Tear-mediated delivery of nanoparticles through transcytosis of the lacrimal gland Fulltext Access 12 Pages 2015
Hyaluronic acid nanogels with enzyme-sensitive cross-linking group for drug delivery Fulltext Access 12 Pages 2015
Improving drug delivery to solid tumors: Priming the tumor microenvironment Fulltext Access 12 Pages 2015
Oxidative stress as an etiological factor and a potential treatment target of psychiatric disorders. Part 2. Depression, anxiety, schizophrenia and autism Fulltext Access 12 Pages 2015
Quantification of residual crystallinity in ball milled commercially sourced lactose monohydrate by thermo-analytical techniques and terahertz spectroscopy Fulltext Access 12 Pages 2015
Changes in the solid state of anhydrous and hydrated forms of sodium naproxen under different grinding and environmental conditions: Evidence of the formation of new hydrated forms Fulltext Access 12 Pages 2015
Partition coefficient vs. binding constant: How best to assess molecular lipophilicity Fulltext Access 12 Pages 2015
Particle engineering to enhance or lessen particle uptake by alveolar macrophages and to influence the therapeutic outcome Fulltext Access 12 Pages 2015
The chemistry and biological activity of heterocycle-fused quinolinone derivatives: A review Fulltext Access 12 Pages 2015
Design and optimization of hybrid of 2,4-diaminopyrimidine and arylthiazole scaffold as anticancer cell proliferation and migration agents Fulltext Access 12 Pages 2015
Design, synthesis and biological evaluation of quinazoline derivatives as anti-trypanosomatid and anti-plasmodial agents Fulltext Access 12 Pages 2015
Effect of different chemical bonds in pegylation of zinc protoporphyrin that affects drug release, intracellular uptake, and therapeutic effect in the tumor Fulltext Access 12 Pages 2015
The scope and sequence of growth factor delivery for vascularized bone tissue regeneration Fulltext Access 12 Pages 2015
Nucleic acid delivery into skin for the treatment of skin disease: Proofs-of-concept, potential impact, and remaining challenges Fulltext Access 12 Pages 2015
Engineering immunity: Modulating dendritic cell subsets and lymph node response to direct immune-polarization and vaccine efficacy Fulltext Access 12 Pages 2015
Recent approaches for reducing hemolytic activity of chemotherapeutic agents Fulltext Access 12 Pages 2015
A novel antitumour strategy using bidirectional autophagic vesicles accumulation via initiative induction and the terminal restraint of autophagic flux Fulltext Access 12 Pages 2015
A spatio-temporal cardiomyocyte targeted vector system for efficient delivery of therapeutic payloads to regress cardiac hypertrophy abating bystander effect Fulltext Access 12 Pages 2015
A novel localized co-delivery system with lapatinib microparticles and paclitaxel nanoparticles in a peritumorally injectable in situ hydrogel Fulltext Access 12 Pages 2015
Programmable insect cell carriers for systemic delivery of integrated cancer biotherapy Fulltext Access 12 Pages 2015
Living on pyrrolic foundations - Advances in natural and artificial bioactive pyrrole derivatives Fulltext Access 12 Pages 2015
Design, synthesis, and structure–activity-relationship of tetrahydrothiazolopyridine derivatives as potent smoothened antagonists Fulltext Access 12 Pages 2015
Design, synthesis and biological evaluation of novel pyrenyl derivatives as anticancer agents Fulltext Access 12 Pages 2015
Aminothiazoles: Hit to lead development to identify antileishmanial agents Fulltext Access 12 Pages 2015
Surface modification and local orientations of surface molecules in nanotherapeutics Fulltext Access 12 Pages 2015
Synthesis and in vitro biological evaluation of dihydroartemisinyl-chalcone esters Fulltext Access 12 Pages 2015
Spirooxindole-derived morpholine-fused-1,2,3-triazoles: Design, synthesis, cytotoxicity and apoptosis inducing studies Fulltext Access 12 Pages 2015
