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Daneshyari Pharmacology Journas Latest Articles

Pharmacology Research Articles

Effect of PPADS on achondroplasic chondrocytes: Inhibition of FGF receptor type 3 over-activity
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Dose-dependent beneficial hemodynamic effects of BAY 41-2272 in a canine model of acute pulmonary thromboembolism
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Role of the spinal cord heme oxygenase–carbon monoxide–cGMP pathway in the nociceptive response of rats
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Stimulation of suicidal erythrocyte death by amantadine
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Antioxidant and pancreas-protective effect of aucubin on rats with streptozotocin-induced diabetes
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Involvement of peroxynitrite in pollen-induced nasal blockage in guinea pigs
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Geldanamycin enhances hepatocyte growth factor stimulation of eNOS phosphorylation in endothelial cells
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The selective 5-HT6 receptor antagonist SB-399885 enhances anti-immobility action of antidepressants in rats
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Effects of pentoxifylline and its metabolites on platelet aggregation in whole blood from healthy humans
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Negative regulation of cyclin-dependent kinase 5 targets by protein kinase C
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Brain nuclear factor kappa B is involved in the corticotropin-releasing factor-induced central activation of sympatho-adrenomedullary outflow in rats
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Neutering affects urinary bladder function by different mechanisms in male and female dogs
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Systemic administration of [6]-gingerol, a pungent constituent of ginger, induces hypothermia in rats via an inhibitory effect on metabolic rate
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Evaluation of taurine as a biomarker of liver damage in paracetamol poisoning
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Reversal effect of a macrocyclic bisbibenzyl plagiochin E on multidrug resistance in adriamycin-resistant K562/A02 cells
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Differential regulation of prostaglandin synthesis in neonatal rat microglia and astrocytes by somatostatin
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LPK-26, a novel κ-opioid receptor agonist with potent antinociceptive effects and low dependence potential
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Aconitine induces prolonged seizure-like events in rat neocortical brain slices
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Effect of co-administration of a serotonin–noradrenaline reuptake inhibitor and a dopamine agonist on extracellular monoamine concentrations in rats
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Sustained morphine treatment augments basal CGRP release from cultured primary sensory neurons in a Raf-1 dependent manner
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Effects of 18α-glycyrrhizin on the pharmacodynamics and pharmacokinetics of glibenclamide in alloxan-induced diabetic rats
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Preparation of Inhalable Salbutamol Sulphate Using Reactive High Gravity Controlled Precipitation
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Assessment of Presystemic and Systemic Intestinal Availability of Orally Administered Drugs Using In Vitro and In Vivo Data in Humans: Intestinal Sulfation Metabolism Impacts Presystemic Availability Much More Than Systemic Availability of Salbutamol, SUL
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Inside the medicine cabinet: Making children's medicines a grown‐up issue
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On the Identification of Slip Planes in Organic Crystals Based on Attachment Energy Calculation
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Vasorelaxant effect of taurine is diminished by tetraethylammonium in rat isolated arteries
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Increased bias to report heat or pain following emotional priming of pain-related fear
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Contribution of prostaglandin D2 via prostanoid DP receptor to nasal hyperresponsiveness in guinea pigs repeatedly exposed to antigen
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Aripiprazole, an atypical antipsychotic, prevents the motor hyperactivity induced by psychotomimetics and psychostimulants in mice
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Antipsychotic-induced suppression of locomotion in juvenile, adolescent and adult rats
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Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1
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Affinity of cyamemazine metabolites for serotonin, histamine and dopamine receptor subtypes
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The regulation of mitochondrial respiration by opening of mKCa channels is age-dependent
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Transdermally administered nitric oxide by application of acidified nitrite increases blood flow in rat epigastric island skin flaps
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Gonadal hormone modulation of the behavioral effects of Δ9-tetrahydrocannabinol in male and female rats
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Effects of resveratrol on calcium regulation in rats with severe acute pancreatitis
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In vivo study on the effects of α1-adrenoceptor antagonists on intraurethral pressure in the prostatic urethra and intraluminal pressure in the vas deferens in male dogs
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Alterations in spontaneous contractions of rat ileum and jejunum after peritonitis
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Connecting with the larger purpose of our work
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Effect of prostanoid EP4 receptor antagonist, CJ-042,794, in rat models of pain and inflammation
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Selective serotonin reuptake inhibitors fluvoxamine and paroxetine restore forced exercise-induced temperature dysregulation in ovariectomized mice
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The effects of physiological and pharmacological weight loss on adiponectin and leptin mRNA levels in the rat epididymal adipose tissue
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Vasorelaxant effect of isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate, a novel metabolite from Salvia miltiorrhiza, on isolated rat mesenteric artery
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Effects of selective inhibition of N-acetylated-α-linked-acidic dipeptidase (NAALADase) on mice in learning and memory tasks
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Subchronic fluoride intake induces impairment in habituation and active avoidance tasks in rats
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Quantitative study of [(pF)Phe4,Arg14,Lys15]nociceptin/orphanin FQ-NH2 (UFP-102) at NOP receptors in rat periaqueductal gray slices
