Wnt Signaling Regulates Multipolar-to-Bipolar Transition of Migrating Neurons in the Cerebral Cortex Fulltext Access 13 Pages 2015
LncRNA HOTAIR Enhances the Androgen-Receptor-Mediated Transcriptional Program and Drives Castration-Resistant Prostate Cancer Fulltext Access 13 Pages 2015
Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis Fulltext Access 13 Pages 2015
Maintenance of Macrophage Redox Status by ChREBP Limits Inflammation and Apoptosis and Protects against Advanced Atherosclerotic Lesion Formation Fulltext Access 13 Pages 2015
Rad53-Mediated Regulation of Rrm3 and Pif1 DNA Helicases Contributes to Prevention of Aberrant Fork Transitions under Replication Stress Fulltext Access 13 Pages 2015
Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart Fulltext Access 13 Pages 2015
Input- and Cell-Type-Specific Endocannabinoid-Dependent LTD in the Striatum Fulltext Access 13 Pages 2015
An Estrogen-Responsive Module in the Ventromedial Hypothalamus Selectively Drives Sex-Specific Activity in Females Fulltext Access 13 Pages 2015
Transcriptional Profiling of Cutaneous MRGPRD Free Nerve Endings and C-LTMRs Fulltext Access 13 Pages 2015
The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis Fulltext Access 13 Pages 2015
Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA Processing and Ribosome Biogenesis Fulltext Access 13 Pages 2015
An Organellar Nα-Acetyltransferase, Naa60, Acetylates Cytosolic N Termini of Transmembrane Proteins and Maintains Golgi Integrity Fulltext Access 13 Pages 2015
c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells Fulltext Access 13 Pages 2015
Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture Fulltext Access 13 Pages 2015
Degree of Recruitment of DOT1L to MLL-AF9 Defines Level of H3K79 Di- and Tri-methylation on Target Genes and Transformation Potential Fulltext Access 13 Pages 2015
DNA-Damage-Induced Type I Interferon Promotes Senescence and Inhibits Stem Cell Function Fulltext Access 13 Pages 2015
Principles of Long Noncoding RNA Evolution Derived from Direct Comparison of Transcriptomes in 17 Species Fulltext Access 13 Pages 2015
SNAREs Controlling Vesicular Release of BDNF and Development of Callosal Axons Fulltext Access 13 Pages 2015
Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity Fulltext Access 13 Pages 2015
A CDC20-APC/SOX2 Signaling Axis Regulates Human Glioblastoma Stem-like Cells Fulltext Access 13 Pages 2015
In Vivo RNAi Screening Identifies MDA5 as a Significant Contributor to the Cellular Defense against Influenza A Virus Fulltext Access 13 Pages 2015
Individual and Collective Contributions of Chaperoning and Degradation to Protein Homeostasis in E. coli Fulltext Access 13 Pages 2015
A Critical Role for PKR Complexes with TRBP in Immunometabolic Regulation and eIF2α Phosphorylation in Obesity Fulltext Access 13 Pages 2015
Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ Fulltext Access 13 Pages 2015
Nanoscale Architecture of the Axon Initial Segment Reveals an Organized and Robust Scaffold Fulltext Access 13 Pages 2015
Functional analysis of the class II hydrophobin gene HFB2-6 from the biocontrol agent Trichoderma asperellum ACCC30536 Fulltext Access 13 Pages 2015
Genetic analysis of plant endophytic Pseudomonas putida BP25 and chemo-profiling of its antimicrobial volatile organic compounds Fulltext Access 13 Pages 2015
β-Catenin-Dependent Control of Positional Information along the AP Body Axis in Planarians Involves a Teashirt Family Member Fulltext Access 13 Pages 2015
MAPK Phosphatase 5 Expression Induced by Influenza and Other RNA Virus Infection Negatively Regulates IRF3 Activation and Type I Interferon Response Fulltext Access 13 Pages 2015
Single-Cell Telomere-Length Quantification Couples Telomere Length to Meristem Activity and Stem Cell Development in Arabidopsis Fulltext Access 13 Pages 2015
The Parvalbumin/Somatostatin Ratio Is Increased in Pten Mutant Mice and by Human PTEN ASD Alleles Fulltext Access 13 Pages 2015
Membrane Charge Directs the Outcome of F-BAR Domain Lipid Binding and Autoregulation Fulltext Access 13 Pages 2015
Nucleotide Pool Depletion Induces G-Quadruplex-Dependent Perturbation of Gene Expression Fulltext Access 13 Pages 2015
Stem Cell-Specific Mechanisms Ensure Genomic Fidelity within HSCs and upon Aging of HSCs Fulltext Access 13 Pages 2015
Genome-wide RNAi Screening Identifies Protein Modules Required for 40S Subunit Synthesis in Human Cells Fulltext Access 13 Pages 2015
Type I Interferon Transcriptional Signature in Neutrophils and Low-Density Granulocytes Are Associated with Tissue Damage in Malaria Fulltext Access 13 Pages 2015
Plk1 and Mps1 Cooperatively Regulate the Spindle Assembly Checkpoint in Human Cells Fulltext Access 13 Pages 2015
Bidirectional Control of Synaptic GABAAR Clustering by Glutamate and Calcium Fulltext Access 13 Pages 2015
ATM and SIRT6/SNF2H Mediate Transient H2AX Stabilization When DSBs Form by Blocking HUWE1 to Allow Efficient γH2AX Foci Formation Fulltext Access 13 Pages 2015
MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199 Fulltext Access 13 Pages 2015
c-Abl Regulates Proteasome Abundance by Controlling the Ubiquitin-Proteasomal Degradation of PSMA7 Subunit Fulltext Access 13 Pages 2015
Astrocyte-Derived TGF-β1 Accelerates Disease Progression in ALS Mice by Interfering with the Neuroprotective Functions of Microglia and T Cells Fulltext Access 13 Pages 2015
