Glucocorticoids and β2-agonists regulate the pathologic metabolism of hyaluronic acid in COPD Fulltext Access 21 Pages 2018
Overexpression of GRIM-19 accelerates radiation-induced osteosarcoma cells apoptosis by p53 stabilization Fulltext Access 21 Pages 2018
HMGB1 promotes the starvation-induced autophagic degradation of α-synuclein in SH-SY5Y cells Atg 5-dependently Fulltext Access 21 Pages 2018
Role of rho-kinase (ROCK) in tonic but not phasic contraction in the frog stomach smooth muscle Fulltext Access 21 Pages 2018
Combination effect naringin and pravastatin in lipid profile and glucose in obese rats Fulltext Access 21 Pages 2018
Astragaloside IV improves vascular endothelial dysfunction by inhibiting the TLR4/NF-κB signaling pathway Fulltext Access 21 Pages 2018
The detection and quantification, in vivo and in real time, of hydrogen sulfide in ethanol-induced lesions in rat stomachs using an ion sensitive electrode Fulltext Access 21 Pages 2018
Effect of adding roflumilast or ciclesonide to glycopyrronium on lung volumes and exercise tolerance in patients with severe COPD: A pilot study Fulltext Access 21 Pages 2018
Population change of Trillium govanianum (Melanthiaceae) amid altered indigenous harvesting practices in the Indian Himalayas Fulltext Access 21 Pages 2018
The inhibitory effect of Filipendula ulmaria (L.) Maxim. on colorectal carcinogenesis induced in rats by methylnitrosourea Fulltext Access 21 Pages 2018
Antioxidant, anti-inflammatory and gastroprotective activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench Fulltext Access 21 Pages 2018
Growth arrest and DNA-damage-inducible 45 beta (GADD45β) deletion suppresses testosterone-induced prostate hyperplasia in mice Fulltext Access 21 Pages 2018
Impact of doxofylline compared to theophylline in asthma: A pooled analysis of functional and clinical outcomes from two multicentre, double-blind, randomized studies (DOROTHEO 1 and DOROTHEO 2) Fulltext Access 21 Pages 2018
Role of p62/SQSTM1 in lipopolysaccharide (LPS)-induced mucus hypersecretion in bronchial epithelial cells Fulltext Access 21 Pages 2018
Triptolide-induced hepatotoxicity can be alleviated when combined with Panax notoginseng saponins and Catapol Fulltext Access 22 Pages 2018
NF-κB and JNK mediated apoptosis and G0/G1 arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis Fulltext Access 22 Pages 2018
Ethnopharmacology, phytochemistry, and pharmacology of Cornus officinalis Sieb. et Zucc Fulltext Access 22 Pages 2018
Isolation and pharmacological characterization of a new cytotoxic L-amino acid oxidase from Bungarus multicinctus snake venom Fulltext Access 22 Pages 2018
Development of an in vitro screening method of acute cytotoxicity of the pyrrolizidine alkaloid lasiocarpine in human and rodent hepatic cell lines by increasing susceptibility Fulltext Access 22 Pages 2018
O-Glycosylation with O-linked β-N-acetylglucosamine increases vascular contraction: Possible modulatory role on Interleukin-10 signaling pathway Fulltext Access 22 Pages 2018
Sini decoction alleviates E. coli induced acute lung injury in mice via equilibrating ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis Fulltext Access 22 Pages 2018
TNNT1 facilitates proliferation of breast cancer cells by promoting G1/S phase transition Fulltext Access 22 Pages 2018
Electroacupuncture ameliorates poloxamer 407-induced hyperlipidemia through suppressing hepatic SREBP-2 expression in rats Fulltext Access 22 Pages 2018
The passive avoidance memory improving effect of curcumin in young adult mice: Considering hippocampal MMP-2, MMP-9 and Akt/GSK3β Fulltext Access 22 Pages 2018
A double-blind, randomized, placebo-controlled, three-way crossover clinical investigation to evaluate the effect of IQP-VV-102 on postprandial blood glucose reduction Fulltext Access 22 Pages 2018
Sea cucumber (Isostichopus badionotus) body-wall preparations exert anti-inflammatory activity in vivo Fulltext Access 22 Pages 2018
The importance of TCF4 gene in the etiology of recurrent depressive disorders Fulltext Access 22 Pages 2018
Evaluation of selenium nanoparticles and doxorubicin effect against hepatocellular carcinoma rat model cytogenetic toxicity and DNA damage Fulltext Access 22 Pages 2018
Affecting NF-κB cell signaling pathway in chronic lymphocytic leukemia by dendrimers-based nanoparticles Fulltext Access 22 Pages 2018
Pharmacologic targeting of the ATX/LPA axis attenuates bleomycin-induced pulmonary fibrosis Fulltext Access 22 Pages 2018
Nicotine modulates contextual fear extinction through changes in ventral hippocampal GABAergic function Fulltext Access 22 Pages 2018
The reversal effect of physical exercise on aging-related increases in APPL2 content in skeletal muscle Fulltext Access 22 Pages 2018
