A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies Fulltext Access 18 Pages 2007
Synthesis and c-Src inhibitory activity of imidazo[1,5-a]pyrazine derivatives as an agent for treatment of acute ischemic stroke Fulltext Access 18 Pages 2007
Design, synthesis, and biological evaluation of substituted-N-(thieno[2,3-b]pyridin-3-yl)-guanidines, N-(1H-pyrrolo[2,3-b]pyridin-3-yl)-guanidines, and N-(1H-indol-3-yl)-guanidines Fulltext Access 18 Pages 2007
Evaluation of bEnd5 cell line as an in vitro model for the blood-brain barrier under normal and hypoxic/aglycemic conditions Fulltext Access 18 Pages 2007
Computational neural network analysis of the affinity of lobeline and tetrabenazine analogs for the vesicular monoamine transporter-2 Fulltext Access 18 Pages 2007
Adaptive neuro-fuzzy inference system (ANFIS): A new approach to predictive modeling in QSAR applications: A study of neuro-fuzzy modeling of PCP-based NMDA receptor antagonists Fulltext Access 18 Pages 2007
Prodrug-based design, synthesis, and biological evaluation of N-benzenesulfonylpiperidine derivatives as novel, orally active factor Xa inhibitors Fulltext Access 18 Pages 2007
A drug release study from hydroxypropylmethylcellulose (HPMC) matrices using QSPR modeling Fulltext Access 18 Pages 2007
Chiral discrimination and enantioselective analysis of drugs: An overview Fulltext Access 18 Pages 2007
Evaluation of tunable diode laser absorption spectroscopy for inâprocess water vapor mass flux measurements during freeze drying Fulltext Access 18 Pages 2007
Selective angiotensin II AT2 receptor agonists devoid of the imidazole ring system Fulltext Access 18 Pages 2007
Physical Characterization of Component Particles Included in Dry Powder Inhalers. II. Dynamic Characteristics Fulltext Access 18 Pages 2007
Inhibitors of type III secretion in Yersinia: Design, synthesis and multivariate QSAR of 2-arylsulfonylamino-benzanilides Fulltext Access 18 Pages 2007
Structure–activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2 Fulltext Access 18 Pages 2007
Developing the role of pharmacists as members of community mental health teams: Perspectives of pharmacists and mental health professionals Fulltext Access 18 Pages 2007
Mental health case conferences in primary care: Content and treatment decision making Fulltext Access 18 Pages 2007
The impact of increasing workloads and role expansion on female community pharmacists in the United Kingdom Fulltext Access 18 Pages 2007
Formulation, lyophilization and solid-state properties of a pegylated protein Fulltext Access 18 Pages 2007
Physiologically Based Pharmacokinetic (PBPK) Modeling of Disposition of Epiroprim in Humans Fulltext Access 18 Pages 2007
Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder Fulltext Access 18 Pages 2007
Lysosomal Sequestration of Amine-Containing Drugs: Analysis and Therapeutic Implications Fulltext Access 18 Pages 2007
Toxicogenomics of non-viral drug delivery systems for RNAi: Potential impact on siRNA-mediated gene silencing activity and specificity Fulltext Access 19 Pages 2007
Circadian variation of blood pressure: The basis for the chronotherapy of hypertension Fulltext Access 19 Pages 2007
Pharmaceutical applications of confocal laser scanning microscopy: The physical characterisation of pharmaceutical systems Fulltext Access 19 Pages 2007
In vivo animal models for drug delivery across the lung mucosal barrier Fulltext Access 19 Pages 2007
Chronobiology of hemostasis and inferences for the chronotherapy of coagulation disorders and thrombosis prevention Fulltext Access 19 Pages 2007
Review of prescription medications in home-based older adults with stroke: A pilot study Fulltext Access 19 Pages 2007
The Role of the Cyclic Imide in Alternate Degradation Pathways for AsparagineâContaining Peptides and Proteins Fulltext Access 19 Pages 2007
Qualitative in situ analysis of multiple solidâstate forms using spectroscopy and partial least squares discriminant modeling Fulltext Access 19 Pages 2007
The effect of DTC advertisement content on belief tenacity: A study of appeals and argument types Fulltext Access 19 Pages 2007
Inhibition of secretory phospholipase A2. 2-Synthesis and structure–activity relationship studies of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one (PMS1062) derivatives specific for group II enzyme Fulltext Access 19 Pages 2007
An expeditious synthesis of tamoxifen, a representative SERM (selective estrogen receptor modulator), via the three-component coupling reaction among aromatic aldehyde, cinnamyltrimethylsilane, and β-chlorophenetole Fulltext Access 19 Pages 2007
Hybrid molecules between distamycin A and active moieties of antitumor agents Fulltext Access 19 Pages 2007
Phenylethyl-substituted pyrimido[2,1-f]purinediones and related compounds: Structure–activity relationships as adenosine A1 and A2A receptor ligands Fulltext Access 19 Pages 2007
Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: Use of cyclopentane and cyclopentene P2-motifs Fulltext Access 19 Pages 2007
Synthesis and evaluation of new 6-hydroximinosteroid analogs as cytotoxic agents Fulltext Access 19 Pages 2007
Novel 1-(azacyclyl)-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines as 5-HT6 agonists and antagonists Fulltext Access 19 Pages 2007
Synthesis of novel antitumoural analogues of dysidiolide from ent-halimic acid Fulltext Access 19 Pages 2007
The impact of an automated dose-dispensing scheme on user compliance, medication understanding, and medication stockpiles Fulltext Access 20 Pages 2007
