Sweeping of Adsorbed Therapeutic Protein on Prefillable Syringes Promotes Micron Aggregate Generation Fulltext Access 52 Pages 2018
Inhibitory effects of drugs on the metabolic activity of mouse and human aldehyde oxidases and influence on drug-drug interactions Fulltext Access 52 Pages 2018
Evaluating the evidence for non-monotonic dose-response relationships: A systematic literature review and (re-)analysis of in vivo toxicity data in the area of food safety Fulltext Access 52 Pages 2018
Rotenone exerts developmental neurotoxicity in a human brain spheroid model Fulltext Access 52 Pages 2018
Arthropod toxins and their antinociceptive properties: From venoms to painkillers Fulltext Access 52 Pages 2018
Molecular dynamics simulation strategies for designing carbon-nanotube-based targeted drug delivery Fulltext Access 52 Pages 2018
Influence of fisetin combined with hesperidin on chronic mild hyperhomocysteinemia induced cognitive dysfunction and oxidative stress in wistar rats Fulltext Access 52 Pages 2018
Intranasal oxytocin administration promotes emotional contagion and reduces aggression in a mouse model of callousness Fulltext Access 52 Pages 2018
High fructose diet-induced metabolic syndrome: Pathophysiological mechanism and treatment by traditional Chinese medicine Fulltext Access 53 Pages 2018
Effects of Qijian mixture on type 2 diabetes assessed by metabonomics, gut microbiota and network pharmacology Fulltext Access 53 Pages 2018
Characterization of signalling and regulation of common calcitonin receptor splice variants and polymorphisms Fulltext Access 53 Pages 2018
Multiparametric radiomics improve prediction of lymph node metastasis of rectal cancer compared with conventional radiomics Fulltext Access 53 Pages 2018
Concurrent use of Chinese herbal medicine among hormone users and its association with ischemic stroke risk: A population-based study Fulltext Access 53 Pages 2018
Pravastatin improves risk factors but not ischaemic tolerance in obese rats Fulltext Access 53 Pages 2018
Lipid bilayer stress in obesity-linked inflammatory and metabolic disorders Fulltext Access 53 Pages 2018
Endothelial and cardiac progenitor cells for cardiovascular repair: A controversial paradigm in cell therapy Fulltext Access 53 Pages 2018
Palmitoylethanolamide attenuates cocaine-induced behavioral sensitization and conditioned place preference in mice Fulltext Access 54 Pages 2018
Biophysical Properties and Heating-Induced Aggregation of Lysine-Conjugated Antibody-Drug Conjugates Fulltext Access 54 Pages 2018
Drug-drug interactions in the treatment for alcohol use disorders: A comprehensive review Fulltext Access 54 Pages 2018
Add-on therapy with traditional Chinese medicine: An efficacious approach for lipid metabolism disorders Fulltext Access 54 Pages 2018
Amylin in Alzheimer's disease: Pathological peptide or potential treatment? Fulltext Access 54 Pages 2018
Improved Human Pharmacokinetic Prediction of Hepatically Metabolized Drugs With Species-Specific Systemic Clearance Fulltext Access 54 Pages 2018
Systemic inflammatory response syndromes in the era of interventional cardiology Fulltext Access 54 Pages 2018
Glucagon-like peptide-1 mediates effects of oral galactose in streptozotocin-induced rat model of sporadic Alzheimer's disease Fulltext Access 54 Pages 2018
The pathophysiological mechanisms of motivational deficits in Parkinson's disease Fulltext Access 55 Pages 2018
Anti-inflammatory nitro-fatty acids suppress tumor growth by triggering mitochondrial dysfunction and activation of the intrinsic apoptotic pathway in colorectal cancer cells Fulltext Access 55 Pages 2018
Metabotropic glutamate receptor subtype 7 in the dorsal striatum oppositely modulates pain in sham and neuropathic rats Fulltext Access 55 Pages 2018
Proteomic analysis of honokiol-induced cytotoxicity in thyroid cancer cells Fulltext Access 55 Pages 2018
