C-terminal hydrazide modification changes the spinal antinociceptive profiles of endomorphins in mice Fulltext Access 25 Pages 2018
Ginkgolide K promotes astrocyte proliferation and migration after oxygen-glucose deprivation via inducing protective autophagy through the AMPK/mTOR/ULK1 signaling pathway Fulltext Access 25 Pages 2018
Local administration of mangiferin prevents experimental inflammatory mechanical hyperalgesia through CINC-1/epinephrine/PKA pathway and TNF-α inhibition Fulltext Access 25 Pages 2018
Alantolactone suppresses APOC3 expression and alters lipid homeostasis in L02 liver cells Fulltext Access 25 Pages 2018
Suppression of TLR4 activation by resveratrol is associated with STAT3 and Akt inhibition in oxidized low-density lipoprotein-activated platelets Fulltext Access 25 Pages 2018
Dehydroeffusol inhibits viability and epithelial-mesenchymal transition through the Hedgehog and Akt/mTOR signaling pathways in neuroblastoma cells Fulltext Access 25 Pages 2018
The role of verapamil and SL-327 in morphine- and ethanol-induced state-dependent and cross state-dependent memory Fulltext Access 25 Pages 2018
Selective peroxisome proliferator-activated receptor-α modulator K-877 regulates the expression of ATP-binding cassette transporter A1 in pancreatic beta cells Fulltext Access 25 Pages 2018
Pentoxifylline inhibits angiogenesis via decreasing Dll4 and Notch1 expression in mouse proepicardial explant cultures Fulltext Access 25 Pages 2018
20(S)-25-methoxyl-dammarane-3β,12β,20-triol attenuates endoplasmic reticulum stress via ERK/MAPK signaling pathway Fulltext Access 25 Pages 2018
Exendin-4 partly ameliorates - hyperglycemia-mediated tissue damage in lungs of streptozotocin-induced diabetic mice Fulltext Access 25 Pages 2018
1â¯mA cathodal tDCS shows excitatory effects in children and adolescents: Insights from TMS evoked N100 potential Fulltext Access 25 Pages 2018
Antineoplastic activity of isoliquiritigenin, a chalcone compound, in androgen-independent human prostate cancer cells linked to G2/M cell cycle arrest and cell apoptosis Fulltext Access 25 Pages 2018
Indirubin-3'-oxime suppresses human cholangiocarcinoma through cell-cycle arrest and apoptosis Fulltext Access 25 Pages 2018
Role of paraventricular hypothalamic dopaminergic D1 receptors in food intake regulation of food-deprived rats Fulltext Access 25 Pages 2018
LOX-1 mediated phenotypic switching of pulmonary arterial smooth muscle cells contributes to hypoxic pulmonary hypertension Fulltext Access 25 Pages 2018
Combined aerosolized Toll-like receptor ligands are an effective therapeutic agent against influenza pneumonia when co-administered with oseltamivir Fulltext Access 25 Pages 2018
Effects of saccharin supplementation on body weight, sweet receptor mRNA expression and appetite signals regulation in post-weanling rats Fulltext Access 25 Pages 2018
Treatment with galectin-1 eye drops regulates mast cell degranulation and attenuates the severity of conjunctivitis Fulltext Access 25 Pages 2018
The regulatory effects of metformin on the [SNAIL/miR-34]:[ZEB/miR-200] system in the epithelial-mesenchymal transition(EMT) for colorectal cancer(CRC) Fulltext Access 26 Pages 2018
Osthole alleviated diabetic neuropathic pain mediated by the P2X4 receptor in dorsal root ganglia Fulltext Access 26 Pages 2018
Scopoletin inhibits α-glucosidase in vitro and alleviates postprandial hyperglycemia in mice with diabetes Fulltext Access 26 Pages 2018
Mirabegron, a β3-adrenoceptor agonist reduced platelet aggregation through cyclic adenosine monophosphate accumulation Fulltext Access 26 Pages 2018
Inhibition of microRNA-505 suppressed MPP+â¯-induced cytotoxicity of SHSY5Y cells in an in vitro Parkinson's disease model Fulltext Access 26 Pages 2018
