Multiple pharmacological targets, cytotoxicity, and phytochemical profile of Aphloia theiformis (Vahl.) Benn. Fulltext Access 9 Pages 2017
Spectral characterisation, antiviral activities, in silico ADMET and molecular docking of the compounds isolated from Tectona grandis to chikungunya virus Fulltext Access 9 Pages 2017
Effect of the Egyptian propolis on the hepatic antioxidant defense and pro-apoptotic p53 and anti-apoptotic bcl2 expressions in aflatoxin B1 treated male mice Fulltext Access 9 Pages 2017
Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms Fulltext Access 9 Pages 2017
Capparis spinosa leaves extract: Source of bioantioxidants with nephroprotective and hepatoprotective effects Fulltext Access 9 Pages 2017
Regulation of different components from Ophiopogon japonicus on autophagy in human lung adenocarcinoma A549Cells through PI3K/Akt/mTOR signaling pathway Fulltext Access 9 Pages 2017
Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity Fulltext Access 9 Pages 2017
MiR-30b-5p acts as a tumor suppressor, repressing cell proliferation and cell cycle in human hepatocellular carcinoma Fulltext Access 9 Pages 2017
Paeoniflorin attenuates ANIT-induced cholestasis by inhibiting apoptosis in vivo via mitochondria-dependent pathway Fulltext Access 9 Pages 2017
2-[(4-Chlorobenzyl) amino]-4-methyl-1,3-thiazole-5-carboxylic acid exhibits antidiabetic potential and raises insulin sensitivity via amelioration of oxidative enzymes and inflammatory cytokines in streptozotocinËinduced diabetic rats Fulltext Access 9 Pages 2017
microRNA-23b suppresses epithelial-mesenchymal transition (EMT) and metastasis in hepatocellular carcinoma via targeting Pyk2 Fulltext Access 9 Pages 2017
Dehydrobruceine B enhances the cisplatin-induced cytotoxicity through regulation of the mitochondrial apoptotic pathway in lung cancer A549 cells Fulltext Access 9 Pages 2017
Tamarix gallica phenolics protect IEC-6 cells against H2O2 induced stress by restricting oxidative injuries and MAPKs signaling pathways Fulltext Access 9 Pages 2017
Epoxy clerodane diterpene inhibits MCF-7 human breast cancer cell growth by regulating the expression of the functional apoptotic genes Cdkn2A, Rb1, mdm2 and p53 Fulltext Access 9 Pages 2017
Apigenin attenuates hippocampal oxidative events, inflammation and pathological alterations in rats fed high fat, fructose diet Fulltext Access 9 Pages 2017
HPLC-DAD-QTOF-MS profiling of phenolics from leaf extracts of two Tunisian fig cultivars: Potential as a functional food Fulltext Access 9 Pages 2017
Antiprotozoal, antimycobacterial, and anti-inflammatory evaluation of Cnidoscolus chayamansa (Mc Vaugh) extract and the isolated compounds Fulltext Access 9 Pages 2017
Gastroprotective effect and mechanism of action of Croton rhamnifolioides essential oil in mice Fulltext Access 9 Pages 2017
Acetyl-l-carnitine protects dopaminergic nigrostriatal pathway in 6-hydroxydopamine-induced model of Parkinson's disease in the rat Fulltext Access 9 Pages 2017
URB597 reduces biochemical, behavioral and morphological alterations in two neurotoxic models in rats Fulltext Access 9 Pages 2017
Hepatoprotective role of Ricinus communis leaf extract against d-galactosamine induced acute hepatitis in albino rats Fulltext Access 9 Pages 2017
HCRP1 downregulation promotes hepatocellular carcinoma cell migration and invasion through the induction of EGFR activation and epithelial-mesenchymal transition Fulltext Access 9 Pages 2017
Cinnamaldehyde potentially attenuates gestational hyperglycemia in rats through modulation of PPARγ, proinflammatory cytokines and oxidative stress Fulltext Access 9 Pages 2017
Enhanced effect in combination of curcumin- and ketoconazole-loaded methoxy poly (ethylene glycol)-poly (ε-caprolactone) micelles Fulltext Access 9 Pages 2017
