Neuroprotective effects of cordycepin inhibit Aβ-induced apoptosis in hippocampal neurons Fulltext Access 30 Pages 2018
Environmental neurotoxicant manganese regulates exosome-mediated extracellular miRNAs in cell culture model of Parkinson's disease: Relevance to α-synuclein misfolding in metal neurotoxicity Fulltext Access 30 Pages 2018
Brain derived neurotrophic factor (BDNF), its tyrosine kinase receptor B (TrkB) and nicotine Fulltext Access 30 Pages 2018
Hsp90 Co-chaperone p23 contributes to dopaminergic mitochondrial stress via stabilization of PHD2: Implications for Parkinson's disease Fulltext Access 30 Pages 2018
Protective effects of curcumin on acrolein-induced neurotoxicity in HT22 mouse hippocampal cells Fulltext Access 30 Pages 2018
Agathisflavone, a flavonoid derived from Poincianella pyramidalis (Tul.), enhances neuronal population and protects against glutamate excitotoxicity Fulltext Access 30 Pages 2018
Anti-angiogenic and anti-inflammatory effects of long-circulating liposomes co-encapsulating curcumin and doxorubicin on C26 murine colon cancer cells Fulltext Access 30 Pages 2018
Hemin blunts the depressant effect of chronic nicotine on reflex tachycardia via activation of central NOS/PI3K pathway in female rats Fulltext Access 30 Pages 2018
Prolonged therapy with antidepressants increases hippocampal level of kynurenic acid and expression of Kat1 and Kat2 genes Fulltext Access 30 Pages 2018
Isoliquiritigenin attenuates glutamate-induced mitochondrial fission via calcineurin-mediated Drp1 dephosphorylation in HT22 hippocampal neuron cells Fulltext Access 30 Pages 2018
Physcion 8-O-β-glucopyranoside exhibits anti-leukemic activity through targeting sphingolipid rheostat Fulltext Access 30 Pages 2018
Enhanced incentive motivation in obesity-prone rats is mediated by NAc core CP-AMPARs Fulltext Access 30 Pages 2018
Huntingtin protein: A new option for fixing the Huntington's disease countdown clock Fulltext Access 30 Pages 2018
Inhibition of activated factor X by rivaroxaban attenuates neointima formation after wire-mediated vascular injury Fulltext Access 31 Pages 2018
Combined iron chelator and T-type calcium channel blocker exerts greater efficacy on cardioprotection than monotherapy in iron-overload thalassemic mice Fulltext Access 31 Pages 2018
Characterization of a novel selective factor Xa inhibitor, DJT06001, which reduces thrombus formation with low risk of bleeding Fulltext Access 31 Pages 2018
Ginsenoside Rg1 protects rat bone marrow mesenchymal stem cells against ischemia induced apoptosis through miR-494-3p and ROCK-1 Fulltext Access 31 Pages 2018
(E)-2-Methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol attenuates PMA-induced inflammatory responses in human monocytic cells through PKCδ/JNK/AP-1 pathways Fulltext Access 31 Pages 2018
Two novel dual GLP-1/GIP receptor agonists are neuroprotective in the MPTP mouse model of Parkinson's disease Fulltext Access 31 Pages 2018
κ-opioid receptor activation protects against myocardial ischemia-reperfusion injury via AMPK/Akt/eNOS signaling activation Fulltext Access 31 Pages 2018
Effects of amphipathic profile regularization on structural order and interaction with membrane models of two highly cationic branched peptides with β-sheet propensity Fulltext Access 31 Pages 2018
Separating the agony from ecstasy: R(-)-3,4-methylenedioxymethamphetamine has prosocial and therapeutic-like effects without signs of neurotoxicity in mice Fulltext Access 31 Pages 2018
Decarboxylation of Ang-(1-7) to Ala1-Ang-(1-7) leads to significant changes in pharmacodynamics Fulltext Access 31 Pages 2018
