Reduction of hemorrhagic transformation by PJ34, a poly(ADP-ribose)polymerase inhibitor, after permanent focal cerebral ischemia in mice Fulltext Access 6 Pages 2008
Protective effect of erythropoietin against aristolochic acid-induced apoptosis in renal tubular epithelial cells Fulltext Access 6 Pages 2008
Ablation of primary afferent neurons by neonatal capsaicin treatment reduces the susceptibility of the portal hypertensive gastric mucosa to ethanol-induced injury in cirrhotic rats Fulltext Access 6 Pages 2008
Protective effects of antithrombin on puromycin aminonucleoside nephrosis in rats Fulltext Access 6 Pages 2008
Effect of quercetin, flavonoids and α-tocopherol, an antioxidant vitamin on experimental reflux oesophagitis in rats Fulltext Access 6 Pages 2008
Superoxide anion mediates angiotensin II-induced potentiation of contractile response to sympathetic stimulation Fulltext Access 6 Pages 2008
5-HT2C receptor activation is a common mechanism on proerectile effects of apomorphine, oxytocin and melanotan-II in rats Fulltext Access 6 Pages 2008
Evaluation of COX-1/COX-2 selectivity and potency of a new class of COX-2 inhibitors Fulltext Access 6 Pages 2008
Adenosine receptor agonists attenuate the development of diazepam withdrawal-induced sensitization in mice Fulltext Access 6 Pages 2008
Agomelatine, a melatonin receptor agonist with 5-HT2C receptor antagonist properties, protects the developing murine white matter against excitotoxicity Fulltext Access 6 Pages 2008
Heat stress alters G-protein coupled receptor-mediated function and endothelium-dependent relaxation in rat mesenteric artery Fulltext Access 6 Pages 2008
Polyaspartoyl·l-arginine inhibits platelet aggregation through stimulation of NO release from endothelial cells Fulltext Access 6 Pages 2008
Prostaglandin D2 induces contraction via thromboxane A2 receptor in rat liver myofibroblasts Fulltext Access 6 Pages 2008
Glucocorticoids inhibited airway hyperresponsiveness through downregulation of CPI-17 in bronchial smooth muscle Fulltext Access 6 Pages 2008
Role of voltage-dependent potassium channels and myo-endothelial gap junctions in 4-aminopyridine-induced inhibition of acetylcholine relaxation in rat carotid artery Fulltext Access 6 Pages 2008
Ethanol induces stronger dopamine release in nucleus accumbens (shell) of alcohol-preferring (bibulous) than in alcohol-avoiding (abstainer) rats Fulltext Access 6 Pages 2008
FK1706, a novel non-immunosuppressant neurophilin ligand, ameliorates motor dysfunction following spinal cord injury through its neuroregenerative action Fulltext Access 6 Pages 2008
Validation of a rat in vivo [3H]M100907 binding assay to determine a translatable measure of 5-HT2A receptor occupancy Fulltext Access 6 Pages 2008
Catechin and proanthocyanidin B4 from grape seeds prevent doxorubicin-induced toxicity in cardiomyocytes Fulltext Access 6 Pages 2008
Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCδ phosphorylation Fulltext Access 6 Pages 2008
Myricetin, a naturally occurring flavonoid, prevents 2-deoxy-d-ribose induced dysfunction and oxidative damage in osteoblastic MC3T3-E1 cells Fulltext Access 6 Pages 2008
Increased expression of SOCS3 in monocytes and SOCS1 in lymphocytes correlates with progressive loss of renal function and cardiovascular risk factors in chronic kidney disease Fulltext Access 6 Pages 2008
Secondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthase Fulltext Access 6 Pages 2008
Anti-inflammatory effects of a bioavailable compound, Artepillin C, in Brazilian propolis Fulltext Access 6 Pages 2008
Roles of naofen, a novel WD-repeat-2 protein, in the CCl4-treated livers — A possible relationship to cell proliferation Fulltext Access 6 Pages 2008
Hydrogen peroxide and antioxidizing enzymes involved in modulation of transient facilitatory effects of nicotine on neurogenic contractile responses in rat gastric fundus Fulltext Access 6 Pages 2008
Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome Fulltext Access 6 Pages 2008
Cardiac effects of trace amines: Pharmacological characterization of trace amine-associated receptors Fulltext Access 6 Pages 2008
Mechanisms for metoclopramide-mediated sensitization and haloperidol-induced catalepsy in rats Fulltext Access 6 Pages 2008
Increased marble-burying behavior in ethanol-withdrawal state: Modulation by gonadotropin-releasing hormone agonist Fulltext Access 6 Pages 2008
Morphine–nicotine interaction in conditioned place preference in mice after chronic nicotine exposure Fulltext Access 6 Pages 2008
