Additive counteraction by α7 and α4β2-nAChRs of the hypotension and cardiac sympathovagal imbalance evoked by endotoxemia in male rats Fulltext Access 9 Pages 2018
Sesamin and sesamolin reduce amyloid-β toxicity in a transgenic Caenorhabditis elegans Fulltext Access 9 Pages 2018
Upregulation of EID3 sensitizes breast cancer cells to ionizing radiation-induced cellular senescence Fulltext Access 9 Pages 2018
Identification of N-Hydroxycinnamamide analogues and their bio-evaluation against breast cancer cell lines Fulltext Access 9 Pages 2018
miR-23c suppresses tumor growth of human hepatocellular carcinoma by attenuating ERBB2IP Fulltext Access 9 Pages 2018
MiR-148b-3p inhibits renal carcinoma cell growth and pro-angiogenic phenotype of endothelial cell potentially by modulating FGF2 Fulltext Access 9 Pages 2018
Long non-coding RNA TUG1 sponges miR-197 to enhance cisplatin sensitivity in triple negative breast cancer Fulltext Access 9 Pages 2018
Standardized Ginkgo biloba extract EGb 761® attenuates early brain injury following subarachnoid hemorrhage via suppressing neuronal apoptosis through the activation of Akt signaling Fulltext Access 9 Pages 2018
Salicornia ramosissima J. Woods seeds affected the normal regenerative function on carbon tetrachloride-induced liver and kidney injury Fulltext Access 9 Pages 2018
Rational in silico design of novel α-glucosidase inhibitory peptides and in vitro evaluation of promising candidates Fulltext Access 9 Pages 2018
Down-regulation of lncRNA ADAMTS9-AS2 contributes to gastric cancer development via activation of PI3K/Akt pathway Fulltext Access 9 Pages 2018
MiR-133a acts as an anti-oncogene in Hepatocellular carcinoma by inhibiting FOSL2 through TGF-β/Smad3 signaling pathway Fulltext Access 9 Pages 2018
miRNA-23a has effects to improve lung injury induced by sepsis in vitro and vivo study Fulltext Access 9 Pages 2018
MicroRNA-92a antagonism attenuates lipopolysaccharide (LPS)-induced pulmonary inflammation and injury in mice through suppressing the PTEN/AKT/NF-κB signaling pathway Fulltext Access 9 Pages 2018
Evaluation of different classes of histamine H1 and H2 receptor antagonist effects on neuropathic nociceptive behavior following tibial nerve transection in rats Fulltext Access 9 Pages 2018
Simvastatin-dependent actin cytoskeleton rearrangement regulates differentiation via the extracellular signal-regulated kinase-1/2 and p38 kinase pathways in rabbit articular chondrocytes Fulltext Access 9 Pages 2018
Morphological and chemical studies of artificial Andrographis paniculata polyploids Fulltext Access 9 Pages 2018
Buyang Huanwu Decoction ameliorates ischemic stroke by modulating multiple targets with multiple components: In vitro evidences Fulltext Access 9 Pages 2018
Constituent and effects of polysaccharides isolated from Sophora moorcroftiana seeds on lifespan, reproduction, stress resistance, and antimicrobial capacity in Caenorhabditis elegans Fulltext Access 9 Pages 2018
miR-27b and miR-34a enhance docetaxel sensitivity of prostate cancer cells through inhibiting epithelial-to-mesenchymal transition by targeting ZEB1 Fulltext Access 9 Pages 2018
The effect of ketorolac and triamcinolone acetonide on adipogenic and hepatogenic differentiation through miRNAs 16/15/195: Possible clinical application in regenerative medicine Fulltext Access 9 Pages 2018
6-Shogaol ameliorates diabetic nephropathy through anti-inflammatory, hyperlipidemic, anti-oxidative activity in db/db mice Fulltext Access 9 Pages 2018
Inhibition of miR-20 promotes proliferation and autophagy in articular chondrocytes by PI3K/AKT/mTOR signaling pathway Fulltext Access 9 Pages 2018
Diterpene ginkgolides meglumine injection protects against paraquat-induced lung injury and pulmonary fibrosis in rats Fulltext Access 9 Pages 2018