7-Fluoro-1,3-diphenylisoquinoline reverses motor and non-motor symptoms induced by MPTP in mice: Role of striatal neuroinflammation Fulltext Access 31 Pages 2018
Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats Fulltext Access 31 Pages 2018
Hyperactivity and memory/learning deficits evoked by developmental exposure to nicotine and/or ethanol are mitigated by cAMP and cGMP signaling cascades activation Fulltext Access 31 Pages 2018
Spinal injection of newly identified cerebellin-1 and cerebellin-2 peptides induce mechanical hypersensitivity in mice Fulltext Access 31 Pages 2018
Connexin43, but not connexin30, contributes to adult neurogenesis in the dentate gyrus Fulltext Access 31 Pages 2018
Neurodegeneration in the olfactory bulb and olfactory deficits in the Ccdc66 -/- mouse model for retinal degeneration Fulltext Access 31 Pages 2018
Trigonelline inhibits caspase 3 to protect β cells apoptosis in streptozotocin-induced type 1 diabetic mice Fulltext Access 31 Pages 2018
Inhibition of Rho kinase by GSK 269962 reverses both corticosterone-induced detrusor overactivity and depression-like behaviour in rats Fulltext Access 31 Pages 2018
Modality selective roles of pro-nociceptive spinal 5-HT2A and 5-HT3 receptors in normal and neuropathic states Fulltext Access 31 Pages 2018
Implementation of fluorescence anisotropy-based assay for the characterization of ligand binding to dopamine D1 receptors Fulltext Access 31 Pages 2018
miR-381 induces sensitivity of breast cancer cells to doxorubicin by inactivation of MAPK signaling via FYN Fulltext Access 31 Pages 2018
Inhibition of NRF2 signaling and increased reactive oxygen species during embryogenesis in a rat model of retinoic acid-induced neural tube defects Fulltext Access 31 Pages 2018
Insulin downregulates C3 gene expression in human HepG2 cells through activation of PPARγ Fulltext Access 31 Pages 2018
Nicotinic acetylcholine receptor (nAChR) mediated dopamine release in larval Drosophila melanogaster Fulltext Access 31 Pages 2018
Changes in the concentrations of inflammatory and oxidative status biomediators (MIP-1 α, PMN elastase, MDA, and IL-12) in depressed patients with and without posttraumatic stress disorder Fulltext Access 31 Pages 2018
Characterization of a new, inducible transgenic mouse model with GFP expression in melanocytes and their precursors Fulltext Access 31 Pages 2018
Effect of acetaminophen on osteoblastic differentiation and migration of MC3T3-E1 cells Fulltext Access 31 Pages 2018
Kaempferol modulates Angiopoietin-like protein 2 expression to lessen the mastitis in mice Fulltext Access 31 Pages 2018
A new tridecapeptide with an octaarginine vector has analgesic therapeutic potential and prevents morphine-induced tolerance Fulltext Access 31 Pages 2018
GLP-1 signaling and alcohol-mediated behaviors; preclinical and clinical evidence Fulltext Access 31 Pages 2018
Aβ-oligomer uptake and the resulting inflammatory response in adult human astrocytes are precluded by an anti-Aβ single chain variable fragment in combination with an apoE mimetic peptide Fulltext Access 31 Pages 2018
Regulation of the ARE-binding proteins, TTP (tristetraprolin) and HuR (human antigen R), in inflammatory response in astrocytes Fulltext Access 31 Pages 2018
Developmental changes of GABA immunoreactivity in cortico-thalamic networks of an absence seizure model Fulltext Access 31 Pages 2018
The reduction in glutamate release is predictive of cognitive and emotional alterations that are corrected by the positive modulator of AMPA receptors S 47445 in perinatal stressed rats Fulltext Access 31 Pages 2018
Beta estradiol and norepinephrine treatment of differentiated SH-SY5Y cells enhances tau phosphorylation at (Ser396) and (Ser262) via AMPK but not mTOR signaling pathway Fulltext Access 32 Pages 2018
