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Daneshyari Pharmacology Journas Latest Articles

Pharmacology Research Articles

Impact of hepatic P450-mediated biotransformation on the disposition and respiratory tract toxicity of inhaled naphthalene
Fulltext Access 8 Pages 2017
Low level exposure to inorganic mercury interferes with B cell receptor signaling in transitional type 1 B cells
Fulltext Access 8 Pages 2017
Mdr1a plays a crucial role in regulating the analgesic effect and toxicity of aconitine by altering its pharmacokinetic characteristics
Fulltext Access 8 Pages 2017
Cutaneous exposure to vesicant phosgene oxime: Acute effects on the skin and systemic toxicity
Fulltext Access 8 Pages 2017
Role of CRF1 receptor in post-incisional plasma extravasation and nociceptive responses in mice
Fulltext Access 8 Pages 2017
Species-specific effects of neuregulin-1β (cimaglermin alfa) on glucose handling in animal models and humans with heart failure
Fulltext Access 8 Pages 2017
Inactivation of the orphan nuclear receptor NR4A1 contributes to apoptosis induction by fangchinoline in pancreatic cancer cells
Fulltext Access 8 Pages 2017
Inhibitory effect of trans-caryophyllene (TC) on leukocyte-endothelial attachment
Fulltext Access 8 Pages 2017
Maternal exposure to a mixture of persistent organic pollutants (POPs) affects testis histology, epididymal sperm count and induces sperm DNA fragmentation in mice
Fulltext Access 8 Pages 2017
Substance P promotes hepatic stellate cell proliferation and activation via the TGF-β1/Smad-3 signaling pathway
Fulltext Access 8 Pages 2017
DNA methylation of extracellular matrix remodeling genes in children exposed to arsenic
Fulltext Access 8 Pages 2017
Deficiency of long isoforms of Nfe2l1 sensitizes MIN6 pancreatic β cells to arsenite-induced cytotoxicity
Fulltext Access 8 Pages 2017
Ochratoxin A transport by the human breast cancer resistance protein (BCRP), multidrug resistance protein 2 (MRP2), and organic anion-transporting polypeptides 1A2, 1B1 and 2B1
Fulltext Access 8 Pages 2017
Arsenic activates the expression of 3β-HSD in mouse Leydig cells through repression of histone H3K9 methylation
Fulltext Access 8 Pages 2017
Differential sensitivities of cellular XPA and PARP-1 to arsenite inhibition and zinc rescue
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Perfluorooctanoic acid exposure disturbs glucose metabolism in mouse liver
Fulltext Access 8 Pages 2017
A two-step model of TiO2 nanoparticle toxicity in human liver tissue
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Chronic alcohol consumption regulates the expression of poly immunoglobulin receptor (pIgR) and secretory IgA in the gut
Fulltext Access 8 Pages 2017
Autoimmune potential of perchloroethylene: Role of lipid-derived aldehydes
Fulltext Access 8 Pages 2017
SGLT2-inhibitor and DPP-4 inhibitor improve brain function via attenuating mitochondrial dysfunction, insulin resistance, inflammation, and apoptosis in HFD-induced obese rats
Fulltext Access 8 Pages 2017
Integrative analysis of hepatic microRNA and mRNA to identify potential biological pathways associated with monocrotaline-induced liver injury in mice
Fulltext Access 8 Pages 2017
Total coumarins of Hedyotis diffusa induces apoptosis of myelodysplastic syndrome SKM-1 cells by activation of caspases and inhibition of PI3K/Akt pathway proteins
Fulltext Access 8 Pages 2017
Alibertia edulis (L.C. Rich.) A.C. Rich - A potent diuretic arising from Brazilian indigenous species
Fulltext Access 8 Pages 2017
Total sesquiterpene lactones prepared from Inula helenium L. has potentials in prevention and therapy of rheumatoid arthritis
Fulltext Access 8 Pages 2017
Clinical efficacy of Rong-Yang-Jyh-Gan-Tang on patients with chronic hepatitis C: A double-blinded randomized placebo-controlled crossover study
Fulltext Access 8 Pages 2017
Prostaglandin E2 facilitates neurite outgrowth in a motor neuron-like cell line, NSC-34
