6-O-Angeloylenolin induces apoptosis through a mitochondrial/caspase and NF-κB pathway in human leukemia HL60 cells Fulltext Access 9 Pages 2008
Topical amethocaine gel 4% for intramuscular injection in term neonates: A double-blind, placebo-controlled, randomized trial Fulltext Access 9 Pages 2008
Colistin serum concentrations after intravenous administration in critically ill patients with serious multidrug-resistant, gram-negative bacilli infections: A prospective, open-label, uncontrolled study Fulltext Access 9 Pages 2008
In vitro stability, potency, and dissolution of duloxetine enteric-coated pellets after exposure to applesauce, apple juice, and chocolate pudding Fulltext Access 9 Pages 2008
Use of glargine in pregnant women with Type 1 diabetes mellitus: A case-control study Fulltext Access 9 Pages 2008
Persistence with Migraine Prophylactic Treatment and Acute Migraine Medication Utilization in the Managed Care Setting Fulltext Access 9 Pages 2008
Oral versus injectable antipsychotic treatment in early psychosis: Post hoc comparison of two studies Fulltext Access 9 Pages 2008
Relative bioavailability of tizanidine hydrochloride capsule formulation compared with capsule contents administered in applesauce: A single-dose, open-label, randomized, two-way, crossover study in fasted healthy adult subjects Fulltext Access 9 Pages 2008
Titin expression in human articular cartilage and cultured chondrocytes : A novel component in articular cartilage biomechanical sensing? Fulltext Access 9 Pages 2008
Short-term tolerability of a nonazapirone selective serotonin 1A agonist in adults with generalized anxiety disorder: A 28-day, open-label study Fulltext Access 9 Pages 2008
Resveratrol inhibits hypoxia-induced metastasis potential enhancement by restricting hypoxia-induced factor-1α expression in colon carcinoma cells Fulltext Access 9 Pages 2008
Romidepsin (depsipeptide) induced cell cycle arrest, apoptosis and histone hyperacetylation in lung carcinoma cells (A549) are associated with increase in p21 and hypophosphorylated retinoblastoma proteins expression Fulltext Access 9 Pages 2008
Indole-3-carbinol enhances anti-proliferative, but not anti-invasive effects of oxaliplatin in colorectal cancer cell lines Fulltext Access 9 Pages 2008
Histone deacetylase inhibitor SAHA induces ERα degradation in breast cancer MCF-7 cells by CHIP-mediated ubiquitin pathway and inhibits survival signaling Fulltext Access 9 Pages 2008
Geldanamycin inhibits tyrosine phosphorylation-dependent NF-κB activation Fulltext Access 9 Pages 2008
Metyrapone prevents cortisone-induced preadipocyte differentiation by depleting luminal NADPH of the endoplasmic reticulum Fulltext Access 9 Pages 2008
Novel iminobenzoxathiolone compound inhibits nuclear factor-κB activation targeting inhibitory κB kinase β and down-regulating interleukin-1β expression in lipopolysaccharide-activated macrophages Fulltext Access 9 Pages 2008
A COX-2 metabolite of the endogenous cannabinoid, 2-arachidonyl glycerol, mediates suppression of IL-2 secretion in activated Jurkat T cells Fulltext Access 9 Pages 2008
Different initial steps of apoptosis induced by two types of antineoplastic drugs Fulltext Access 9 Pages 2008
Astragaloside IV improves high glucose-induced podocyte adhesion dysfunction via α3β1 integrin upregulation and integrin-linked kinase inhibition Fulltext Access 9 Pages 2008
Characterization of Eltenac and novel COX-2 selective thiopheneacetic acid analogues in vitro and in vivo Fulltext Access 9 Pages 2008
Baicalin inhibits macrophage activation by lipopolysaccharide and protects mice from endotoxin shock Fulltext Access 9 Pages 2008
Therapeutic angiogenesis of mouse hind limb ischemia by novel peptide activating GRP78 receptor on endothelial cells Fulltext Access 9 Pages 2008
