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Pharmacology Research Articles

Localized inhibition of P2X7R at the spinal cord injury site improves neurogenic bladder dysfunction by decreasing urothelial P2X3R expression in rats
Fulltext Access 8 Pages 2017
Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1
Fulltext Access 8 Pages 2017
Outer membrane vesicles extracted from Neisseria meningitidis serogroup X for prevention of meningococcal disease in Africa
Fulltext Access 8 Pages 2017
Transient receptor potential TRPM3 channels: Pharmacology, signaling, and biological functions
Fulltext Access 8 Pages 2017
Influence of MDR1 and CYP3A5 genetic polymorphisms on trough levels and therapeutic response of imatinib in newly diagnosed patients with chronic myeloid leukemia
Fulltext Access 8 Pages 2017
Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-gp/ABCB1) transport afatinib and restrict its oral availability and brain accumulation
Fulltext Access 8 Pages 2017
Interstitial lung disease induced by fluoxetine: Systematic review of literature and analysis of Vigiaccess, Eudravigilance and a national pharmacovigilance database
Fulltext Access 8 Pages 2017
Edited course of biomedical research: leaping forward with CRISPR
Fulltext Access 8 Pages 2017
14-3-3 adaptor protein-protein interactions as therapeutic targets for CNS diseases
Fulltext Access 8 Pages 2017
Elettaria cardamomum seed mediated rapid synthesis of gold nanoparticles and its biological activities
Fulltext Access 8 Pages 2017
Ginsenoside Rd promotes non-amyloidogenic pathway of amyloid precursor protein processing by regulating phosphorylation of estrogen receptor alpha
Fulltext Access 8 Pages 2017
3′-Hydroxy-4′-methoxy-β-methyl-β-nitrostyrene inhibits tumor growth through ROS generation and GSH depletion in lung cancer cells
Fulltext Access 8 Pages 2017
Inhibition of collagen synthesis by IWR-1 in normal and keloid-derived skin fibroblasts
Fulltext Access 8 Pages 2017
Acid-sensing ion channel 1a is required for mGlu receptor dependent long-term depression in the hippocampus
Fulltext Access 8 Pages 2017
Expression of ER-α and ER-β during peri-implantation period in uterus is essential for implantation and decidualization in golden hamster
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SIRT1 regulates lipopolysaccharide-induced CD40 expression in renal medullary collecting duct cells by suppressing the TLR4-NF-κB signaling pathway
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Astrocyte contributes to pain development via MMP2-JNK1/2 signaling in a mouse model of complex regional pain syndrome
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Epigallocatechin-3-gallate alleviates paraquat-induced acute lung injury and inhibits upregulation of toll-like receptors
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TNF-α and cancer cachexia: Molecular insights and clinical implications
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LOX-1 promotes right ventricular hypertrophy in hypoxia-exposed rats
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Vitamin B2 deficiency enhances the pro-inflammatory activity of adipocyte, consequences for insulin resistance and metabolic syndrome development
Fulltext Access 8 Pages 2017
SIRT3 mediates decrease of oxidative damage and prevention of ageing in porcine fetal fibroblasts
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Synthetic matrix of polyether-polyurethane as a biological platform for pancreatic regeneration
Fulltext Access 8 Pages 2017
Construction of vascularized pacemaker tissues by seeding cardiac progenitor cells and endothelial progenitor cells into Matrigel
Fulltext Access 8 Pages 2017
Nerve growth factor-carbon nanotube complex exerts prolonged protective effects in an in vitro model of ischemic stroke
Fulltext Access 8 Pages 2017
Transgenerational impairment of hippocampal Akt-mTOR signaling and behavioral deficits in the offspring of mice that experience postpartum depression-like illness
Fulltext Access 8 Pages 2017
MicroRNA-126 suppresses inflammation in endothelial cells under hyperglycemic condition by targeting HMGB1
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Propofol inhibits high glucose-induced PP2A expression in human umbilical vein endothelial cells
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A 6-alkylsalicylate histone acetyltransferase inhibitor inhibits histone acetylation and pro-inflammatory gene expression in murine precision-cut lung slices
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Involvement of epithelial-mesenchymal transition afforded by activation of LOX-1/ TGF-β1/KLF6 signaling pathway in diabetic pulmonary fibrosis
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Tofacitinib ameliorates inflammation in a rat model of airway neutrophilia induced by inhaled LPS
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Pharmacokinetics of tiotropium administered by Respimat® in asthma patients: Analysis of pooled data from Phase II and III clinical trials
Fulltext Access 8 Pages 2017
Fast onset of action of glycopyrronium compared with tiotropium in patients with moderate to severe COPD - A randomised, multicentre, crossover trial
