Definition of the R-superfamily of conotoxins: Structural convergence of helix-loop-helix peptidic scaffolds Fulltext Access 21 Pages 2018
IL-4 and serum amyloid P inversely regulate fibrocyte differentiation by targeting store-operated Ca2+ channels Fulltext Access 21 Pages 2018
Alamandine injected into the paraventricular nucleus increases blood pressure and sympathetic activation in spontaneously hypertensive rats Fulltext Access 21 Pages 2018
Irreversible proteasome inhibition with carfilzomib as first line therapy in patients with newly diagnosed multiple myeloma: Early in vivo cardiovascular effects Fulltext Access 21 Pages 2018
Interleukin-15 derived from Guanylin-GC-C-expressing macrophages inhibits fatty acid synthase in adipocytes Fulltext Access 21 Pages 2018
Urolithin A shows anti-atherosclerotic activity via activation of class B scavenger receptor and activation of Nef2 signaling pathway Fulltext Access 21 Pages 2018
miR-133b and miR-199b knockdown attenuate TGF-β1-induced epithelial to mesenchymal transition and renal fibrosis by targeting SIRT1 in diabetic nephropathy Fulltext Access 21 Pages 2018
TNF-alpha and TNF-R1 regulate bupivacaine-induced apoptosis in spinal cord dorsal root ganglion neuron Fulltext Access 22 Pages 2018
Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes Fulltext Access 22 Pages 2018
Danshensu prevents hypoxic pulmonary hypertension in rats by inhibiting the proliferation of pulmonary artery smooth muscle cells via TGF-β-smad3-associated pathway Fulltext Access 22 Pages 2018
The role of Ca2+ in cell death caused by oxidative glutamate toxicity and ferroptosis Fulltext Access 22 Pages 2018
MAPKs-mediated modulation of the myocyte voltage-gated K+ channels is involved in ethanol-induced rat coronary arterial contraction Fulltext Access 22 Pages 2018
Anticonvulsive effects of protodioscin against pilocarpine-induced epilepsy Fulltext Access 22 Pages 2018
Effectiveness of memantine on depression-like behavior, memory deficits and brain mRNA levels of BDNF and TrkB in rats subjected to repeated unpredictable stress Fulltext Access 22 Pages 2018
Spontaneous activity, singly bound states and the impact of alpha1Phe64 mutation on GABAAR gating in the novel kinetic model based on the single-channel recordings Fulltext Access 22 Pages 2018
The effect of N-acetylcysteine or bupropion on methamphetamine self-administration and methamphetamine-triggered reinstatement of female rats Fulltext Access 22 Pages 2018
Thioredoxin-1 downregulation in the nucleus accumbens promotes methamphetamine-primed reinstatement in mice Fulltext Access 22 Pages 2018
Adenine accelerated the diabetic wound healing by PPAR delta and angiogenic regulation Fulltext Access 22 Pages 2018
Glucagon-like peptide-1 (GLP-1) action in the mouse area postrema neurons Fulltext Access 22 Pages 2018
Triintsin, a human pathogenic fungus-derived defensin with broad-spectrum antimicrobial activity Fulltext Access 22 Pages 2018
Blood-brain barrier integrity in a mouse model of Alzheimer's disease with or without acute 3D6 immunotherapy Fulltext Access 22 Pages 2018
Transcriptomic discovery and comparative analysis of neuropeptide precursors in sea cucumbers (Holothuroidea) Fulltext Access 22 Pages 2018
Expression pattern of delta-like 1 homolog in developing sympathetic neurons and chromaffin cells Fulltext Access 22 Pages 2018
Nicotine modulates contextual fear extinction through changes in ventral hippocampal GABAergic function Fulltext Access 22 Pages 2018
Perï¬uorooctanesulfonate induces neuroinflammation through the secretion of TNF-α mediated by the JAK2/STAT3 pathway Fulltext Access 22 Pages 2018
Application of E75 peptide vaccine in breast cancer patients: A systematic review and meta-analysis Fulltext Access 23 Pages 2018
Monitoring Ca2+ elevations in individual astrocytes upon local release of amyloid beta in acute brain slices Fulltext Access 23 Pages 2018
Nociceptin/orphanin FQ opioid peptide (NOP) receptor and µ-opioid peptide (MOP) receptors both contribute to the anti-hypersensitive effect of cebranopadol in a rat model of arthritic pain Fulltext Access 23 Pages 2018
MiR-182 alleviates the development of cyanotic congenital heart disease by suppressing HES1 Fulltext Access 23 Pages 2018
Role of orexins in the central and peripheral regulation of glucose homeostasis: Evidences & mechanisms Fulltext Access 23 Pages 2018