Recombinant IgG1 Fc hexamers block cytotoxicity and pathological changes in experimental in vitro and rat models of neuromyelitis optica Fulltext Access 26 Pages 2018
Systemic blockade of LPA1/3 lysophosphatidic acid receptors by ki16425 modulates the effects of ethanol on the brain and behavior Fulltext Access 26 Pages 2018
Mechanisms of sustained long-term weight loss after RYGB: α-MSH is a key factor Fulltext Access 26 Pages 2018
Rutin, a quercetin glycoside, alleviates acute endotoxemic kidney injury in C57BL/6 mice via suppression of inflammation and up-regulation of antioxidants and SIRT1 Fulltext Access 26 Pages 2018
Regulatory effect of nicotine on the differentiation of Th1, Th2 and Th17 lymphocyte subsets in patients with rheumatoid arthritis Fulltext Access 26 Pages 2018
Casticin inhibits PDGF-induced proliferation and migration of airway smooth muscle cells Fulltext Access 26 Pages 2018
Fluorinated phenmetrazine “legal highs” act as substrates for high-affinity monoamine transporters of the SLC6 family Fulltext Access 26 Pages 2018
Anti-IL-12/IL-23p40 antibody ameliorates dermatitis and skin barrier dysfunction in mice with imiquimod-induced psoriasis-like dermatitis Fulltext Access 26 Pages 2018
Forebrain glutamate uptake and behavioral parameters are altered in adult zebrafish after the induction of Status Epilepticus by kainic acid Fulltext Access 26 Pages 2018
Melatonin promotes neuroprotection of induced pluripotent stem cells-derived neural stem cells subjected to H2O2-induced injury in vitro Fulltext Access 26 Pages 2018
Assessing mercury intoxication in isolated/remote populations: Increased S100B mRNA in blood in exposed riverine inhabitants of the Amazon Fulltext Access 26 Pages 2018
Schisandrol B promotes liver regeneration after partial hepatectomy in mice Fulltext Access 26 Pages 2018
ISG'ylation increases stability of numerous proteins including Stat1, which prevents premature termination of immune response in LPS-stimulated microglia Fulltext Access 26 Pages 2018
Cyclophosphamide-modified murine peritoneal macrophages induce CD4+ T contrasuppressor cells that protect contact sensitivity T effector cells from suppression Fulltext Access 26 Pages 2018
The glucagon-like peptide-1 analogue liraglutide promotes autophagy through the modulation of 5â²-AMP-activated protein kinase in INS-1 β-cells under high glucose conditions Fulltext Access 26 Pages 2018
MicroRNA-17 impairs glucose metabolism in insulin-resistant skeletal muscle via repressing glucose transporter 4 expression Fulltext Access 26 Pages 2018
Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells Fulltext Access 26 Pages 2018
EBI2 regulates pro-inflammatory signalling and cytokine release in astrocytes Fulltext Access 26 Pages 2018
Urate mitigates oxidative stress and motor neuron toxicity of astrocytes derived from ALS-linked SOD1G93A mutant mice Fulltext Access 26 Pages 2018
The ferroxidase ceruloplasmin influences Reelin processing, cofilin phosphorylation and neuronal organization in the developing brain Fulltext Access 26 Pages 2018
Dual effects of insect nAChR chaperone RIC-3 on hybrid receptor: Promoting assembly on endoplasmic reticulum but suppressing transport to plasma membrane on Xenopus oocytes Fulltext Access 26 Pages 2018
Enhanced angiotensin II induced sodium appetite in renovascular hypertensive rats Fulltext Access 26 Pages 2018
Bradykinin-potentiating PEPTIDE-10C, an argininosuccinate synthetase activator, protects against H2O2-induced oxidative stress in SH-SY5Y neuroblastoma cells Fulltext Access 26 Pages 2018
Interplay between 5-HT2C and 5-HT1A receptors in the dorsal periaqueductal gray in the modulation of fear-induced antinociception in mice Fulltext Access 26 Pages 2018