Anti-inflammatory effects of ethanolic extract of Rosmarinus officinalis L. and rosmarinic acid in a rat model of neuropathic pain Fulltext Access 9 Pages 2017
Txn1, Ctsd and Cdk4 are key proteins of combination therapy with taurine, epigallocatechin gallate and genistein against liver fibrosis in rats Fulltext Access 9 Pages 2017
Protective effects of bilobalide against ethanol-induced gastric ulcer in vivo/vitro Fulltext Access 9 Pages 2017
Inhibition of heat shock protein (Hsp) 90 potentiates the antiproliferative and pro-apoptotic effects of 2-(4â²fluoro-phenylamino)-4H-1,3-thiazine[6,5-b]indole in A2780cis cells Fulltext Access 9 Pages 2017
Cytotoxicity of trans-chalcone and licochalcone A against breast cancer cells is due to apoptosis induction and cell cycle arrest Fulltext Access 9 Pages 2017
Icaritin induces mitochondrial apoptosis by up-regulating miR-124 in human oral squamous cell carcinoma cells Fulltext Access 9 Pages 2017
Nutraceutical inherent of Spinacia oleracea Linn. methanolic leaf extract ameliorates isoproterenol induced myocardial necrosis in male albino Wistar rats via mitigating inflammation Fulltext Access 9 Pages 2017
Targeted osteosarcoma chemotherapy using RGD peptide-installed doxorubicin-loaded biodegradable polymeric micelle Fulltext Access 9 Pages 2017
Protective effect of Nigella sativa oil on cisplatin induced nephrotoxicity and oxidative damage in rat kidney Fulltext Access 9 Pages 2017
AMD3100 combined with triptolide inhibit proliferation, invasion and metastasis and induce apoptosis of human U2OS osteosarcoma cells Fulltext Access 9 Pages 2017
iRhom2 is involved in lipopolysaccharide-induced cardiac injury in vivo and in vitro through regulating inflammation response Fulltext Access 9 Pages 2017
miR-590 accelerates lung adenocarcinoma migration and invasion through directly suppressing functional target OLFM4 Fulltext Access 9 Pages 2017
Cigarette smoke extract induces epithelial-mesenchymal transition of human bladder cancer T24 cells through activation of ERK1/2 pathway Fulltext Access 9 Pages 2017
Therapeutic effects of bach1 siRNA on human breast adenocarcinoma cell line Fulltext Access 9 Pages 2017
Regulatory mechanism of mineral-balanced deep sea water on hypocholesterolemic effects in HepG2 hepatic cells Fulltext Access 9 Pages 2017
The combination of db-cAMP and ChABC with poly(propylene carbonate) microfibers promote axonal regenerative sprouting and functional recovery after spinal cord hemisection injury Fulltext Access 9 Pages 2017
Induction of G2/M phase arrest and apoptosis by a new tetrahydroingenol diterpenoid from Euphorbia erythradenia Bioss. in melanoma cancer cells Fulltext Access 9 Pages 2017
Anti-diabetic effect of the ethyl acetate fraction of Clerodendrum volubile: protocatechuic acid suppresses phagocytic oxidative burst and modulates inflammatory cytokines Fulltext Access 9 Pages 2017
Comparison of the DWI and Gd-EOB-DTPA-enhanced MRI on assessing the hepatic ischemia and reperfusion injury after partial hepatectomy Fulltext Access 9 Pages 2017
13-Ethylberberine reduces HMGB1 release through AMPK activation in LPS-activated RAW264.7 cells and protects endotoxemic mice from organ damage Fulltext Access 9 Pages 2017
Rutin protects endothelial dysfunction by disturbing Nox4 and ROS-sensitive NLRP3 inflammasome Fulltext Access 9 Pages 2017
Regulation of miRNAs by herbal medicine: An emerging field in cancer therapies Fulltext Access 9 Pages 2017
Long non-coding RNA CCAT1 promotes human retinoblastoma SO-RB50 and Y79 cells through negative regulation of miR-218-5p Fulltext Access 9 Pages 2017
Long non-coding RNA UC001kfo promotes hepatocellular carcinoma proliferation and metastasis by targeting α-SMA Fulltext Access 9 Pages 2017