Perturbations in the p53/miR-34a/SIRT1 pathway in the R6/2 Huntington's disease model Fulltext Access 32 Pages 2018
Deletion of the endogenous TrkB.T1 receptor isoform restores the number of hippocampal CA1 parvalbumin-positive neurons and rescues long-term potentiation in pre-symptomatic mSOD1(G93A) ALS mice Fulltext Access 32 Pages 2018
Evaluating the broad-spectrum efficacy of the acetylcholinesterase oximes reactivators MMB4 DMS, HLö-7 DMS, and 2-PAM Cl against phorate oxon, sarin, and VX in the Hartley guinea pig Fulltext Access 32 Pages 2018
Prenatal bisphenol A (BPA) exposure alters the transcriptome of the neonate rat amygdala in a sex-specific manner: a CLARITY-BPA consortium study Fulltext Access 32 Pages 2018
Facilitated AMPAR endocytosis causally contributes to the maternal sleep deprivation-induced impairments of synaptic plasticity and cognition in the offspring rats Fulltext Access 32 Pages 2018
Sodium P-aminosalicylic acid inhibits sub-chronic manganese-induced neuroinflammation in rats by modulating MAPK and COX-2 Fulltext Access 32 Pages 2018
Mitochondrial Ca2+-activated K+ channels and their role in cell life and death pathways Fulltext Access 32 Pages 2018
GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose Fulltext Access 32 Pages 2018
Systemic administration of scAAV9-IGF1 extends survival in SOD1G93A ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway Fulltext Access 32 Pages 2018
Dysfunction of SERCA pumps as novel mechanism of methylglyoxal cytotoxicity Fulltext Access 32 Pages 2018
The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome Fulltext Access 32 Pages 2018
Modulatory role of the intra-accumbal CB1 receptor in protein level of the c-fos and pCREB/CREB ratio in the nucleus accumbens and ventral tegmental area in extinction and morphine seeking in the rats Fulltext Access 32 Pages 2018
P-gp is involved in the intestinal absorption and biliary excretion of afatinib in vitro and in rats Fulltext Access 32 Pages 2018
Autophagy induced by cardamonin is associated with mTORC1 inhibition in SKOV3 cells Fulltext Access 32 Pages 2018
TRPV1 modulates morphine self-administration via activation of the CaMKII-CREB pathway in the nucleus accumbens Fulltext Access 32 Pages 2018
Oxytocin is present in islets and plays a role in beta-cell function and survival Fulltext Access 32 Pages 2018
Protective effects of antioxidin-RL from Odorrana livida against ultraviolet B-irradiated skin photoaging Fulltext Access 32 Pages 2018
Role of orexin-1 receptors in the dorsal hippocampus (CA1 region) in expression and extinction of the morphine-induced conditioned place preference in the rats Fulltext Access 32 Pages 2018
Moderate treadmill exercise ameliorates amyloid-β-induced learning and memory impairment, possibly via increasing AMPK activity and up-regulation of the PGC-1α/FNDC5/BDNF pathway Fulltext Access 32 Pages 2018
Remifentanil preconditioning confers cardioprotection via c-Jun NH2-terminal kinases and extracellular signal regulated kinases pathways in ex-vivo failing rat heart Fulltext Access 32 Pages 2018
Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons Fulltext Access 32 Pages 2018
Selective HCN1 block as a strategy to control oxaliplatin-induced neuropathy Fulltext Access 32 Pages 2018
Neuroinflammation produced by heavy alcohol intake is due to loops of interactions between Toll-like 4 and TNF receptors, peroxisome proliferator-activated receptors and the central melanocortin system: A novel hypothesis and new therapeutic avenues Fulltext Access 32 Pages 2018