TGF-β regulates the ERK/MAPK pathway independent of the SMAD pathway by repressing miRNA-124 to increase MALAT1 expression in nasopharyngeal carcinoma Fulltext Access 9 Pages 2018
Cadmium nitrate-induced neuronal apoptosis is protected by N-acetyl-l-cysteine via reducing reactive oxygen species generation and mitochondria dysfunction Fulltext Access 9 Pages 2018
A standardized approach to the evaluation of antivirals against DNA viruses: Orthopox-, adeno-, and herpesviruses Fulltext Access 9 Pages 2018
Host derived exosomes-pathogens interactions: Potential functions of exosomes in pathogen infection Fulltext Access 9 Pages 2018
miRNA-1246 suppresses acute lung injury-induced inflammation and apoptosis via the NF-κB and Wnt/β-catenin signal pathways Fulltext Access 9 Pages 2018
Nur77 is a promoting factor in traumatic brain injury-induced nerve cell apoptosis Fulltext Access 9 Pages 2018
Attenuation of diethylnitrosamine (DEN) - Induced hepatic cancer in experimental model of Wistar rats by Carissa carandas embedded silver nanoparticles Fulltext Access 9 Pages 2018
Suppression of lncRNA-ATB prevents amyloid-β-induced neurotoxicity in PC12 cells via regulating miR-200/ZNF217 axis Fulltext Access 9 Pages 2018
Oxidative stress-elicited YY1 potentiates antioxidative response via enhancement of NRF2-driven transcriptional activity: A potential neuronal defensive mechanism against ischemia/reperfusion cerebral injury Fulltext Access 9 Pages 2018
Design, synthesis, in vitro, in vivo and in silico pharmacological characterization of antidiabetic N-Boc-l-tyrosine-based compounds Fulltext Access 9 Pages 2018
Encapsulation of verapamil and doxorubicin by MPEG-PLA to reverse drug resistance in ovarian cancer Fulltext Access 9 Pages 2018
MicroRNA-143a-3p modulates preadipocyte proliferation and differentiation by targeting MAPK7 Fulltext Access 9 Pages 2018
Capn4 expression is modulated by microRNA-520b and exerts an oncogenic role in prostate cancer cells by promoting Wnt/β-catenin signaling Fulltext Access 9 Pages 2018
Incretin hormones receptor signaling plays the key role in antidiabetic potential of PTY-2 against STZ-induced pancreatitis Fulltext Access 9 Pages 2018
Antinociceptive activity of ethanolic extract of Azadirachta indica A. Juss (Neem, Meliaceae) fruit through opioid, glutamatergic and acid-sensitive ion pathways in adult zebrafish (Danio rerio) Fulltext Access 9 Pages 2018
LncRNA THOR increases the stemness of gastric cancer cells via enhancing SOX9 mRNA stability Fulltext Access 9 Pages 2018
LINC00657 played oncogenic roles in esophageal squamous cell carcinoma by targeting miR-615-3p and JunB Fulltext Access 9 Pages 2018
microRNA-300/NAMPT regulates inflammatory responses through activation of AMPK/mTOR signaling pathway in neonatal sepsis Fulltext Access 9 Pages 2018
Therapeutic effects of honokiol on motor impairment in hemiparkinsonian mice are associated with reversing neurodegeneration and targeting PPARγ regulation Fulltext Access 9 Pages 2018
Effect of Hypericum humifusum aqueous and methanolic leaf extracts on biochemical and histological parameters in adult rats Fulltext Access 9 Pages 2018
Cinobufacini protects against paclitaxel-induced peripheral neuropathic pain and suppresses TRPV1 up-regulation and spinal astrocyte activation in rats Fulltext Access 9 Pages 2018
miR-217 represses TGF-β1-induced airway smooth muscle cell proliferation and migration through targeting ZEB1 Fulltext Access 9 Pages 2018
MicroRNA-504 functions as a tumor suppressor in hepatocellular carcinoma through inhibiting Frizzled-7-mediated-Wnt/β-catenin signaling Fulltext Access 9 Pages 2018
LncRNA HOTAIR suppresses TNF-α induced apoptosis of nucleus pulposus cells by regulating miR-34a/Bcl-2 axis Fulltext Access 9 Pages 2018