Antidepressant-like effect of rutin isolated from the ethanolic extract from Schinus molle L. in mice: Evidence for the involvement of the serotonergic and noradrenergic systems Fulltext Access 6 Pages 2008
In-vitro and in-vivo characterization of JNJ-7925476, a novel triple monoamine uptake inhibitor Fulltext Access 6 Pages 2008
Supraspinally-administered agmatine attenuates the development of oral fentanyl self-administration Fulltext Access 6 Pages 2008
Nitric oxide signaling pathway in the anti-convulsant effect of adenosine against pentylenetetrazol-induced seizure threshold in mice Fulltext Access 6 Pages 2008
Activation of cannabinoid CB1 receptors in the dorsolateral periaqueductal gray induces anxiolytic effects in rats submitted to the Vogel conflict test Fulltext Access 6 Pages 2008
GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid Fulltext Access 6 Pages 2008
C101, a novel 4-amino-piperidine derivative selectively blocks N-type calcium channels Fulltext Access 6 Pages 2008
The radical scavenger edaravone counteracts diabetes in multiple low-dose streptozotocin-treated mice Fulltext Access 6 Pages 2008
Rats with chronic post-ischemia pain exhibit an analgesic sensitivity profile similar to human patients with complex regional pain syndrome — type I Fulltext Access 6 Pages 2008
Involvement of central cannabinoid CB2 receptor in reducing mechanical allodynia in a mouse model of neuropathic pain Fulltext Access 6 Pages 2008
The nonadrenergic noncholinergic-mediated relaxation of corpus cavernosum was impaired in chronic lithium-treated rats: Improvement with l-arginine Fulltext Access 6 Pages 2008
Centrally administered N-methyl-d-aspartate evokes the adrenal secretion of noradrenaline and adrenaline by brain thromboxane A2-mediated mechanisms in rats Fulltext Access 6 Pages 2008
Midazolam attenuates the antinociception induced by d-serine or morphine at the supraspinal level in rats Fulltext Access 6 Pages 2008
The homeostasis of iron and suppression of HO-1 involved in the protective effects of nimodipine on neurodegeneration induced by aluminum overloading in mice Fulltext Access 6 Pages 2008
MAGUK proteins: New targets for pharmacological intervention in the glutamatergic synapse Fulltext Access 6 Pages 2008
Inhibition of osteosarcoma-induced thermal hyperalgesia in mice by the orally active dual enkephalinase inhibitor PL37. Potentiation by gabapentin Fulltext Access 6 Pages 2008
Effects of tamoxifen and raloxifene on normal human endometrial cells in an organotypic in vitro model Fulltext Access 6 Pages 2008
pH dependent efflux of methamphetamine derivatives and their reversal through human Caco-2 cell monolayers Fulltext Access 6 Pages 2008
The role of the N-terminal and mid-region residues of substance P in regulating functional selectivity at the tachykinin NK1 receptor Fulltext Access 6 Pages 2008
Treatment with N-tosyl-l-phenylalanine chloromethyl ketone after the onset of collagen-induced arthritis reduces joint erosion and NF-κB activation Fulltext Access 6 Pages 2008
Activation of P2Y receptors by ATP and by its analogue, ADPβS, triggers two calcium signal pathways in the longitudinal muscle of mouse distal colon Fulltext Access 6 Pages 2008
Brain-derived neurotrophic factor enhances histamine-induced airway responses and changes levels of exhaled nitric oxide in guinea pigs in vivo Fulltext Access 6 Pages 2008
κ-Opioid receptor stimulation inhibits augmentation of Ca2+ transient and hypertrophy induced by isoprenaline in neonatal rat ventricular myocytes — Role of CaMKIIδB Fulltext Access 6 Pages 2008
Calbindin-D28K expression induced by glial cell line-derived neurotrophic factor in substantia nigra neurons dependent on PI3K/Akt/NF-κB signaling pathway Fulltext Access 6 Pages 2008
Endocannabinoids as positive or negative factors in hematopoietic cell migration and differentiation Fulltext Access 6 Pages 2008
Decrease in the synthesis and release of calcitonin gene-related peptide in dorsal root ganglia of spontaneously hypertensive rat: Role of nitric oxide synthase inhibitors Fulltext Access 6 Pages 2008
Antinociceptive property of intrathecal and intraperitoneal administration of a novel water-soluble isoindolin-1-one derivative, JM 1232 (−) in rats Fulltext Access 6 Pages 2008
Altered dopamine D2-like receptor binding in rats with behavioral sensitization to quinpirole: effects of pre-treatment with Ro 41-1049 Fulltext Access 6 Pages 2008
Anti-inflammatory and analgesic properties in a rodent model of a (1→3),(1→6)-linked β-glucan isolated from Pleurotus pulmonarius Fulltext Access 6 Pages 2008
