AMPK attenuates ventricular remodeling and dysfunction following aortic banding in mice via the Sirt3/Oxidative stress pathway Fulltext Access 8 Pages 2017
Z-505 hydrochloride, an orally active ghrelin agonist, attenuates the progression of cancer cachexia via anabolic hormones in Colon 26 tumor-bearing mice Fulltext Access 8 Pages 2017
Osthole inhibits intimal hyperplasia by regulating the NF-κB and TGF-β1/Smad2 signalling pathways in the rat carotid artery after balloon injury Fulltext Access 8 Pages 2017
Interference of ursolic acid treatment with glioma growth: An in vitro and in vivo study Fulltext Access 8 Pages 2017
Phosphoproteome and transcription factor activity profiling identify actions of the anti-inflammatory agent UTL-5g in LPS stimulated RAW 264.7 cells including disrupting actin remodeling and STAT-3 activation Fulltext Access 8 Pages 2017
JKB-122 is effective, alone or in combination with prednisolone in Con A-induced hepatitis Fulltext Access 8 Pages 2017
Pharmacological characterization of the interaction between umeclidinium and vilanterol in human bronchi Fulltext Access 8 Pages 2017
The PPARα activator fenofibrate inhibits voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells Fulltext Access 8 Pages 2017
N-(2-morpholin-4-yl-ethyl)-2-(1naphthyloxy)acetamide inhibits the chronic constriction injury-generated hyperalgesia via the antagonism of sigma-1 receptors Fulltext Access 8 Pages 2017
Tetrandrine cardioprotection in ischemia-reperfusion (I/R) injury via JAK3/STAT3/Hexokinase II Fulltext Access 8 Pages 2017
Peripheral and central sites of action for anti-allodynic activity induced by the bifunctional opioid/NPFF receptors agonist BN-9 in inflammatory pain model Fulltext Access 8 Pages 2017
Cannabinoid CB1 receptor inverse agonist MJ08 stimulates glucose production via hepatic sympathetic innervation in rats Fulltext Access 8 Pages 2017
A new mechanism of inhibition of IL-1β secretion by celastrol through the NLRP3 inflammasome pathway Fulltext Access 8 Pages 2017
Citrus nomilin down-regulates TNF-α-induced proliferation of aortic smooth muscle cells via apoptosis and inhibition of IκB Fulltext Access 8 Pages 2017
Angeli's Salt, a nitroxyl anion donor, reverses endothelin-1 mediated vascular dysfunction in murine aorta Fulltext Access 8 Pages 2017
A newly synthesized Ligustrazine stilbene derivative inhibits PDGF-BB induced vascular smooth muscle cell phenotypic switch and proliferation via delaying cell cycle progression Fulltext Access 8 Pages 2017
A pyridone derivative activates SERCA2a by attenuating the inhibitory effect of phospholamban Fulltext Access 8 Pages 2017
Edaravone is a candidate agent for spinal muscular atrophy: In vitro analysis using a human induced pluripotent stem cells-derived disease model Fulltext Access 8 Pages 2017
A novel partial agonist of GPBA reduces blood glucose level in a murine glucose tolerance test Fulltext Access 8 Pages 2017
Inhibition of morphine tolerance by MrgC receptor via modulation of interleukin-1β and matrix metalloproteinase 9 in dorsal root ganglia in rats Fulltext Access 8 Pages 2017
Regulation of voltage gated calcium channels by GPCRs and post-translational modification Fulltext Access 8 Pages 2017
Correcting CFTR folding defects by small-molecule correctors to cure cystic fibrosis Fulltext Access 8 Pages 2017
Minimally invasive probes for programmed microfluidic delivery of molecules in vivo Fulltext Access 8 Pages 2017
Hypolipemiant and antioxidant effects of Eugenia brasiliensis in an animal model of coconut oil-induced hypertriglyceridemia Fulltext Access 8 Pages 2017