MicroRNA-135a-3p is downregulated and serves as a tumour suppressor in ovarian cancer by targeting CCR2 Fulltext Access 9 Pages 2018
Mitochondrial DNA content reduction induces aerobic glycolysis and reversible resistance to drug-induced apoptosis in SW480 colorectal cancer cells Fulltext Access 9 Pages 2018
Long non-coding RNA OIP5-AS1 functions as an oncogene in lung adenocarcinoma through targeting miR-448/Bcl-2 Fulltext Access 9 Pages 2018
Acute toxicity screening of different extractions, components and constituents of Polygonum multiflorum Thunb. on zebrafish (Danio rerio) embryos in vivo Fulltext Access 9 Pages 2018
LncRNA SNHG20 promotes cell proliferation and invasion via miR-140-5p-ADAM10 axis in cervical cancer Fulltext Access 9 Pages 2018
Comparative study of effects of assemblages AII and BIV of Giardia duodenalis on mucosa and microbiota of the small intestine in mice Fulltext Access 9 Pages 2018
Bavachin induces the apoptosis of multiple myeloma cell lines by inhibiting the activation of nuclear factor kappa B and signal transducer and activator of transcription 3 Fulltext Access 9 Pages 2018
Antihyperlipidemic effect of a Rhamnus alaternus leaf extract in Triton-induced hyperlipidemic rats and human HepG2 cells Fulltext Access 9 Pages 2018
Querectin improves myelin repair of optic chiasm in lyolecithin-induced focal demyelination model Fulltext Access 9 Pages 2018
Inotodiol suppresses proliferation of breast cancer in rat model of type 2 diabetes mellitus via downregulation of β-catenin signaling Fulltext Access 9 Pages 2018
Two sesquiterpene aminoquinones protect against oxidative injury in HaCaT keratinocytes via activation of AMPKα/ERK-Nrf2/ARE/HO-1 signaling Fulltext Access 9 Pages 2018
Resveratrol inhibits proliferation, migration and invasion via Akt and ERK1/2 signaling pathways in renal cell carcinoma cells Fulltext Access 9 Pages 2018
β-Amyrin, the cannabinoid receptors agonist, abrogates mice brain microglial cells inflammation induced by lipopolysaccharide/interferon-γâ¯and regulates MÏ1/MÏ2 balances Fulltext Access 9 Pages 2018
Naringenin improve hepatitis C virus infection induced insulin resistance by increase PTEN expression via p53-dependent manner Fulltext Access 9 Pages 2018
Curcumin protects against hepatic stellate cells activation and migration by inhibiting the CXCL12/CXCR4 biological axis in liver fibrosisï¼A study in vitro and in vivo Fulltext Access 9 Pages 2018
SALL4 promotes osteoblast differentiation by deactivating NOTCH2 signaling Fulltext Access 9 Pages 2018
Activation of PPARγ mediates icaritin-induced cell cycle arrest and apoptosis in glioblastoma multiforme Fulltext Access 9 Pages 2018
Micro RNA-1298 opposes the effects of chronic oxidative stress on human trabecular meshwork cells via targeting on EIF4E3 Fulltext Access 9 Pages 2018
Interferon lambda (IFN-λ) efficiently blocks norovirus transmission in a mouse model Fulltext Access 9 Pages 2018
Large-scale screening of circulating microRNAs in individuals with HIV-1 mono-infections reveals specific liver damage signatures Fulltext Access 9 Pages 2018
Construction of an attenuated goatpox virus AV41 strain by deleting the TK gene and ORF8-18 Fulltext Access 9 Pages 2018
CD24 and Fc fusion protein protects SIVmac239-infected Chinese rhesus macaque against progression to AIDS Fulltext Access 9 Pages 2018
Alkyl-imino sugars inhibit the pro-oncogenic ion channel function of human papillomavirus (HPV) E5 Fulltext Access 9 Pages 2018
Comorbid thyroid disease in patients with major depressive disorder - results from the European Group for the Study of Resistant Depression (GSRD) Fulltext Access 9 Pages 2018
Ononitol monohydrate enhances PRDM16 & UCP-1 expression, mitochondrial biogenesis and insulin sensitivity via STAT6 and LTB4R in maturing adipocytes Fulltext Access 9 Pages 2018
