Trans-4-methoxy-β-nitrostyrene relaxes rat thoracic aorta through a sGC-dependent pathway Fulltext Access 8 Pages 2017
Recombinant Newcastle disease virus expressing human TRAIL as a potential candidate for hepatoma therapy Fulltext Access 8 Pages 2017
Chemical inhibitors of c-Met receptor tyrosine kinase stimulate osteoblast differentiation and bone regeneration Fulltext Access 8 Pages 2017
Effects of bilobalide, ginkgolide B and picrotoxinin on GABAA receptor modulation by structurally diverse positive modulators Fulltext Access 8 Pages 2017
Protective effects of fluoroquinolones on UV-induced damage of cultured ocular cell lines Fulltext Access 8 Pages 2017
Chloroquine blocks the Kir4.1 channels by an open-pore blocking mechanism Fulltext Access 8 Pages 2017
The signalling mechanisms of a novel mitochondrial complex I inhibitor prevent lipid accumulation and attenuate TNF-α-induced insulin resistance in vitro Fulltext Access 8 Pages 2017
Inhibition of osteoporosis by the αvβ3 integrin antagonist of rhodostomin variants Fulltext Access 8 Pages 2017
An apple oligogalactan enhances the growth inhibitory effect of 5-fluorouracil on colorectal cancer Fulltext Access 8 Pages 2017
Effect of D-Ala2GIP, a stable GIP receptor agonist on MPTP-induced neuronal impairments in mice Fulltext Access 8 Pages 2017
Licocoumarone isolated from Glycyrrhiza uralensis selectively alters LPS-induced inflammatory responses in RAW 264.7 macrophages Fulltext Access 8 Pages 2017
JTE-852, a novel spleen tyrosine kinase inhibitor, blocks mediator secretion from mast cells with immunoglobulin E crosslinking Fulltext Access 8 Pages 2017
B7-33 replicates the vasoprotective functions of human relaxin-2 (serelaxin) Fulltext Access 8 Pages 2017
Evaluation of the CART peptide expression in morphine sensitization in male rats Fulltext Access 8 Pages 2017
(-)-Terpinen-4-ol changes intracellular Ca2+ handling and induces pacing disturbance in rat hearts Fulltext Access 8 Pages 2017
Muscarinic receptor mediated signaling pathways in hepatocytes from CCL4 - induced liver fibrotic rat Fulltext Access 8 Pages 2017
Antidiabetic, antidyslipidemic and toxicity profile of ENV-2: A potent pyrazole derivative against diabetes and related diseases Fulltext Access 8 Pages 2017
JTP-117968, a novel selective glucocorticoid receptor modulator, exhibits improved transrepression/transactivation dissociation Fulltext Access 8 Pages 2017
Phenylmethimazole and a thiazole derivative of phenylmethimazole inhibit IL-6 expression by triple negative breast cancer cells Fulltext Access 8 Pages 2017
Guggulsterone sensitized drug-resistant human hepatocarcinoma cells to doxorubicin through a Cox-2/P-gp dependent pathway Fulltext Access 8 Pages 2017
Urothelial acetylcholine involvement in ATP-induced contractile responses of the rat urinary bladder Fulltext Access 8 Pages 2017
A brain-targeted ampakine compound protects against opioid-induced respiratory depression Fulltext Access 8 Pages 2017
RP5063, a novel, multimodal, serotonin receptor modulator, prevents monocrotaline-induced pulmonary arterial hypertension in rats Fulltext Access 8 Pages 2017
Topical ocular treatment with monoclonal antibody Fab fragments targeting Japanese cedar pollen Cry j 1 inhibits Japanese cedar pollen-induced allergic conjunctivitis in mice Fulltext Access 8 Pages 2017
Dose Orchestration and System Enhancement (DOSE): A practice model based on the Habituation-Intention Framework Fulltext Access 8 Pages 2017
Pharmacological effects of a recombinant hPTH(1â34) derived peptide on ovariectomized rats Fulltext Access 8 Pages 2017
Cinobufagin induces apoptosis of osteosarcoma cells through inactivation of Notch signaling Fulltext Access 8 Pages 2017