Neuroendocrine and inflammatory responses to DHEA administration in young healthy women Fulltext Access 22 Pages 2018
Blood-brain barrier integrity in a mouse model of Alzheimer's disease with or without acute 3D6 immunotherapy Fulltext Access 22 Pages 2018
Extrapolation of the Hepatic Clearance of Drugs in the Absence of Albumin In Vitro to That in the Presence of Albumin In Vivo: Comparative Assessement of 2 Extrapolation Models Based on the Albumin-Mediated Hepatic Uptake Theory and Limitations and Mech Fulltext Access 22 Pages 2018
The effect of N-acetylcysteine or bupropion on methamphetamine self-administration and methamphetamine-triggered reinstatement of female rats Fulltext Access 22 Pages 2018
Spontaneous activity, singly bound states and the impact of alpha1Phe64 mutation on GABAAR gating in the novel kinetic model based on the single-channel recordings Fulltext Access 22 Pages 2018
Xanthone-rich extract from Gentiana dinarica transformed roots and its active component norswertianin induce autophagy and ROS-dependent differentiation of human glioblastoma cell line Fulltext Access 22 Pages 2018
Honeysuckle-encoded microRNA2911 inhibits Enterovirus 71 replication via targeting VP1 gene Fulltext Access 22 Pages 2018
Pharmacokinetics, Tolerability, and Bioequivalence of Two Formulations of Rotigotine in Healthy Chinese Subjects Fulltext Access 22 Pages 2018
TNF-alpha and TNF-R1 regulate bupivacaine-induced apoptosis in spinal cord dorsal root ganglion neuron Fulltext Access 22 Pages 2018
Thioredoxin-1 downregulation in the nucleus accumbens promotes methamphetamine-primed reinstatement in mice Fulltext Access 22 Pages 2018
Anticonvulsive effects of protodioscin against pilocarpine-induced epilepsy Fulltext Access 22 Pages 2018
MAPKs-mediated modulation of the myocyte voltage-gated K+ channels is involved in ethanol-induced rat coronary arterial contraction Fulltext Access 22 Pages 2018
Antithrombin III-Binding Site Analysis of Low-Molecular-Weight Heparin Fractions Fulltext Access 22 Pages 2018
Danshensu prevents hypoxic pulmonary hypertension in rats by inhibiting the proliferation of pulmonary artery smooth muscle cells via TGF-β-smad3-associated pathway Fulltext Access 22 Pages 2018
Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes Fulltext Access 22 Pages 2018
Adenine accelerated the diabetic wound healing by PPAR delta and angiogenic regulation Fulltext Access 22 Pages 2018
Phytochemistry, pharmacology, quality control and future research of Forsythia suspensa (Thunb.) Vahl: A review Fulltext Access 22 Pages 2018
Recent advances in galactose-engineered nanocarriers for the site-specific delivery of siRNA and anticancer drugs Fulltext Access 22 Pages 2018
Ethnomedicobotanical study of indigenous knowledge on medicinal plants used for the treatment of reproductive problems in Nalbari district, Assam, India Fulltext Access 22 Pages 2018
Rattling the border wall: Pathophysiological implications of functional and proteomic venom variation between Mexican and US subspecies of the desert rattlesnake Crotalus scutulatus Fulltext Access 22 Pages 2018
Rising trade, declining stocks: The global gugul (Commiphora wightii) trade Fulltext Access 22 Pages 2018
Immune modulation of a lipid-soluble extract of Pinellia pedatisecta Schott in the tumor microenvironment of an HPV+ tumor-burdened mouse model Fulltext Access 22 Pages 2018
In vivo wound-healing activity of Euphorbia characias subsp. wulfenii: Isolation and quantification of quercetin glycosides as bioactive compounds Fulltext Access 22 Pages 2018
Effectiveness of memantine on depression-like behavior, memory deficits and brain mRNA levels of BDNF and TrkB in rats subjected to repeated unpredictable stress Fulltext Access 22 Pages 2018
Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin-induced diabetic nephropathy in mice Fulltext Access 23 Pages 2018
The role of monoamines in the development of Alzheimer's disease and neuroprotective effect of a proline rich polypeptide Fulltext Access 23 Pages 2018
Plasma biomarkers in a placebo-controlled trial comparing tDCS and escitalopram efficacy in major depression Fulltext Access 23 Pages 2018
Aripiprazole as an adjuvant treatment for obsessive and compulsive symptoms in manic phase of bipolar disorder: A randomized, double-blind, placebo-controlled clinical trial Fulltext Access 23 Pages 2018
Gray matter volume showed dynamic alterations in methamphetamine users at 6 and 12Â months abstinence: A longitudinal voxel-based morphometry study Fulltext Access 23 Pages 2018
Lacosamide protects striatal and hippocampal neurons from in vitro ischemia without altering physiological synaptic plasticity Fulltext Access 23 Pages 2018
Synthesis, Characterization, and Crystal Chemistry of Tasimelteon, a Melatonin Agonist, in Its Anhydrous and Hemihydrate Forms Fulltext Access 23 Pages 2018
