Antinociceptive effects of the endogenous cannabinoid peptide agonist VD-hemopressin(β) in mice Fulltext Access 33 Pages 2018
Aβ pathology downregulates brain mGluR5 density in a mouse model of Alzheimer Fulltext Access 33 Pages 2018
Brainstem GLP-1 signalling contributes to cancer anorexia-cachexia syndrome in the rat Fulltext Access 33 Pages 2018
Role of mGlu7 receptor in morphine rewarding effects is uncovered by a novel orthosteric agonist Fulltext Access 33 Pages 2018
Usefulness of pharmacokinetic/efficacy analysis of an investigational kisspeptin analog, TAK-448, in quantitatively evaluating anti-tumor growth effect in the rat VCaP androgen-sensitive prostate cancer model Fulltext Access 33 Pages 2018
miRNA-185 serves as a prognostic factor and suppresses migration and invasion through Wnt1 in colon cancer Fulltext Access 33 Pages 2018
Xanthoceraside attenuates amyloid β peptide1-42-induced memory impairments by reducing neuroinflammatory responses in mice Fulltext Access 33 Pages 2018
Role of K+ channels in regulating spontaneous activity in the muscularis mucosae of guinea pig bladder Fulltext Access 33 Pages 2018
Puerarin acts on the skeletal muscle to improve insulin sensitivity in diabetic rats involving μ-opioid receptor Fulltext Access 33 Pages 2018
Appetite-associated responses to central neuropeptide Y injection in quail Fulltext Access 33 Pages 2018
Aβ oligomer eliminating compounds interfere successfully with pEAβ(3-42) induced motor neurodegenerative phenotype in transgenic mice Fulltext Access 33 Pages 2018
Synthesis of breast cancer targeting conjugate of temporin-SHa analog and its effect on pro- and anti-apoptotic protein expression in MCF-7 cells Fulltext Access 33 Pages 2018
Reactivation of denervated Schwann cells by neurons induced from bone marrow-derived mesenchymal stem cells Fulltext Access 33 Pages 2018
Increased ethanol drinking in “humanized” mice expressing the mu opioid receptor A118G polymorphism are mediated through sex-specific mechanisms Fulltext Access 33 Pages 2018
Potential role of the ecto-5â²-nucleotidase in morphine-induced uridine release and neurobehavioral changes Fulltext Access 33 Pages 2018
Diagnostic value of chemerin in lower gastrointestinal diseases-a review Fulltext Access 33 Pages 2018
Yeast red pigment modifies cloned human α-synuclein pathogenesis in Parkinson disease models in Saccharomyces cerevisiae and Drosophila melanogaster Fulltext Access 33 Pages 2018
Re-examining the potential of targeting ABHD6 in multiple sclerosis: Efficacy of systemic and peripherally restricted inhibitors in experimental autoimmune encephalomyelitis Fulltext Access 33 Pages 2018
Conditioned gaping produced by high dose Î9-tetrahydracannabinol: Dysregulation of the hypothalamic endocannabinoid system Fulltext Access 33 Pages 2018
Fluoxetine or Sox2 reactivate proliferation-defective stem and progenitor cells of the adult and aged dentate gyrus Fulltext Access 33 Pages 2018
Pluchea lanceolata protects hippocampal neurons from endothelin-1 induced ischemic injury to ameliorate cognitive deficits Fulltext Access 33 Pages 2018
LncRNA SNHG1 promotes α-synuclein aggregation and toxicity by targeting miR-15b-5p to activate SIAH1 in human neuroblastoma SH-SY5Y cells Fulltext Access 33 Pages 2018
Distribution of the pig gastrin-releasing peptide receptor and the effect of GRP on porcine Leydig cells Fulltext Access 33 Pages 2018
Melatonin suppresses eosinophils and Th17 cells in hamsters treated with a combination of human liver fluke infection and a chemical carcinogen Fulltext Access 33 Pages 2018
Protective effects of stigmasterol against ketamineâinduced psychotic symptoms: Possible behavioral, biochemical and histopathological changes in mice Fulltext Access 33 Pages 2018