Cardamonin (2â²,4â²-dihydroxy-6â²-methoxychalcone) isolated from Boesenbergia rotunda (L.) Mansf. inhibits CFA-induced rheumatoid arthritis in rats Fulltext Access 8 Pages 2017
Canagliflozin, a sodium glucose cotransporter 2 inhibitor, attenuates obesity-induced inflammation in the nodose ganglion, hypothalamus, and skeletal muscle of mice Fulltext Access 8 Pages 2017
Caffeic acid phenethyl ester attenuates lipopolysaccharide-stimulated proinflammatory responses in human gingival fibroblasts via NF-κB and PI3K/Akt signaling pathway Fulltext Access 8 Pages 2017
In vivo and vitro characterization of the effects of kisspeptin-13, endogenous ligands for GPR54, on mouse gastrointestinal motility Fulltext Access 8 Pages 2017
Decrease of high voltage Ca2+ currents in the dentate gyrus granule cells by entorhinal amyloidopathy is reversed by calcium channel blockade Fulltext Access 8 Pages 2017
Cyclic AMP (cAMP) confers drug resistance against DNA damaging agents via PKAIA in CML cells Fulltext Access 8 Pages 2017
Blockade of patch-based μ opioid receptors in the striatum attenuates methamphetamine-induced conditioned place preference and reduces activation of the patch compartment Fulltext Access 8 Pages 2017
Amitriptyline down-regulates coenzyme Q10 biosynthesis in lung cancer cells Fulltext Access 8 Pages 2017
SIRT2 mediated antitumor effects of shikonin on metastatic colorectal cancer Fulltext Access 8 Pages 2017
Reducing the global burden of HTLV-1 infection: An agenda for research and action Fulltext Access 8 Pages 2017
7-cyclopentyl-5-(4-phenoxyphenyl)â7H-pyrrolo[2,3-d] pyrimidin-4-ylamine inhibits the proliferation and migration of vascular smooth muscle cells by suppressing ERK and Akt pathways Fulltext Access 8 Pages 2017
Involvement of arterial baroreflex and nicotinic acetylcholine receptor α7 subunit pathway in the protection of metformin against stroke in stroke-prone spontaneously hypertensive rats Fulltext Access 8 Pages 2017
Loop-F of the α-subunit determines the pharmacologic profile of novel competitive inhibitors of GABAA receptors Fulltext Access 8 Pages 2017
12-Chloracetyl-PPD, a novel dammarane derivative, shows anti-cancer activity via delay the progression of cell cycle G2/M phase and reactive oxygen species-mediate cell apoptosis Fulltext Access 8 Pages 2017
Involvement of BDNF/TrkB signaling in the effect of diphenyl diselenide on motor function in a Parkinson's disease rat model Fulltext Access 8 Pages 2017
Rhinacanthin-C enhances doxorubicin cytotoxicity via inhibiting the functions of P-glycoprotein and MRP2 in breast cancer cells Fulltext Access 8 Pages 2017
Tetradecanol reduces EL-4 T cell growth by the down regulation of NF-κB mediated IL-2 secretion Fulltext Access 8 Pages 2017
Nebivolol prevents ethanol-induced reactive oxygen species generation and lipoperoxidation in the rat kidney by regulating NADPH oxidase activation and expression Fulltext Access 8 Pages 2017
Inhibition of estrogen related receptor α attenuates vascular smooth muscle cell proliferation and migration by regulating RhoA/p27Kip1 and β-Catenin/Wnt4 signaling pathway Fulltext Access 8 Pages 2017
Inositol hexaphosphate suppresses colorectal cancer cell proliferation via the Akt/GSK-3β/β-catenin signaling cascade in a 1,2-dimethylhydrazine-induced rat model Fulltext Access 8 Pages 2017
The enhancement of TXA2 receptors-mediated contractile response in intrarenal artery dysfunction in type 2 diabetic mice Fulltext Access 8 Pages 2017
Pharmacokinetic based study on “lagged stimulation” of Curcumae Longae Rhizoma - Piper nigrum couplet in their main active components' metabolism using UPLC-MS-MS Fulltext Access 8 Pages 2017
