Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis Fulltext Access 14 Pages 2015
Wallerian Degeneration Is Executed by an NMN-SARM1-Dependent Late Ca2+ Influx but Only Modestly Influenced by Mitochondria Fulltext Access 14 Pages 2015
Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization Fulltext Access 14 Pages 2015
The Yeast Prion [SWI+] Abolishes Multicellular Growth by Triggering Conformational Changes of Multiple Regulators Required for Flocculin Gene Expression Fulltext Access 14 Pages 2015
Toll-like Receptor 2 Activation Promotes Tumor Dendritic Cell Dysfunction by Regulating IL-6 and IL-10 Receptor Signaling Fulltext Access 14 Pages 2015
FMRP-Mediated Axonal Delivery of miR-181d Regulates Axon Elongation by Locally Targeting Map1b and Calm1 Fulltext Access 14 Pages 2015
Differential Regulation of NF-κB-Mediated Proviral and Antiviral Host Gene Expression by Primate Lentiviral Nef and Vpu Proteins Fulltext Access 14 Pages 2015
Compartmentalized AMPK Signaling Illuminated by Genetically Encoded Molecular Sensors and Actuators Fulltext Access 14 Pages 2015
Mir-17∼92 Governs Motor Neuron Subtype Survival by Mediating Nuclear PTEN Fulltext Access 14 Pages 2015
Daytime CLOCK Dephosphorylation Is Controlled by STRIPAK Complexes in Drosophila Fulltext Access 14 Pages 2015
NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells Fulltext Access 14 Pages 2015
Autism-like Deficits in Shank3-Deficient Mice Are Rescued by Targeting Actin Regulators Fulltext Access 14 Pages 2015
CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation Fulltext Access 14 Pages 2015
Jarid2 Coordinates Nanog Expression and PCP/Wnt Signaling Required for Efficient ESC Differentiation and Early Embryo Development Fulltext Access 14 Pages 2015
The Activation of IL-1-Induced Enhancers Depends on TAK1 Kinase Activity and NF-κB p65 Fulltext Access 14 Pages 2015
ROCK-Isoform-Specific Polarization of Macrophages Associated with Age-Related Macular Degeneration Fulltext Access 14 Pages 2015
Influx-Operated Ca2+ Entry via PKD2-L1 and PKD1-L3 Channels Facilitates Sensory Responses to Polymodal Transient Stimuli Fulltext Access 14 Pages 2015
Epigenome Mapping Reveals Distinct Modes of Gene Regulation and Widespread Enhancer Reprogramming by the Oncogenic Fusion Protein EWS-FLI1 Fulltext Access 14 Pages 2015
RNASEK Is a V-ATPase-Associated Factor Required for Endocytosis and the Replication of Rhinovirus, Influenza A Virus, and Dengue Virus Fulltext Access 14 Pages 2015
Replication-Coupled PCNA Unloading by the Elg1 Complex Occurs Genome-wide and Requires Okazaki Fragment Ligation Fulltext Access 14 Pages 2015
miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability Fulltext Access 14 Pages 2015
Chemistry and health beneficial effects of oolong tea and theasinensins Fulltext Access 14 Pages 2015
The BALB/c mouse: Effect of standard vivarium lighting on retinal pathology during aging Fulltext Access 14 Pages 2015
Acetyl-11-keto-β-boswellic acid reduces retinal angiogenesis in a mouse model of oxygen-induced retinopathy Fulltext Access 14 Pages 2015
Hydrophobically-modified poly(vinyl pyrrolidone) as a physically-associative, shear-responsive ophthalmic hydrogel Fulltext Access 14 Pages 2015
The real reason for having a meibomian lipid layer covering the outer surface of the tear film - A review Fulltext Access 14 Pages 2015
Molecular characterization of mouse lens epithelial cell lines and their suitability to study RNA granules and cataract associated genes Fulltext Access 14 Pages 2015
Rat BMSCs initiate retinal endogenous repair through NGF/TrkA signaling Fulltext Access 14 Pages 2015
Thrombospondin-1 induces differential response in human corneal and conjunctival epithelial cells lines under in vitro inflammatory and apoptotic conditions Fulltext Access 14 Pages 2015
