Disulfide-bond formation in the H+-pyrophosphatase of Streptomyces coelicolor and its implications for redox control and enzyme structure Fulltext Access 7 Pages 2005
Analysis of glycoside hydrolase family 98: Catalytic machinery, mechanism and a novel putative carbohydrate binding module Fulltext Access 7 Pages 2005
Characterization of the DNA-binding site in the ferric uptake regulator protein from Escherichia coli by UV crosslinking and mass spectrometry Fulltext Access 7 Pages 2005
An archaeal SET domain protein exhibits distinct lysine methyltransferase activity towards DNA-associated protein MC1-α Fulltext Access 7 Pages 2005
Alternative splicing regulates the transcriptional activity of Drosophila heat shock transcription factor in response to heat/cold stress Fulltext Access 7 Pages 2005
Nitrite as the major source of nitric oxide production by Arabidopsis thaliana in response to Pseudomonas syringae Fulltext Access 7 Pages 2005
Identification of a villin-related tobacco protein as a novel cross-reactive plant allergen Fulltext Access 7 Pages 2005
Mutations in the NDUFS4 gene of mitochondrial complex I alter stability of the splice variants Fulltext Access 7 Pages 2005
Ceramide-1-phosphate promotes cell survival through activation of the phosphatidylinositol 3-kinase/protein kinase B pathway Fulltext Access 7 Pages 2005
Sp1 elements in SULT2B1b promoter and 5′-untranslated region of mRNA: Sp1/Sp2 induction and augmentation by histone deacetylase inhibition Fulltext Access 7 Pages 2005
Role of the PDK1–PKB–GSK3 pathway in regulating glycogen synthase and glucose uptake in the heart Fulltext Access 7 Pages 2005
Inhibition of matrix metalloproteinase-9 by interferons and TGF-β1 through distinct signalings accounts for reduced monocyte invasiveness Fulltext Access 7 Pages 2005
Purification and functional reconstitution of the human Wilson copper ATPase, ATP7B Fulltext Access 7 Pages 2005
Cry11Aa toxin from Bacillus thuringiensis binds its receptor in Aedes aegypti mosquito larvae through loop α-8 of domain II Fulltext Access 7 Pages 2005
ALK5 and Smad4 are involved in TGF-β1-induced pulmonary endothelial permeability Fulltext Access 7 Pages 2005
PACAP protects neuronal differentiated PC12 cells against the neurotoxicity induced by a mitochondrial complex I inhibitor, rotenone Fulltext Access 7 Pages 2005
The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment Fulltext Access 7 Pages 2005
Interleukin-4 downregulates TNFα-induced IL-8 production in keratinocytes Fulltext Access 7 Pages 2005
Suppressors of RNA silencing encoded by plant viruses and their role in viral infections Fulltext Access 7 Pages 2005
Novel type aquaporin SIPs are mainly localized to the ER membrane and show cell-specific expression in Arabidopsis thaliana Fulltext Access 7 Pages 2005
Comparison of uniformity of dose response of double layer radiochromic films (MD-55-2) measured at 5 institutions Fulltext Access 7 Pages 2005
Comparison of rectal dose-volume constraints for IMRT prostate treatment planning Fulltext Access 7 Pages 2005
A comparison of two image fusion techniques in ct-on-rails localization of radiation delivery Fulltext Access 7 Pages 2005
Nucleotide binding to the homodimeric MJ0796 protein: A computational study of a prokaryotic ABC transporter NBD dimer Fulltext Access 7 Pages 2005
ASF/SF2 and SC35 regulate the glutamate receptor subunit 2 alternative flip/flop splicing Fulltext Access 7 Pages 2005
Functional replacement of Drosophila Btk29A with human Btk in male genital development and survival Fulltext Access 7 Pages 2005
Regulation of lipopolysaccharide-induced inflammatory response by glutathione S-transferase P1 in RAW264.7 cells Fulltext Access 7 Pages 2005
ZD1839 (Gefitinib, ‘Iressa’), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma Fulltext Access 7 Pages 2005
