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Daneshyari Pharmacology Journas Latest Articles

Pharmacology Research Articles

Adipose-derived stem cells ameliorate renal interstitial fibrosis through inhibition of EMT and inflammatory response via TGF-β1 signaling pathway
Fulltext Access 8 Pages 2017
Chloroquine (CQ) exerts anti-breast cancer through modulating microenvironment and inducing apoptosis
Fulltext Access 8 Pages 2017
Oral administration with diosgenin enhances the induction of intestinal T helper 1-like regulatory T cells in a murine model of food allergy
Fulltext Access 8 Pages 2017
Procyanidin, a kind of biological flavonoid, induces protective anti-tumor immunity and protects mice from lethal B16F10 challenge
Fulltext Access 8 Pages 2017
Effects of 1,25-dihydroxyvitamin D3 in an ovalbumin-induced allergic rhinitis model
Fulltext Access 8 Pages 2017
Inhibitory effects of quercetin on the progression of liver fibrosis through the regulation of NF-кB/IкBα, p38 MAPK, and Bcl-2/Bax signaling
Fulltext Access 8 Pages 2017
Notoginsenoside R1 suppresses wear particle-induced osteolysis and RANKL mediated osteoclastogenesis in vivo and in vitro
Fulltext Access 8 Pages 2017
IDO1: An important immunotherapy target in cancer treatment
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Cordycepin negatively modulates lipopolysaccharide-induced cytokine production by up-regulation of heme oxygenase-1
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Mesenchymal stem cells upregulate Treg cells via sHLA-G in SLE patients
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Formula PSORI-CM01 inhibits the inflammatory cytokine and chemokine release in keratinocytes via NF-κB expression
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Phytosterols isolated from Clinacanthus nutans induce immunosuppressive activity in murine cells
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Role of central opioid on the antinociceptive effect of sulfated polysaccharide from the red seaweed Solieria filiformis in induced temporomandibular joint pain
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Anti-cancer effect of lactic acid bacteria expressing antioxidant enzymes or IL-10 in a colorectal cancer mouse model
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Chlorogenic acid ameliorated concanavalin A-induced hepatitis by suppression of Toll-like receptor 4 signaling in mice
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The expression and function of the neonatal Fc receptor in thyrocytes of Hashimoto's thyroiditis
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Ampelopsin attenuates lipopolysaccharide-induced inflammatory response through the inhibition of the NF-κB and JAK2/STAT3 signaling pathways in microglia
Fulltext Access 8 Pages 2017
Aspergillus fumigatus-induced early inflammatory response in pulmonary microvascular endothelial cells: Role of p38 MAPK and inhibition by silibinin
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Anti-inflammatory effects of ursolic acid-3-acetate on human synovial fibroblasts and a murine model of rheumatoid arthritis
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Capsular specific IgM enhances complement-mediated phagocytosis and killing of Cryptococcus neoformans by methamphetamine-treated J774.16 macrophage-like cells
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Heterotrimeric complex of p38 MAPK, PKCδ, and TIRAP is required for AP1 mediated inflammatory response
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Immunostimulatory activity of plumieride an iridoid in augmenting immune system by targeting Th-1 pathway in balb/c mice
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Enhanced sublingual immunotherapy by TAT-fused recombinant allergen in a murine rhinitis model
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Quercetin ameliorates imiquimod-induced psoriasis-like skin inflammation in mice via the NF-κB pathway
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Stachydrine ameliorates isoproterenol-induced cardiac hypertrophy and fibrosis by suppressing inflammation and oxidative stress through inhibiting NF-κB and JAK/STAT signaling pathways in rats
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4-Methoxylonchocarpin attenuates inflammation by inhibiting lipopolysaccharide binding to Toll-like receptor of macrophages and M1 macrophage polarization
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Involvement of nitrergic system in anticonvulsant effect of zolpidem in lithium-pilocarpine induced status epilepticus: Evaluation of iNOS and COX-2 genes expression
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Ketamine and aminoguanidine differentially affect Bdnf and Mtor gene expression in the prefrontal cortex of adult male rats
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Protective effect of cinnamaldehyde against glutamate-induced oxidative stress and apoptosis in PC12 cells
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Dose-dependent S-allyl cysteine ameliorates multiple sclerosis disease-related pathology by reducing oxidative stress and biomarkers of dysbiosis in experimental autoimmune encephalomyelitis
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N-(2-methoxyphenyl) benzenesulfonamide, a novel regulator of neuronal G protein-gated inward rectifier K+ channels
