Identification of a UDP-Gal: GlcNAc-R galactosyltransferase activity in Escherichia coli VW187 Fulltext Access 7 Pages 2005
Unified Markov thermodynamics based on stochastic forms to classify drugs considering molecular structure, partition system, and biological species: Fulltext Access 7 Pages 2005
QSAR study on pKa vis-Ã -vis physiological activity of sulfonamides: a dominating role of surface tension (inverse steric parameter) Fulltext Access 7 Pages 2005
Amino-substituted heterocycles as isosteres of trans-cinnamides: design and synthesis of heterocyclic biaryl sulfides as potent antagonists of LFA-1/ICAM-1 binding Fulltext Access 7 Pages 2005
Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers Fulltext Access 7 Pages 2005
Novel β-(imidazol-4-yl)-β-amino acids: solid-phase synthesis and study of their inhibitory activity against geranylgeranyl protein transferase type I Fulltext Access 7 Pages 2005
Estrogen receptor ligands. Part 10: Chromanes: old scaffolds for new SERAMs Fulltext Access 7 Pages 2005
QSAR for anti-RNA-virus activity, synthesis, and assay of anti-RSV carbonucleosides given a unified representation of spectral moments, quadratic, and topologic indices Fulltext Access 7 Pages 2005
Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 3: Identification and biological activity of indanone containing mGlu2 receptor potentiators Fulltext Access 7 Pages 2005
Novel cyclopentane dicarboxamide sodium channel blockers as a potential treatment for chronic pain Fulltext Access 7 Pages 2005
QSAR studies on 1,2-dithiole-3-thiones: modeling of lipophilicity, quinone reductase specific activity, and production of growth hormone Fulltext Access 7 Pages 2005
Effects of positional and geometrical isomerism on the biological activity of some novel oxazolidinones Fulltext Access 7 Pages 2005
Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs? Fulltext Access 7 Pages 2005
Studies on synthesis and evaluation of quantitative structure-activity relationship of 5-[(3â²-chloro-4â²,4â²-disubstituted-2-oxoazetidinyl)(N-nitro)amino]-6-hydroxy-3-alkyl/aryl[1,3]azaphospholo[1,5-a]pyridin-1-yl-phosphorus dichlorides Fulltext Access 7 Pages 2005
Effect of new antioxidant cysteinyl-flavanol conjugates on skin cancer cells Fulltext Access 7 Pages 2005
The FAXWXXT motif in the carboxyl terminus of Vibrio mimicus metalloprotease is involved in binding to collagen Fulltext Access 7 Pages 2005
Origin, distribution and 3D-modeling of Gr-EXPB1, an expansin from the potato cyst nematode Globodera rostochiensis Fulltext Access 7 Pages 2005
Nitration and oligomerization of tau induced by peroxynitrite inhibit its microtubule-binding activity Fulltext Access 7 Pages 2005
Small interfering RNA inhibits SARS-CoV nucleocapsid gene expression in cultured cells and mouse muscles Fulltext Access 7 Pages 2005
The characterization of plasma membrane Ca2+-ATPase in rich sphingomyelin–cholesterol domains Fulltext Access 7 Pages 2005
PTEN expression in ovine granulosa cells increases during terminal follicular growth Fulltext Access 7 Pages 2005
Involvement of matrix metalloproteinase-9 in platelet-activating factor-induced angiogenesis Fulltext Access 7 Pages 2005
The biosynthesis of ascorbate protects isolated rat hepatocytes from cumene hydroperoxide-mediated oxidative stress Fulltext Access 7 Pages 2005
Overexpression of copper/zinc superoxide dismutase decreases ischemia-like astrocyte injury Fulltext Access 7 Pages 2005
Arginase-1 overexpression induces cationic amino acid transporter-1 in psoriasis Fulltext Access 7 Pages 2005
Elevation of superoxide dismutase increases acoustic trauma from noise exposure Fulltext Access 7 Pages 2005
Evidence for α-tocopherol regeneration reaction of green tea polyphenols in SDS micelles Fulltext Access 7 Pages 2005
Pulse radiolysis study of the interaction of retinoids with peroxyl radicals Fulltext Access 7 Pages 2005
Cadmium chloride-induced oxidative stress in skeletal muscle cells in vitro Fulltext Access 7 Pages 2005
Antioxidant enzyme activity is up-regulated after unilateral resistance exercise training in older adults Fulltext Access 7 Pages 2005
Radical mediators and mitogen-activated protein kinase signaling in oxygen-dependent radiosensitivity of human tumor cell lines Fulltext Access 7 Pages 2005
Human mitochondrial peroxiredoxin 5 protects from mitochondrial DNA damages induced by hydrogen peroxide Fulltext Access 7 Pages 2005
Osmium tetroxide, used in the treatment of arthritic joints, is a fast mimic of superoxide dismutase Fulltext Access 7 Pages 2005
Intracellular generation of reactive oxygen species by contracting skeletal muscle cells Fulltext Access 7 Pages 2005
β-Sitosterol modulates antioxidant enzyme response in RAW 264.7 macrophages Fulltext Access 7 Pages 2005
Optimization of selenium status by a single intraperitoneal injection of Se in Se-deficient rat: Possible application to burned patient treatment Fulltext Access 7 Pages 2005
Oxypurinol improves coronary and peripheral endothelial function in patients with coronary artery disease Fulltext Access 7 Pages 2005
Benzo[a]pyrene and its metabolites combined with ultraviolet A synergistically induce 8-hydroxy-2â²-deoxyguanosine via reactive oxygen species Fulltext Access 7 Pages 2005
5-Chloroindoloyl glycine amide inhibitors of glycogen phosphorylase: synthesis, in vitro, in vivo, and X-ray crystallographic characterization Fulltext Access 7 Pages 2005