Grifolin, a potential antitumor natural product from the mushroom Albatrellus confluens, inhibits tumor cell growth by inducing apoptosis in vitro Fulltext Access 7 Pages 2005
Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase Fulltext Access 7 Pages 2005
A genome-wide analysis of sumoylation-related biological processes and functions in human nucleus Fulltext Access 7 Pages 2005
Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1 Fulltext Access 7 Pages 2005
Identification and characterization of rDJL, a novel member of the DnaJ protein family, in rat testis Fulltext Access 7 Pages 2005
The Saccharomyces cerevisiae Ca2+ channel Cch1pMid1p is essential for tolerance to cold stress and iron toxicity Fulltext Access 7 Pages 2005
Identification and analysis of Hic-5/ARA55 isoforms: Implications for integrin signaling and steroid hormone action Fulltext Access 7 Pages 2005
Single chain antibody against the common epitope of mutant p53 restores wild-type activity to mutant p53 protein Fulltext Access 7 Pages 2005
The effects of partial thiamin deficiency and oxidative stress (i.e., glyoxal and methylglyoxal) on the levels of α-oxoaldehyde plasma protein adducts in Fischer 344 rats Fulltext Access 7 Pages 2005
ADAM12-mediated focal adhesion formation is differently regulated by β1 and β3 integrins Fulltext Access 7 Pages 2005
The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase Fulltext Access 7 Pages 2005
Validating the use of database potentials in protein structure determination by NMR Fulltext Access 7 Pages 2005
Progesterone inhibits human breast cancer cell growth through transcriptional upregulation of the cyclin-dependent kinase inhibitor p27Kip1 gene Fulltext Access 7 Pages 2005
Selective activation of adrenergic β1 receptors induces heme oxygenase 1 production in RAW264.7 cells Fulltext Access 7 Pages 2005
A transposon-based activation-tagging population in Arabidopsis thaliana (TAMARA) and its application in the identification of dominant developmental and metabolic mutations Fulltext Access 7 Pages 2005
IRF-1 mediates upregulation of LMP7 by IFN-γ and concerted expression of immunosubunits of the proteasome Fulltext Access 7 Pages 2005
Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium Fulltext Access 7 Pages 2005
Exclusive paternal expression and novel alternatively spliced variants of ε-sarcoglycan mRNA in mouse brain Fulltext Access 7 Pages 2005
Changes in linkage pattern of glucan products induced by substitution of Lys residues in the dextransucrase Fulltext Access 7 Pages 2005
CO: A chemical ontology for identification of functional groups and semantic comparison of small molecules Fulltext Access 7 Pages 2005
Ubiquitin and ubiquitin-derived peptides as substrates for peptidylglycine α-amidating monooxygenase Fulltext Access 7 Pages 2005
Histidine inhibits oxidative stress- and TNF-α-induced interleukin-8 secretion in intestinal epithelial cells Fulltext Access 7 Pages 2005
Characterization of a poplar NIMA-related kinase PNek1 and its potential role in meristematic activity Fulltext Access 7 Pages 2005
Mutational analysis of the active center of plant fructosyltransferases: Festuca 1-SST and barley 6-SFT Fulltext Access 7 Pages 2005
The role of PKCα and RLIP76 in transport-mediated doxorubicin-resistance in lung cancer Fulltext Access 7 Pages 2005
Molecular mechanism of hypoxia-mediated hepatic gluconeogenesis by transcriptional regulation Fulltext Access 7 Pages 2005
The Drosophila type II receptor, Wishful thinking, binds BMP and myoglianin to activate multiple TGFβ family signaling pathways Fulltext Access 7 Pages 2005
Conformation-driven and semiquinone-gated proton-pump mechanism in the NADH-ubiquinone oxidoreductase (complex I) Fulltext Access 7 Pages 2005
Activation of c-Jun NH2-terminal kinase is required for gemcitabine’s cytotoxic effect in human lung cancer H1299 cells Fulltext Access 7 Pages 2005