On the energy-dependence of Hoechst 33342 transport by the ABC transporter LmrA Fulltext Access 9 Pages 2008
Modulation of the human equilibrative nucleoside transporter1 (hENT1) activity by IL-4 and PMA in B cells from chronic lymphocytic leukemia Fulltext Access 9 Pages 2008
Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory and analgesic effects of the natural marine compound lemnalol from Formosan soft coral Lemnalia cervicorni Fulltext Access 9 Pages 2008
Regulatory mechanisms of IL-2 and IFNγ suppression by quercetin in T helper cells Fulltext Access 9 Pages 2008
Prescribing of β-blockers after myocardial infarction: A preliminary study of physician motivations and barriers Fulltext Access 9 Pages 2008
Analysis of the association between polypharmacy and socioeconomic position among elderly aged ≥77 years in Sweden Fulltext Access 9 Pages 2008
Preferences of adult patients with allergic rhinitis for the sensory attributes of fluticasone furoate versus fluticasone propionate nasal sprays: A randomized, multicenter, double-blind, single-dose, crossover study Fulltext Access 9 Pages 2008
The effects of atypical and conventional antipsychotics on reduced processing speed and psychomotor slowing in schizophrenia: A cross-sectional exploratory study Fulltext Access 9 Pages 2008
Metformin use in children with nonalcoholic fatty liver disease: An open-label, 24-month, observational pilot study Fulltext Access 9 Pages 2008
Role of patient experience in antidepressant adherence: A retrospective data analysis Fulltext Access 9 Pages 2008
C-terminal mini-PEGylation of glucose-dependent insulinotropic polypeptide exhibits metabolic stability and improved glucose homeostasis in dietary-induced diabetes Fulltext Access 9 Pages 2008
Increased mitochondrial DNA copy-number in CEM cells resistant to delayed toxicity of 2′,3′-dideoxycytidine Fulltext Access 9 Pages 2008
Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus Fulltext Access 9 Pages 2008
Oxidation of 5-methoxy-N,N-diisopropyltryptamine in rat liver microsomes and recombinant cytochrome P450 enzymes Fulltext Access 9 Pages 2008
Hepatic alteration of tryptophan metabolism in an acute porphyria model: Its relation with gluconeogenic blockage Fulltext Access 9 Pages 2008
Cyclooxygenase-2-dependent and -independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid Fulltext Access 9 Pages 2008
Differential inactivation of polymorphic variants of human O6-alkylguanine-DNA alkyltransferase Fulltext Access 9 Pages 2008
In vitro characterisation of human renal and hepatic frusemide glucuronidation and identification of the UDP-glucuronosyltransferase enzymes involved in this pathway Fulltext Access 9 Pages 2008
Over-the-counter analgesics normalize blood glucose and body composition in mice fed a high fat diet Fulltext Access 9 Pages 2008
The anti-proliferative potency of celecoxib is not a class effect of coxibs Fulltext Access 9 Pages 2008
Effects of V2-receptor antagonist tolvaptan and the loop diuretic furosemide in rats with heart failure Fulltext Access 9 Pages 2008
Homeostasis of retinol in lecithin: Retinol acyltransferase gene knockout mice fed a high retinol diet Fulltext Access 9 Pages 2008
Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine Fulltext Access 9 Pages 2008
7-Deaza-6-benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: Activities and selective toxicities Fulltext Access 9 Pages 2008
Possible role of an ischemic preconditioning-like response mechanism in KATP channel opener-mediated protection against streptozotocin-induced suppression of rat pancreatic islet function Fulltext Access 9 Pages 2008
Synthesis of 1-β-d-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus Fulltext Access 9 Pages 2008