The therapeutic potential of CFTR modulators for COPD and other airway diseases Fulltext Access 8 Pages 2017
GABAB receptor modulation - to B or not to be B a pro-cognitive medicine? Fulltext Access 8 Pages 2017
Identification of C-geranylated flavonoids from Paulownia catalpifolia Gong Tong fruits by HPLC-DAD-ESI-MS/MS and their anti-aging effects on 2BS cells induced by H2O2 Fulltext Access 8 Pages 2017
A lipophilic prodrug of Danshensu: preparation, characterization, and in vitro and in vivo evaluation Fulltext Access 8 Pages 2017
Synthesis and evaluation of 2-cyano-3, 12-dioxooleana-1, 9(11)-en-28-oate-13β, 28-olide as a potent anti-inflammatory agent for intervention of LPS-induced acute lung injury Fulltext Access 8 Pages 2017
Polymyxin B as an inhibitor of lipopolysaccharides contamination of herb crude polysaccharides in mononuclear cells Fulltext Access 8 Pages 2017
Anti-colorectal cancer effects of tripolinolate A from Tripolium vulgare Fulltext Access 8 Pages 2017
Identification of human cytochrome P450 and UGT enzymes involved in the metabolism of ferulic acid, a major bioactive component in traditional Chinese medicines Fulltext Access 8 Pages 2017
Neuroprotective effects of Yiqihuoxue calm wind capsule on ischemic stroke in rats Fulltext Access 8 Pages 2017
Early intervention with Didang decoction delays macrovascular lesions in diabetic rats through regulating AMP-activated protein kinase signaling pathway Fulltext Access 8 Pages 2017
Anticancer carbazole alkaloids and coumarins from Clausena plants: A review Fulltext Access 8 Pages 2017
MiR-129 inhibits cell proliferation and metastasis by targeting ETS1 via PI3K/AKT/mTOR pathway in prostate cancer Fulltext Access 8 Pages 2017
Licochalcone A induces morphological and biochemical alterations in Schistosoma mansoni adult worms Fulltext Access 8 Pages 2017
Effectiveness of bis(phenylimidazoselenazolyl) diselenide on a mouse model of inflammatory nociception Fulltext Access 8 Pages 2017
ABT737 induces mitochondrial pathway apoptosis and mitophagy by regulating DRP1-dependent mitochondrial fission in human ovarian cancer cells Fulltext Access 8 Pages 2017
Long non-coding RNA ANRIL promotes carcinogenesis via sponging miR-199a in triple-negative breast cancer Fulltext Access 8 Pages 2017
Deficiency of N-acetyltransferase increases the interactions of isoniazid with endobiotics in mouse liver Fulltext Access 8 Pages 2017
Drug repurposing strategy against Trypanosoma cruzi infection: In vitro and in vivo assessment of the activity of metronidazole in mono- and combined therapy Fulltext Access 8 Pages 2017
Protective effects of Forsythoside A on amyloid beta-induced apoptosis in PC12 cells by downregulating acetylcholinesterase Fulltext Access 8 Pages 2017
The impact of α-Lipoic acid on cell viability and expression of nephrin and ZNF580 in normal human podocytes Fulltext Access 8 Pages 2017
Hydroxycamptothecin prevents intraarticular scar adhesion by activating the PERK signal pathway Fulltext Access 8 Pages 2017
SHC004-221A1, a novel tyrosine kinase, potently inhibits T315I mutant BCR-ABL in chronic myeloid leukemia Fulltext Access 8 Pages 2017
Antiproliferative activity of Alisol B in MDA-MB-231 cells is mediated by apoptosis, dysregulation of mitochondrial functions, cell cycle arrest and generation of reactive oxygen species Fulltext Access 8 Pages 2017
Magnesium Isoglycyrrhizinate attenuates lipopolysaccharide-induced depressive-like behavior in mice Fulltext Access 8 Pages 2017