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Comparison of the induction of P-glycoprotein activity by nucleotide, nucleoside, and non-nucleoside reverse transcriptase inhibitors
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Doxazosin induces apoptosis of cells expressing hERG K+ channels
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Inducible expression and pharmacological characterization of the mouse metabotropic glutamate 5b receptor
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Effect of femto to nano molar concentrations of prostaglandin analogues on pregnant rat uterine contractility
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The cannabinoid receptor agonist CP-55,940 and ethyl arachidonate interfere with [3H]batrachotoxinin A 20 α-benzoate binding to sodium channels and inhibit sodium channel function
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Cocoa flavanols and the nitric oxide-pathway: targeting endothelial dysfunction by dietary intervention
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Global challenges in the development and delivery of paediatric antiretrovirals
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Using ontogeny information to build predictive models for drug elimination
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Novel approaches to the treatment of cachexia
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Strategic approaches to developing drug treatments for ALS
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Development and application of Hsp90 inhibitors
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Motilin, ghrelin and related neuropeptides as targets for the treatment of GI diseases
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Dynamic changes in parameters of redox balance after mild heat stress in aged laying hens (Gallus gallus domesticus)
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Ethanol-induced increased endogenous homocysteine levels and decreased ratios of SAM/SAH are only partially attenuated by exogenous glycine in developing chick brains
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Shrimp thioredoxin is a potent antioxidant protein
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Modulation of antioxidant and detoxification responses mediated by lipoic acid in the fish Corydoras paleatus (Callychthyidae)
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Cortisol response to acute stress in jundiá Rhamdia quelen acutely exposed to sub-lethal concentrations of agrichemicals
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Mechanisms of arterial remodeling and neointima formation: an updated view on the chemokine system
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Identification and characterization of two mtf-1 genes in common carp
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Cadmium is deposited in the gut content of larvae of the beetle Tenebrio molitor and involves a Cd-binding protein of the low cysteine type
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Differential pattern of Cu/Zn superoxide dismutase isoforms in relation to tidal spatio-temporal changes in the blue mussel Mytilus edulis
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Pro-inflammatory effect in mice of CvL, a lectin from the marine sponge Cliona varians
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20(S)-protopanaxadiol and the ginsenoside Rh2 inhibit Na+ channel-activated depolarization and Na+ channel-dependent amino acid neurotransmitter release in synaptic fractions isolated from mammalian brain
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Interaction of diethylstilbestrol and ioxynil with transthyretin in chicken serum
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Histamine-induced modulation of vascular tone in the isolated chicken basilar artery: A possible involvement of endothelium
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Polysaccharides from Astragalus membranaceus promote phagocytosis and superoxide anion (O2−) production by coelomocytes from sea cucumber Apostichopus japonicus in vitro
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The role of antibodies specific for toxic sPLA2s and haemorrhagins in neutralizing potential of antisera raised against Vipera ammodytes ammodytes venom
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Exposure to mercury reduces cold tolerance in the springtail Folsomia candida
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Effects of ozone, ultraviolet and peracetic acid disinfection of a primary-treated municipal effluent on the Immune system of rainbow trout (Oncorhynchus mykiss)
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Recombinant therapeutic protein production in cultivated mammalian cells: current status and future prospects
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Discovery of a Stable Molecular Complex of an API With HCl: A Long Journey to a Conventional Salt
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Advances in lung imaging techniques for the treatment of respiratory disease
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Future antidepressant targets: neurotrophic factors and related signaling cascades
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Cognitive enhancing drugs for schizophrenia
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Stem cell therapies in cardiovascular disease: A ‘realistic’ appraisal
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Gene therapy of inherited skin adhesion disorders
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Cystic fibrosis: recent advances in lung-directed therapies
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Therapeutics of X-linked adrenoleukodystrophy
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Multiple roles for BMP signaling in cardiac development
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Advances and perspectives in human and mouse embryonic stem cell bioprocessing
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Alternative routes of administration for systemic delivery of protein pharmaceuticals
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Computational design of protein therapeutics
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Regional differences in mRNA responses in blue mussels within the Baltic proper
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Ion channel screening – automated patch clamp on the rise
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Evolution in thinking and processes?
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Models of astrocytic Ca2+ dynamics and epilepsy
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Use of larger species such as dog and pig as model systems to study cardiac disease
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Rat as a model system for hypertension drug discovery
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The rat as a model for cardiovascular disease
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Lessons from the lily pad: using Xenopus to understand heart disease
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Zebrafish as a model for cardiovascular development and disease
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Acne – a multifaceted problem
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Targeted therapeutic strategies in malignant melanoma
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Barrier repair trumps immunology in the pathogenesis and therapy of atopic dermatitis
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