Modulation of P2X7 purinergic receptor activity by extracellular Zn2+ in cultured mouse hippocampal astroglia Fulltext Access 33 Pages 2018
Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control Fulltext Access 33 Pages 2018
Inhibition of mitochondrial permeability transition pore opening contributes to cannabinoid type 1 receptor agonist ACEA-induced neuroprotection Fulltext Access 33 Pages 2018
Rac1 modulates G-protein-coupled receptor-induced bronchial smooth muscle contraction Fulltext Access 34 Pages 2018
Blockade of NMDA receptors blocks the acquisition of cocaine conditioned approach in rats Fulltext Access 34 Pages 2018
Hydrogen sulfide attenuates homocysteine-induced neurotoxicity by preventing mitochondrial dysfunctions and oxidative damage: In vitro and in vivo studies Fulltext Access 34 Pages 2018
Methamphetamine toxicity-induced calcineurin activation, nuclear translocation of nuclear factor of activated T-cells and elevation of cyclooxygenase 2 levels are averted by calpastatin overexpression in neuroblastoma SH-SY5Y cells Fulltext Access 34 Pages 2018
Association of MRI T1 relaxation time with neuropsychological test performance in manganese- exposed welders Fulltext Access 34 Pages 2018
The spatial and developmental expression of mouse Vwa8 (von Willebrand domain-containing protein 8) Fulltext Access 34 Pages 2018
Chrysophanol inhibits endoplasmic reticulum stress in cerebral ischemia and reperfusion mice Fulltext Access 34 Pages 2018
Age-dependent alterations in expression and co-localization of Pax6 and Ras-GAP in brain of aging mice Fulltext Access 34 Pages 2018
MicroRNA-499a decelerates glioma cell proliferation while accelerating apoptosis through the suppression of Notch1 and the MAPK signaling pathway Fulltext Access 34 Pages 2018
Pistacia lentiscus oil attenuates memory dysfunction and decreases levels of biomarkers of oxidative stress induced by lipopolysaccharide in rats Fulltext Access 34 Pages 2018
In vitro antiglycating effect and in vivo neuroprotective activity of Trigonelline in d-galactose induced cognitive impairment Fulltext Access 34 Pages 2018
Blockade of platelet-activating factor receptor attenuates abnormal behaviors induced by phencyclidine in mice through down-regulation of NF-κB Fulltext Access 34 Pages 2018
Oxytocin release via activation of TRPM2 and CD38 in the hypothalamus during hyperthermia in mice: Implication for autism spectrum disorder Fulltext Access 34 Pages 2018
Assessment of the possible roles of SB-269970 versus ketanserin on carbon tetrachloride-induced liver fibrosis in rats: Oxidative stress/TGF-β1-induced HSCs activation pathway Fulltext Access 34 Pages 2018
Deletion of Kir6.2/SUR1 potassium channels rescues diminishing of DA neurons via decreasing iron accumulation in PD Fulltext Access 34 Pages 2018
Drug-drug interaction potential of antitumor acridine agent C-1748: The substrate of UDP-glucuronosyltransferases 2B7, 2B17 and the inhibitor of 1A9 and 2B7 Fulltext Access 34 Pages 2018
Systemic L-buthionine-S-R-sulfoximine administration modulates glutathione homeostasis via NGF/TrkA and mTOR signaling in the cerebellum Fulltext Access 34 Pages 2018
Elabela, a newly discovered APJ ligand: Similarities and differences with Apelin Fulltext Access 34 Pages 2018
Nucleus accumbens GLT-1a overexpression reduces glutamate efflux during reinstatement of cocaine-seeking but is not sufficient to attenuate reinstatement Fulltext Access 34 Pages 2018
Resveratrol attenuates pro-inflammatory cytokines and activation of JAK1-STAT3 in BTBR T+ Itpr3tf/J autistic mice Fulltext Access 34 Pages 2018