Interaction of CDCP1 with HER2 Enhances HER2-Driven Tumorigenesis and Promotes Trastuzumab Resistance in Breast Cancer Fulltext Access 13 Pages 2015
Two Independent Mushroom Body Output Circuits Retrieve the Six Discrete Components of Drosophila Aversive Memory Fulltext Access 13 Pages 2015
Glucose-Regulated Phosphorylation of the PUF Protein Puf3 Regulates the Translational Fate of Its Bound mRNAs and Association with RNA Granules Fulltext Access 13 Pages 2015
Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation Fulltext Access 13 Pages 2015
VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function Fulltext Access 13 Pages 2015
Splicing-Dependent Trans-synaptic SALM3–LAR-RPTP Interactions Regulate Excitatory Synapse Development and Locomotion Fulltext Access 13 Pages 2015
Rapid Modulation of Axon Initial Segment Length Influences Repetitive Spike Firing Fulltext Access 13 Pages 2015
Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice Fulltext Access 13 Pages 2015
Acetylation of an NB-LRR Plant Immune-Effector Complex Suppresses Immunity Fulltext Access 13 Pages 2015
Chromatin Dynamics and the RNA Exosome Function in Concert to Regulate Transcriptional Homeostasis Fulltext Access 13 Pages 2015
Dectin-1 Regulates Hepatic Fibrosis and Hepatocarcinogenesis by Suppressing TLR4 Signaling Pathways Fulltext Access 13 Pages 2015
The Conformation of Yeast Chromosome III Is Mating Type Dependent and Controlled by the Recombination Enhancer Fulltext Access 13 Pages 2015
Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development Fulltext Access 13 Pages 2015
Two Functionally Distinct Sources of Actin Monomers Supply the Leading Edge of Lamellipodia Fulltext Access 13 Pages 2015
Zygotic Genome Activation Triggers the DNA Replication Checkpoint at the Midblastula Transition Fulltext Access 13 Pages 2015
Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients Fulltext Access 13 Pages 2015
Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement Fulltext Access 13 Pages 2015
Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance Fulltext Access 13 Pages 2015
Circadian Rhythms in Rho1 Activity Regulate Neuronal Plasticity and Network Hierarchy Fulltext Access 13 Pages 2015
Coordinated Regulation of Synaptic Plasticity at Striatopallidal and Striatonigral Neurons Orchestrates Motor Control Fulltext Access 13 Pages 2015
Distinct Sources of Hematopoietic Progenitors Emerge before HSCs and Provide Functional Blood Cells in the Mammalian Embryo Fulltext Access 13 Pages 2015
An Alternatively Spliced Bifunctional Localization Signal Reprograms Human Shugoshin 1 to Protect Centrosomal Instead of Centromeric Cohesin Fulltext Access 13 Pages 2015
PKA Phosphorylates the ATPase Inhibitory Factor 1 and Inactivates Its Capacity to Bind and Inhibit the Mitochondrial H+-ATP Synthase Fulltext Access 13 Pages 2015
DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID Fulltext Access 13 Pages 2015
Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function Fulltext Access 13 Pages 2015
Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export Fulltext Access 13 Pages 2015
Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut Fulltext Access 13 Pages 2015
Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex Fulltext Access 13 Pages 2015
TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy Fulltext Access 13 Pages 2015
Neutrophils Regulate Humoral Autoimmunity by Restricting Interferon-γ Production via the Generation of Reactive Oxygen Species Fulltext Access 13 Pages 2015
Plant-Derived Tick Repellents Activate the Honey Bee Ectoparasitic Mite TRPA1 Fulltext Access 13 Pages 2015
Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal Fulltext Access 14 Pages 2015
DNA Sequence Alignment by Microhomology Sampling during Homologous Recombination Fulltext Access 14 Pages 2015
Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer Fulltext Access 14 Pages 2015
Genomic Alterations in CIITA Are Frequent in Primary Mediastinal Large B Cell Lymphoma and Are Associated with Diminished MHC Class II Expression Fulltext Access 14 Pages 2015
Origin of a Non-Clarke’s Column Division of the Dorsal Spinocerebellar Tract and the Role of Caudal Proprioceptive Neurons in Motor Function Fulltext Access 14 Pages 2015
Global Reprogramming of Host SUMOylation during Influenza Virus Infection Fulltext Access 14 Pages 2015
Impaired LRP6-TCF7L2 Activity Enhances Smooth Muscle Cell Plasticity and Causes Coronary Artery Disease Fulltext Access 14 Pages 2015
Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity Fulltext Access 14 Pages 2015
Chromatin Fibers Are Formed by Heterogeneous Groups of Nucleosomes In Vivo Fulltext Access 14 Pages 2015
ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres Fulltext Access 14 Pages 2015
Ca2+ Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca2+-Dependent Nuclear Gene Expression Fulltext Access 14 Pages 2015
Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch Fulltext Access 14 Pages 2015
Vegfc Regulates Bipotential Precursor Division and Prox1 Expression to Promote Lymphatic Identity in Zebrafish Fulltext Access 14 Pages 2015
CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function Fulltext Access 14 Pages 2015
Recurrent Fusion Genes in Gastric Cancer: CLDN18-ARHGAP26 Induces Loss of Epithelial Integrity Fulltext Access 14 Pages 2015