Fulltext Access 8 Pages 2017
Ferulic acid supresses Th2 immune response and prevents remodeling in ovalbumin-induced pulmonary allergy associated with inhibition of epithelial-derived cytokines
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Functional EEG network analysis in schizophrenia: Evidence of larger segregation and deficit of modulation
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Threat distractor and perceptual load modulate test-retest reliability of anterior cingulate cortex response
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Glutamate in dorsolateral prefrontal cortex and auditory verbal hallucinations in patients with schizophrenia: A 1H MRS study
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Association of norepinephrine transporter gene polymorphisms in attention-deficit/hyperactivity disorder in Korean population
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Nicotinamide induces mitochondrial-mediated apoptosis through oxidative stress in human cervical cancer HeLa cells
Fulltext Access 8 Pages 2017
HBK-14 and HBK-15, triple 5-HT1A, 5-HT7 and 5-HT3 antagonists with potent antidepressant- and anxiolytic-like properties, increase seizure threshold in various seizure tests in mice
Fulltext Access 8 Pages 2017
Cigarette smoking and schizophrenia: a specific clinical and therapeutic profile? Results from the FACE-Schizophrenia cohort
Fulltext Access 8 Pages 2017
Toll-like receptors, NF-κB, and IL-27 mediate adenosine A2A receptor signaling in BTBR T+ Itpr3tf/J mice
Fulltext Access 8 Pages 2017
Tetrahydrocannabinol (THC) impairs encoding but not retrieval of verbal information
Fulltext Access 8 Pages 2017
Critical role of CA1 muscarinic receptors on memory acquisition deficit induced by total (TSD) and REM sleep deprivation (RSD)
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Further replication of the synergistic interaction between LPHN3 and the NTAD gene cluster on ADHD and its clinical course throughout adulthood
Fulltext Access 8 Pages 2017
Effects of aripiprazole versus risperidone on brain activation during planning and social-emotional evaluation in schizophrenia: A single-blind randomized exploratory study
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Opiate exposure state controls dopamine D3 receptor and cdk5/calcineurin signaling in the basolateral amygdala during reward and withdrawal aversion memory formation
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Theranostic of biopharmaceuticals
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Therapeutic strategies and mechanisms of drug resistance in anaplastic lymphoma kinase (ALK)-rearranged lung cancer
Fulltext Access 8 Pages 2017
PKCβII-mediated cross-talk of TRPV1/CB2 modulates the glucocorticoid-induced osteoclast overactivity
Fulltext Access 8 Pages 2017
Anti-photoaging potential of propolis extract in UVB-irradiated human dermal fibroblasts through increasing the expression of FOXO3A and NGF genes
Fulltext Access 8 Pages 2017
Isolation and characterization of a bacteriophage and its utilization against multi-drug resistant Pseudomonas aeruginosa-2995
Fulltext Access 8 Pages 2017
Down-regulation of miR-605 promotes the proliferation and invasion of prostate cancer cells by up-regulating EN2
Fulltext Access 8 Pages 2017
Knockdown of HIF-1α inhibits the proliferation and migration of outer root sheath cells exposed to hypoxia in vitro: An involvement of Shh pathway
Fulltext Access 8 Pages 2017
Epigallocatechin-3-gallate reduces the proliferation of benign prostatic hyperplasia cells via regulation of focal adhesions
Fulltext Access 8 Pages 2017
High-content image analysis (HCIA) assay has the highest correlation with direct counting cell suspension compared to the ATP, WST-8 and Alamar blue assays for measurement of cytotoxicity
Fulltext Access 8 Pages 2017
Beyond the PGY-1 community pharmacy residency: Characterizing career pathways of residency graduates
Fulltext Access 8 Pages 2017
No filter: A characterization of #pharmacist posts on Instagram
Fulltext Access 8 Pages 2017
Pharmacy services after a tank car derailment and toxic chemical release in Blount County, Tennessee
Fulltext Access 8 Pages 2017
Low-health literacy flashcards & mobile video reinforcement to improve medication adherence in patients on oral diabetes, heart failure, and hypertension medications
Fulltext Access 8 Pages 2017
Comparison of community and hospital pharmacists' attitudes and behaviors on medication error disclosure to the patient: A pilot study
Fulltext Access 8 Pages 2017
Pharmacists performing hepatitis C antibody point-of-care screening in a community pharmacy: A pilot project
Fulltext Access 8 Pages 2017
Inhibition of EGF-induced migration and invasion by sulfated polysaccharide of Sepiella maindroni ink via the suppression of EGFR/Akt/p38 MAPK/MMP-2 signaling pathway in KB cells
Fulltext Access 8 Pages 2017
Role of NADPHox/Rho-kinase signaling in the cyclosporine-NSAIDs interactions on blood pressure and baroreflexes in female rats
Fulltext Access 8 Pages 2017
Antimicrobial peptides (AMPs): The quintessential 'offense and defense' molecules are more than antimicrobials
Fulltext Access 8 Pages 2017