Synthetic and endogenous cannabinoids protect retinal neurons from AMPA excitotoxicity in vivo, via activation of CB1 receptors: Involvement of PI3K/Akt and MEK/ERK signaling pathways Fulltext Access 14 Pages 2015
Clinical value of whole-genome sequencing of Mycobacterium tuberculosis Fulltext Access 14 Pages 2015
Analysis of p53 Transactivation Domain Mutants Reveals Acad11 as a Metabolic Target Important for p53 Pro-Survival Function Fulltext Access 14 Pages 2015
Construction and Synergistic Effect of Recombinant Yeast Co-expressing Pig IL-2/4/6 on Immunity of Piglets to PRRS Vaccination Fulltext Access 14 Pages 2015
Isolation and characterization of multifunctional Streptomyces species with antimicrobial, nematicidal and phytohormone activities from marine environments in Egypt Fulltext Access 14 Pages 2015
Identification of genes induced by Fusarium graminearum inoculation in the resistant durum wheat line Langdon(Dic-3A)10 and the susceptible parental line Langdon Fulltext Access 14 Pages 2015
Modeling mixed boundary conditions in a Hilbert space with the complex variable boundary element method (CVBEM) Fulltext Access 14 Pages 2015
Notch2 Is Required for Inflammatory Cytokine-Driven Goblet Cell Metaplasia in the Lung Fulltext Access 14 Pages 2015
Developmentally Regulated Post-translational Modification of Nucleoplasmin Controls Histone Sequestration and Deposition Fulltext Access 14 Pages 2015
cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels Fulltext Access 14 Pages 2015
Amino Acid Activation of mTORC1 by a PB1-Domain-Driven Kinase Complex Cascade Fulltext Access 14 Pages 2015
Perturbation of Ribosome Biogenesis Drives Cells into Senescence through 5S RNP-Mediated p53 Activation Fulltext Access 14 Pages 2015
Metabolic Reprogramming of Cancer-Associated Fibroblasts by IDH3α Downregulation Fulltext Access 14 Pages 2015
The Rab2A GTPase Promotes Breast Cancer Stem Cells and Tumorigenesis via Erk Signaling Activation Fulltext Access 14 Pages 2015
APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer Fulltext Access 14 Pages 2015
Deregulation of the Ras-Erk Signaling Axis Modulates the Enhancer Landscape Fulltext Access 14 Pages 2015
Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney Fulltext Access 14 Pages 2015
Bacterial c-di-GMP Affects Hematopoietic Stem/Progenitors and Their Niches through STING Fulltext Access 14 Pages 2015
High-Resolution Profiling of Drosophila Replication Start Sites Reveals a DNA Shape and Chromatin Signature of Metazoan Origins Fulltext Access 14 Pages 2015
BDNF Reduces Toxic Extrasynaptic NMDA Receptor Signaling via Synaptic NMDA Receptors and Nuclear-Calcium-Induced Transcription of inhba/Activin A Fulltext Access 14 Pages 2015
Intravacuolar Membranes Regulate CD8 T Cell Recognition of Membrane-Bound Toxoplasma gondii Protective Antigen Fulltext Access 14 Pages 2015
Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex Fulltext Access 14 Pages 2015
The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts Fulltext Access 14 Pages 2015
A Polyadenylation-Dependent 3′ End Maturation Pathway Is Required for the Synthesis of the Human Telomerase RNA Fulltext Access 14 Pages 2015
Obesity Drives Th17 Cell Differentiation by Inducing the Lipid Metabolic Kinase, ACC1 Fulltext Access 14 Pages 2015
Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation Fulltext Access 14 Pages 2015
The CPEB3 Protein Is a Functional Prion that Interacts with the Actin Cytoskeleton Fulltext Access 14 Pages 2015
FAK Mediates a Compensatory Survival Signal Parallel to PI3K-AKT in PTEN-Null T-ALL Cells Fulltext Access 14 Pages 2015
The Transcription Factor E4F1 Coordinates CHK1-Dependent Checkpoint and Mitochondrial Functions Fulltext Access 14 Pages 2015
mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation Fulltext Access 14 Pages 2015
Genome-Derived Cytosolic DNA Mediates Type I Interferon-Dependent Rejection of B Cell Lymphoma Cells Fulltext Access 14 Pages 2015