Synthesis of functionalized 3-, 5-, 6- and 8-aminoquinolines via intermediate (3-pyrrolin-1-yl)- and (2-oxopyrrolidin-1-yl)quinolines and evaluation of their antiplasmodial and antifungal activity Fulltext Access 12 Pages 2015
Synthesis and bioevaluation of pyrazole-benzimidazolone hybrids as novel human 4-Hydroxyphenylpyruvate dioxygenase inhibitors Fulltext Access 12 Pages 2015
Computational insights into function and inhibition of fatty acid amide hydrolase Fulltext Access 12 Pages 2015
Design, synthesis and biological activity of new amides derived from 3-methyl-3-phenyl-2,5-dioxo-pyrrolidin-1-yl-acetic acid Fulltext Access 12 Pages 2015
New derivatives of dehydroabietic acid target planktonic and biofilm bacteria in Staphylococcus aureus and effectively disrupt bacterial membrane integrity Fulltext Access 12 Pages 2015
Development of topical therapeutics for management of onychomycosis and other nail disorders: A pharmaceutical perspective Fulltext Access 13 Pages 2015
Novel biodegradable polyesteramide microspheres for controlled drug delivery in Ophthalmology Fulltext Access 13 Pages 2015
Recent progress in the drug development of coumarin derivatives as potent antituberculosis agents Fulltext Access 13 Pages 2015
Hybrid nanoparticles improve targeting to inflammatory macrophages through phagocytic signals Fulltext Access 13 Pages 2015
Synthesis and evaluation of thymidine kinase 1-targeting carboranyl pyrimidine nucleoside analogs for boron neutron capture therapy of cancer Fulltext Access 13 Pages 2015
Studies on indolizines. Evaluation of their biological properties as microtubule-interacting agents and as melanoma targeting compounds Fulltext Access 13 Pages 2015
Design, synthesis, and biological evaluation of 2-arylethenylquinoline derivatives as multifunctional agents for the treatment of Alzheimer's disease Fulltext Access 13 Pages 2015
Plasma membrane targeting by short chain sphingolipids inserted in liposomes improves anti-tumor activity of mitoxantrone in an orthotopic breast carcinoma xenograft model Fulltext Access 13 Pages 2015
Vibrational spectroscopy and microspectroscopy analyzing qualitatively and quantitatively pharmaceutical hot melt extrudates Fulltext Access 13 Pages 2015
Ion-exchange chromatography for the characterization of biopharmaceuticals Fulltext Access 13 Pages 2015
The quorum-sensing inhibiting effects of stilbenoids and their potential structure-activity relationship Fulltext Access 13 Pages 2015
Design, synthesis, biological evaluation and docking study of 4-isochromanone hybrids bearing N-benzyl pyridinium moiety as dual binding site acetylcholinesterase inhibitors Fulltext Access 13 Pages 2015
Novel thiazole-thiophene conjugates as adenosine receptor antagonists: Synthesis, biological evaluation and docking studies Fulltext Access 13 Pages 2015
Synthesis of natural phaeosphaeride A derivatives and an in vitro evaluation of their anti-cancer potential Fulltext Access 13 Pages 2015
Synthesis of aminoalkyl-substituted aurone derivatives as acetylcholinesterase inhibitors Fulltext Access 13 Pages 2015
Current and next generation influenza vaccines: Formulation and production strategies Fulltext Access 13 Pages 2015
Analytical techniques for characterization of cyclodextrin complexes in the solid state: A review Fulltext Access 13 Pages 2015
Sodium caprate-induced increases in intestinal permeability and epithelial damage are prevented by misoprostol Fulltext Access 13 Pages 2015
Embolization biomaterial reinforced with nanotechnology for an in-situ release of anti-angiogenic agent in the treatment of hyper-vascularized tumors and arteriovenous malformations Fulltext Access 13 Pages 2015
Insights into the roles of carrier microstructure in adhesive/carrier-based dry powder inhalation mixtures: Carrier porosity and fine particle content Fulltext Access 13 Pages 2015
Heterocyclic amine-modified polyethylenimine as gene carriers for transfection of mammalian cells Fulltext Access 13 Pages 2015