Differential ratios of fish/corn oil ameliorated the colon carcinoma in rat by altering intestinal intraepithelial CD8+ T lymphocytes, dendritic cells population and modulating the intracellular cytokines Fulltext Access 9 Pages 2018
Phytochemical profile and mechanisms involved in the anti-nociception caused by the hydroethanolic extract obtained from Tocoyena formosa (Cham. & Schltdl.) K. Schum (Jenipapo-bravo) leaves in mice Fulltext Access 9 Pages 2018
Thymelaea lythroides extract attenuates microglial activation and depressive-like behavior in LPS-induced inflammation in adult male rats Fulltext Access 9 Pages 2018
Jobelyn® attenuates inflammatory responses and neurobehavioural deficits associated with complete Freund-adjuvant-induced arthritis in mice Fulltext Access 9 Pages 2018
Down-regulation of LGR6 promotes bone fracture recovery using bone marrow stromal cells Fulltext Access 9 Pages 2018
Taurine enhances spermatogenic function and antioxidant defense mechanisms in testes and epididymis of L-NAME-induced hypertensive rats Fulltext Access 9 Pages 2018
Disulfiram/copper causes ROS levels alteration, cell cycle inhibition, and apoptosis in acute myeloid leukaemia cell lines with modulation in the expression of related genes Fulltext Access 9 Pages 2018
Autophagy induction by hispidulin provides protection against sevoflurane-induced neuronal apoptosis in aged rats Fulltext Access 9 Pages 2018
Co-targeting poly(ADP-ribose) polymerase (PARP) and histone deacetylase (HDAC) in triple-negative breast cancer: Higher synergism in BRCA mutated cells Fulltext Access 9 Pages 2018
Vitexin inhibits inflammation in murine ovalbumin-induced allergic asthma Fulltext Access 9 Pages 2018
Extract of Citrus maxima (pummelo) leaves improve hepatoprotective activity in Wistar rats submitted to the induction of non-alcoholic hepatic steatosis Fulltext Access 9 Pages 2018
NF-κB-induced WIP1 expression promotes colorectal cancer cell proliferation through mTOR signaling Fulltext Access 9 Pages 2018
PLACID study: A randomized trial comparing the efficacy and safety of inhaled loxapine versus intramuscular aripiprazole in acutely agitated patients with schizophrenia or bipolar disorder Fulltext Access 9 Pages 2018
Combination of novel DR5 targeting agonistic scFv antibody TR2-3 with cisplatin shows enhanced synergistic antitumor activity in vitro and in vivo Fulltext Access 9 Pages 2018
Isoferulic acid attenuates methylglyoxal-induced apoptosis in INS-1 rat pancreatic β-cell through mitochondrial survival pathways and increasing glyoxalase-1 activity Fulltext Access 9 Pages 2018
Transferrin and tocopheryl-polyethylene glycol-succinate dual ligands decorated, cisplatin loaded nano-sized system for the treatment of lung cancer Fulltext Access 9 Pages 2018
HDACis (class I), cancer stem cell, and phytochemicals: Cancer therapy and prevention implications Fulltext Access 9 Pages 2018
Steviol slows renal cyst growth by reducing AQP2 expression and promoting AQP2 degradation Fulltext Access 9 Pages 2018
Natural products berberine and curcumin exhibited better ameliorative effects on rats with non-alcohol fatty liver disease than lovastatin Fulltext Access 9 Pages 2018
Halofuginone attenuates intervertebral discs degeneration by suppressing collagen I production and inactivating TGFβ and NF-кB pathway Fulltext Access 9 Pages 2018
The water extract of tutsan (Hypericum androsaemum L.) red berries exerts antidepressive-like effects and in vivo antioxidant activity in a mouse model of post-stroke depression Fulltext Access 9 Pages 2018
Pedunculoside, a novel triterpene saponin extracted from Ilex rotunda, ameliorates high-fat diet induced hyperlipidemia in rats Fulltext Access 9 Pages 2018