Identification of a Non-Gatekeeper Hot Spot for Drug-Resistant Mutations in mTOR Kinase Fulltext Access 14 Pages 2015
Cellular Levels of Signaling Factors Are Sensed by β-actin Alleles to Modulate Transcriptional Pulse Intensity Fulltext Access 14 Pages 2015
ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes Fulltext Access 14 Pages 2015
An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions Fulltext Access 14 Pages 2015
Integrated Genomics of Crohn’s Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy Fulltext Access 14 Pages 2015
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance Fulltext Access 14 Pages 2015
Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1low Monocytes Fulltext Access 14 Pages 2015
Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells Fulltext Access 14 Pages 2015
LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes Fulltext Access 15 Pages 2015
Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression Fulltext Access 15 Pages 2015
ER-Coordinated Activities of Rab22a and Rab5a Drive Phagosomal Compaction and Intracellular Processing of Borrelia burgdorferi by Macrophages Fulltext Access 15 Pages 2015
Microtubule Destabilizer KIF2A Undergoes Distinct Site-Specific Phosphorylation Cascades that Differentially Affect Neuronal Morphogenesis Fulltext Access 15 Pages 2015
Quantitative Proteomics Identifies Serum Response Factor Binding Protein 1 as a Host Factor for Hepatitis C Virus Entry Fulltext Access 15 Pages 2015
Focal MMP-2 and MMP-9 Activity at the Blood-Brain Barrier Promotes Chemokine-Induced Leukocyte Migration Fulltext Access 15 Pages 2015
ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis Fulltext Access 15 Pages 2015
Deletion of Macrophage Vitamin D Receptor Promotes Insulin Resistance and Monocyte Cholesterol Transport to Accelerate Atherosclerosis in Mice Fulltext Access 15 Pages 2015
Circulating Th1-Cell-type Tfh Cells that Exhibit Impaired B Cell Help Are Preferentially Activated during Acute Malaria in Children Fulltext Access 15 Pages 2015
Vitamin D3 Induces Tolerance in Human Dendritic Cells by Activation of Intracellular Metabolic Pathways Fulltext Access 15 Pages 2015
Mondo-Mlx Mediates Organismal Sugar Sensing through the Gli-Similar Transcription Factor Sugarbabe Fulltext Access 15 Pages 2015
Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ Fulltext Access 15 Pages 2015
A Floor-Plate Extracellular Protein-Protein Interaction Screen Identifies Draxin as a Secreted Netrin-1 Antagonist Fulltext Access 15 Pages 2015
Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells Fulltext Access 15 Pages 2015
Heparan Sulfate Proteoglycans Regulate Fgf Signaling and Cell Polarity during Collective Cell Migration Fulltext Access 15 Pages 2015
The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin Fulltext Access 15 Pages 2015
Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer Fulltext Access 15 Pages 2015
DDX60 Is Involved in RIG-I-Dependent and Independent Antiviral Responses, and Its Function Is Attenuated by Virus-Induced EGFR Activation Fulltext Access 15 Pages 2015
Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity Fulltext Access 15 Pages 2015
A Primary Role for the Tsix lncRNA in Maintaining Random X-Chromosome Inactivation Fulltext Access 15 Pages 2015
Elevated CaMKIIα and Hyperphosphorylation of Homer Mediate Circuit Dysfunction in a Fragile X Syndrome Mouse Model Fulltext Access 15 Pages 2015
Intratumoral Myeloid Cells Regulate Responsiveness and Resistance to Antiangiogenic Therapy Fulltext Access 15 Pages 2015
miR-199a Links MeCP2 with mTOR Signaling and Its Dysregulation Leads to Rett Syndrome Phenotypes Fulltext Access 15 Pages 2015
Set1 and MLL1/2 Target Distinct Sets of Functionally Different Genomic Loci In Vivo Fulltext Access 15 Pages 2015
A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species Fulltext Access 15 Pages 2015