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Oridonin induces G2/M cell cycle arrest and apoptosis in human oral squamous cell carcinoma
Fulltext Access 8 Pages 2017
A549 cells as a model to study endogenous LPA1 receptor signaling and regulation
Fulltext Access 8 Pages 2017
20(S)-Ginsenoside Rh2 suppresses proliferation and migration of hepatocellular carcinoma cells by targeting EZH2 to regulate CDKN2A-2B gene cluster transcription
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Pharmacological synergism of 2,2-dichloroacetophenone and EGFR-TKi to overcome TKi-induced resistance in NSCLC cells
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Lactobacillus plantarum strain YU from fermented foods activates Th1 and protective immune responses
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Protective effects of morin on lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting TLR4/NF-κB and activating Nrf2/HO-1 signaling pathways
Fulltext Access 8 Pages 2017
Berberine as a chemical and pharmacokinetic marker of the butanol-extracted Food Allergy Herbal Formula-2
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IRG1 increases MHC class I level in macrophages through STAT-TAP1 axis depending on NADPH oxidase mediated reactive oxygen species
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Anti-inflammatory mechanism of ulinastatin: Inhibiting the hyperpermeability of vascular endothelial cells induced by TNF-α via the RhoA/ROCK signal pathway
Fulltext Access 8 Pages 2017
GV1001 immunotherapy ameliorates joint inflammation in a murine model of rheumatoid arthritis by modifying collagen-specific T-cell responses and downregulating antigen-presenting cells
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Radiation-induced decrease of CD8 + dendritic cells contributes to Th1/Th2 shift
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Therapeutic efficacy of a co-blockade of IL-13 and IL-25 on airway inflammation and remodeling in a mouse model of asthma
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Interleukin-23 mediates the pathogenesis of LPS/GalN-induced liver injury in mice
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Enhanced humoral and CD8 + T cell immunity in mice vaccinated by DNA vaccine against human respiratory syncytial virus through targeting the encoded F protein to dendritic cells
Fulltext Access 8 Pages 2017
Th17/Treg imbalance and increased interleukin-21 are associated with liver injury in patients with chronic severe hepatitis B
Fulltext Access 8 Pages 2017
The correlation between inflammatory injury induced by LPS and RAS in EpH4-Ev cells
Fulltext Access 8 Pages 2017
Psoriasis-like inflammation leads to renal dysfunction via upregulation of NADPH oxidases and inducible nitric oxide synthase
Fulltext Access 8 Pages 2017
Astragaloside IV inhibits breast cancer cell invasion by suppressing Vav3 mediated Rac1/MAPK signaling
Fulltext Access 8 Pages 2017
The efficacy and safety comparison between tenofovir and entecavir in treatment of chronic hepatitis B and HBV related cirrhosis: A systematic review and Meta-analysis
Fulltext Access 8 Pages 2017
Chemical constituents from the whole plants of Pilea cavaleriei Levl subsp. cavaleriei
Fulltext Access 8 Pages 2017
Sappanone A inhibits RANKL-induced osteoclastogenesis in BMMs and prevents inflammation-mediated bone loss
Fulltext Access 8 Pages 2017
Dectin-1 is essential for IL-1β production through JNK activation and apoptosis in Aspergillus fumigatus keratitis
Fulltext Access 8 Pages 2017
Immune-enhancing effects of polysaccharides extracted from Lilium lancifolium Thunb
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Berberine suppresses LPS-induced inflammation through modulating Sirt1/NF-κB signaling pathway in RAW264.7 cells
Fulltext Access 8 Pages 2017
Skullcapflavone II attenuates ovalbumin-induced allergic rhinitis through the blocking of Th2 cytokine production and mast cell histamine release
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Prognostic value of tumor PD-L1 expression combined with CD8+ tumor infiltrating lymphocytes in high grade serous ovarian cancer
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New monoterpenoid oxindole alkaloid derivatives from the stems of Uncaria hirsuta Havil. and their cytotoxicity and tandem mass spectrometric fragmentation
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Target regulation of PI3K/Akt/mTOR pathway by cannabidiol in treatment of experimental multiple sclerosis
Fulltext Access 8 Pages 2017
Identification of human UDP-glucuronosyltransferase isoforms involved in the isofraxidin glucuronidation and assessment of the species differences of the reaction
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Phenanthrene derivatives from roots and rhizomes of Asarum heterotropoides var. mandshuricum
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Structurally diverse secondary metabolites from a deep-sea-derived fungus Penicillium chrysogenum SCSIO 41001 and their biological evaluation
Fulltext Access 8 Pages 2017
Chenopodium bonus-henricus L. - A source of hepatoprotective flavonoids
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4(3H)-Quinazolone regulates innate immune signaling upon respiratory syncytial virus infection by moderately inhibiting the RIG-1 pathway in RAW264.7 cell