Taurine rescues vascular endothelial dysfunction in streptozocin-induced diabetic rats: Correlated with downregulation of LOX-1 and ICAM-1 expression on aortas Fulltext Access 6 Pages 2008
Modulatory effect of acetyl-l-carnitine on amyloid precursor protein metabolism in hippocampal neurons Fulltext Access 6 Pages 2008
Identification of M1 muscarinic receptor subtype in rat stomach using a tissue segment binding method, and the effects of immobilization stress on the muscarinic receptors Fulltext Access 6 Pages 2008
Time-dependent up-regulation of Ca2+ channels in vas deferens of newborn rats fed with breast milk of mothers under treatment with nifedipine Fulltext Access 6 Pages 2008
Effect of agmatine on DAMGO-induced mu-opioid receptor down-regulation and internalization via activation of IRAS, a candidate for imidazoline I1 receptor Fulltext Access 6 Pages 2008
Rebamipide affects the efficiency of colchicine for the herpes simplex virus-induced inflammation in a Behcet's disease mouse model Fulltext Access 6 Pages 2008
Simultaneous measurement of mechanical responses and transepithelial potential difference and resistance, in guinea-pig isolated, perfused trachea using a novel apparatus: Pharmacological characterization Fulltext Access 6 Pages 2008
A low nicotine concentration augments vesicle motion and exocytosis triggered by K+ depolarisation of chromaffin cells Fulltext Access 6 Pages 2008
Tricarbonyldichlororuthenium (II) dimer (CORM2) activates non-selective cation current in human endothelial cells independently of carbon monoxide releasing Fulltext Access 6 Pages 2008
Involvement of reactive oxygen species in urotensin II-induced proliferation of cardiac fibroblasts Fulltext Access 6 Pages 2008
[3H]BMS-599240 — A novel tritiated ligand for the characterization of BACE1 inhibitors Fulltext Access 6 Pages 2008
ASP4000, a novel, selective, dipeptidyl peptidase 4 inhibitor with antihyperglycemic activity Fulltext Access 6 Pages 2008
Human ApoA-I overexpression diminishes LPS-induced systemic inflammation and multiple organ damage in mice Fulltext Access 6 Pages 2008
Comparison of the involvement of protein kinase C in agonist-induced contractions in mouse aorta and corpus cavernosum Fulltext Access 6 Pages 2008
Baseline triglyceride levels and insulin sensitivity are major determinants of the increase of LDL particle size and buoyancy induced by rosuvastatin treatment in patients with primary hyperlipidemia Fulltext Access 6 Pages 2008
Rosiglitazone promotes atherosclerotic plaque stability in fat-fed ApoE-knockout mice Fulltext Access 6 Pages 2008
The dopaminergic system plays a role in the effect of lithium on inhibitory avoidance memory in mice Fulltext Access 6 Pages 2008
Repeated cocaine administration increases N-methyl-d-aspartate NR1 subunit, extracellular signal-regulated kinase and cyclic AMP response element-binding protein phosphorylation and glutamate release in the rat dorsal striatum Fulltext Access 6 Pages 2008
Quercetin antagonism of Bay K 8644 effects on rat tail artery L-type Ca2+ channels Fulltext Access 6 Pages 2008
The mechanisms of propofol-induced block on ion currents in differentiated H9c2 cardiac cells Fulltext Access 6 Pages 2008
Characterization of the brain-specific non-AT1, non-AT2 angiotensin binding site in the mouse Fulltext Access 6 Pages 2008
Ginsenoside Rg1 and Rb1 enhance glutamate exocytosis from rat cortical nerve terminals by affecting vesicle mobilization through the activation of protein kinase C Fulltext Access 6 Pages 2008
H89 (N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide) induces reduction of myosin regulatory light chain phosphorylation and inhibits cell proliferation Fulltext Access 6 Pages 2008
Decreased plasma and cardiac matrix metalloproteinase activities in patients with coronary artery disease and treated with pravastatin Fulltext Access 6 Pages 2008
Nitric oxide involvement in lipid emulsion-induced vascular pain in anesthetized rats Fulltext Access 6 Pages 2008
Importance of a N-terminal aspartate in the internalization of the neuropeptide Y Y2 receptor Fulltext Access 6 Pages 2008
Aripiprazole inhibits marble-burying behavior via 5-hydroxytryptamine (5-HT)1A receptor-independent mechanisms Fulltext Access 6 Pages 2008
The critical role of invading peripheral macrophage-derived interleukin-6 in vincristine-induced mechanical allodynia in mice Fulltext Access 6 Pages 2008
Centrally administered neuromedin U elevates plasma adrenaline by brain prostanoid TP receptor-mediated mechanisms in rats Fulltext Access 6 Pages 2008