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ABC-transporter blockage mediated by xanthotoxin and bergapten is the major pathway for chemosensitization of multidrug-resistant cancer cells
Fulltext Access 8 Pages 2017
Preventive effect of Gardenia jasminoides on HCl/ethanol induced gastric injury in mice
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Establishment of disseminated intravascular coagulation (DIC) model by a single iv administration of Escherichia coli-derived lipopolysaccharide (LPS) to cynomolgus monkeys and evaluation of its pathophysiological status
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Amiodarone reduces depolarization-evoked glutamate release from hippocampual synaptosomes
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Inhibitory effects of pine nodule extract and its component, SJ-2, on acetylcholine-induced catecholamine secretion and synthesis in bovine adrenal medullary cells
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Action of Bacopa monnieri to antagonize cisplatin-induced emesis in Suncus murinus (house musk shrew)
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Effects of hypnotic bromovalerylurea on microglial BV2 cells
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The effects of 2,3-dimercapto-1-propanesulfonic acid (DMPS) and meso-2,3-dimercaptosuccinic acid (DMSA) on the nephrotoxicity in the mouse during repeated cisplatin (CDDP) treatments
Fulltext Access 8 Pages 2017
Chymase inhibitor prevents the development and progression of non-alcoholic steatohepatitis in rats fed a high-fat and high-cholesterol diet
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The iron chelating agent, deferoxamine detoxifies Fe(Salen)-induced cytotoxicity
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DPP-4 inhibition protects human umbilical vein endothelial cells from hypoxia-induced vascular barrier impairment
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Effects of metformin on proliferation and apoptosis of human megakaryoblastic Dami and MEG-01 cells
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Evaluation of herb-drug interaction of a polyherbal Ayurvedic formulation through high throughput cytochrome P450 enzyme inhibition assay
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Arctiin protects against cardiac hypertrophy through inhibiting MAPKs and AKT signaling pathways
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Acacetin protects against cardiac remodeling after myocardial infarction by mediating MAPK and PI3K/Akt signal pathway
Fulltext Access 8 Pages 2017
Butyrate suppresses motility of colorectal cancer cells via deactivating Akt/ERK signaling in histone deacetylase dependent manner
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A 28-day oral toxicology study of an aqueous extract of Polypodium leucotomos (Fernblock®)
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Hepatoprotective effect of methanolic Tanacetum parthenium extract on CCl4-induced liver damage in rats
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Neuropharmacological profile and chemical analysis of fresh rhizome essential oil of Curcuma longa (turmeric) cultivated in Southwest Nigeria
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In vitro biological assessment of Homalium zeylanicum and isolation of lucidenic acid A triterpenoid
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Amelioration of the cyclophosphamide induced genotoxic damage in mice by the ethanolic extract of Equisetum arvense
Fulltext Access 8 Pages 2017
Safety assessment of freeze-dried powdered Cassiae Semen: evaluation of chronic toxicity (26-week) in Sprague-Dawley rats
Fulltext Access 8 Pages 2017
Perfluorooctanoic acid affects endocytosis involving clathrin light chain A and microRNA-133b-3p in mouse testes
Fulltext Access 8 Pages 2017
Assessing interactions of binary mixtures of Penicillium mycotoxins (PMs) by using a bovine macrophage cell line (BoMacs)
Fulltext Access 8 Pages 2017
Effects of Gnaphalium affine D. Don on hyperuricemia and acute gouty arthritis
