Discovery of potent, selective, and orally bioavailable inhibitors of interleukin-1 receptor-associate kinase-4 Fulltext Access 5 Pages 2015
An oxidative coupling product of luteolin with cysteine ester and its enhanced inhibitory activity for xanthine oxidase Fulltext Access 5 Pages 2015
Four new ginsenosides from red ginseng with inhibitory activity on melanogenesis in melanoma cells Fulltext Access 5 Pages 2015
Fluorophore-tagged pharmacophores for antitumor cytotoxicity: Modified chiral lipidic dialkynylcarbinols for cell imaging Fulltext Access 5 Pages 2015
Performance evaluation of structure based and ligand based virtual screening methods on ten selected anti-cancer targets Fulltext Access 5 Pages 2015
Fungal metabolite ophiobolin A as a promising anti-glioma agent: In vivo evaluation, structure-activity relationship and unique pyrrolylation of primary amines Fulltext Access 5 Pages 2015
The biological characteristics of a novel camptothecin-artesunate conjugate Fulltext Access 5 Pages 2015
The synthesis of sulforaphane analogues and their protection effect against cisplatin induced cytotoxicity in kidney cells Fulltext Access 5 Pages 2015
Further studies on anti-invasive chemotypes: An excursion from chalcones to curcuminoids Fulltext Access 5 Pages 2015
Transporter-mediated tissue targeting of therapeutic molecules in drug discovery Fulltext Access 5 Pages 2015
Initial optimization and series evolution of diaminopyrimidine inhibitors of interleukin-1 receptor associated kinase 4 Fulltext Access 5 Pages 2015
Inhibitory kinetics of novel 2,3-dihydro-1H-inden-1-one chalcone-like derivatives on mushroom tyrosinase Fulltext Access 5 Pages 2015
Design and synthesis of 1,1-disubstituted-1-silacycloalkane-based compound libraries Fulltext Access 5 Pages 2015
Synthesis and bioactivity of a Goralatide analog with antileukemic activity Fulltext Access 5 Pages 2015
Lipocarbazole, an efficient lipid peroxidation inhibitor anchored in the membrane Fulltext Access 5 Pages 2015
Synthesis and hybridization property of a boat-shaped pyranosyl nucleic acid containing an exocyclic methylene group in the sugar moiety Fulltext Access 5 Pages 2015
Development of a model for robust and exploratory analysis of the rodent brief-access taste aversion data Fulltext Access 5 Pages 2015
Laser-induced breakdown detection of temperature-ramp generated aggregates of therapeutic monoclonal antibody Fulltext Access 5 Pages 2015
Design, synthesis, and evaluation of new endomorphin analogs with enhanced central antinociception after peripheral administration Fulltext Access 5 Pages 2015
Amphiphilic drugs as surfactants to fabricate excipient-free stable nanodispersions of hydrophobic drugs for cancer chemotherapy Fulltext Access 5 Pages 2015
Synthesis, structure-activity relationship and biological evaluation of novel nitrogen mustard sophoridinic acid derivatives as potential anticancer agents Fulltext Access 5 Pages 2015
Structure-activity relationship studies of the lipophilic tail region of sphingosine kinase 2 inhibitors Fulltext Access 5 Pages 2015
Discovery of highly potent, lung-localized epithelial sodium channel inhibitors Fulltext Access 5 Pages 2015
Identification and optimisation of a series of tetrahydrobenzotriazoles as metabotropic glutamate receptor 5-selective positive allosteric modulators that improve performance in a preclinical model of cognition Fulltext Access 5 Pages 2015
Structure-activity-relationship of amide and sulfonamide analogs of omarigliptin Fulltext Access 5 Pages 2015
Charge-switching amino acids-based cationic lipids for efficient gene delivery Fulltext Access 5 Pages 2015
Selective oxidation of 5-hydroxymethylcytosine with micelle incarcerated oxidants to determine it at single base resolution Fulltext Access 5 Pages 2015
Design and synthesis of new series of coumarin-aminopyran derivatives possessing potential anti-depressant-like activity Fulltext Access 5 Pages 2015
Synthesis and biological evaluation of novel marine-derived indole-based 1,2,4-oxadiazoles derivatives as multifunctional neuroprotective agents Fulltext Access 5 Pages 2015
Identification of a new isomer from a reversible isomerization of ceftriaxone in aqueous solution Fulltext Access 5 Pages 2015
Design and synthesis of aloe-emodin derivatives as potent anti-tyrosinase, antibacterial and anti-inflammatory agents Fulltext Access 5 Pages 2015
Constituents of the seeds of Cassia tora with inhibitory activity on soluble expoxide hydrolease Fulltext Access 5 Pages 2015
Synthesis of heterocycle-attached methylidenebenzenesulfonohydrazones as antifungal agents Fulltext Access 5 Pages 2015
Discovery of novel oxazepine and diazepine carboxamides as two new classes of heat shock protein 90 inhibitors Fulltext Access 5 Pages 2015
Synthesis and biological evaluation of aryl isoxazole derivatives as metabotropic glutamate receptor 1 antagonists: A potential treatment for neuropathic pain Fulltext Access 5 Pages 2015
A novel molecule with notable activity against multi-drug resistant tuberculosis Fulltext Access 5 Pages 2015
Design and synthesis of novel 2-(indol-5-yl)thiazole derivatives as xanthine oxidase inhibitors Fulltext Access 5 Pages 2015
Metabolic glycoengineering sensitizes drug-resistant pancreatic cancer cells to tyrosine kinase inhibitors erlotinib and gefitinib Fulltext Access 5 Pages 2015