Original articleIncreased intracellular Ca2+ decreases cisplatin resistance by regulating iNOS expression in human ovarian cancer cells Fulltext Access 8 Pages 2017
The arguments for and against cannabinoids application in glaucomatous retinopathy Fulltext Access 8 Pages 2017
Apelin-13 protects rat primary cortical glia-neuron co-culture against pentylenetetrazole-induced toxicity Fulltext Access 8 Pages 2017
Biological properties of citral and its potential protective effects against cytotoxicity caused by aspirin in the IEC-6 cells Fulltext Access 8 Pages 2017
Inositol hexa phosphoric acid (phytic acid), a nutraceuticals, attenuates iron-induced oxidative stress and alleviates liver injury in iron overloaded mice Fulltext Access 8 Pages 2017
Hydroxysafflor yellow A cardioprotection in ischemia-reperfusion (I/R) injury mainly via Akt/hexokinase II independent of ERK/GSK-3β pathway Fulltext Access 8 Pages 2017
Tinospora cordifolia extract attenuates cadmium-induced biochemical and histological alterations in the heart of male Wistar rats Fulltext Access 8 Pages 2017
Epiisopiloturine hydrochloride, an imidazole alkaloid isolated from Pilocarpus microphyllus leaves, protects against naproxen-induced gastrointestinal damage in rats Fulltext Access 8 Pages 2017
Propofol inhibits LPS-induced apoptosis in lung epithelial cell line, BEAS-2B Fulltext Access 8 Pages 2017
Anti-diabetic effect of three new norditerpenoid alkaloids in vitro and potential mechanism via PI3K/Akt signaling pathway Fulltext Access 8 Pages 2017
Aryl hydrocarbon receptor activation modulates CD8αα+TCRαβ+ IELs and suppression of colitis manifestations in mice Fulltext Access 8 Pages 2017
Saponins from the roots of Platycodon grandiflorum ameliorate high fat diet-induced non-alcoholic steatohepatitis Fulltext Access 8 Pages 2017
Taspine derivative 12k suppressed A549 cell migration through the Wnt/β-catenin and EphrinB2 signaling pathway Fulltext Access 8 Pages 2017
Diospyros lotus leaf and grapefruit stem extract synergistically ameliorate atopic dermatitis-like skin lesion in mice by suppressing infiltration of mast cells in skin lesions Fulltext Access 8 Pages 2017
Hepatoprotective efficacy of Nigella sativa seeds dietary supplementation against lead acetate-induced oxidative damage in rabbit - Purification and characterization of glutathione peroxidase Fulltext Access 8 Pages 2017
Protective effects of N-acetylcystein and atorvastatin against renal and hepatic injury in a rat model of intestinal ischemia-reperfusion Fulltext Access 8 Pages 2017
Kukoamine A attenuates insulin resistance and fatty liver through downregulation of Srebp-1c Fulltext Access 8 Pages 2017
Pharmacodynamics of S-dimethylarsino-glutathione, a putative metabolic intermediate of inorganic arsenic, in mice Fulltext Access 8 Pages 2017
Nobiletin inhibits oxidized-LDL mediated expression of Tissue Factor in human endothelial cells through inhibition of NF-κB Fulltext Access 8 Pages 2017
The N-terminal region of organic anion transporting polypeptide 1B3 (OATP1B3) plays an essential role in regulating its plasma membrane trafficking Fulltext Access 8 Pages 2017
Hydroxyurea inhibits parvovirus B19 replication in erythroid progenitor cells Fulltext Access 8 Pages 2017
Corrector VX-809 promotes interactions between cytoplasmic loop one and the first nucleotide-binding domain of CFTR Fulltext Access 8 Pages 2017
Human carbonyl reductase 1 participating in intestinal first-pass drug metabolism is inhibited by fatty acids and acyl-CoAs Fulltext Access 8 Pages 2017