Fulltext Access 8 Pages 2017
Consumers' acceptance of medicinal herbs: An application of the technology acceptance model (TAM)
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PG2, a botanically derived drug extracted from Astragalus membranaceus, promotes proliferation and immunosuppression of umbilical cord-derived mesenchymal stem cells
Fulltext Access 8 Pages 2017
Suppression of Baeckea frutescens L. and its components on MyD88-dependent NF-κB pathway in MALP-2-stimulated RAW264.7 cells
Fulltext Access 8 Pages 2017
Pulvis Fellis Suis extract attenuates ovalbumin-induced airway inflammation in murine model of asthma
Fulltext Access 8 Pages 2017
Effects of antrosterol from Antrodia camphorata submerged whole broth on lipid homeostasis, antioxidation, alcohol clearance, and anti-inflammation in livers of chronic-alcohol fed mice
Fulltext Access 8 Pages 2017
The vascular protective effects of Anoectochilus roxburghii polysaccharose under high glucose conditions
Fulltext Access 8 Pages 2017
Biochemical and chemical characterization of Cynara cardunculus L. extract and its potential use as co-adjuvant therapy of chronic myeloid leukemia
Fulltext Access 8 Pages 2017
Evaluation of the diuretic activity of the aqueous and 80% methanol extracts of the root of Euclea divinorum Hiern (Ebenaceae) in Sprague Dawley rats
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Pogostone induces autophagy and apoptosis involving PI3K/Akt/mTOR axis in human colorectal carcinoma HCT116 cells
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The therapeutic effects of Periploca forrestii Schltr. Stem extracts on collagen-induced arthritis by inhibiting the activation of Src/NF-κB signaling pathway in rats
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Anti-tumor and chemosensitization effects of Cryptotanshinone extracted from Salvia miltiorrhiza Bge. on ovarian cancer cells in vitro
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Morella serrata (Lam.) Killick stabilizes biomembrane and rejuvenates sexual competence in male Wistar rats
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Oral treatment with essential oil of Hyptis spicigera Lam. (Lamiaceae) reduces acute pain and inflammation in mice: Potential interactions with transient receptor potential (TRP) ion channels
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Protective effect of a phenolic extract containing indoline amides from Portulaca oleracea against cognitive impairment in senescent mice induced by large dose of D-galactose /NaNO2
Fulltext Access 8 Pages 2017
Antifungal activity and cytotoxicity of extracts and triterpenoid saponins obtained from the aerial parts of Anagallis arvensis L.
Fulltext Access 8 Pages 2017
Aqueous extract from leaf of Artocarpus altilis provides cardio-protection from isoproterenol induced myocardial damage in rats: Negative chronotropic and inotropic effects
Fulltext Access 8 Pages 2017
Anemone rivularis inhibits pyruvate dehydrogenase kinase activity and tumor growth
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In vitro anti-diabetic activity of flavonoids and pheophytins from Allophylus cominia Sw . on PTP1B, DPPIV, alpha-glucosidase and alpha-amylase enzymes
Fulltext Access 8 Pages 2017
Regulatory effect of baicalin on the imbalance of Th17/Treg responses in mice with allergic asthma
Fulltext Access 8 Pages 2017
Plasma metabolomics study of the hepatoprotective effect of glycyrrhetinic acid on realgar-induced sub-chronic hepatotoxicity in mice via 1H NMR analysis
Fulltext Access 8 Pages 2017
Water-extracted tubers of Cyperus rotundus L. enhance endometrial receptivity through leukemia inhibitory factor-mediated expression of integrin αVβ3 and αVβ5
Fulltext Access 8 Pages 2017
A standardized extract of the fruit of Hovenia dulcis alleviated alcohol-induced hangover in healthy subjects with heterozygous ALDH2: A randomized, controlled, crossover trial
Fulltext Access 8 Pages 2017
Artemisia argyi attenuates airway inflammation in ovalbumin-induced asthmatic animals