Tumor angiogenesis of SCLC inhibited by decreased expression of FMOD via downregulating angiogenic factors of endothelial cells Fulltext Access 9 Pages 2017
Desalted Salicornia europaea extract attenuated vascular neointima formation by inhibiting the MAPK pathway-mediated migration and proliferation in vascular smooth muscle cells Fulltext Access 9 Pages 2017
In vitro antioxidant and anticataractogenic potential of silver nanoparticles biosynthesized using an ethanolic extract of Tabernaemontana divaricata leaves Fulltext Access 9 Pages 2017
Inhibition of the infectivity and inflammatory response of influenza virus by Arbidol hydrochloride in vitro and in vivo (mice and ferret) Fulltext Access 9 Pages 2017
Caffeic acid phenethyl ester protects the brain against hexavalent chromium toxicity by enhancing endogenous antioxidants and modulating the JAK/STAT signaling pathway Fulltext Access 9 Pages 2017
Total sesquiterpene glycosides from Loquat (Eriobotrya japonica) leaf alleviate high-fat diet induced non-alcoholic fatty liver disease through cytochrome P450 2E1 inhibition Fulltext Access 9 Pages 2017
The enhancement mechanism of wine-processed Radix Scutellaria on NTG-induced migraine rats Fulltext Access 9 Pages 2017
Umbelliferon-α-d-glucopyranosyl-(2I â 1II)-α-Dglucopyranoside ameliorates Diethylnitrosamine induced precancerous lesion development in liver via regulation of inflammation, hyperproliferation and antioxidant at pre-clinical stage Fulltext Access 9 Pages 2017
1H-Tetrazol-5-amine and 1,3-thiazolidin-4-one derivatives containing 3-(trifluoromethyl)phenyl scaffold: Synthesis, cytotoxic and anti-HIV studies Fulltext Access 9 Pages 2017
Anti-inflammatory effects of Shufengjiedu capsule for upper respiratory infection via the ERK pathway Fulltext Access 9 Pages 2017
Bufalin enhances radiosensitivity of glioblastoma by suppressing mitochondrial function and DNA damage repair Fulltext Access 9 Pages 2017
High doses of S-methylcysteine cause hypoxia-induced cardiomyocyte apoptosis accompanied by engulfment of mitochondaria by nucleus Fulltext Access 9 Pages 2017
Role of Pannexin1 channels in the resistance of I-10 testicular cancer cells to cisplatin mediated by ATP/IP3 pathway Fulltext Access 9 Pages 2017
The pivotal role of HIF-1α in lung inflammatory injury induced by septic mesenteric lymph Fulltext Access 9 Pages 2017
Autophagy as a potential therapeutic target during epithelial to mesenchymal transition in renal cell carcinoma: An in vitro study Fulltext Access 9 Pages 2017
Renin-angiotensin-aldosterone (RAAS): The ubiquitous system for homeostasis and pathologies Fulltext Access 9 Pages 2017
Neuroprotective properties of anthocyanidin glycosides against H2O2-induced glial cell death are modulated by their different stability and antioxidant activity in vitro Fulltext Access 9 Pages 2017
Hepatoprotective effect of Opuntia microdasys (Lehm.) Pfeiff flowers against diabetes type II induced in rats Fulltext Access 9 Pages 2017
Diallyl trisulfide induces apoptosis and mitotic arrest in AGS human gastric carcinoma cells through reactive oxygen species-mediated activation of AMP-activated protein kinase Fulltext Access 9 Pages 2017
Icaritin induces MC3T3-E1 subclone14 cell differentiation through estrogen receptor-mediated ERK1/2 and p38 signaling activation Fulltext Access 9 Pages 2017
α-Mangostin inhibits DMBA/TPA-induced skin cancer through inhibiting inflammation and promoting autophagy and apoptosis by regulating PI3K/Akt/mTOR signaling pathway in mice Fulltext Access 9 Pages 2017
MicroRNA-505 predicts prognosis and acts as tumor inhibitor in cervical carcinoma with inverse association with FZD4 Fulltext Access 9 Pages 2017
Lutein mitigates cyclophosphamide induced lung and liver injury via NF-κB/MAPK dependent mechanism Fulltext Access 9 Pages 2017