A randomized efficacy trial of a cognitive-behavioral group intervention to prevent Internet Use Disorder onset in adolescents: The PROTECT study protocol Fulltext Access 8 Pages 2017
One and done: Reasons principal investigators conduct only one FDA-regulated drug trial Fulltext Access 8 Pages 2017
Effect of early use of AbobotulinumtoxinA after stroke on spasticity progression: Protocol for a randomised controlled pilot study in adult subjects with moderate to severe upper limb spasticity (ONTIME pilot) Fulltext Access 8 Pages 2017
Metabolic costs of daily activity in older adults (Chores XL) study: Design and methods Fulltext Access 8 Pages 2017
Searching for new biomarkers in ovarian cancer patients: Rationale and design of a retrospective study under the Mermaid III project Fulltext Access 8 Pages 2017
A two-stage design for phase II trials with time-to-event endpoint using restricted follow-up Fulltext Access 8 Pages 2017
Use of a single, independent IRB: Case study of an NIH funded consortium Fulltext Access 8 Pages 2017
A prospective development study of software-guided radio-frequency ablation of primary and secondary liver tumors: Clinical intervention modelling, planning and proof for ablation cancer treatment (ClinicIMPPACT) Fulltext Access 8 Pages 2017
Fargesin exerts anti-inflammatory effects in THP-1 monocytes by suppressing PKC-dependent AP-1 and NF-ĸB signaling Fulltext Access 8 Pages 2017
7, 8-Dihydroxycoumarin (daphnetin) protects INS-1 pancreatic β-cells against streptozotocin-induced apoptosis Fulltext Access 8 Pages 2017
Lindersin B from Lindernia crustacea induces neuritogenesis by activation of tyrosine kinase A/phosphatidylinositol 3 kinase/extracellular signal-regulated kinase signaling pathway Fulltext Access 8 Pages 2017
In vitro and in vivo antimalarial potential of oleoresin obtained from Copaifera reticulata Ducke (Fabaceae) in the Brazilian Amazon rainforest Fulltext Access 8 Pages 2017
Design of a randomized, controlled, comparative-effectiveness trial testing a Family Model of Diabetes Self-Management Education (DSME) vs. Standard DSME for Marshallese in the United States Fulltext Access 8 Pages 2017
Molecular pathways related to the longevity promotion and cognitive improvement of Cistanche tubulosa in Drosophila Fulltext Access 8 Pages 2017
Aloesin from Aloe vera accelerates skin wound healing by modulating MAPK/Rho and Smad signaling pathways in vitro and in vivo Fulltext Access 8 Pages 2017
SOS response in bacteria: Inhibitory activity of lichen secondary metabolites against Escherichia coli RecA protein Fulltext Access 8 Pages 2017
Phenethyl isothiocyanate suppresses cancer stem cell properties in vitro and in a xenograft model Fulltext Access 8 Pages 2017
Galangin ameliorates cisplatin induced nephrotoxicity in vivo by modulation of oxidative stress, apoptosis and inflammation through interplay of MAPK signaling cascade Fulltext Access 8 Pages 2017
Screening of hepatoprotective compounds from licorice against carbon tetrachloride and acetaminophen induced HepG2 cells injury Fulltext Access 8 Pages 2017
Safflower bud inhibits RANKL-induced osteoclast differentiation and prevents bone loss in ovariectomized mice Fulltext Access 8 Pages 2017
Extracts and compounds active on TRP ion channels from Waldheimia glabra, a ritual medicinal plant from Himalaya Fulltext Access 8 Pages 2017
Gramine inhibits angiogenesis and induces apoptosis via modulation of TGF-β signalling in 7,12 dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinoma Fulltext Access 8 Pages 2017
Hepatoprotective effects of Yulangsan flavone against carbon tetrachloride (CCl4)-induced hepatic fibrosis in rats Fulltext Access 8 Pages 2017