Fulltext Access 8 Pages 2017
Radix Puerariae modulates glutamatergic synaptic architecture and potentiates functional synaptic plasticity in primary hippocampal neurons
Fulltext Access 8 Pages 2017
Anti-inflammatory effect of the Salvia sclarea L. ethanolic extract on lipopolysaccharide-induced periodontitis in rats
Fulltext Access 8 Pages 2017
Pharmacokinetics and comparative metabolic profiling of iridoid enriched fraction of Picrorhiza kurroa - An Ayurvedic Herb
Fulltext Access 8 Pages 2017
Dosha phenotype specific Ayurveda intervention ameliorates asthma symptoms through cytokine modulations: Results of whole system clinical trial
Fulltext Access 8 Pages 2017
Secondary metabolites from Tetracera potatoria stem bark with anti-mycobacterial activity
Fulltext Access 8 Pages 2017
Herb-drug interaction of Andrographis paniculata (Nees) extract and andrographolide on pharmacokinetic and pharmacodynamic of naproxen in rats
Fulltext Access 8 Pages 2017
The depigmenting effect of natural resorcinol type polyphenols Kuwanon O and Sanggenon T from the roots of morus australis
Fulltext Access 8 Pages 2017
Steroidogenic effect of Erxian decoction for relieving menopause via the p-Akt/PKB pathway in vitro and in vivo
Fulltext Access 8 Pages 2017
Analgesic effect of coumarins from Radix angelicae pubescentis is mediated by inflammatory factors and TRPV1 in a spared nerve injury model of neuropathic pain
Fulltext Access 8 Pages 2017
Behavioral effects induced by antitumor cleronade diterpenes from Casearia sylvestris and in silico interactions with neuron receptors
Fulltext Access 8 Pages 2017
New aspects on the hepatoprotective potential associated with the antioxidant, hypocholesterolemic and anti-inflammatory activities of Vernonia condensata Baker
Fulltext Access 8 Pages 2017
Drug-likeness prediction of chemical constituents isolated from Chinese materia medica Ciwujia
Fulltext Access 8 Pages 2017
Anti-inflammatory and antioxidant effect of modified Bazhengsan in a rat model of chronic bacterial prostatitis
Fulltext Access 8 Pages 2017
Aurantiamide acetate from baphicacanthus cusia root exhibits anti-inflammatory and anti-viral effects via inhibition of the NF-κB signaling pathway in Influenza A virus-infected cells
Fulltext Access 8 Pages 2017
Antitumorpharmacological mechanism of the oral liquid of Poriacocos polysaccharide
Fulltext Access 8 Pages 2017
Antiosteoporotic effect of Hemidesmus indicus Linn. on ovariectomised rats
Fulltext Access 8 Pages 2017
Anti-inflammatory, antimycobacterial and genotoxic evaluation of Doliocarpus dentatus
Fulltext Access 8 Pages 2017
Nephroprotective effect of Rudgea viburnoides (Cham.) Benth leaves on gentamicin-induced nephrotoxicity in rats
Fulltext Access 8 Pages 2017
Lithospermum erythrorhizon extract inhibits Der p2-induced inflammatory response through alleviation of thymic stromal lymphopoietin, nuclear factor Kappa B, and inflammasome expression in human bronchial epithelial cells
Fulltext Access 8 Pages 2017
Quassia “biopiracy” case and the Nagoya Protocol: A researcher's perspective
Fulltext Access 8 Pages 2017
Hydroalcoholic extract from Nerium oleander L. (Apocynaceae) elicits arrhythmogenic activity
Fulltext Access 8 Pages 2017
The ethanol extract of Leonurus sibiricus L. induces antioxidant, antinociceptive and topical anti-inflammatory effects
Fulltext Access 8 Pages 2017
The essential oil from the twigs of Cinnamomum cassia Presl inhibits oxytocin-induced uterine contraction in vitro and in vivo
Fulltext Access 8 Pages 2017
Chronic administration of antioxidant resin from Virola oleifera attenuates atherogenesis in LDLr -/- mice
Fulltext Access 8 Pages 2017
Effects of the ethanol extract of black mulberry (Morus nigra L.) fruit on experimental atherosclerosis in rats
Fulltext Access 8 Pages 2017
Hypoglycemic effect of the polyphenols rich extract from Rose rugosa Thunb on high fat diet and STZ induced diabetic rats
Fulltext Access 8 Pages 2017
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