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Six new sesquiterpenoids from Nardostachys chinensis Batal
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A new cineol derivative, polyphenols and norterpenoids from Saharan myrtle tea (Myrtus nivellei): Isolation, structure determination, quantitative determination and antioxidant activity
Fulltext Access 8 Pages 2017
A novel method for synthesis of α-spinasterol and its antibacterial activities in combination with ceftiofur
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Phenolic glycosides and monoterpenoids from the roots of Euphorbia ebracteolata and their bioactivities
Fulltext Access 8 Pages 2017
Secondary metabolites from endophytic fungus Chaetomium sp. induce colon cancer cell apoptotic death
Fulltext Access 8 Pages 2017
In vitro phase I metabolism of gamabufotalin and arenobufagin: Reveal the effect of substituent group on metabolic stability
Fulltext Access 8 Pages 2017
Isoindolinone-containing meroterpenoids with α-glucosidase inhibitory activity from mushroom Hericium caput-medusae
Fulltext Access 8 Pages 2017
Secondary metabolites from Astragalus karjaginii BORISS and the evaluation of their effects on cytokine release and hemolysis
Fulltext Access 8 Pages 2017
Gram-scale purification of aconitine and identification of lappaconitine in Aconitum karacolicum
Fulltext Access 8 Pages 2017
Neuroinhibitory meroterpenoid compounds from Cordia oncocalyx
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Marine OMEGA-3 fatty acids in the prevention of cardiovascular disease
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Carvedilol can attenuate histamine-induced paw edema and formaldehyde-induced arthritis in rats without risk of gastric irritation
Fulltext Access 8 Pages 2017
Dextran sulphate sodium colitis in C57BL/6J mice is alleviated by Lactococcus lactis and worsened by the neutralization of Tumor necrosis Factor α
Fulltext Access 8 Pages 2017
Comparative effect of berberine and its derivative 8-cetylberberine on attenuating atherosclerosis in ApoE−/− mice
Fulltext Access 8 Pages 2017
Halofuginone inhibits TNF-α-induced the migration and proliferation of fibroblast-like synoviocytes from rheumatoid arthritis patients
Fulltext Access 8 Pages 2017
Ponciretin attenuates ethanol-induced gastric damage in mice by inhibiting inflammatory responses
Fulltext Access 8 Pages 2017
Purinergic P2X7 receptor mediates acetaldehyde-induced hepatic stellate cells activation via PKC-dependent GSK3β pathway
Fulltext Access 8 Pages 2017
CD14++ CD16− monocytes are the main source of 11β-HSD type 1 after IL-4 stimulation
Fulltext Access 8 Pages 2017
Fucoidan inhibits LPS-induced inflammation in vitro and during the acute response in vivo
Fulltext Access 8 Pages 2017
Effect of donor STAT4 polymorphism rs7574865 on clinical outcomes of pediatric acute leukemia patients after hematopoietic stem cell transplant
Fulltext Access 8 Pages 2017
Interleukin-10 inhibits neuroinflammation-mediated apoptosis of ventral mesencephalic neurons via JAK-STAT3 pathway
Fulltext Access 8 Pages 2017
Characterization and evaluation of nanoencapsulated diethylcarbamazine in model of acute hepatic inflammation
Fulltext Access 8 Pages 2017
Crocin modulates IL-4/IL-13 signaling and ameliorates experimentally induced allergic airway asthma in a murine model
Fulltext Access 8 Pages 2017
LncRNA HOTAIR alleviates rheumatoid arthritis by targeting miR-138 and inactivating NF-κB pathway
Fulltext Access 8 Pages 2017
“Click” reaction based synthesis of nimbolide derivatives and study of their insect antifeedant activity against Spodoptera litura Larvae
Fulltext Access 8 Pages 2017
Pentanoic acid induces thymic stromal lymphopoietin production through Gq/11 and Rho-associated protein kinase signaling pathway in keratinocytes
Fulltext Access 8 Pages 2017
Resveratrol alleviates cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasome activation through Sirt1-dependent autophagy induction
Fulltext Access 8 Pages 2017
Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice
Fulltext Access 8 Pages 2017
Direct effects of interleukin-8 on growth and functional activity of T lymphocytes
Fulltext Access 8 Pages 2017
An immunosuppressive function of interleukin-35 in chronic hepatitis C virus infection
Fulltext Access 8 Pages 2017
An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression
Fulltext Access 8 Pages 2017
Aldose reductase inhibitors attenuate β-amyloid-induced TNF-α production in microlgia via ROS-PKC-mediated NF-κB and MAPK pathways
Fulltext Access 8 Pages 2017
Diosgenin glucoside provides neuroprotection by regulating microglial M1 polarization
Fulltext Access 8 Pages 2017
Hyperoside inhibits lipopolysaccharide-induced inflammatory responses in microglial cells via p38 and NFκB pathways
Fulltext Access 8 Pages 2017
Involvement of p38 MAPK and ATF-2 signaling pathway in anti-inflammatory effect of a novel compound bis[(5-methyl)2-furyl](4-nitrophenyl)methane on lipopolysaccharide-stimulated macrophages
Fulltext Access 8 Pages 2017
A limited series of synthetic tetrahydroisoquinoline alkaloids reduce inflammatory gene iNOS via inhibition of p-STAT-1 and suppress HMGB1 secretion in LPS-treated mice lung tissue
Fulltext Access 8 Pages 2017
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