Knockdown of NLRC5 inhibits renal fibroblast activation via modulating TGF-β1/Smad signaling pathway Fulltext Access 23 Pages 2018
The potential role of substance P in brainstem homeostatic control in the pathogenesis of sudden infant death syndrome (SIDS) Fulltext Access 23 Pages 2018
Ropivacaine relieves pain and prevents chondrocyte degradation probably through Calcineurin/NFAT1 signaling pathway in osteoarthritis rats Fulltext Access 23 Pages 2018
Cannabinoid-1 receptor neutral antagonist reduces binge-like alcohol consumption and alcohol-induced accumbal dopaminergic signaling Fulltext Access 23 Pages 2018
Lacosamide protects striatal and hippocampal neurons from in vitro ischemia without altering physiological synaptic plasticity Fulltext Access 23 Pages 2018
Dexmedetomidine ameliorates lidocaine-induced spinal neurotoxicity via inhibiting glutamate release and the PKC pathway Fulltext Access 23 Pages 2018
Computational design and experimental characterization of a novel β-common receptor inhibitory peptide Fulltext Access 23 Pages 2018
Ciprofloxacin-mediated induction of S-phase cell cycle arrest and apoptosis in COLO829 melanoma cells Fulltext Access 23 Pages 2018
Comparative expression analyses of bone morphogenetic protein 4 (BMP4) expressions in muscles of tilapia and common carp indicate that BMP4 plays a role in the intermuscular bone distribution in a dose-dependent manner Fulltext Access 23 Pages 2018
Exercise decreases BACE and APP levels in the hippocampus of a rat model of Alzheimer's disease Fulltext Access 23 Pages 2018
A Comparative study for striatal-direct and -indirect pathway neurons to DA depletion-induced lesion in a PD rat model Fulltext Access 23 Pages 2018
Aminochrome decreases NGF, GDNF and induces neuroinflammation in organotypic midbrain slice cultures Fulltext Access 24 Pages 2018
Role of Oleanolic acid in maintaining BBB integrity by targeting p38MAPK/VEGF/Src signaling pathway in rat model of subarachnoid hemorrhage Fulltext Access 24 Pages 2018
Scopolamine-induced passive avoidance memory retrieval deficit is accompanied with hippocampal MMP2, MMP-9 and MAPKs alteration Fulltext Access 24 Pages 2018
Anticonvulsant activities of α-asaronol ((E)-3â²-hydroxyasarone), an active constituent derived from α-asarone Fulltext Access 24 Pages 2018
A protective role of Gαq-RGS2 loop activator on streptozotocin induced diabetic complications in rats: An independent on elevated serum glucose level modulation Fulltext Access 24 Pages 2018
Ventrolateral orbital cortex oxytocin attenuates neuropathic pain through periaqueductal gray opioid receptor Fulltext Access 24 Pages 2018
Memantine decreases neuronal degeneration in young rats submitted to LiCl-pilocarpine-induced status epilepticus Fulltext Access 24 Pages 2018
Neurotoxicity screening of new psychoactive substances (NPS): Effects on neuronal activity in rat cortical cultures using microelectrode arrays (MEA) Fulltext Access 24 Pages 2018
Expression levels of interferon-É£ and type 2 deiodinase in patients diagnosed with recurrent depressive disorders Fulltext Access 24 Pages 2018
The iron pro-chelator BHAPI attenuates glutamate-induced oxidative stress via Wnt-β/catenin pathway in HT22 cells Fulltext Access 24 Pages 2018
Postconditioning with repeated mild hypoxia protects neonatal hypoxia-ischemic rats against brain damage and promotes rehabilitation of brain function Fulltext Access 24 Pages 2018
Amygdala stimulation promotes recovery of behavioral performance in a spatial memory task and increases GAP-43 and MAP-2 in the hippocampus and prefrontal cortex of male rats Fulltext Access 24 Pages 2018
GABAergic interneurons: The orchestra or the conductor in fear learning and memory? Fulltext Access 24 Pages 2018
PERK as a hub of multiple pathogenic pathways leading to memory deficits and neurodegeneration in Alzheimer's disease Fulltext Access 24 Pages 2018
Lysosomal exocytosis of ATP is coupled to P2Y2 receptor in marginal cells in the stria vascular in neonatal rats Fulltext Access 24 Pages 2018
Repeated exposure to 3,4-methylenedioxypyrovalerone and cocaine produces locomotor sensitization with minimal effects on brain monoamines Fulltext Access 24 Pages 2018
Osteoanabolic activity of whey-derived anti-oxidative (MHIRL and YVEEL) and angiotensin-converting enzyme inhibitory (YLLF, ALPMHIR, IPA and WLAHK) bioactive peptides Fulltext Access 24 Pages 2018
Betulinic acid alleviates myocardial hypoxia/reoxygenation injury via inducing Nrf2/HO-1 and inhibiting p38 and JNK pathways Fulltext Access 24 Pages 2018