Involvement of neuronal and glial activities in control of the extracellular d-serine concentrations by the AMPA glutamate receptor in the mouse medial prefrontal cortex Fulltext Access 26 Pages 2018
Chloride cotransporter KCC2 is essential for GABAergic inhibition in the SCN Fulltext Access 26 Pages 2018
The association between inflammatory markers (iNOS, HO-1, IL-33, MIP-1β) and depression with and without posttraumatic stress disorder Fulltext Access 26 Pages 2018
Nesfatin-1 ameliorates testicular injury and supports gonadal function in rats induced with testis torsion Fulltext Access 26 Pages 2018
Involvement of α-methylene-γ- and δ-lactones in the suppression of multidrug resistance in MCF-7 cells Fulltext Access 26 Pages 2018
Children's contrast sensitivity function in relation to organophosphate insecticide prenatal exposure in the mother-child PELAGIE cohort Fulltext Access 27 Pages 2018
Neuroprotective action of 4-Hydroxyisophthalic acid against paraquat-induced motor impairment involves amelioration of mitochondrial damage and neurodegeneration in Drosophila Fulltext Access 27 Pages 2018
Immunofluorescence/fluorescence assessment of brain-derived neurotrophic factor, c-Fos activation, and apoptosis in the brain of zebrafish (Danio rerio) larvae exposed to glufosinate Fulltext Access 27 Pages 2018
Precision medicine approach: Empagliflozin for diabetic cardiomyopathy in mice with aldehyde dehydrogenase (ALDH) 2â¯*â¯2 mutation, a specific genetic mutation in millions of East Asians Fulltext Access 27 Pages 2018
Skin nociceptive block with pramoxine delivery by subcutaneous injection in rats Fulltext Access 27 Pages 2018
Developmental exposure to low concentrations of two brominated flame retardants, BDE-47 and BDE-99, causes life-long behavioral alterations in zebrafish Fulltext Access 27 Pages 2018
Reduction in voluntary food intake, but not fasting, stimulates hypothalamic gonadotropin-inhibitory hormone precursor mRNA expression in chicks under heat stress Fulltext Access 27 Pages 2018
Farnesoid X receptor agonist obeticholic acid inhibits renal inflammation and oxidative stress during lipopolysaccharide-induced acute kidney injury Fulltext Access 27 Pages 2018
Sesquiterpene lactone from Artemisia argyi induces gastric carcinoma cell apoptosis via activating NADPH oxidase/reactive oxygen species/mitochondrial pathway Fulltext Access 27 Pages 2018
Suramin is a novel competitive antagonist selective to α1β2γ2 GABAA over Ï1 GABAC receptors Fulltext Access 27 Pages 2018
Median preoptic nucleus excitatory neurotransmitters in the maintenance of hypertensive state Fulltext Access 27 Pages 2018
Induction of beige adipocytes by naturally occurring β3-adrenoceptor agonist p-synephrine Fulltext Access 27 Pages 2018
Opioid and α2 adrenergic mechanisms are activated by GABA agonists in the lateral parabrachial nucleus to induce sodium intake Fulltext Access 27 Pages 2018
The impact of pericytes on the brain and approaches for their morphological analysis Fulltext Access 27 Pages 2018
Methodology for controlled administration of smoked synthetic cannabinoids JWH-018 and JWH-073 Fulltext Access 27 Pages 2018
Candesartan, angiotensin II type 1 receptor blocker is able to relieve age-related cognitive impairment Fulltext Access 27 Pages 2018
Mitigative role of garlic and vitamin E against cytotoxic, genotoxic, and apoptotic effects of lead acetate and mercury chloride on WI-38 cells Fulltext Access 27 Pages 2018
Identification and characterization of molluscan caveolin-1 ortholog from Haliotis discus discus: Possible involvement in embryogenesis and host defense mechanism against pathogenic stress Fulltext Access 27 Pages 2018
Multi-targeting effects of a new synthetic molecule (JM-20) in experimental models of cerebral ischemia Fulltext Access 27 Pages 2018