Mitotic drug targets and the development of novel anti-mitotic anticancer drugs Fulltext Access 20 Pages 2007
Overcoming resistance to molecularly targeted anticancer therapies: Rational drug combinations based on EGFR and MAPK inhibition for solid tumours and haematologic malignancies Fulltext Access 20 Pages 2007
A nonlinear feedback model capturing different patterns of tolerance and rebound Fulltext Access 20 Pages 2007
The relationship between water vapor absorption and desorption by phospholipids and bilayer phase transitions Fulltext Access 20 Pages 2007
Substituted thiophene-anthranilamides as potent inhibitors of human factor Xa Fulltext Access 20 Pages 2007
Evaluation of the porosity, the tortuosity, and the hindrance factor for the transdermal delivery of hydrophilic permeants in the context of the aqueous pore pathway hypothesis using dualâradiolabeled permeability experiments Fulltext Access 20 Pages 2007
Physical Characterization of Component Particles Included in Dry Powder Inhalers. I. Strategy Review and Static Characteristics Fulltext Access 20 Pages 2007
Development of a high throughput equilibrium solubility assay using miniaturized shakeâflask method in early drug discovery Fulltext Access 20 Pages 2007
Design and synthesis of new potent dipeptidyl peptidase IV inhibitors with enhanced ex vivo duration Fulltext Access 20 Pages 2007
Design and synthesis of piperidine farnesyltransferase inhibitors with reduced glucuronidation potential Fulltext Access 20 Pages 2007
Synthesis and evaluation of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic and sedative properties Fulltext Access 20 Pages 2007
Design, synthesis and biological evaluation of new oligopyrrole carboxamides linked with tricyclic DNA-intercalators as potential DNA ligands or topoisomerase inhibitors Fulltext Access 20 Pages 2007
4-Amino-5-aryl-6-arylethynylpyrimidines: Structure–activity relationships of non-nucleoside adenosine kinase inhibitors Fulltext Access 20 Pages 2007
Implications of circadian clocks for the rhythmic delivery of cancer therapeutics Fulltext Access 21 Pages 2007
Nanofiber technology: Designing the next generation of tissue engineering scaffolds Fulltext Access 21 Pages 2007
Design and synthesis of manganese porphyrins with tailored lipophilicity: Investigation of redox properties and superoxide dismutase activity Fulltext Access 21 Pages 2007
Functional electrospun nanofibrous scaffolds for biomedical applications Fulltext Access 21 Pages 2007
Synthesis and HMG CoA reductase inhibition of 4-thiophenyl quinolines as potential hypocholesterolemic agents Fulltext Access 21 Pages 2007
Advances in the development of new therapeutic agents targeting the NS3-4A serine protease or the NS5B RNA-dependent RNA polymerase of the hepatitis C virus Fulltext Access 21 Pages 2007
TOMOCOMD-CARDD descriptors-based virtual screening of tyrosinase inhibitors: Evaluation of different classification model combinations using bond-based linear indices Fulltext Access 21 Pages 2007
Therapeutic potential of AIF-mediated caspase-independent programmed cell death Fulltext Access 21 Pages 2007
Matrices and scaffolds for delivery of bioactive molecules in bone and cartilage tissue engineering Fulltext Access 21 Pages 2007
Design and synthesis of long-acting inhibitors of dipeptidyl peptidase IV Fulltext Access 21 Pages 2007
Analysis, Interpretation, and Extrapolation of Dermal Permeation Data Using Diffusion-Based Mathematical Models Fulltext Access 22 Pages 2007
Disaccharide analogs as probes for glycosyltransferases in Mycobacterium tuberculosis Fulltext Access 22 Pages 2007
Correlations between Molecular Mobility and Chemical Stability During Storage of Amorphous Pharmaceuticals Fulltext Access 22 Pages 2007
Synthesis, biological activity, and SAR of antimycobacterial 2- and 8-substituted 6-(2-furyl)-9-(p-methoxybenzyl)purines Fulltext Access 22 Pages 2007
Structure–activity relationships of 3,4-dihydro-1H-quinazolin-2-one derivatives as potential CDK5 inhibitors Fulltext Access 22 Pages 2007
Antimicrobial and cytotoxic activity of agelasine and agelasimine analogs Fulltext Access 22 Pages 2007
Improved quantitative structure–activity relationship models to predict antioxidant activity of flavonoids in chemical, enzymatic, and cellular systems Fulltext Access 22 Pages 2007
A new class of anti-thrombosis hexahydropyrazino-[1′,2′:1,6]pyrido-[3,4-b]-indole-1,4-dions: Design, synthesis, log K determination, and QSAR analysis Fulltext Access 22 Pages 2007
High throughput solubility measurement in drug discovery and development Fulltext Access 22 Pages 2007
Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+-activated K+ channel (SKCa) Fulltext Access 23 Pages 2007
Pharmacists' and patients' roles in the pharmacist-patient relationship: Are pharmacists and patients reading from the same relationship script? Fulltext Access 23 Pages 2007
Evaluating telephone follow-up of a mail survey of community pharmacies Fulltext Access 23 Pages 2007
Machine learning approaches for predicting compounds that interact with therapeutic and ADMET related proteins Fulltext Access 23 Pages 2007
Visiting the ER: The endoplasmic reticulum as a target for therapeutics in traffic related diseases Fulltext Access 23 Pages 2007
Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective αvβ3 inhibitor: Design, synthesis, and optimization Fulltext Access 23 Pages 2007
New polyamine-sensitive inhibitors of the NMDA receptor: Syntheses and pharmacological evaluation Fulltext Access 23 Pages 2007