A clathrin–dynamin-dependent endocytic pathway for the uptake of HIV-1 by direct T cell–T cell transmission Fulltext Access 9 Pages 2008
Anti-herpes simplex virus (HSV-1) activity of oxyresveratrol derived from Thai medicinal plant: Mechanism of action and therapeutic efficacy on cutaneous HSV-1 infection in mice Fulltext Access 9 Pages 2008
Retinoids inhibit measles virus in vitro via nuclear retinoid receptor signaling pathways Fulltext Access 9 Pages 2008
Vector design for liver-specific expression of multiple interfering RNAs that target hepatitis B virus transcripts Fulltext Access 9 Pages 2008
Cell shape, cell–cell contact, cell–extracellular matrix contact and cell polarity are all required for the maximum induction of CYP2B1 and CYP2B2 gene expression by phenobarbital in adult rat cultured hepatocytes Fulltext Access 9 Pages 2008
Oxaliplatin activity in selected and unselected human ovarian and colorectal cancer cell lines Fulltext Access 9 Pages 2008
Histone H2AX phosphorylation as a molecular pharmacological marker for DNA interstrand crosslink cancer chemotherapy Fulltext Access 9 Pages 2008
The relative contribution of human cytochrome P450 isoforms to the four caffeine oxidation pathways: An in vitro comparative study with cDNA-expressed P450s including CYP2C isoforms Fulltext Access 9 Pages 2008
A comparative study of the effects of quercetin and its glucuronide and sulfate metabolites on human neutrophil function in vitro Fulltext Access 9 Pages 2008
Comparison of CYP1A2 and NAT2 phenotypes between black and white smokers Fulltext Access 9 Pages 2008
Dexamethasone inhibits basic fibroblast growth factor-stimulated gastric epithelial cell proliferation Fulltext Access 9 Pages 2008
JNK inhibitor SP600125 is a partial agonist of human aryl hydrocarbon receptor and induces CYP1A1 and CYP1A2 genes in primary human hepatocytes Fulltext Access 9 Pages 2008
Cinnamaldehyde suppresses toll-like receptor 4 activation mediated through the inhibition of receptor oligomerization Fulltext Access 9 Pages 2008
Neuroprotective antioxidant STAZN protects against myocardial ischemia/reperfusion injury Fulltext Access 9 Pages 2008
Effects of lovastatin on Rho isoform expression, activity, and association with guanine nucleotide dissociation inhibitors Fulltext Access 9 Pages 2008
Is the anti-psychotic, 10-(3-(dimethylamino)propyl)phenothiazine (promazine), a potential drug with which to treat SARS infections?: Lack of efficacy of promazine on SARS-CoV replication in a mouse model Fulltext Access 9 Pages 2008
Molecular basis for the interaction of four different classes of substrates and inhibitors with human aromatase Fulltext Access 9 Pages 2008
Metabolic transformation has a profound effect on anti-inflammatory activity of flavonoids such as quercetin: Lack of association between antioxidant and lipoxygenase inhibitory activity Fulltext Access 9 Pages 2008
Modulation of intracellular Ca2+ signalling in HeLa cells by the apoptotic cell death enhancer PK11195 Fulltext Access 9 Pages 2008
Action of resveratrol alone or in combination with roscovitine, a CDK inhibitor, on cell cycle progression in human HL-60 leukemia cells Fulltext Access 9 Pages 2008
c-Jun N-terminal kinases mediate Fas-induced neurite regeneration in PC12 cells Fulltext Access 9 Pages 2008
Erlotinib and gefitinib for the treatment of myelodysplastic syndrome and acute myeloid leukemia: A preclinical comparison Fulltext Access 9 Pages 2008
Post-transcriptional control of gene expression through subcellular relocalization of mRNA binding proteins Fulltext Access 9 Pages 2008
Acetaminophen normalizes glucose homeostasis in mouse models for diabetes Fulltext Access 9 Pages 2008
Cyanidin 3-glucoside protects 3T3-L1 adipocytes against H2O2- or TNF-α-induced insulin resistance by inhibiting c-Jun NH2-terminal kinase activation Fulltext Access 9 Pages 2008