Icariside II, a PDE5 inhibitor from Epimedium brevicornum, promotes neuron-like pheochromocytoma PC12 cell proliferation via activating NO/cGMP/PKG pathway Fulltext Access 27 Pages 2018
The potential mechanism for Hydroxysafflor yellow A attenuating blood-brain barrier dysfunction via tight junction signaling pathways excavated by an integrated serial affinity chromatography and shotgun proteomics analysis approach Fulltext Access 27 Pages 2018
Overexpression of miR-219 promotes differentiation of human induced pluripotent stem cells into pre-oligodendrocyte Fulltext Access 27 Pages 2018
Oxidative stress and DNA damage after cerebral ischemia: Potential therapeutic targets to repair the genome and improve stroke recovery Fulltext Access 27 Pages 2018
Latent consequences of early-life lead (Pb) exposure and the future: Addressing the Pb crisis Fulltext Access 27 Pages 2018
Pharmacological rescue of mutated Kv3.1 ion-channel linked to progressive myoclonus epilepsies Fulltext Access 27 Pages 2018
Protective effect of propofol on ischemia-reperfusion injury detected by HPLC-MS/MS targeted metabolic profiling Fulltext Access 27 Pages 2018
Foenumoside B isolated from Lysimachia foenum-graecum extract suppresses LPS-induced inflammatory response via NF-κB/AP-1 inactivation in murine macrophages and in endotoxin-induced shock model Fulltext Access 27 Pages 2018
A novel pharmacodynamic model in rats for preventing vascular dementia from maintaining neurovascular coupling sensitivity Fulltext Access 27 Pages 2018
Autophagy is a major mechanism for the dual effects of curcumin on renal cell carcinoma cells Fulltext Access 27 Pages 2018
The potential role of glucokinase activator SHP289-04 in anti-diabetes and hepatic protection Fulltext Access 27 Pages 2018
Etizolam attenuates the reduction in cutaneous temperature induced in mice by exposure to synthetic predator odor Fulltext Access 27 Pages 2018
Alpha-asarone attenuates depression-like behavior in nicotine-withdrawn mice: Evidence for the modulation of hippocampal pCREB levels during nicotine-withdrawal Fulltext Access 27 Pages 2018
Antidiabetic and antiobesity effects of SGLT2 inhibitor ipragliflozin in type 2 diabetic mice fed sugar solution Fulltext Access 27 Pages 2018
Prolonged-access to cocaine induces distinct Homer2 DNA methylation, hydroxymethylation, and transcriptional profiles in the dorsomedial prefrontal cortex of Male Sprague-Dawley rats Fulltext Access 28 Pages 2018
A synthetic snake-venom-based tripeptide (Glu-Val-Trp) protects PC12 cells from MPP+ toxicity by activating the NGF-signaling pathway Fulltext Access 28 Pages 2018
Invasive fungi-derived defensins kill drug-resistant bacterial pathogens Fulltext Access 28 Pages 2018
Age-dependent expression pattern in the mammalian brain of a novel, small peptide encoded in the 22q11.2 deletion syndrome region Fulltext Access 28 Pages 2018
Tissue specific expression and in-silico characterization of a putative cysteine synthase gene from Lathyrus sativus L. Fulltext Access 28 Pages 2018
Chronic treatment with the phytocannabinoid Cannabidivarin (CBDV) rescues behavioural alterations and brain atrophy in a mouse model of Rett syndrome Fulltext Access 28 Pages 2018
Modulation of appetitive motivation by prefrontal cortical mu-opioid receptors is dependent upon local dopamine D1 receptor signaling Fulltext Access 28 Pages 2018
A SNAP-25 cleaving chimera of botulinum neurotoxin /A and /E prevents TNF뱉induced elevation of the activities of native TRP channels on early postnatal rat dorsal root ganglion neurons Fulltext Access 28 Pages 2018
Striatal GluN2B involved in motor skill learning and stimulus-response learning Fulltext Access 28 Pages 2018
Endogenous glutamate within the prelimbic and infralimbic cortices regulates the incubation of cocaine-seeking in rats Fulltext Access 28 Pages 2018