1,8-cineol inhibits the Wnt/β-catenin signaling pathway through GSK-3 dephosphorylation in nasal polyps of chronic rhinosinusitis patients Fulltext Access 24 Pages 2018
Expression of recombinant α-toxin BmKM9 from scorpion Buthus martensii Karsch and its functional characterization on sodium channels Fulltext Access 24 Pages 2018
Methyl cinnamate alleviated CCI-induced upregualtion of spinal AMPA receptors and pain hypersensitivity by targeting AMPK Fulltext Access 24 Pages 2018
Blockade of the orexin receptors in the CA1 region of hippocampus decreased the lateral hypothalamic-induced antinociceptive responses in the model of orofacial formalin test in the rats Fulltext Access 24 Pages 2018
Role of statins and mevalonate pathway on impaired HDAC2 activity induced by oxidative stress in human airway epithelial cells Fulltext Access 24 Pages 2018
Long noncoding RNA SNHG16 reduced ketamine-induced neurotoxicity in human embryonic stem cell-derived neurons Fulltext Access 25 Pages 2018
AMPA-induced extracellular Zn2+ influx into nigral dopaminergic neurons causes movement disorder in rats Fulltext Access 25 Pages 2018
Metabolic effects of manganese in the nematode Caenorhabditis elegans through DAergic pathway and transcription factors activation Fulltext Access 25 Pages 2018
Inhibition of catechol-O-methyltransferase in the cynomolgus monkey by opicapone after acute and repeated administration Fulltext Access 25 Pages 2018
The importance of chemokines in neuropathic pain development and opioid analgesic potency Fulltext Access 25 Pages 2018
Combined treatment with aripiprazole and antidepressants reversed some MK-801-induced schizophrenia-like symptoms in mice Fulltext Access 25 Pages 2018
The role of (E)-6-chloro-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-2-styrylquinazolin-4(3H)-one in the modulation of cannabinoidergic system. A pilot study Fulltext Access 25 Pages 2018
Cab45s inhibits neuronal apoptosis following intracerebral hemorrhage in adult rats Fulltext Access 25 Pages 2018
Expression of the adhesion G protein-coupled receptor A2 (adgra2) during Xenopus laevis development Fulltext Access 25 Pages 2018
Current status of muscarinic M1 and M4 receptors as drug targets for neurodegenerative diseases Fulltext Access 25 Pages 2018
Glucagon-like receptor 1 agonists and DPP-4 inhibitors: Anti-diabetic drugs with anti-stroke potential Fulltext Access 25 Pages 2018
Histamine-deficient mice do not respond to the antidepressant-like effects of oleoylethanolamide Fulltext Access 25 Pages 2018
Heat shock protein 70 suppresses neuroinflammation induced by α-synuclein in astrocytes Fulltext Access 25 Pages 2018
Pharmacological activation of mGlu4 and mGlu7 receptors, by LSP2-9166, reduces ethanol consumption and relapse in rat Fulltext Access 25 Pages 2018
The pro-apoptotic protein Bmf co-operates with Bim and Puma in neuron death induced by β-amyloid or NGF deprivation Fulltext Access 25 Pages 2018
Fingolimod anti-inflammatory and neuroprotective effects modulation of RAGE axis in multiple sclerosis patients Fulltext Access 25 Pages 2018
P2X7 purinergic receptors participate in the expression and extinction processes of contextual fear conditioning memory in mice Fulltext Access 25 Pages 2018
Sensorimotor gating deficits and effects of antipsychotics on the hyperactivity in VGF-overexpressing mice Fulltext Access 25 Pages 2018
LncRNA MIAT facilitated BM-MSCs differentiation into endothelial cells and restored erectile dysfunction via targeting miR-200a in a rat model of erectile dysfunction Fulltext Access 25 Pages 2018
Long noncoding RNA VIM-AS1 promotes colorectal cancer progression and metastasis by inducing EMT Fulltext Access 25 Pages 2018
Oxaliplatin treatment impairs extension of sensory neuron neurites in vitro through miR-204 overexpression Fulltext Access 25 Pages 2018
Fibroblast growth factor 20 is protective towards dopaminergic neurons in vivo in a paracrine manner Fulltext Access 25 Pages 2018
Alpinumisoflavone rescues glucocorticoid-induced apoptosis of osteocytes via suppressing Nox2-dependent ROS generation Fulltext Access 25 Pages 2018
Phosphatidylinositol 3 kinase (PI3K) modulates manganese homeostasis and manganese-induced cell signaling in a murine striatal cell line Fulltext Access 25 Pages 2018
Prenatal phthalate exposure and language development in toddlers from the Odense Child Cohort Fulltext Access 25 Pages 2018