Failure Fulltext Access 12 Pages 2015
Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis Fulltext Access 12 Pages 2015
M-CSF from Cancer Cells Induces Fatty Acid Synthase and PPARβ/δ Activation in Tumor Myeloid Cells, Leading to Tumor Progression Fulltext Access 12 Pages 2015
Cell-Autonomous Regulation of Mu-Opioid Receptor Recycling by Substance P Fulltext Access 12 Pages 2015
The 3D Organization of Chromatin Explains Evolutionary Fragile Genomic Regions Fulltext Access 12 Pages 2015
Lipid Cooperativity as a General Membrane-Recruitment Principle for PH Domains Fulltext Access 12 Pages 2015
ASIC3 Mediates Itch Sensation in Response to Coincident Stimulation by Acid and Nonproton Ligand Fulltext Access 12 Pages 2015
Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia Fulltext Access 12 Pages 2015
Individual Human Cytotoxic T Lymphocytes Exhibit Intraclonal Heterogeneity during Sustained Killing Fulltext Access 12 Pages 2015