Antiangiogenic activity of PLGA-Lupeol implants for potential intravitreal applications Fulltext Access 9 Pages 2017
Betulinic acid derivative B10 inhibits glioma cell proliferation through suppression of SIRT1, acetylation of FOXO3a and upregulation of Bim/PUMA Fulltext Access 9 Pages 2017
MiR-370 functions as oncogene in melanoma by direct targeting pyruvate dehydrogenase B Fulltext Access 9 Pages 2017
Medicinal plants and their isolated compounds showing anti-Trichomonas vaginalis- activity Fulltext Access 9 Pages 2017
Receptor tyrosine kinase-like orphan receptor 1 (ROR-1): An emerging target for diagnosis and therapy of chronic lymphocytic leukemia Fulltext Access 9 Pages 2017
Cortex Mori Radicis extract attenuates myocardial damages in diabetic rats by regulating ERS Fulltext Access 9 Pages 2017
Baicalein increases cisplatin sensitivity of A549 lung adenocarcinoma cells via PI3K/Akt/NF-κB pathway Fulltext Access 9 Pages 2017
Long non-coding RNA SNHG1 regulates zinc finger E-box binding homeobox 1 expression by interacting with TAp63 and promotes cell metastasis and invasion in Lung squamous cell carcinoma Fulltext Access 9 Pages 2017
The effect of hesperidin and quercetin on oxidative stress, NF-κB and SIRT1 levels in a STZ-induced experimental diabetes model Fulltext Access 9 Pages 2017
Chikusetsu (CHI) triggers mitochondria-regulated apoptosis in human prostate cancer via reactive oxygen species (ROS) production Fulltext Access 9 Pages 2017
Metapristone suppresses non-small cell lung cancer proliferation and metastasis via modulating RAS/RAF/MEK/MAPK signaling pathway Fulltext Access 9 Pages 2017
Anti-steatotic and anti-inflammatory effects of Hovenia dulcis Thunb. extracts in chronic alcohol-fed rats Fulltext Access 9 Pages 2017
Mechanistic insights into the effects of quercetin and/or GLP-1 analogue liraglutide on high-fat diet/streptozotocin-induced type 2 diabetes in rats Fulltext Access 9 Pages 2017
Anti-coagulative and gastrointestinal motility regulative activities of Fructus Aurantii Immaturus and its effective fractions Fulltext Access 9 Pages 2017
Cardioprotective effects of calcitonin gene-related peptide in isolated rat heart and in H9c2 cells via redox signaling Fulltext Access 9 Pages 2017
Cimicifugamide from Cimicifuga rhizomes functions as a nonselective β-AR agonist for cardiac and sudorific effects Fulltext Access 9 Pages 2017
Linc00152 promotes cancer progression in hepatitis B virus-associated hepatocellular carcinoma Fulltext Access 9 Pages 2017
Discovery of new dual PPARγ-GPR40 agonists with robust antidiabetic activity: Design, synthesis and in combo drug evaluation Fulltext Access 9 Pages 2017
MiR-330 inhibits IL-22-induced keratinocyte proliferation through targeting CTNNB1 Fulltext Access 9 Pages 2017
Anti-hyperalgesic effect of Lippia grata leaf essential oil complexed with β-cyclodextrin in a chronic musculoskeletal pain animal model: Complemented with a molecular docking and antioxidant screening Fulltext Access 9 Pages 2017
The protective effect of propofol against TNF-α-induced apoptosis was mediated via inhibiting iNOS/NO production and maintaining intracellular Ca2+ homeostasis in mouse hippocampal HT22 cells Fulltext Access 9 Pages 2017
Ameliorative effect of vitamin E and selenium against oxidative stress induced by sodium azide in liver, kidney, testis and heart of male mice Fulltext Access 9 Pages 2017
Icariin stimulates osteogenic differentiation of rat bone marrow stromal stem cells by increasing TAZ expression Fulltext Access 9 Pages 2017
MiR-376c-3p regulates the proliferation, invasion, migration, cell cycle and apoptosis of human oral squamous cancer cells by suppressing HOXB7 Fulltext Access 9 Pages 2017