Endogenous dopamine and endocannabinoid signaling mediate cocaine-induced reversal of AMPAR synaptic potentiation in the nucleus accumbens shell Fulltext Access 34 Pages 2018
Serotonergic mechanisms involved in antidepressant-like responses evoked by GLT-1 blockade in rat infralimbic cortex Fulltext Access 34 Pages 2018
Acute effects of vortioxetine and duloxetine on resting-state functional connectivity in the awake rat Fulltext Access 34 Pages 2018
GSH depletion, mitochondrial membrane breakdown, caspase-3/7 activation and DNA fragmentation in U87MG glioblastoma cells: New insight into the mechanism of cytotoxicity induced by fluoroquinolones Fulltext Access 34 Pages 2018
Understanding antidepressant discontinuation syndrome (ADS) through preclinical experimental models Fulltext Access 34 Pages 2018
PAC-1 and its derivative WF-210 Inhibit Angiogenesis by inhibiting VEGF/VEGFR pathway Fulltext Access 34 Pages 2018
Selective downregulation of vesicular glutamate transporter2 in ventral posterolateral nucleus of thalamus attenuates neuropathic mechanical allodynia in mice Fulltext Access 34 Pages 2018
Regulation of P2X7 receptor function of neural progenitor cells in the hippocampal subgranular zone by neuronal activity in the dentate gyrus Fulltext Access 34 Pages 2018
A novel PPARα/γ agonist, propane-2-sulfonic acid octadec-9-enyl-amide, ameliorates insulin resistance and gluconeogenesis in vivo and vitro Fulltext Access 34 Pages 2018
Protective effects of α-mangostin against acetaminophen-induced acute liver injury in mice Fulltext Access 34 Pages 2018
GABA dramatically improves glucose tolerance in streptozotocin-induced diabetic rats fed with high-fat diet Fulltext Access 34 Pages 2018
The Role of Mitochondria in Methamphetamine-induced inhibitory effects on osteogenesis of Mesenchymal Stem Cells Fulltext Access 34 Pages 2018
Chrysin reverses the depressive-like behavior induced by hypothyroidism in female mice by regulating hippocampal serotonin and dopamine Fulltext Access 34 Pages 2018
Chronic ethanol consumption increases vascular oxidative stress and the mortality induced by sub-lethal sepsis: Potential role of iNOS Fulltext Access 34 Pages 2018
Nicorandil and theophylline can protect experimental rats against complete Freund's adjuvant-induced rheumatoid arthritis through modulation of JAK/STAT/RANKL signaling pathway Fulltext Access 34 Pages 2018
Thymol alleviates lipopolysaccharide-stimulated inflammatory response via downregulation of RhoA-mediated NF-κB signalling pathway in human peritoneal mesothelial cells Fulltext Access 35 Pages 2018
Identification and functional characterization of zebrafish K2P17.1 (TASK-4, TALK-2) two-pore-domain K+ channels Fulltext Access 35 Pages 2018
Antitumor effects of seleno-β-lactoglobulin (Se-β-Lg) against human gastric cancer MGC-803 cells Fulltext Access 35 Pages 2018
Rutin restricts hydrogen peroxide-induced alterations by up-regulating the redox-system: An in vitro, in vivo and in silico study Fulltext Access 35 Pages 2018
Protection by tyrosine kinase inhibitor, tyrphostin AG126, through the suppression of IL-17A, RORγt, and T-bet signaling, in the BTBR mouse model of autism Fulltext Access 35 Pages 2018
Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M4 PAM VU0467154 Fulltext Access 35 Pages 2018
Melatonin inhibits rotenone-induced SH-SY5Y cell death via the downregulation of Dynamin-Related Protein 1 expression Fulltext Access 35 Pages 2018
Stimulation of accumbal GABAB receptors inhibits delta1- and delta2-opioid receptor-mediated dopamine efflux in the nucleus accumbens of freely moving rats Fulltext Access 35 Pages 2018