Chronic paroxetine treatment prevents disruption of methamphetamine-sensitive circadian oscillator in a transgenic mouse model of Huntington's disease Fulltext Access 55 Pages 2018
Effects of Histidine-rich glycoprotein on erythrocyte aggregation and hemolysis: Implications for a role under septic conditions Fulltext Access 55 Pages 2018
Nitric oxide donors for prostate and bladder cancers: Current state and challenges Fulltext Access 55 Pages 2018
The sphingosine 1-phosphate receptor modulator fingolimod as a therapeutic agent: Recent findings and new perspectives Fulltext Access 56 Pages 2018
Effect of distress on transient network dynamics and topological equilibrium in phantom sound perception Fulltext Access 56 Pages 2018
Impairing energy metabolism in solid tumors through agents targeting oncogenic signaling pathways Fulltext Access 56 Pages 2018
Design strategies for physical-stimuli-responsive programmable nanotherapeutics Fulltext Access 56 Pages 2018
Operation of mitochondrial machinery in viral infection-induced immune responses Fulltext Access 56 Pages 2018
Phenylpropanoids and Alzheimer's disease: A potential therapeutic platform Fulltext Access 57 Pages 2018
Social cognition and self-other distinctions in neuropsychiatry: Insights from schizophrenia and Tourette syndrome Fulltext Access 57 Pages 2018
Orexin 2 receptor stimulation enhances resilience, while orexin 2 inhibition promotes susceptibility, to social stress, anxiety and depression Fulltext Access 57 Pages 2018
The potential role of the novel hypothalamic neuropeptides nesfatin-1, phoenixin, spexin and kisspeptin in the pathogenesis of anxiety and anorexia nervosa Fulltext Access 57 Pages 2018
Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses Fulltext Access 57 Pages 2018
Connecting Alzheimer's disease to diabetes: Underlying mechanisms and potential therapeutic targets Fulltext Access 57 Pages 2018
Are there differences in lipid peroxidation and immune biomarkers between major depression and bipolar disorder: Effects of melancholia, atypical depression, severity of illness, episode number, suicidal ideation and prior suicide attempts Fulltext Access 57 Pages 2018
Modular cell-based platform for high throughput identification of compounds that inhibit a viral interferon antagonist of choice Fulltext Access 58 Pages 2018
Racing the clock: The role of circadian rhythmicity in addiction across the lifespan Fulltext Access 58 Pages 2018
Genetics update: Monogenetics, polygene disorders and the quest for modifying genes Fulltext Access 58 Pages 2018
Microbiome-mediated bile acid modification: Role in intestinal drug absorption and metabolism Fulltext Access 59 Pages 2018
A neuro-immune, neuro-oxidative and neuro-nitrosative model of prenatal and postpartum depression Fulltext Access 59 Pages 2018
Stage-specific metabolic features of differentiating neurons: Implications for toxicant sensitivity Fulltext Access 59 Pages 2018
Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance - A review Fulltext Access 59 Pages 2018
Ketamine induces hippocampal apoptosis through a mechanism associated with the caspase-1 dependent pyroptosis Fulltext Access 59 Pages 2018
Pharmacological treatments for opiate and alcohol addiction: A historical perspective of the last 50 years Fulltext Access 59 Pages 2018
Evidence that decreased expression of sinusoidal bile acid transporters accounts for the inhibition by rapamycin of bile flow recovery following liver ischemia Fulltext Access 59 Pages 2018
Which place of pharmacological approaches beyond continuous positive airway pressure to treat vascular disease related to obstructive sleep apnea? Fulltext Access 59 Pages 2018
Meta-analysis: Risk of dry mouth with second generation antidepressants Fulltext Access 59 Pages 2018
Statin therapy improved long-term prognosis in patients with major non-cardiac vascular surgeries: a systematic review and meta-analysis Fulltext Access 60 Pages 2018