Long-term pre-treatment of antioxidant Ginkgo biloba extract EGb-761 attenuates cerebral-ischemia-induced neuronal damage in aged mice Fulltext Access 8 Pages 2017
3D intestinal organoids in metabolic research: virtual reality in a dish Fulltext Access 8 Pages 2017
Determinants of Treatment Eligibility in Veterans With Hepatitis C Viral Infection Fulltext Access 8 Pages 2017
An In-home Advanced Robotic System to Manage Elderly Home-care Patients' Medications: A Pilot Safety and Usability Study Fulltext Access 8 Pages 2017
International Normalized Ratio Is Significantly Elevated With Rivaroxaban and Apixaban Drug Therapies: A Retrospective Study Fulltext Access 8 Pages 2017
Eupafolin nanoparticle improves acute renal injury induced by LPS through inhibiting ROS and inflammation Fulltext Access 8 Pages 2017
The role of NMDA receptor and nitric oxide/cyclic guanosine monophosphate pathway in the antidepressant-like effect of dextromethorphan in mice forced swimming test and tail suspension test Fulltext Access 8 Pages 2017
Amelioration of ischemia-reperfusion induced functional and biochemical deficit in mice by Ocimum kilimandscharicum leaf extract Fulltext Access 8 Pages 2017
PGC-1 alpha interacts with microRNA-217 to functionally regulate breast cancer cell proliferation Fulltext Access 8 Pages 2017
Effect of dietary n-3 fatty acids supplementation on fatty acid metabolism in atorvastatin-administered SHR.Cg-Leprcp/NDmcr rats, a metabolic syndrome model Fulltext Access 8 Pages 2017
Rapamycin inhibits the proliferation of endothelial cells in hemangioma by blocking the mTOR-FABP4 pathway Fulltext Access 8 Pages 2017
Long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 regulates the expression of Gli2 by miR-202 to strengthen gastric cancer progression Fulltext Access 8 Pages 2017
Insight into the role of urotensin II-related peptide tyrosine residue in UT activation Fulltext Access 8 Pages 2017
Highly expressed NRSN2 is related to malignant phenotype in ovarian cancer Fulltext Access 8 Pages 2017
MicroRNA138 regulates keratin 17 protein expression to affect HaCaT cell proliferation and apoptosis by targeting hTERT in psoriasis vulgaris Fulltext Access 8 Pages 2017
Adaptogenic herb ginseng (Panax) as medical food: Status quo and future prospects Fulltext Access 8 Pages 2017
The effect of d-galactose induced oxidative stress on in vitro redox homeostasis in rat plasma and erythrocytes Fulltext Access 8 Pages 2017
Ghrelin upregulates PepT1 activity in the small intestine epithelium of rats with sepsis Fulltext Access 8 Pages 2017
Extracellular Clâ-free-induced cardioprotection against hypoxia/reoxygenation is associated with attenuation of mitochondrial permeability transition pore Fulltext Access 8 Pages 2017
Modulation of the lipid profile and insulin levels of streptozotocin induced diabetic rats by ethanol extract of Cnidoscolus aconitifolius leaves and some fractions: Effect on the oral glucose tolerance of normoglycemic rats Fulltext Access 8 Pages 2017
Novel transferrin modified and doxorubicin loaded Pluronic 85/lipid-polymeric nanoparticles for the treatment of leukemia: In vitro and in vivo therapeutic effect evaluation Fulltext Access 8 Pages 2017
miR-381 inhibited breast cancer cells proliferation, epithelial-to-mesenchymal transition and metastasis by targeting CXCR4 Fulltext Access 8 Pages 2017
Curcumin inhibits growth potential by G1 cell cycle arrest and induces apoptosis in p53-mutated COLO 320DM human colon adenocarcinoma cells Fulltext Access 8 Pages 2017
miR-375 ameliorates sepsis by downregulating miR-21 level via inhibiting JAK2-STAT3 signaling Fulltext Access 8 Pages 2017