Reduced cortical serotonin 5-HT2A receptor binding and glutamate activity in high compulsive drinker rats Fulltext Access 35 Pages 2018
Maternal voluntary exercise ameliorates learning deficit in rat pups exposed, in utero, to valproic acid; role of BDNF and VEGF and their receptors Fulltext Access 35 Pages 2018
Exendin-4 attenuates neuronal death via GLP-1R/PI3K/Akt pathway in early brain injury after subarachnoid hemorrhage in rats Fulltext Access 35 Pages 2018
Hypoglycemic mechanism of a novel proteoglycan, extracted from Ganoderma lucidum, in hepatocytes Fulltext Access 35 Pages 2018
Osteopontin attenuates inflammation via JAK2/STAT1 pathway in hyperglycemic rats after intracerebral hemorrhage Fulltext Access 35 Pages 2018
Antioxidant N-acetylcysteine inhibits maladaptive myocyte autophagy in pressure overload induced cardiac remodeling in rats Fulltext Access 35 Pages 2018
GLP-1 receptor agonists stimulate ANGPTL8 production through the PI3K/Akt pathway in a GLP-1 receptor-dependent manner Fulltext Access 35 Pages 2018
Blockage of endoplasmic reticulum stress attenuates nilotinib-induced cardiotoxicity by inhibition of the Akt-GSK3β-Nox4 signaling Fulltext Access 35 Pages 2018
PLGA nanoparticles loaded with beta-lactoglobulin-derived peptides modulate mucosal immunity and may facilitate cow's milk allergy prevention Fulltext Access 35 Pages 2018
DA5-CH, a novel GLP-1/GIP dual agonist, effectively ameliorates the cognitive impairments and pathology in the APP/PS1 mouse model of Alzheimer's disease Fulltext Access 35 Pages 2018
Protective effect of S-nitrosoglutathione administration against hyperglycemia induced disruption of blood brain barrier is mediated by modulation of tight junction proteins and cell adhesion molecules Fulltext Access 35 Pages 2018
A cAMP analog attenuates beta-amyloid (1-42)-induced mitochondrial dysfunction and spatial learning and memory deficits Fulltext Access 35 Pages 2018
Clonidine preconditioning improved cerebral ischemia-induced learning and memory deficits in rats via ERK1/2-CREB/ NF-κB-NR2B pathway Fulltext Access 35 Pages 2018
3,7-Bis(2-hydroxyethyl)icaritin, a potent inhibitor of phosphodiesterase-5, prevents monocrotaline-induced pulmonary arterial hypertension via NO/cGMP activation in rats Fulltext Access 35 Pages 2018
Motoneuron degeneration in the trigeminal motor nucleus innervating the masseter muscle in Dystonia musculorum mice Fulltext Access 35 Pages 2018
Abediterol (LAS100977), an inhaled long-acting β2-adrenoceptor agonist, has a fast association rate and long residence time at receptor Fulltext Access 35 Pages 2018
ATP-sensitive potassium-channel inhibitor glibenclamide attenuates HPA axis hyperactivity, depression- and anxiety-related symptoms in a rat model of Alzheimer's disease Fulltext Access 35 Pages 2018
Local energy on demand: Are 'spontaneous' astrocytic Ca2+-microdomains the regulatory unit for astrocyte-neuron metabolic cooperation? Fulltext Access 35 Pages 2018
Barbiturates enhance itch-associated scratching in atopic dermatitis mice: A possible clue to understanding nocturnal pruritus in atopic dermatitis Fulltext Access 35 Pages 2018
Ginkgolide K promotes angiogenesis in a middle cerebral artery occlusion mouse model via activating JAK2/STAT3 pathway Fulltext Access 35 Pages 2018
PQBP1, an intrinsically disordered/denatured protein at the crossroad of intellectual disability and neurodegenerative diseases Fulltext Access 35 Pages 2018
Mice deficient in AKAP13 (BRX) develop compulsive-like behavior and increased body weight Fulltext Access 36 Pages 2018
Integration of 1H NMR- and UPLC-Q-TOF/MS-based plasma metabonomics study to identify diffuse axonal injury biomarkers in rat Fulltext Access 36 Pages 2018