Escherichia coli verotoxin 1 mediates apoptosis in human HCT116 colon cancer cells by inducing overexpression of the GADD family of genes and S phase arrest Fulltext Access 7 Pages 2005
Inhibition of the HERG K+ channel by the antifungal drug ketoconazole depends on channel gating and involves the S6 residue F656 Fulltext Access 7 Pages 2005
QSAR analysis of thiazole benzenesulfonamide substituted 3-pyridylethanolamines as β3-adrenergic receptor agonist Fulltext Access 7 Pages 2005
Hologram quantitative structure–activity relationships for a series of farnesoid X receptor activators Fulltext Access 7 Pages 2005
Carbonic anhydrase inhibitors: Novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX Fulltext Access 7 Pages 2005
Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines Fulltext Access 7 Pages 2005
Rapid rates of newly synthesized mitochondrial protein degradation are significantly affected by the generation of mitochondrial free radicals Fulltext Access 7 Pages 2005
Transgenic tobacco plants overexpressing glyoxalase enzymes resist an increase in methylglyoxal and maintain higher reduced glutathione levels under salinity stress Fulltext Access 7 Pages 2005
Nitric oxide induces tau hyperphosphorylation via glycogen synthase kinase-3β activation Fulltext Access 7 Pages 2005
Synthesis of (di)nucleoside polyphosphates by the ubiquitin activating enzyme E1 Fulltext Access 7 Pages 2005
The “resurrection method” for modification of specific proteins in higher plants Fulltext Access 7 Pages 2005
Characterization of the dinuclear metal center of Pyrococcus furiosus prolidase by analysis of targeted mutants Fulltext Access 7 Pages 2005
The NK-lysin derived peptide NK-2 preferentially kills cancer cells with increased surface levels of negatively charged phosphatidylserine Fulltext Access 7 Pages 2005
Identification and characterization of a triacylglycerol lipase in Arabidopsis homologous to mammalian acid lipases Fulltext Access 7 Pages 2005
Differentiation of circulating endothelial progenitor cells to a cardiomyogenic phenotype depends on E-cadherin Fulltext Access 7 Pages 2005
Cloning, expression, characterisation and three-dimensional structure determination of Caenorhabditis elegans spermidine synthase Fulltext Access 7 Pages 2005
Structural and morphological characterization of hemozoin produced by Schistosoma mansoni and Rhodnius prolixus Fulltext Access 7 Pages 2005
Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure–activity relationships of the 7- and 5-, 6-, 8-positions Fulltext Access 7 Pages 2005
Sulfite facilitates LDL lipid oxidation by transition metal ions: A pro-oxidant in wine? Fulltext Access 7 Pages 2005
Topo IIα reporter mice reveal proliferative regions in the epidermis and small intestine Fulltext Access 7 Pages 2005
A major ozonation product of cholesterol, 3β-hydroxy-5-oxo-5,6-secocholestan-6-al, induces apoptosis in H9c2 cardiomyoblasts Fulltext Access 7 Pages 2005
Analysis of expression of growth factor receptors in replicatively and oxidatively senescent human fibroblasts Fulltext Access 7 Pages 2005
Plasma membrane and lysosomal localization of CB1 cannabinoid receptor are dependent on lipid rafts and regulated by anandamide in human breast cancer cells Fulltext Access 7 Pages 2005
Apical cell adhesion molecule, trophinin, localizes to the nuclear envelope Fulltext Access 7 Pages 2005
Regulation of divalent metal transporter expression in human intestinal epithelial cells following exposure to non-haem iron Fulltext Access 7 Pages 2005
ERK-dependent induction of TNFα expression by the environmental contaminant benzo(a)pyrene in primary human macrophages Fulltext Access 7 Pages 2005
The inhibitory mechanism of curcumin and its derivative against β-catenin/Tcf signaling Fulltext Access 7 Pages 2005
Induction of ornithine decarboxylase in T/C-28a2 chondrocytes by lysophosphatidic acid: Signaling pathway and inhibition of cell proliferation Fulltext Access 7 Pages 2005