Design and evaluation of antibiotic releasing self- assembled scaffolds at room temperature using biodegradable polymer particles Fulltext Access 40 Pages 2017
Synthesis and pharmacological evaluation of benzamide derivatives as potent and selective sigma-1 protein ligands Fulltext Access 40 Pages 2017
Developing potential agents against atherosclerosis: Design, synthesis and pharmacological evaluation of novel dual inhibitors of oxidative stress and Squalene Synthase activity Fulltext Access 40 Pages 2017
Effect of surfactants and drug load on physico-mechanical and dissolution properties of nanocrystalline tadalafil-loaded oral films Fulltext Access 40 Pages 2017
Designing multi-targeted agents: An emerging anticancer drug discovery paradigm Fulltext Access 40 Pages 2017
Design and synthesis of bis(indolyl)ketohydrazide-hydrazones: Identification of potent and selective novel tubulin inhibitors Fulltext Access 40 Pages 2017
Effects of Coating Materials and Processing Conditions on Flow Enhancement of Cohesive Acetaminophen Powders by High-Shear Processing With Pharmaceutical Lubricants Fulltext Access 40 Pages 2017
How to identify and eliminate compounds with a risk of high clinical dose during the early phase of lead optimisation in drug discovery Fulltext Access 40 Pages 2017
Novel aryl piperazines for alleviation of 'andropause' associated prostatic disorders and depression Fulltext Access 40 Pages 2017
Investigation of itraconazole ternary amorphous solid dispersions based on povidone and Carbopol Fulltext Access 40 Pages 2017
Synthesis, stability and mechanistic studies of potent anticryptococcal hexapeptides Fulltext Access 40 Pages 2017
Synthesis and evaluation of naphthyl bearing 1,2,3-triazole analogs as antiplasmodial agents, cytotoxicity and docking studies Fulltext Access 40 Pages 2017
Discovery of novel diarylpyrazolylquinoline derivatives as potent anti-dengue virus agents Fulltext Access 40 Pages 2017
Development of novel double-decker microneedle patches for transcutaneous vaccine delivery Fulltext Access 40 Pages 2017
Development of a Novel Formulation That Improves Preclinical Bioavailability of Tenofovir Disoproxil Fumarate Fulltext Access 40 Pages 2017
Preformulation studies of ceftriaxone for pediatric non-parenteral administration as an alternative to existing injectable formulations Fulltext Access 41 Pages 2017
Effect of anti-diabetic drugs on bone metabolism: Evidence from preclinical and clinical studies Fulltext Access 41 Pages 2017
Design, synthesis and evaluation of novel 2-amino-3-(naphth-2-yl)propanoic acid derivatives as potent inhibitors of platelet aggregation Fulltext Access 41 Pages 2017
Identifying overarching excipient properties towards an in-depth understanding of process and product performance for continuous twin-screw wet granulation Fulltext Access 41 Pages 2017
A compressibility based model for predicting the tensile strength of directly compressed pharmaceutical powder mixtures Fulltext Access 41 Pages 2017
Effect of plasticizers on the physico-mechanical properties of pullulan based pharmaceutical oral films Fulltext Access 41 Pages 2017
Model-based precision dosing of sirolimus in pediatric patients with vascular anomalies Fulltext Access 41 Pages 2017
Synthesis and antibacterial activity of new symmetric polyoxygenated dibenzofurans Fulltext Access 41 Pages 2017
Development, characterization and in vitro evaluation of biodegradable rhein-loaded microparticles for treatment of osteoarthritis Fulltext Access 41 Pages 2017
Cell microencapsulation technology: Current vision of its therapeutic potential through the administration routes Fulltext Access 41 Pages 2017
Synthesis and bioevaluation of 1-phenyl-pyrazole-4-carboxylic acid derivatives as potent xanthine oxidoreductase inhibitors Fulltext Access 41 Pages 2017
Development of a Predictive Model for the Long-Term Stability Assessment of Drug-In-Adhesive Transdermal Films Using Polar Pressure-Sensitive Adhesives as Carrier/Matrix Fulltext Access 41 Pages 2017