Original articleLong-term treatment with chaethomellic acid A reduces glomerulosclerosis and arteriolosclerosis in a rat model of chronic kidney disease
Fulltext Access 8 Pages 2017
Long non-coding RNA OR3A4 promotes proliferation and migration in breast cancer
Fulltext Access 8 Pages 2017
Mitochondrial dysfunction is responsible for fatty acid synthase inhibition-induced apoptosis in breast cancer cells by PdpaMn
Fulltext Access 8 Pages 2017
Anxiolytic effect of fatty acids and terpenes fraction from Aloysia triphylla: Serotoninergic, GABAergic and glutamatergic implications
Fulltext Access 8 Pages 2017
Parkia speciosa empty pod prevents hypertension and cardiac damage in rats given N(G)-nitro-l-arginine methyl ester
Fulltext Access 8 Pages 2017
lncRNAs HIF1A-AS2 facilitates the up-regulation of HIF-1α by sponging to miR-153-3p, whereby promoting angiogenesis in HUVECs in hypoxia
Fulltext Access 8 Pages 2017
Original articleComparative effects of schisandrin A, B, and C on Propionibacterium acnes-induced, NLRP3 inflammasome activation-mediated IL-1β secretion and pyroptosis
Fulltext Access 8 Pages 2017
Phosphatidylinositol-3-kinase and protein kinase C are involved in the pro-cognitive and anti-anxiety effects of phytohormone abscisic acid in rats
Fulltext Access 8 Pages 2017
The role of CIP2A in cancer: A review and update
Fulltext Access 8 Pages 2017
MiR-146a functions as a small silent player in gastric cancer
Fulltext Access 8 Pages 2017
Chemotherapeutics-resistance “arms” race: An update on mechanisms involved in resistance limiting EGFR inhibitors in lung cancer
Fulltext Access 8 Pages 2017
Gallic acid increases atrial natriuretic peptide secretion and mechanical dynamics through activation of PKC
Fulltext Access 8 Pages 2017
The Kv1.3 channel blocker Vm24 enhances muscle glucose transporter 4 mobilization but does not reduce body-weight gain in diet-induced obese male rats
Fulltext Access 8 Pages 2017
Crocetin restores diabetic endothelial progenitor cell dysfunction by enhancing NO bioavailability via regulation of PI3K/AKT-eNOS and ROS pathways
Fulltext Access 8 Pages 2017
The in vitro and in vivo effects of microRNA-133a on intervertebral disc destruction by targeting MMP9 in spinal tuberculosis
Fulltext Access 8 Pages 2017
MiR-598: A tumor suppressor with biomarker significance in osteosarcoma
Fulltext Access 8 Pages 2017
Postsynaptic N-type or P/Q-type calcium channels mediate long-term potentiation by group I metabotropic glutamate receptors in the trigeminal oralis
Fulltext Access 8 Pages 2017
PPARγ agonists: Potential treatments for exudative age-related macular degeneration
Fulltext Access 8 Pages 2017
miR-34a knockout attenuates cognitive deficits in APP/PS1 mice through inhibition of the amyloidogenic processing of APP
Fulltext Access 8 Pages 2017
Nkx2.5 enhances the efficacy of mesenchymal stem cells transplantation in treatment heart failure in rats
Fulltext Access 8 Pages 2017
A longevity study with enhancer substances (selegiline, BPAP) detected an unknown tumor-manifestation-suppressing regulation in rat brain
Fulltext Access 8 Pages 2017
Discovery of a novel pan-RAF inhibitor with potent anti-tumor activity in preclinical models of BRAFV600E mutant cancer
Fulltext Access 8 Pages 2017
LIM kinase function and renal growth: Potential role for LIM kinases in fetal programming of kidney development
Fulltext Access 8 Pages 2017
TCV−116, a newly developed angiotensin II receptor antagonist, induces regression of cardiac hypertrophy through suppression of the tissue renin-angiotensin system in spontaneously hypertensive rats
Fulltext Access 8 Pages 2017
Naringin attenuates thioacetamide-induced liver fibrosis in rats through modulation of the PI3K/Akt pathway
Fulltext Access 8 Pages 2017
Neuropathic pain attenuates ischemia reperfusion injury through β2-adrenergic pathway
Fulltext Access 8 Pages 2017
Inhibition of the TGF-β1/Smad signaling pathway protects against cartilage injury and osteoarthritis in a rat model
Fulltext Access 8 Pages 2017
Edaravone ameliorates compression-induced damage in rat nucleus pulposus cells
Fulltext Access 8 Pages 2017
Phrenic and hypoglossal nerve activity during respiratory response to hypoxia in 6-OHDA unilateral model of Parkinson's disease
Fulltext Access 8 Pages 2017
Minocycline restores cognitive-relative altered proteins in young bile duct-ligated rat prefrontal cortex
Fulltext Access 8 Pages 2017
microRNA-1228⁎ impairs the pro-angiogenic activity of gastric cancer cells by targeting macrophage migration inhibitory factor
Fulltext Access 8 Pages 2017
Role of fractalkine/CX3CR1 signaling pathway in the recovery of neurological function after early ischemic stroke in a rat model
Fulltext Access 8 Pages 2017
Enhanced expression of tumour suppressor RAR-β by DSPC nano-formulated lipo-ATRA in the lung of B16F10 cell-implanted C57BL6 mice and in A549 cells
Fulltext Access 8 Pages 2017
Endothelial to mesenchymal transition in the cardiovascular system
Fulltext Access 8 Pages 2017
Celecoxib-induced inhibition of neurogenesis in fetal frontal cortex is attenuated by curcumin via Wnt/β-catenin pathway
Fulltext Access 8 Pages 2017
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