QSAR study on the antibacterial activity of some sulfa drugs: building blockers of Mannich bases Fulltext Access 7 Pages 2005
cda1+, encoding chitin deacetylase is required for proper spore formation in Schizosaccharomyces pombe Fulltext Access 7 Pages 2005
Glucose deprivation mediates interaction between CTDK-I and Snf1 in Saccharomyces cerevisiae Fulltext Access 7 Pages 2005
The verprolin family of proteins: Regulators of cell morphogenesis and endocytosis Fulltext Access 7 Pages 2005
Understanding the enzymology of fibrinolysis and improving thrombolytic therapy Fulltext Access 7 Pages 2005
Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract Fulltext Access 7 Pages 2005
At the pulse of time: protein interactions determine the pace of circadian clocks Fulltext Access 7 Pages 2005
The regulation of proteasome degradation by multi-ubiquitin chain binding proteins Fulltext Access 7 Pages 2005
A crevice adjoining the ribosome tunnel: Hints for cotranslational folding Fulltext Access 7 Pages 2005
The Drosophila homologue of the dystrophin gene – Introns containing promoters are the major contributors to the large size of the gene Fulltext Access 7 Pages 2005
Purkinje-cell degeneration in prion protein-deficient mice is associated with a cerebellum-specific Doppel protein species signature Fulltext Access 7 Pages 2005
Long CGG-repeat tracts are toxic to human cells: Implications for carriers of Fragile X premutation alleles Fulltext Access 7 Pages 2005
Oligomerization and assembly of the matrix protein of Borna disease virus Fulltext Access 7 Pages 2005
Molecular basis of the allosteric mechanism of cAMP in the regulatory PKA subunit Fulltext Access 7 Pages 2005
Distribution profile of inositol 1,4,5-trisphosphate receptor isoforms in adrenal chromaffin cells Fulltext Access 7 Pages 2005
Transcriptional regulation of connective tissue growth factor by sphingosine 1-phosphate in rat cultured mesangial cells Fulltext Access 7 Pages 2005
Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium Fulltext Access 7 Pages 2005
Inhibitors of HCV NS5B polymerase. Part 2: Evaluation of the northern region of (2Z)-2-benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid Fulltext Access 7 Pages 2005
Synthesis and SAR of highly potent dual 5-HT1A and 5-HT1B antagonists as potential antidepressant drugs Fulltext Access 7 Pages 2005
A genome-wide expression profile and system-level integration of nuclear factor kappa B regulated genes reveals fundamental metabolic adaptations during cell growth and survival Fulltext Access 7 Pages 2005
The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs Fulltext Access 7 Pages 2005
Effect of EPS1 gene deletion in Saccharomyces cerevisiae on the secretion of foreign proteins which have disulfide bridges Fulltext Access 7 Pages 2005
Water and molecular chaperones act as weak links of protein folding networks: Energy landscape and punctuated equilibrium changes point towards a game theory of proteins Fulltext Access 7 Pages 2005
Adiponectin is synthesized and secreted by human and murine cardiomyocytes Fulltext Access 7 Pages 2005
Subcellular distribution of chromogranins A and B in bovine adrenal chromaffin cells Fulltext Access 7 Pages 2005
Microsomal triglyceride transfer protein expression in adipocytes: A new component in fat metabolism Fulltext Access 7 Pages 2005
Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in growth hormone treated animals Fulltext Access 7 Pages 2005
Peroxynitrite-mediated matrix metalloproteinase-2 activation in human hepatic stellate cells Fulltext Access 7 Pages 2005
Specific inhibition of HIV-1 replication by short hairpin RNAs targeting human cyclin T1 without inducing apoptosis Fulltext Access 7 Pages 2005
CysMap and CysJoin: Database and tools for protein disulphides localisation Fulltext Access 7 Pages 2005
Nitric oxide mediates anti-inflammatory action of extracorporeal shock waves Fulltext Access 7 Pages 2005
Identification of the novel evolutionary conserved obstructor multigene family in invertebrates Fulltext Access 7 Pages 2005
Identification of coumarin derivatives as a novel class of allosteric MEK1 inhibitors Fulltext Access 7 Pages 2005
ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes Fulltext Access 7 Pages 2005
The binding of mycolic acids to galectin-3: A novel interaction between a host soluble lectin and trafficking mycobacterial lipids? Fulltext Access 7 Pages 2005
Identification of multiple allosteric sites on the M1 muscarinic acetylcholine receptor Fulltext Access 7 Pages 2005
Epac1 regulates integrity of endothelial cell junctions through VE-cadherin Fulltext Access 7 Pages 2005
Hypertonic sodium chloride induction of cyclooxygenase-2 occurs independently of NF-κB and is inhibited by the glucocorticoid receptor in A549 cells Fulltext Access 7 Pages 2005
Role of sodium in mitochondrial membrane depolarization induced by P2X7 receptor activation in submandibular glands Fulltext Access 7 Pages 2005
Protonation state of Asp30 exerts crucial influence over surface loop rearrangements responsible for NO release in nitrophorin 4 Fulltext Access 7 Pages 2005
Structural basis for recognition of ubiquitinated cargo by Tom1-GAT domain Fulltext Access 7 Pages 2005
Phosphorylation of cold shock domain/Y-box proteins by ERK2 and GSK3β and repression of the human VEGF promoter Fulltext Access 7 Pages 2005