Synthesis and biological evaluation of pyrazolylthiazole carboxylic acids as potent anti-inflammatory-antimicrobial agents Fulltext Access 5 Pages 2015
Identification and purification of target protein using affinity resin bearing a photo-labile linker Fulltext Access 5 Pages 2015
Cyclopropyl-containing positive allosteric modulators of metabotropic glutamate receptor subtype 5 Fulltext Access 5 Pages 2015
The influence of electrical stimulation on dorsal raphe nucleus with different current intensities on morphine-induced conditioned place preference in male rats Fulltext Access 5 Pages 2015
Effect of a kynurenic acid analog on home-cage activity and body temperature in rats Fulltext Access 5 Pages 2015
Current approach for detection of sub-clinical left ventricular dysfunction associated with chemotherapy Fulltext Access 5 Pages 2015
Gastroprotective activity of ent-beyerene derivatives in mice: Effects on gastric secretion, endogenous prostaglandins and non-protein sulfhydryls Fulltext Access 5 Pages 2015
Synthesis and antifungal activity of ethers, alcohols, and iodohydrin derivatives of sclareol against phytopathogenic fungi in vitro Fulltext Access 5 Pages 2015
Thiophene and benzodioxole appended thiazolyl-pyrazoline compounds: Microwave assisted synthesis, antimicrobial and molecular docking studies Fulltext Access 5 Pages 2015
Synthesis of new thiazolylmethoxyphenyl pyrimidines and antihyperglycemic evaluation of the pyrimidines, analogues isoxazolines and pyrazolines Fulltext Access 5 Pages 2015
Synthesis and biological evaluation of novel pyrazoline derivatives as potent anti-inflammatory agents Fulltext Access 5 Pages 2015
Discovery of indolizines containing triazine moiety as new leads for the development of antitumoral agents targeting mitotic events Fulltext Access 5 Pages 2015
Synthesis and biological evaluation of levofloxacin core-based derivatives with potent antibacterial activity against resistant Gram-positive pathogens Fulltext Access 5 Pages 2015
Identification of amino acid appended acridines as potential leads to anti-cancer drugs Fulltext Access 5 Pages 2015
Antiviral activity and interaction mechanisms study of novel glucopyranoside derivatives Fulltext Access 5 Pages 2015
Cyclodextrin complexation highly enhances efficacy of arylsulfonylureido benzenesulfonamide carbonic anhydrase inhibitors as a topical antiglaucoma agents Fulltext Access 5 Pages 2015
Substrate-guided optimization of the syringolins yields potent proteasome inhibitors with activity against leukemia cell lines Fulltext Access 5 Pages 2015
Identification and screening of a tadalafil analogue found in adulterated herbal products Fulltext Access 5 Pages 2015
Microstructural analysis of the fast gelling freeze-dried sodium hyaluronate Fulltext Access 5 Pages 2015
Pharmacokinetics of propafenone hydrochloride sustained-release capsules in male beagle dogs Fulltext Access 5 Pages 2015
Determination of hydroxytyrosol and tyrosol by liquid chromatography for the quality control of cosmetic products based on olive extracts Fulltext Access 5 Pages 2015
Reprint of “Characterization of cyclodextrin containing nanofilters for removal of pharmaceutical residues” Fulltext Access 5 Pages 2015
Development and validation of a method for the analysis of hydroxyzine hydrochloride in extracellular solution used in in vitro preclinical safety studies Fulltext Access 5 Pages 2015
Application of capillary electrophoresis-frontal analysis for comparative evaluation of the binding interaction of captopril with human serum albumin in the absence and presence of hydrochlorothiazide Fulltext Access 5 Pages 2015
Development and characterization of a cationic lipid nanocarrier as non-viral vector for gene therapy Fulltext Access 5 Pages 2015
Modeling accelerated and decelerated drug release in terms of fractional release rate Fulltext Access 5 Pages 2015
A data mining approach to optimize pellets manufacturing process based on a decision tree algorithm Fulltext Access 5 Pages 2015
Novel thermosensitive in situ gel based on poloxamer for uterus delivery Fulltext Access 5 Pages 2015
Simultaneous determination of 3-chlorotyrosine and 3-nitrotyrosine in human plasma by direct analysis in real time–tandem mass spectrometry Fulltext Access 5 Pages 2015
Macrophage uptake of cylindrical microparticles investigated with correlative microscopy Fulltext Access 5 Pages 2015
Physical methods to quantify small antibiotic molecules uptake into Gram-negative bacteria Fulltext Access 5 Pages 2015
Antigen presenting cell-selective drug delivery by glycan-decorated nanocarriers Fulltext Access 5 Pages 2015
Involvement of nitridergic and opioidergic pathways in the antinociception of gabapentin in the orofacial formalin test in mice Fulltext Access 5 Pages 2015
The effect of ezetimibe-statin combination on steroid hormone production in men with coronary artery disease and low cholesterol levels Fulltext Access 5 Pages 2015
Characterization and preliminary anticonvulsant assessment of some 1,3,4-thiadiazole derivatives Fulltext Access 5 Pages 2015
Clonidine intensifies memantine cutaneous analgesia in response to local skin noxious pinprick in the rat Fulltext Access 5 Pages 2015
Ellagic acid enhances the antinociceptive action of venlafaxine in mouse acetic acid-induced pain: An isobolographic analysis Fulltext Access 5 Pages 2015
Effect of sodium selenite on chosen anti- and pro-oxidative parameters in rats treated with lithium: A pilot study Fulltext Access 5 Pages 2015