Immunomodulatory effects of BRAF and MEK inhibitors: Implications for Melanoma therapy Fulltext Access 23 Pages 2018
Ciprofloxacin-mediated induction of S-phase cell cycle arrest and apoptosis in COLO829 melanoma cells Fulltext Access 23 Pages 2018
Treatment with long acting muscarinic antagonists stimulates serum levels of irisin in patients with COPD Fulltext Access 23 Pages 2018
An antidepressant-related pharmacological signature for positive allosteric modulators of α2/3-containing GABAA receptors Fulltext Access 23 Pages 2018
The silencing of replication protein A1 induced cell apoptosis via regulating Caspase 3 Fulltext Access 23 Pages 2018
MiR-182 alleviates the development of cyanotic congenital heart disease by suppressing HES1 Fulltext Access 23 Pages 2018
A Comparative study for striatal-direct and -indirect pathway neurons to DA depletion-induced lesion in a PD rat model Fulltext Access 23 Pages 2018
Understanding the biology of HER3 receptor as a therapeutic target in human cancer Fulltext Access 23 Pages 2018
Sulfur-containing compounds from the roots of Ferula latisecta and their cytotoxic activities Fulltext Access 23 Pages 2018
Anti-angiogenic effects of Qingdu granule on breast cancer through inhibiting NFAT signaling pathway Fulltext Access 23 Pages 2018
Investigation of constituents from Cinnamomum camphora (L.) J. Presl and evaluation of their anti-inflammatory properties in lipopolysaccharide-stimulated RAW 264.7 macrophages Fulltext Access 23 Pages 2018
Sustainable harvest, people and pandas: Assessing a decade of managed wild harvest and trade in Schisandra sphenanthera Fulltext Access 23 Pages 2018
Botany, ethnomedicines, phytochemistry and pharmacology of Himalayan paeony (Paeonia emodi Royle.) Fulltext Access 23 Pages 2018
Pomegranate polyphenols and urolithin A inhibit α-glucosidase, dipeptidyl peptidase-4, lipase, triglyceride accumulation and adipogenesis related genes in 3T3-L1 adipocyte-like cells Fulltext Access 23 Pages 2018
Anethum graveolens (dill) - A medicinal herb induces apoptosis and cell cycle arrest in HepG2 cell line Fulltext Access 23 Pages 2018
Substituting one Paris for another? In vitro cytotoxic and in vivo antitumor activities of Paris forrestii, a substitute of Paris polyphylla var. yunnanensis Fulltext Access 23 Pages 2018
Diuretic herb Gomphrena celosioides Mart. (Amaranthaceae) promotes sustained arterial pressure reduction and protection from cardiac remodeling on rats with renovascular hypertension Fulltext Access 23 Pages 2018
Telfairia occidentalis Hook.f. - associated haematopoietic effect is mediated by cytokines but independent of testosterone: A preliminary report Fulltext Access 23 Pages 2018
The Chinese herbal formula Zhibai Dihuang Granule treat Yin-deficiency-heat syndrome rats by regulating the immune responses Fulltext Access 23 Pages 2018
Anti-HIV activity of southern African plants: Current developments, phytochemistry and future research Fulltext Access 23 Pages 2018
Cannabinoid-1 receptor neutral antagonist reduces binge-like alcohol consumption and alcohol-induced accumbal dopaminergic signaling Fulltext Access 23 Pages 2018
Impact of calcium-sensitive dyes on the beating properties and pharmacological responses of human iPS-derived cardiomyocytes using the calcium transient assay Fulltext Access 23 Pages 2018
Ropivacaine relieves pain and prevents chondrocyte degradation probably through Calcineurin/NFAT1 signaling pathway in osteoarthritis rats Fulltext Access 23 Pages 2018
Knockdown of NLRC5 inhibits renal fibroblast activation via modulating TGF-β1/Smad signaling pathway Fulltext Access 23 Pages 2018
Application of E75 peptide vaccine in breast cancer patients: A systematic review and meta-analysis Fulltext Access 23 Pages 2018
Hypomethylation of specific CpG sites in the promoter region of steroidogeneic genes (GATA6 and StAR) in prenatally androgenized rats Fulltext Access 23 Pages 2018
Shikonin enhances sensitization of gefitinib against wild-type EGFR non-small cell lung cancer via inhibition PKM2/stat3/cyclinD1 signal pathway Fulltext Access 23 Pages 2018
Apigenin-7-O-β-d-(-6â³-p-coumaroyl)-glucopyranoside pretreatment attenuates myocardial ischemia/reperfusion injury via activating AMPK signaling Fulltext Access 23 Pages 2018
Titanium dioxide nanoparticle stimulating pro-inflammatory responses in vitro and in vivo for inhibited cancer metastasis Fulltext Access 23 Pages 2018
In vivo and in vitro anti-inflammatory effects of Sophora flavescens residues Fulltext Access 23 Pages 2018
Exploring the impact of parthenolide as anti-quorum sensing and anti-biofilm agent against Pseudomonas aeruginosa Fulltext Access 23 Pages 2018
Silencing calreticulin gene might protect cardiomyocytes from angiotensin II-induced apoptosis Fulltext Access 23 Pages 2018