Deficits in episodic memory and mental time travel in patients with post-traumatic stress disorder Fulltext Access 60 Pages 2018
Evaluation of the dose-response and fate in the lung and pleura of chrysotile-containing brake dust compared to chrysotile or crocidolite asbestos in a 28-day quantitative inhalation toxicology study Fulltext Access 60 Pages 2018
A better approach to in vivo developmental neurotoxicity assessment: Alignment of rodent testing with effects seen in children after neurotoxic exposures Fulltext Access 60 Pages 2018
Design and validation of an ontology-driven animal-free testing strategy for developmental neurotoxicity testing Fulltext Access 60 Pages 2018
Old wines in new bottles: Repurposing opportunities for Parkinson's disease Fulltext Access 60 Pages 2018
Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression Fulltext Access 60 Pages 2018
Artemisinin and its derivatives in treating helminthic infections beyond schistosomiasis Fulltext Access 61 Pages 2018
Protective roles of melatonin against the amyloid-dependent development of Alzheimer's disease: A critical review Fulltext Access 61 Pages 2018
Cytotoxicity of 18 Cameroonian medicinal plants against drug sensitive and multi-factorial drug resistant cancer cells Fulltext Access 61 Pages 2018
Unhealthy gut, unhealthy brain: The role of the intestinal microbiota in neurodegenerative diseases Fulltext Access 62 Pages 2018
An Intercompany Perspective on Biopharmaceutical Drug Product Robustness Studies Fulltext Access 62 Pages 2018
Assessing medicinal plants traditionally used in the Chirang Reserve Forest, Northeast India for antimicrobial activity Fulltext Access 62 Pages 2018
Uses of fluoxetine in nociceptive pain management: A literature overview Fulltext Access 62 Pages 2018
Innovation and trends in the development and approval of antiviral medicines: 1987-2017 and beyond Fulltext Access 63 Pages 2018
Modeling cocaine relapse in rodents: Behavioral considerations and circuit mechanisms Fulltext Access 63 Pages 2018
Prenatal inflammation exposure-programmed cardiovascular diseases and potential prevention Fulltext Access 63 Pages 2018
Age and impulsive behavior in drug addiction: A review of past research and future directions Fulltext Access 63 Pages 2018
Omega-3 polyunsaturated fatty acids as a treatment strategy for nonalcoholic fatty liver disease Fulltext Access 65 Pages 2018
Process Development and Robust Control of Physical Attributes of an Amorphous Drug Substance Fulltext Access 66 Pages 2018
Hydrogen sulfide in the regulation of insulin secretion and insulin sensitivity: Implications for the pathogenesis and treatment of diabetes mellitus Fulltext Access 66 Pages 2018
Prefrontal cortex executive processes affected by stress in health and disease Fulltext Access 66 Pages 2018
Serotonin receptors in depression and anxiety: Insights from animal studies Fulltext Access 67 Pages 2018
The Application of Modeling and Prediction to the Formation and Stability of Amorphous Solid Dispersions Fulltext Access 67 Pages 2018
Cannabis use during pregnancy: Pharmacokinetics and effects on child development Fulltext Access 67 Pages 2018
Predicting Protein-Protein Interactions of Concentrated Antibody Solutions Using Dilute Solution Data and Coarse-Grained Molecular Models Fulltext Access 67 Pages 2018
Stress induced neural reorganization: A conceptual framework linking depression and Alzheimer's disease Fulltext Access 67 Pages 2018
Extracellular vesicles: A new therapeutic strategy for joint conditions Fulltext Access 68 Pages 2018
Mitochondria, telomeres and cell senescence: Implications for lung ageing and disease Fulltext Access 68 Pages 2018
Melatonin improves cardiac and mitochondrial function during doxorubicin-induced cardiotoxicity: A possible role for peroxisome proliferator-activated receptor gamma coactivator 1-alpha and sirtuin activity? Fulltext Access 69 Pages 2018