Adenoviral-expressed recombinant granulocyte monocyte colony-stimulating factor (GM-CSF) enhances protective immunity induced by inactivated Newcastle Disease Virus (NDV) vaccine Fulltext Access 8 Pages 2017
The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness Fulltext Access 8 Pages 2017
Evaluation of two strains of Marek's disease virus serotype 1 for the development of recombinant vaccines against very virulent infectious bursal disease virus Fulltext Access 8 Pages 2017
Activation of TNF-α-AID axis and co-inhibitory signals in coordination with Th1-type immunity in a mouse model recapitulating hepatitis B Fulltext Access 8 Pages 2017
Therapeutic efficacy of peramivir against H5N1 highly pathogenic avian influenza viruses harboring the neuraminidase H275Y mutation Fulltext Access 8 Pages 2017
Recombinant DNA vaccine of Hantavirus Gn and LAMP1 induced long-term immune protection in mice Fulltext Access 8 Pages 2017
Different routes and doses influence protection in pigs immunised with the naturally attenuated African swine fever virus isolate OURT88/3 Fulltext Access 8 Pages 2017
Uncovering oxysterol-binding protein (OSBP) as a target of the anti-enteroviral compound TTP-8307 Fulltext Access 8 Pages 2017
A screening assay for the identification of host cell requirements and antiviral targets for hepatitis D virus infection Fulltext Access 8 Pages 2017
Antiviral activity of ovine interferon tau 4 against foot-and-mouth disease virus Fulltext Access 8 Pages 2017
Efficacy of novel antibody-based drugs against rhinovirus infection: In vitro and in vivo results Fulltext Access 8 Pages 2017
IL-22 suppresses the infection of porcine enteric coronaviruses and rotavirus by activating STAT3 signal pathway Fulltext Access 8 Pages 2017
Microspheres-prime/rMVA-boost vaccination enhances humoral and cellular immune response in IFNAR(â/â) mice conferring protection against serotypes 1 and 4 of bluetongue virus Fulltext Access 8 Pages 2017
Anti-inflammatory and antiviral activities of cynanversicoside A and cynanversicoside C isolated from Cynanchun paniculatum in influenza A virus-infected mice pulmonary microvascular endothelial cells Fulltext Access 8 Pages 2017
Anti-herpes simplex virus type 1 activity of Houttuynoid A, a flavonoid from Houttuynia cordata Thunb Fulltext Access 8 Pages 2017
APRIL:TACI axis is dispensable for the immune response to rabies vaccination Fulltext Access 8 Pages 2017
Recombinant hemagglutinin proteins formulated in a novel PELC/CpG adjuvant for H7N9 subunit vaccine development Fulltext Access 8 Pages 2017
Characterization of oseltamivir-resistant influenza virus populations in immunosuppressed patients using digital-droplet PCR: Comparison with qPCR and next generation sequencing analysis Fulltext Access 8 Pages 2017
Cinnamic acid derivatives inhibit hepatitis C virus replication via the induction of oxidative stress Fulltext Access 8 Pages 2017
Antiviral activity of gemcitabine against human rhinovirus in vitro and in vivo Fulltext Access 8 Pages 2017
A novel candidate HPV vaccine: MS2 phage VLP displaying a tandem HPV L2 peptide offers similar protection in mice to Gardasil-9 Fulltext Access 8 Pages 2017
Immune efficacy of an adenoviral vector-based swine influenza vaccine against antigenically distinct H1N1 strains in mice Fulltext Access 8 Pages 2017
IFNA2 p.Ala120Thr impairs the inhibitory activity of Interferon-α2 against the hepatitis B virus through altering its binding to the receptor Fulltext Access 8 Pages 2017
Feasibility study design and methods for a home-based, square-stepping exercise program among older adults with multiple sclerosis: The SSE-MS project Fulltext Access 8 Pages 2017
Analyses of drug combinations using missing data shortens trial periods in phase I/II oncology trials Fulltext Access 8 Pages 2017