Lateral septum stimulation disinhibits dopaminergic neurons in the antero-ventral region of the ventral tegmental area: Role of GABA-A alpha 1 receptors Fulltext Access 32 Pages 2018
Perinatal fluoxetine prevents the effect of pre-gestational maternal stress on 5-HT in the PFC, but maternal stress has enduring effects on mPFC synaptic structure in offspring Fulltext Access 32 Pages 2018
Depolarizing, inhibitory GABA type A receptor activity regulates GABAergic synapse plasticity via ERK and BDNF signaling Fulltext Access 32 Pages 2018
Methylene blue activates the PMCA activity and cross-interacts with amyloid β-peptide, blocking Aβ-mediated PMCA inhibition Fulltext Access 32 Pages 2018
Profiling of orthosteric and allosteric group-III metabotropic glutamate receptor ligands on various G protein-coupled receptors with Tag-lite® assays Fulltext Access 32 Pages 2018
Inhibition of peptidylarginine deiminase alleviates LPS-induced pulmonary dysfunction and improves survival in a mouse model of lethal endotoxemia Fulltext Access 32 Pages 2018
Functional characterization of α7 nicotinic acetylcholine and NMDA receptor signaling in SH-SY5Y neuroblastoma cells in an ERK phosphorylation assay Fulltext Access 32 Pages 2018
6,7,4â²-Trihydroxyisoflavone, a major metabolite of daidzein, improves learning and memory via the cholinergic system and the p-CREB/BDNF signaling pathway in mice Fulltext Access 32 Pages 2018
Evaluation of the effects of RP5063, a novel, multimodal, serotonin receptor modulator, as single-agent therapy and co-administrated with sildenafil, bosentan, and treprostinil in a monocrotaline-induced pulmonary arterial hypertension rat model Fulltext Access 32 Pages 2018
Can crosstalk between DOR and PARP reduce oxidative stress mediated neurodegeneration? Fulltext Access 32 Pages 2018
Effect of sirolimus on liver cirrhosis and hepatic encephalopathy of common bile duct-ligated rats Fulltext Access 32 Pages 2018
Anti-IL-23 receptor monoclonal antibody prevents CD4+ T cell-mediated colitis in association with decreased systemic Th1 and Th17 responses Fulltext Access 32 Pages 2018
Lariciresinol induces apoptosis in HepG2 cells via mitochondrial-mediated apoptosis pathway Fulltext Access 32 Pages 2018
Pharmacological modulation of AMPA receptor phosphorylation by dopamine and muscarinic receptor agents in the rat medial prefrontal cortex Fulltext Access 32 Pages 2018
Assessments of cellular melatonin receptor signaling pathways: β-arrestin recruitment, receptor internalization, and impedance variations Fulltext Access 32 Pages 2018
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Fulltext Access 33 Pages 2018
Anti-allergic and anti-inflammatory effects of the Bcl-2 inhibitor ABT-737 on experimental allergic rhinitis models Fulltext Access 33 Pages 2018
Preventive effects of astragaloside IV and its active sapogenin cycloastragenol on cardiac fibrosis of mice by inhibiting the NLRP3 inflammasome Fulltext Access 33 Pages 2018
Fentanyl and naloxone effects on glutamate and GABA release rates from anterior hypothalamus in freely moving rats Fulltext Access 33 Pages 2018
Changes in synaptic AMPA receptor concentration and composition in chronic temporal lobe epilepsy Fulltext Access 33 Pages 2018
The small heat shock proteins, especially HspB4 and HspB5 are promising protectants in neurodegenerative diseases Fulltext Access 33 Pages 2018
Activation of M2 muscarinic acetylcholine receptors by a hybrid agonist enhances cytotoxic effects in GB7 glioblastoma cancer stem cells Fulltext Access 33 Pages 2018
Gestational stress in mouse dams negatively affects gestation and postpartum hippocampal BDNF and P11 protein levels Fulltext Access 33 Pages 2018