The role of subcutaneous tissue stiffness on microneedle performance in a representative in vitro model of skin Fulltext Access 42 Pages 2017
The formation and physical stability of two-phase solid dispersion systems of indomethacin in supercooled molten mixtures with different matrix formers Fulltext Access 42 Pages 2017
Medicines for Pediatric Patients-Biopharmaceutical, Developmental, and Regulatory Considerations Fulltext Access 42 Pages 2017
Recent developments in small molecule therapies for renal cell carcinoma Fulltext Access 42 Pages 2017
An integrated approach towards the discovery of novel non-nucleoside Leishmania major pteridine reductase 1 inhibitors Fulltext Access 42 Pages 2017
Diphenylurea derivatives for combating methicillin- and vancomycin-resistant Staphylococcus aureus Fulltext Access 42 Pages 2017
Ferritin nanocage with intrinsically disordered proteins and affibody: A platform for tumor targeting with extended pharmacokinetics Fulltext Access 42 Pages 2017
Design, synthesis, and biological evaluation of optimized phthalazine derivatives as hedgehog signaling pathway inhibitors Fulltext Access 42 Pages 2017
Sustained release of intravitreal flurbiprofen from a novel drug-in-liposome-in-hydrogel formulation Fulltext Access 42 Pages 2017
Analysis of polymorphic contamination in meloxicam raw materials and its effects on the physicochemical quality of drug product Fulltext Access 42 Pages 2017
Synthesis and biological evaluation of salinomycin triazole analogues as anticancer agents Fulltext Access 42 Pages 2017
Harnessing the cross-talk between tumor cells and tumor-associated macrophages with a nano-drug for modulation of glioblastoma immune microenvironment Fulltext Access 43 Pages 2017
Involvement of Proton-Coupled Organic Cation Antiporter in Varenicline Transport at Blood-Brain Barrier of Rats and in Human Brain Capillary Endothelial Cells Fulltext Access 43 Pages 2017
The Use of Hemoglobin Vesicles for Delivering Medicinal Gas for the Treatment of Intractable Disorders Fulltext Access 43 Pages 2017
Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanisms Fulltext Access 43 Pages 2017
Development of fine solid-crystal suspension with enhanced solubility, stability, and aerosolization performance for dry powder inhalation Fulltext Access 43 Pages 2017
Low-Molecular-Weight Heparin-Coated and Montelukast-Filled Inhalable Particles: A Dual-Drug Delivery System for Combination Therapy in Asthma Fulltext Access 43 Pages 2017
Controlled release from aspirin based linear biodegradable poly(anhydride esters) for anti-inflammatory activity Fulltext Access 43 Pages 2017
Chitosan-zein nano-in-microparticles capable of mediating in vivo transgene expression following oral delivery Fulltext Access 43 Pages 2017
Design, synthesis, and biological evaluation of structurally modified isoindolinone and quinazolinone derivatives as hedgehog pathway inhibitors Fulltext Access 44 Pages 2017
Simvastatin-loaded nanostructured lipid carriers attenuate the atherogenic risk of erythrocytes in hyperlipidemic rats Fulltext Access 44 Pages 2017
Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease Fulltext Access 44 Pages 2017
A Formulation Development Approach to Identify and Select Stable Ultra-High-Concentration Monoclonal Antibody Formulations With Reduced Viscosities Fulltext Access 44 Pages 2017
Effect of Grinding on the Solid-State Stability and Particle Dissolution of Acyclovir Polymorphs Fulltext Access 44 Pages 2017
Biopharmaceutical characterization of praziquantel cocrystals and cyclodextrin complexes prepared by grinding Fulltext Access 44 Pages 2017
Improving blend content uniformity via dry particle coating of micronized drug powders Fulltext Access 44 Pages 2017
Macro-Raman spectroscopy for bulk composition and homogeneity analysis of multi-component pharmaceutical powders Fulltext Access 44 Pages 2017
Involvement of Organic Cation Transporters in the Kinetics of Trimethylamine N-oxide Fulltext Access 45 Pages 2017