Current trends in biologics delivery to restore intervertebral disc anabolism Fulltext Access 13 Pages 2015
Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium Fulltext Access 13 Pages 2015
Exploring new selective 3-benzylquinoxaline-based MAO-A inhibitors: Design, synthesis, biological evaluation and docking studies Fulltext Access 13 Pages 2015
Coaxial electrohydrodynamic atomization: Microparticles for drug delivery applications Fulltext Access 13 Pages 2015
Potential mechanisms and applications of statins on osteogenesis: Current modalities, conflicts and future directions Fulltext Access 13 Pages 2015
A method of lyophilizing vaccines containing aluminum salts into a dry powder without causing particle aggregation or decreasing the immunogenicity following reconstitution Fulltext Access 13 Pages 2015
Solid lipid nanoparticles as nucleic acid delivery system: Properties and molecular mechanisms Fulltext Access 13 Pages 2015
In vivo delivery of peptides and Toll-like receptor ligands by mannose-functionalized polymeric nanoparticles induces prophylactic and therapeutic anti-tumor immune responses in a melanoma model Fulltext Access 13 Pages 2015
Myelosuppressive and hepatotoxic potential of leflunomide and methotrexate combination in a rat model of rheumatoid arthritis Fulltext Access 13 Pages 2015
Potential of aryl–urea–benzofuranylthiazoles hybrids as multitasking agents in Alzheimer's disease Fulltext Access 13 Pages 2015
Alcohol dose dumping: The influence of ethanol on hot-melt extruded pellets comprising solid lipids Fulltext Access 13 Pages 2015
Screening of synthetic and natural product databases: Identification of novel androgens and antiandrogens Fulltext Access 13 Pages 2015
Neuroprotective effects of a brain permeant 6-aminoquinoxaline derivative in cell culture conditions that model the loss of dopaminergic neurons in Parkinson disease Fulltext Access 13 Pages 2015
Potential of a low-cost bentonite for heavy metal abstraction from binary component system Fulltext Access 13 Pages 2015
Nanostructured lipid carrier system for topical delivery of terbinafine hydrochloride Fulltext Access 13 Pages 2015
Application of quality by design approach for intranasal delivery of rivastigmine loaded solid lipid nanoparticles: Effect on formulation and characterization parameters Fulltext Access 13 Pages 2015
Investigation and correlation of drug polymer miscibility and molecular interactions by various approaches for the preparation of amorphous solid dispersions Fulltext Access 13 Pages 2015
Engineering of a hybrid polymer–lipid nanocarrier for the nasal delivery of tenofovir disoproxil fumarate: Physicochemical, molecular, microstructural, and stability evaluation Fulltext Access 13 Pages 2015
Design, synthesis and biological evaluation of tricyclic diterpene derivatives as novel neuroprotective agents against ischemic brain injury Fulltext Access 13 Pages 2015
Melanoma-targeted delivery system (part 1): Design, synthesis and evaluation of releasable disulfide drug by glutathione Fulltext Access 13 Pages 2015
Design and synthesis of pyrazole–oxindole conjugates targeting tubulin polymerization as new anticancer agents Fulltext Access 13 Pages 2015
Biologically active compounds based on the privileged 2-imidazoline scaffold: The world beyond adrenergic/imidazoline receptor modulators Fulltext Access 13 Pages 2015
Design, synthesis and structure-activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities Fulltext Access 13 Pages 2015
Multi-target tacrine-coumarin hybrids: Cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease Fulltext Access 13 Pages 2015
4-Aminoquinoline-Pyrimidine hybrids: Synthesis, antimalarial activity, heme binding and docking studies Fulltext Access 13 Pages 2015
Hepatoma targeting peptide conjugated bio-reducible polymer complexed with oncolytic adenovirus for cancer gene therapy Fulltext Access 13 Pages 2015