Inhibitors of protein arginine deiminases and their efficacy in animal models of multiple sclerosis Fulltext Access 45 Pages 2017
Exploration of flexible phenylpropylurea scaffold as novel cardiac myosin activators for the treatment of systolic heart failure Fulltext Access 45 Pages 2017
Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase Fulltext Access 45 Pages 2017
Synthesis and biological evaluation of chemokine receptor ligands with 2-benzazepine scaffold Fulltext Access 45 Pages 2017
Near-infrared monitoring of roller compacted ribbon density: Investigating sources of variation contributing to noisy spectral data Fulltext Access 45 Pages 2017
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease Fulltext Access 45 Pages 2017
Graphene- gold based nanocomposites applications in cancer diseases; Efficient detection and therapeutic tools Fulltext Access 45 Pages 2017
Enzyme inhibitory activities an insight into the structure-Activity relationship of biscoumarin derivatives Fulltext Access 46 Pages 2017
Effect of Polysorbate 20 and Polysorbate 80 on the Higher-Order Structure of a Monoclonal Antibody and Its Fab and Fc Fragments Probed Using 2D Nuclear Magnetic Resonance Spectroscopy Fulltext Access 46 Pages 2017
Applications of parallel synthetic lead hopping and pharmacophore-based virtual screening in the discovery of efficient glycine receptor potentiators Fulltext Access 46 Pages 2017
Towards the antioxidant therapy in Osteoarthritis: Contribution of nanotechnology Fulltext Access 46 Pages 2017
Solid state characterization of azelnidipine-oxalic acid co-crystal and co-amorphous complexes: The effect of different azelnidipine polymorphs Fulltext Access 46 Pages 2017
The Constraints, Construction, and Verification of a Strain-Specific Physiologically Based Pharmacokinetic Rat Model Fulltext Access 46 Pages 2017
A novel glucagon-like peptide-1/glucagon receptor dual agonist exhibits weight-lowering and diabetes-protective effects Fulltext Access 46 Pages 2017
A diffusing wave spectroscopy study of pharmaceutical emulsions for physical stability assessment Fulltext Access 46 Pages 2017
An approach for chemical stability during melt extrusion of a drug substance with a high melting point Fulltext Access 46 Pages 2017
Development of resveratrol-curcumin hybrids as potential therapeutic agents for inflammatory lung diseases Fulltext Access 46 Pages 2017
Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics Fulltext Access 46 Pages 2017
Targeted delivery of morin, a dietary bioflavanol encapsulated mannosylated liposomes to the macrophages of adjuvant-induced arthritis rats inhibits inflammatory immune response and osteoclastogenesis Fulltext Access 47 Pages 2017
Influence of substituent heteroatoms on the cytoprotective properties of pyrimidinol antioxidants Fulltext Access 47 Pages 2017
Extracellular vesicles in food: Experimental evidence of their secretion in grape fruits Fulltext Access 47 Pages 2017
Towards antibody-drug conjugates and prodrug strategies with extracellular stimuli-responsive drug delivery in the tumor microenvironment for cancer therapy Fulltext Access 47 Pages 2017
Pharmaceutical counselling about different types of tablet-splitting methods based on the results of weighing tests and mechanical development of splitting devices Fulltext Access 47 Pages 2017
New molecular targets for functionalized nanosized drug delivery systems in personalized therapy for hepatocellular carcinoma Fulltext Access 47 Pages 2017
Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea Fulltext Access 47 Pages 2017
Novel flavonolignan hybrid antioxidants: From enzymatic preparation to molecular rationalization Fulltext Access 47 Pages 2017
Design, selective alkylation and X-ray crystal structure determination of dihydro-indolyl-1,2,4-triazole-3-thione and its 3-benzylsulfanyl analogue as potent anticancer agents Fulltext Access 47 Pages 2017
Synthesis, anti-varicella-zoster virus and anti-cytomegalovirus activity of quinazoline-2,4-diones containing isoxazolidine and phosphonate substructures Fulltext Access 47 Pages 2017